Metaflumizone

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  • Identifiers

    CAS number
    139968-49-3

    Molecular formula
    C24H16F6N4O2

    SMILES
    C1=CC(=CC(=C1)C(F)(F)F)/C(=N/NC(=O)NC2=CC=C(C=C2)OC(F)(F)F)/CC3=CC=C(C=C3)C#N

    Safety labels

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 41.61%
    Grape 30.77%
    Fruity 30.13%
    Floral 27.43%
    Sweet 24.66%
    Savory 24.44%
    Citrus 23.67%
    Animal 23.47%
    Bitter 22.02%
    Fresh 21.85%

     

    Flavor
    Bitter 71.74%
    Odorless 44.71%
    Bland 26.04%
    Mild 25.3%
    Nitrile 20.05%
    Sweet-like 19.89%
    Very strong 18.58%
    Cedarleaf 18.46%
    Scallion 18.41%
    Indole 18.39%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    6.2

    pKa est.
    6.23 (neutral)

    Molecular weight
    506.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    591°C

    Flash point

    • 211.7 ˚C est.

  • Synonyms

    • Metaflumizone
    • 139968-49-3
    • 71I50E2UDI
    • 1-[(E)-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]amino]-3-[4-(trifluoromethoxy)phenyl]urea
    • 2-(2-(4-cyanophenyl)-1-(3-(trifluoromethyl)phenyl)ethylidene)-N-(4-(trifluoromethoxy)phenyl)hydrazinecarboxamide
    • BAS-320I
    • DTXSID6040373
    • DTXCID60196514
    • 1-((E)-(2-(4-cyanophenyl)-1-(3-(trifluoromethyl)phenyl)ethylidene)amino)-3-(4-(trifluoromethoxy)phenyl)urea
    • PROMERIS
    • ALVERDE (BASF)
    • SIESTA (BASF)
    • RefChem:811194
    • PROMERIS (FORT DODGE)
    • PROMERIS DUO COMPONENT METAFLUMIZONE
    • 604-167-6
    • (E)-Metaflumizone
    • 852403-68-0
    • Metaflumizone (E-isomer)
    • Metaflumizone, (E)-
    • COL1OR95DS
    • Alverde
    • Hydrazinecarboxamide, 2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]-
    • (2E)-2-(2-(4-Cyanophenyl)-1-(3-(trifluoromethyl)phenyl)ethylidene)-N-(4-(trifluoromethoxy)phenyl)hydrazinecarboxamide
    • Hydrazinecarboxamide, 2-(2-(4-cyanophenyl)-1-(3-(trifluoromethyl)phenyl)ethylidene)-N-(4-(trifluoromethoxy)phenyl)-, (2E)-
    • Metaflumizone [ISO]
    • UNII-71I50E2UDI
    • C24H16F6N4O2
    • E-Metaflumizone
    • BASF 320
    • BAS 320
    • (2E)-2-[2-(4-Cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]hydrazinecarboxamide; (E)-Metaflumizone
    • NNI 0250
    • MFCD08690508
    • BAS 320001
    • BAS 320021
    • bas 320i
    • UNII-COL1OR95DS
    • SCHEMBL617627
    • SCHEMBL29364764
    • DTXSID501009397
    • MSK157832
    • DA-50941
    • Hydrazinecarboxamide,2-[2-(4-cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene]-N-[4-(trifluoromethoxy)phenyl]-
    • Metaflumizone, PESTANAL(R), analytical standard
    • (E)-Metaflumizone 100 microg/mL in Acetonitrile
    • (2E)-2-{2-(4-Cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene}-N-[4-(trifluoromethoxy)phenyl]hydrazine-1-carboxamide
    • Pesticide4_Metaflumizone_C24H16F6N4O2_(2E)-2-{2-(4-Cyanophenyl)-1-[3-(trifluoromethyl)phenyl]ethylidene}-N-[4-(trifluoromethoxy)phenyl]hydrazinecarboxamide
    • 139968-49-3

  • Applications

    Metaflumizone is a crop insecticide used primarily in agriculture to control key pests on a range of crops. Real-world applications include foliar sprays on field crops and ornamentals in nurseries or greenhouses, protection of fruit crops, and protection of vegetable crops; it is deployed in both field and protected cultivation settings and is commonly formulated in combination with other insecticides within integrated pest management (IPM) programs. Users should comply with local regulations and formulation limits to ensure safe and effective use.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 9.42
    methanol 15.01
    isopropanol 4.49
    water 0.0
    ethyl acetate 8.98
    n-propanol 6.7
    acetone 28.25
    n-butanol 4.55
    acetonitrile 5.64
    DMF 48.9
    toluene 3.24
    isobutanol 2.94
    1,4-dioxane 15.52
    methyl acetate 14.9
    THF 50.69
    2-butanone 27.13
    n-pentanol 3.03
    sec-butanol 4.61
    n-hexane 0.04
    ethylene glycol 2.43
    NMP 37.6
    cyclohexane 0.07
    DMSO 76.29
    n-butyl acetate 4.82
    n-octanol 1.56
    chloroform 10.15
    n-propyl acetate 5.31
    acetic acid 14.57
    dichloromethane 12.08
    cyclohexanone 24.69
    propylene glycol 3.55
    isopropyl acetate 4.18
    DMAc 52.36
    2-ethoxyethanol 12.7
    isopentanol 2.5
    n-heptane 0.08
    ethyl formate 9.3
    1,2-dichloroethane 7.77
    n-hexanol 2.44
    2-methoxyethanol 27.36
    isobutyl acetate 1.67
    tetrachloromethane 0.53
    n-pentyl acetate 4.58
    transcutol 20.52
    n-heptanol 1.95
    ethylbenzene 0.87
    MIBK 3.9
    2-propoxyethanol 14.58
    tert-butanol 2.84
    MTBE 2.79
    2-butoxyethanol 9.38
    propionic acid 8.36
    o-xylene 1.27
    formic acid 10.91
    diethyl ether 4.85
    m-xylene 1.0
    p-xylene 0.87
    chlorobenzene 2.12
    dimethyl carbonate 7.69
    n-octane 0.04
    formamide 20.3
    cyclopentanone 41.38
    2-pentanone 13.46
    anisole 4.03
    cyclopentyl methyl ether 4.62
    gamma-butyrolactone 33.77
    1-methoxy-2-propanol 15.58
    pyridine 22.03
    3-pentanone 10.16
    furfural 29.55
    n-dodecane 0.05
    diethylene glycol 9.53
    diisopropyl ether 0.49
    tert-amyl alcohol 3.29
    acetylacetone 16.19
    n-hexadecane 0.06
    acetophenone 5.36
    methyl propionate 11.87
    isopentyl acetate 2.79
    trichloroethylene 16.51
    n-nonanol 1.75
    cyclohexanol 2.54
    benzyl alcohol 4.45
    2-ethylhexanol 1.12
    isooctanol 1.22
    dipropyl ether 2.53
    1,2-dichlorobenzene 1.52
    ethyl lactate 4.16
    propylene carbonate 8.54
    n-methylformamide 24.87
    2-pentanol 2.02
    n-pentane 0.09
    1-propoxy-2-propanol 8.09
    1-methoxy-2-propyl acetate 7.37
    2-(2-methoxypropoxy) propanol 8.67
    mesitylene 0.34
    ε-caprolactone 15.88
    p-cymene 0.56
    epichlorohydrin 33.92
    1,1,1-trichloroethane 3.07
    2-aminoethanol 5.36
    morpholine-4-carbaldehyde 30.45
    sulfolane 42.1
    2,2,4-trimethylpentane 0.04
    2-methyltetrahydrofuran 11.87
    n-hexyl acetate 4.57
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 11.66
    sec-butyl acetate 2.54
    tert-butyl acetate 3.43
    decalin 0.03
    glycerin 6.44
    diglyme 21.55
    acrylic acid 9.43
    isopropyl myristate 1.63
    n-butyric acid 8.34
    acetyl acetate 4.46
    di(2-ethylhexyl) phthalate 2.33
    ethyl propionate 5.02
    nitromethane 36.4
    1,2-diethoxyethane 6.78
    benzonitrile 4.18
    trioctyl phosphate 1.56
    1-bromopropane 3.7
    gamma-valerolactone 54.46
    n-decanol 1.28
    triethyl phosphate 1.7
    4-methyl-2-pentanol 0.79
    propionitrile 5.96
    vinylene carbonate 9.34
    1,1,2-trichlorotrifluoroethane 21.37
    DMS 5.15
    cumene 0.39
    2-octanol 1.11
    2-hexanone 7.72
    octyl acetate 2.78
    limonene 0.75
    1,2-dimethoxyethane 21.73
    ethyl orthosilicate 1.41
    tributyl phosphate 1.72
    diacetone alcohol 7.06
    N,N-dimethylaniline 2.06
    acrylonitrile 10.38
    aniline 4.62
    1,3-propanediol 7.86
    bromobenzene 1.61
    dibromomethane 6.14
    1,1,2,2-tetrachloroethane 11.36
    2-methyl-cyclohexyl acetate 2.4
    tetrabutyl urea 3.66
    diisobutyl methanol 0.55
    2-phenylethanol 4.04
    styrene 1.19
    dioctyl adipate 3.38
    dimethyl sulfate 12.97
    ethyl butyrate 3.9
    methyl lactate 10.12
    butyl lactate 4.93
    diethyl carbonate 2.39
    propanediol butyl ether 6.87
    triethyl orthoformate 2.69
    p-tert-butyltoluene 0.46
    methyl 4-tert-butylbenzoate 5.11
    morpholine 20.78
    tert-butylamine 1.04
    n-dodecanol 0.89
    dimethoxymethane 26.24
    ethylene carbonate 6.48
    cyrene 8.49
    2-ethoxyethyl acetate 9.39
    2-ethylhexyl acetate 2.17
    1,2,4-trichlorobenzene 2.69
    4-methylpyridine 12.87
    dibutyl ether 1.82
    2,6-dimethyl-4-heptanol 0.55
    DEF 13.42
    dimethyl isosorbide 11.04
    tetrachloroethylene 5.92
    eugenol 6.72
    triacetin 5.98
    span 80 6.3
    1,4-butanediol 2.45
    1,1-dichloroethane 5.21
    2-methyl-1-pentanol 2.0
    methyl formate 20.81
    2-methyl-1-butanol 2.97
    n-decane 0.09
    butyronitrile 5.11
    3,7-dimethyl-1-octanol 1.08
    1-chlorooctane 0.61
    1-chlorotetradecane 0.25
    n-nonane 0.07
    undecane 0.07
    tert-butylcyclohexane 0.02
    cyclooctane 0.02
    cyclopentanol 4.4
    tetrahydropyran 9.94
    tert-amyl methyl ether 2.73
    2,5,8-trioxanonane 15.46
    1-hexene 0.49
    2-isopropoxyethanol 5.75
    2,2,2-trifluoroethanol 4.31
    methyl butyrate 6.77

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction