Mangiferolic Acid

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  • Identifiers

    CAS number
    4184-34-3

    Molecular formula
    C30H48O3

    SMILES
    C[C@H](CC/C=C(\C)/C(=O)O)[C@H]1CC[C@@]2([C@@]1(CC[C@]34[C@H]2CC[C@@H]5[C@]3(C4)CC[C@@H](C5(C)C)O)C)C

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  • Odor profile

    Fragrance
    Woody 88.73%
    Sandalwood 59.38%
    Amber 57.92%
    Dry 48.08%
    Cedar 44.53%
    Musk 41.07%
    Vetiver 39.9%
    Balsamic 38.32%
    Powdery 37.22%
    Animal 31.46%

     

    Flavor
    Woody 67.89%
    Balsam 34.95%
    Sweet 32.23%
    Wood 29.23%
    Herbal 28.74%
    Pine 27.98%
    Camphor 26.81%
    Balsamic 23.19%
    Sandalwood 23.12%
    Fir needle 22.87%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    8.5

    pKa est.
    7.1 (neutral)

    Molecular weight
    456.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    311°C

    Flash point

    • 210.32 ˚C est.

  • Synonyms

    • Mangiferolic acid
    • 4184-34-3
    • (E,6R)-6-[(1S,3R,6S,8R,11S,12S,15R,16R)-6-hydroxy-7,7,12,16-tetramethyl-15-pentacyclo[9.7.0.01,3.03,8.012,16]octadecanyl]-2-methylhept-2-enoic acid
    • Isomangiferolate
    • (E,6R)-6-((1S,3R,6S,8R,11S,12S,15R,16R)-6-hydroxy-7,7,12,16-tetramethyl-15-pentacyclo(9.7.0.01,3.03,8.012,16)octadecanyl)-2-methylhept-2-enoic acid
    • RefChem:155619
    • CHEMBL552007
    • SCHEMBL31097460
    • AKOS040762020
    • FS-9305
    • CS-0023898
    • 4184-34-3

  • Applications

    Mangiferolic acid (CAS 4184-34-3) is primarily encountered as an intermediate in organic synthesis and is being evaluated for use as an antioxidant and functional additive in cosmetics and polymer systems; it is considered as a performance additive for coatings and inks to enhance aging resistance; it is also explored as a potential intermediate in pharmaceutical and fine-chemical production, with suitability depending on local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 4.73
    methanol 2.85
    isopropanol 3.95
    water 0.01
    ethyl acetate 2.76
    n-propanol 5.04
    acetone 3.17
    n-butanol 4.62
    acetonitrile 0.96
    DMF 7.64
    toluene 2.09
    isobutanol 3.14
    1,4-dioxane 6.78
    methyl acetate 2.03
    THF 12.85
    2-butanone 3.95
    n-pentanol 3.01
    sec-butanol 2.42
    n-hexane 0.15
    ethylene glycol 0.57
    NMP 6.45
    cyclohexane 0.14
    DMSO 3.75
    n-butyl acetate 3.26
    n-octanol 1.89
    chloroform 6.4
    n-propyl acetate 2.09
    acetic acid 2.84
    dichloromethane 3.32
    cyclohexanone 5.62
    propylene glycol 1.17
    isopropyl acetate 3.57
    DMAc 10.08
    2-ethoxyethanol 6.86
    isopentanol 3.73
    n-heptane 0.14
    ethyl formate 1.31
    1,2-dichloroethane 2.17
    n-hexanol 3.83
    2-methoxyethanol 9.06
    isobutyl acetate 2.31
    tetrachloromethane 1.31
    n-pentyl acetate 4.76
    transcutol 16.62
    n-heptanol 3.63
    ethylbenzene 1.15
    MIBK 4.07
    2-propoxyethanol 16.16
    tert-butanol 3.14
    MTBE 3.24
    2-butoxyethanol 12.1
    propionic acid 2.3
    o-xylene 1.33
    formic acid 1.23
    diethyl ether 3.17
    m-xylene 1.77
    p-xylene 1.23
    chlorobenzene 1.95
    dimethyl carbonate 2.3
    n-octane 0.07
    formamide 1.78
    cyclopentanone 6.04
    2-pentanone 4.06
    anisole 3.42
    cyclopentyl methyl ether 3.89
    gamma-butyrolactone 5.09
    1-methoxy-2-propanol 11.41
    pyridine 5.35
    3-pentanone 3.05
    furfural 4.65
    n-dodecane 0.03
    diethylene glycol 7.29
    diisopropyl ether 1.21
    tert-amyl alcohol 2.42
    acetylacetone 4.88
    n-hexadecane 0.04
    acetophenone 3.22
    methyl propionate 3.18
    isopentyl acetate 4.51
    trichloroethylene 5.2
    n-nonanol 2.38
    cyclohexanol 2.14
    benzyl alcohol 3.34
    2-ethylhexanol 1.96
    isooctanol 3.03
    dipropyl ether 2.46
    1,2-dichlorobenzene 1.96
    ethyl lactate 2.16
    propylene carbonate 2.75
    n-methylformamide 2.75
    2-pentanol 2.37
    n-pentane 0.18
    1-propoxy-2-propanol 10.69
    1-methoxy-2-propyl acetate 8.42
    2-(2-methoxypropoxy) propanol 7.43
    mesitylene 1.05
    ε-caprolactone 5.13
    p-cymene 1.05
    epichlorohydrin 6.78
    1,1,1-trichloroethane 2.47
    2-aminoethanol 2.37
    morpholine-4-carbaldehyde 10.75
    sulfolane 6.38
    2,2,4-trimethylpentane 0.15
    2-methyltetrahydrofuran 4.15
    n-hexyl acetate 4.53
    isooctane 0.15
    2-(2-butoxyethoxy)ethanol 9.88
    sec-butyl acetate 2.0
    tert-butyl acetate 4.79
    decalin 0.15
    glycerin 2.35
    diglyme 16.02
    acrylic acid 1.91
    isopropyl myristate 1.44
    n-butyric acid 4.36
    acetyl acetate 2.36
    di(2-ethylhexyl) phthalate 2.49
    ethyl propionate 2.23
    nitromethane 3.33
    1,2-diethoxyethane 4.5
    benzonitrile 1.85
    trioctyl phosphate 1.72
    1-bromopropane 1.44
    gamma-valerolactone 13.23
    n-decanol 1.25
    triethyl phosphate 1.81
    4-methyl-2-pentanol 2.2
    propionitrile 1.82
    vinylene carbonate 3.06
    1,1,2-trichlorotrifluoroethane 6.54
    DMS 3.4
    cumene 0.92
    2-octanol 1.64
    2-hexanone 2.93
    octyl acetate 1.99
    limonene 1.14
    1,2-dimethoxyethane 7.83
    ethyl orthosilicate 2.21
    tributyl phosphate 1.41
    diacetone alcohol 6.11
    N,N-dimethylaniline 2.77
    acrylonitrile 1.99
    aniline 2.99
    1,3-propanediol 4.59
    bromobenzene 1.79
    dibromomethane 2.3
    1,1,2,2-tetrachloroethane 4.32
    2-methyl-cyclohexyl acetate 3.15
    tetrabutyl urea 2.14
    diisobutyl methanol 1.5
    2-phenylethanol 5.5
    styrene 1.15
    dioctyl adipate 2.38
    dimethyl sulfate 3.45
    ethyl butyrate 2.49
    methyl lactate 3.21
    butyl lactate 5.0
    diethyl carbonate 1.57
    propanediol butyl ether 6.67
    triethyl orthoformate 3.23
    p-tert-butyltoluene 1.17
    methyl 4-tert-butylbenzoate 6.9
    morpholine 8.95
    tert-butylamine 1.62
    n-dodecanol 0.63
    dimethoxymethane 9.29
    ethylene carbonate 2.67
    cyrene 6.17
    2-ethoxyethyl acetate 8.05
    2-ethylhexyl acetate 3.32
    1,2,4-trichlorobenzene 2.82
    4-methylpyridine 4.38
    dibutyl ether 1.18
    2,6-dimethyl-4-heptanol 1.5
    DEF 4.06
    dimethyl isosorbide 11.35
    tetrachloroethylene 3.41
    eugenol 7.75
    triacetin 5.07
    span 80 6.06
    1,4-butanediol 1.72
    1,1-dichloroethane 2.13
    2-methyl-1-pentanol 2.49
    methyl formate 1.46
    2-methyl-1-butanol 2.95
    n-decane 0.1
    butyronitrile 2.11
    3,7-dimethyl-1-octanol 1.75
    1-chlorooctane 0.57
    1-chlorotetradecane 0.14
    n-nonane 0.08
    undecane 0.05
    tert-butylcyclohexane 0.16
    cyclooctane 0.08
    cyclopentanol 2.25
    tetrahydropyran 4.51
    tert-amyl methyl ether 2.36
    2,5,8-trioxanonane 9.88
    1-hexene 0.57
    2-isopropoxyethanol 5.27
    2,2,2-trifluoroethanol 1.52
    methyl butyrate 2.39

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction