Lysozyme

Overview IFRA Request a quote

  • Identifiers

    CAS number
    12650-88-3

    Molecular formula
    C99H159N37O23

    SMILES
    CCC(C)C(C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(C(C)C)C(=O)NC(C)C(=O)NC(CC3=CNC4=CC=CC=C43)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)O)NC(=O)CNC(=O)C(CCC(=O)N)NC(=O)C5CCCN5C(=O)C(CC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C(C(C)C)NC(=O)C(CCCNC(=N)N)N

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 67.23%
    Savory 42.15%
    Cooling 32.03%
    Meaty 28.1%
    Fishy 26.65%
    Cooked 20.58%
    Milky 15.51%
    Ripe 15.47%
    Animal 15.12%
    Cheesy 14.97%

     

    Flavor
    Bitter 73.81%
    Odorless 49.8%
    Bland 33.2%
    Sweet-like 20.78%
    Mild 19.77%
    Nitrile 18.71%
    Yeast 17.75%
    Cedarleaf 17.71%
    Oriental 17.47%
    Taco 17.09%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    -7.4

    pKa est.
    7.52 (neutral)

    Molecular weight
    2235.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    4123°C

    Flash point

    • 402.18 ˚C est.

  • Synonyms

    • 12650-88-3
    • LYSOZYME
    • Lysozyme (chicken egg white)
    • Delvozyme
    • Hen Muramidase
    • Lysozyme G
    • Hen Egg Lysozyme
    • Lysozyme (DCF)
    • N,ODiacetylmuramidase
    • N-ACETYLMURAMIDE GLYCANOHYDROLASE
    • NAcetylmuramyl hydrolase
    • LYSOZYME [INCI]
    • LYSOZYME [MI]
    • Mucopeptide glucohydrolase
    • RefChem:800220
    • LYSOZYME [WHO-DD]
    • Hen N-Acetylmuramyl Hydrolase
    • Lysozyme hydrochlorideMuramidase
    • NAcetylmuramide glycanohydrolase
    • 1ZML031Y3C
    • 1,4-N-ACETYLMURAMIDASE
    • N Acetylmuramide Glycanhydrolase
    • N-Acetylmuramide Glycanhydrolase
    • N-ACETYLMURAMYL HYDROLASE
    • INS NO.1105
    • Glycanhydrolase, N-Acetylmuramide
    • DTXSID901010855
    • HEN EGG LYSOZYME (REDUCED)
    • INS-1105
    • EINECS 232-620-4
    • Peptidoglycan N-acetylmuramoylhydrolase
    • E-1105
    • E.C. 3.2.1.17
    • 232-620-4
    • 235-747-3
    • 9001-63-2
    • 968JKA7T33
    • EC 235-747-3
    • EINECS 235-747-3
    • Globulin G
    • Globulin G1
    • LYSOZYME, CHICKEN EGG WHITE
    • Muramidase
    • Lysozymum
    • Lysozyme from chicken egg white
    • Lysozyme, Egg White
    • AT25331
    • DA-75223
    • SY071280
    • LYSOZYME FROM CHICKEN EGG WHITE (ENZYME ACTIVITY MIN 20000U/MG)
    • H-DL-Arg-DL-Val-DL-Val-DL-Arg-DL-Asp-DL-Pro-DL-Gln-Gly-DL-xiIle-DL-Arg-DL-Ala-DL-Trp-DL-Val-DL-Ala-DL-Trp-DL-Arg-DL-Asn-DL-Arg-OH
    • 9001-63-2

  • Applications

    Lysozyme (CAS 12650-88-3) is a muramidase enzyme that hydrolyzes peptidoglycan in bacterial cell walls and is applied across several industries as an antimicrobial or processing aid. Real-world applications include: food processing and preservation to control bacterial growth (notably in dairy products like cheese, as well as in wine and fruit juices); in biotechnology and pharmaceuticals as a lysing enzyme to release intracellular components and as a reagent in protein/DNA purification and diagnostic kits; cosmetics and personal care as an antimicrobial component or mild cleansing enzyme in certain formulations, within regulatory limits; cleaning and industrial maintenance in enzyme-based cleaners to provide antimicrobial action; and agriculture where it is evaluated as an antimicrobial for post-harvest treatment or crop protection, subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 13.33
    methanol 40.34
    isopropanol 5.34
    water 1.66
    ethyl acetate 3.69
    n-propanol 7.78
    acetone 15.34
    n-butanol 4.0
    acetonitrile 4.18
    DMF 182.86
    toluene 0.26
    isobutanol 3.08
    1,4-dioxane 15.24
    methyl acetate 9.5
    THF 31.33
    2-butanone 11.68
    n-pentanol 3.11
    sec-butanol 4.08
    n-hexane 0.1
    ethylene glycol 27.43
    NMP 183.9
    cyclohexane 0.06
    DMSO 130.09
    n-butyl acetate 2.14
    n-octanol 1.32
    chloroform 3.88
    n-propyl acetate 3.43
    acetic acid 76.18
    dichloromethane 4.47
    cyclohexanone 9.78
    propylene glycol 34.02
    isopropyl acetate 1.55
    DMAc 166.09
    2-ethoxyethanol 33.96
    isopentanol 1.7
    n-heptane 0.07
    ethyl formate 10.01
    1,2-dichloroethane 2.74
    n-hexanol 1.23
    2-methoxyethanol 83.89
    isobutyl acetate 1.24
    tetrachloromethane 0.58
    n-pentyl acetate 2.84
    transcutol 39.56
    n-heptanol 1.64
    ethylbenzene 0.21
    MIBK 1.15
    2-propoxyethanol 19.07
    tert-butanol 2.15
    MTBE 1.14
    2-butoxyethanol 16.99
    propionic acid 17.0
    o-xylene 0.2
    formic acid 127.71
    diethyl ether 1.93
    m-xylene 0.13
    p-xylene 0.39
    chlorobenzene 0.52
    dimethyl carbonate 10.59
    n-octane 0.05
    formamide 104.31
    cyclopentanone 30.21
    2-pentanone 4.64
    anisole 1.34
    cyclopentyl methyl ether 2.78
    gamma-butyrolactone 50.56
    1-methoxy-2-propanol 36.09
    pyridine 9.61
    3-pentanone 3.95
    furfural 51.48
    n-dodecane 0.03
    diethylene glycol 31.76
    diisopropyl ether 0.18
    tert-amyl alcohol 2.31
    acetylacetone 8.3
    n-hexadecane 0.03
    acetophenone 2.77
    methyl propionate 7.55
    isopentyl acetate 1.22
    trichloroethylene 6.57
    n-nonanol 1.34
    cyclohexanol 1.58
    benzyl alcohol 2.8
    2-ethylhexanol 0.48
    isooctanol 0.9
    dipropyl ether 1.18
    1,2-dichlorobenzene 0.55
    ethyl lactate 6.8
    propylene carbonate 14.08
    n-methylformamide 71.48
    2-pentanol 1.44
    n-pentane 0.07
    1-propoxy-2-propanol 9.0
    1-methoxy-2-propyl acetate 4.36
    2-(2-methoxypropoxy) propanol 10.18
    mesitylene 0.06
    ε-caprolactone 12.64
    p-cymene 0.09
    epichlorohydrin 25.88
    1,1,1-trichloroethane 0.94
    2-aminoethanol 27.31
    morpholine-4-carbaldehyde 127.19
    sulfolane 86.0
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 7.2
    n-hexyl acetate 2.72
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 18.35
    sec-butyl acetate 1.4
    tert-butyl acetate 1.03
    decalin 0.03
    glycerin 93.64
    diglyme 32.91
    acrylic acid 29.69
    isopropyl myristate 0.56
    n-butyric acid 9.98
    acetyl acetate 2.57
    di(2-ethylhexyl) phthalate 1.44
    ethyl propionate 3.01
    nitromethane 107.89
    1,2-diethoxyethane 4.28
    benzonitrile 1.62
    trioctyl phosphate 1.03
    1-bromopropane 0.89
    gamma-valerolactone 106.61
    n-decanol 0.82
    triethyl phosphate 1.33
    4-methyl-2-pentanol 0.41
    propionitrile 2.66
    vinylene carbonate 13.43
    1,1,2-trichlorotrifluoroethane 58.57
    DMS 4.38
    cumene 0.12
    2-octanol 0.97
    2-hexanone 3.97
    octyl acetate 1.32
    limonene 0.13
    1,2-dimethoxyethane 33.51
    ethyl orthosilicate 1.07
    tributyl phosphate 1.2
    diacetone alcohol 5.09
    N,N-dimethylaniline 1.13
    acrylonitrile 6.25
    aniline 1.35
    1,3-propanediol 28.46
    bromobenzene 0.34
    dibromomethane 1.68
    1,1,2,2-tetrachloroethane 5.68
    2-methyl-cyclohexyl acetate 1.12
    tetrabutyl urea 2.68
    diisobutyl methanol 0.15
    2-phenylethanol 1.54
    styrene 0.26
    dioctyl adipate 1.57
    dimethyl sulfate 25.28
    ethyl butyrate 1.83
    methyl lactate 21.69
    butyl lactate 6.92
    diethyl carbonate 1.39
    propanediol butyl ether 23.84
    triethyl orthoformate 2.08
    p-tert-butyltoluene 0.07
    methyl 4-tert-butylbenzoate 3.22
    morpholine 26.42
    tert-butylamine 0.52
    n-dodecanol 0.49
    dimethoxymethane 32.5
    ethylene carbonate 7.95
    cyrene 21.18
    2-ethoxyethyl acetate 7.22
    2-ethylhexyl acetate 1.0
    1,2,4-trichlorobenzene 1.05
    4-methylpyridine 4.65
    dibutyl ether 0.99
    2,6-dimethyl-4-heptanol 0.15
    DEF 14.58
    dimethyl isosorbide 9.78
    tetrachloroethylene 3.88
    eugenol 5.91
    triacetin 5.86
    span 80 8.7
    1,4-butanediol 11.36
    1,1-dichloroethane 1.49
    2-methyl-1-pentanol 1.59
    methyl formate 50.17
    2-methyl-1-butanol 2.34
    n-decane 0.07
    butyronitrile 1.92
    3,7-dimethyl-1-octanol 0.47
    1-chlorooctane 0.27
    1-chlorotetradecane 0.09
    n-nonane 0.06
    undecane 0.04
    tert-butylcyclohexane 0.02
    cyclooctane 0.02
    cyclopentanol 5.39
    tetrahydropyran 4.44
    tert-amyl methyl ether 1.16
    2,5,8-trioxanonane 17.97
    1-hexene 0.38
    2-isopropoxyethanol 11.25
    2,2,2-trifluoroethanol 34.82
    methyl butyrate 5.31

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction