Lysine Hydrochloride

Overview IFRA Request a quote

  • Identifiers

    CAS number
    657-27-2

    Molecular formula
    C6H15ClN2O2

    SMILES
    C(CCN)C[C@@H](C(=O)O)N.Cl

  • Odor profile

    Fragrance
    Odorless 61.87%
    Fishy 54.32%
    Savory 30.85%
    Cheesy 28.25%
    Meaty 25.9%
    Ripe 23.74%
    Cooling 22.36%
    Animal 21.76%
    Sweet 17.4%
    Oily 16.97%

     

    Flavor
    Odorless 58.52%
    Mild 35.54%
    Bland 27.75%
    Sulfury 25.09%
    Faint 24.92%
    Sulfurous 22.44%
    Sweet-like 21.5%
    Glue 20.08%
    Slightly waxy 19.98%
    Bloody 19.97%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    5.27 (weak acid)

    Molecular weight
    182.65 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    308°C

    Flash point

    • 149.69 ˚C est.

  • Synonyms

    • L-Lysine hydrochloride
    • 657-27-2
    • L-Lysine monohydrochloride
    • L-Lysine, monohydrochloride
    • lysine hydrochloride
    • L-lysine HCl
    • Lyamine
    • 10098-89-2
    • H-Lys-OH.HCl
    • L-(+)-Lysine Monohydrochloride
    • Darvyl
    • Lysion
    • Lysine HCl
    • (S)-2,6-Diaminohexanoic acid hydrochloride
    • L-Gen
    • L-Lysine monohydrocholoride
    • Lysine hcl, l-
    • Lysine monohydrochloride
    • UNII-JNJ23Q2COM
    • JNJ23Q2COM
    • NSC 9253
    • EINECS 211-519-9
    • Enisyl
    • Lysine, l-, monohydrochloride
    • CHEBI:53633
    • AI3-52405
    • (2S)-2,6-diaminohexanoic acid hydrochloride
    • NSC-9253
    • MFCD00064564
    • Lysine, monohydrochloride
    • (S)-2,6-Diaminohexanoic acid monohydrochloride
    • EC 211-519-9
    • Lysine hydrochloride [USAN:USP:JAN]
    • 28826-16-6
    • L-Lysine, hydrochloride
    • (2S)-2,6-Diaminohexanoic acid;hydrochloride
    • C6H15ClN2O2
    • LYSINE HYDROCHLORIDE (MART.)
    • LYSINE HYDROCHLORIDE [MART.]
    • MFCD00081870
    • Lysine hydrochloride (USAN:USP:JAN)
    • L-LYSINE HYDROCHLORIDE (USP-RS)
    • L-LYSINE HYDROCHLORIDE [USP-RS]
    • Lysine hydrochloride (VAN)
    • LYSINE HYDROCHLORIDE (EP MONOGRAPH)
    • LYSINE HYDROCHLORIDE [EP MONOGRAPH]
    • L-Lysine hydrochloride (VAN)
    • LYSINE HYDROCHLORIDE (USP MONOGRAPH)
    • LYSINE HYDROCHLORIDE [USP MONOGRAPH]
    • Lysine, monohydrochloride, L-
    • L-Lysine, hydrochloride (1:?)
    • l(+)-lysine monohydrochloride
    • L-Lysine, hydrochloride (1:1)
    • EINECS 233-234-9
    • VIRALYS
    • L-lysine.hydrochloride
    • H-Lys-OH⋅HCl
    • L-Lysine-Hydrochloride
    • ENISYL-F
    • nBu-PLys(100)*HCl
    • L-LysineHydrochloride>99%
    • Lysine hydrochloride (USP)
    • SCHEMBL41761
    • l(+)-lysine monohy-drochloride
    • CHEMBL2105886
    • DTXSID9029198
    • L-Lysine hydrochloride (JP17)
    • HY-N0470R
    • DTXSID10904868
    • L-Lysine hydrochloride (Standard)
    • LYSINE HYDROCHLORIDE [JAN]
    • Pharmakon1600-01301003
    • LYSINE HYDROCHLORIDE [USAN]
    • HY-N0470
    • LYSINE HYDROCHLORIDE [VANDF]
    • L-LYSINE HYDROCHLORIDE [JAN]
    • LYSINE MONOHYDROCHLORIDE [MI]
    • NSC760110
    • s3953
    • LYSINE HYDROCHLORIDE [WHO-DD]
    • AKOS015847945
    • AKOS015892881
    • CCG-214725
    • CS-7885
    • FL30554
    • NSC-760110
    • L-LYSINE MONOHYDROCHLORIDE [FCC]
    • AC-23978
    • BS-17408
    • FP171545
    • Poly-L-lysine hydrochloride - MW 3300Da
    • DB-029969
    • L-Lysine monohydrochloride, p.a., 98.5%
    • L0071
    • NS00082898
    • EN300-54534
    • L-Lysine hydrochloride, >=98%, natural, FG
    • Lysine Hydrochloride (L-Lysine Hydrochloride)
    • D02279
    • D70613
    • M03093
    • L-alpha,epsilondiaminocaproic acid monohydrochloride
    • L-Lysine monohydrochloride, BioUltra, >=99.5% (AT)
    • Q27124123
    • Z812534818
    • L-Lysine monohydrochloride, reagent grade, >=98% (HPLC)
    • L-Lysine monohydrochloride, SAJ special grade, >=99.0%
    • H-Lys-OH.HCl L-Lysine monohydrochloride (from non-animal source)
    • L-Lysine monohydrochloride, Cell Culture Reagent (H-L-Lys-OH.HCl)
    • Lysine hydrochloride, European Pharmacopoeia (EP) Reference Standard
    • L-Lysine hydrochloride, United States Pharmacopeia (USP) Reference Standard
    • L-Lysine monohydrochloride, certified reference material, TraceCERT(R)
    • L-Lysine monohydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
    • 211-519-9
    • L-Lysine monohydrochloride, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

  • Applications

    L-Lysine Hydrochloride (CAS 657-27-2) is the monohydrochloride salt of the essential amino acid lysine and is widely used as a feed additive to boost weight gain, improve protein utilization and feed conversion in livestock, poultry and aquaculture; as a nutritional and pharmaceutical ingredient that supports collagen synthesis, calcium absorption, growth promotion, immune enhancement and the prevention of lysine deficiency or herpes-related cold sores; as an intermediate in peptide synthesis, a biological buffer component, a nutrient for microbial fermentation and cell culture, and as a fortifier to raise the nutritional value of cereal products, high-protein beverages and processed foods.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.02
    methanol 0.35
    isopropanol 0.01
    water 214.45
    ethyl acetate 0.01
    n-propanol 0.01
    acetone 0.01
    n-butanol 0.01
    acetonitrile 0.01
    DMF 0.12
    toluene 0.02
    isobutanol 0.01
    1,4-dioxane 0.02
    methyl acetate 0.01
    THF 0.05
    2-butanone 0.01
    n-pentanol 0.01
    sec-butanol 0.01
    n-hexane 0.01
    ethylene glycol 4.63
    NMP 6.8
    cyclohexane 0.02
    DMSO 7.84
    n-butyl acetate 0.08
    n-octanol 0.02
    chloroform 0.02
    n-propyl acetate 0.02
    acetic acid 3.13
    dichloromethane 0.03
    cyclohexanone 0.15
    propylene glycol 0.82
    isopropyl acetate 0.02
    DMAc 0.5
    2-ethoxyethanol 0.16
    isopentanol 0.02
    n-heptane 0.02
    ethyl formate 0.05
    1,2-dichloroethane 0.02
    n-hexanol 0.05
    2-methoxyethanol 0.26
    isobutyl acetate 0.03
    tetrachloromethane 0.06
    n-pentyl acetate 0.04
    transcutol 1.03
    n-heptanol 0.05
    ethylbenzene 0.03
    MIBK 0.04
    2-propoxyethanol 0.38
    tert-butanol 0.03
    MTBE 0.01
    2-butoxyethanol 0.29
    propionic acid 0.4
    o-xylene 0.09
    formic acid 60.7
    diethyl ether 0.0
    m-xylene 0.07
    p-xylene 0.05
    chlorobenzene 0.03
    dimethyl carbonate 0.09
    n-octane 0.01
    formamide 9.44
    cyclopentanone 0.21
    2-pentanone 0.01
    anisole 0.03
    cyclopentyl methyl ether 0.05
    gamma-butyrolactone 0.59
    1-methoxy-2-propanol 0.12
    pyridine 0.05
    3-pentanone 0.02
    furfural 2.51
    n-dodecane 0.0
    diethylene glycol 3.87
    diisopropyl ether 0.01
    tert-amyl alcohol 0.04
    acetylacetone 0.15
    n-hexadecane 0.0
    acetophenone 0.16
    methyl propionate 0.03
    isopentyl acetate 0.14
    trichloroethylene 0.06
    n-nonanol 0.02
    cyclohexanol 0.06
    benzyl alcohol 0.12
    2-ethylhexanol 0.09
    isooctanol 0.07
    dipropyl ether 0.03
    1,2-dichlorobenzene 0.09
    ethyl lactate 0.3
    propylene carbonate 0.64
    n-methylformamide 0.19
    2-pentanol 0.01
    n-pentane 0.0
    1-propoxy-2-propanol 0.29
    1-methoxy-2-propyl acetate 0.36
    2-(2-methoxypropoxy) propanol 0.97
    mesitylene 0.1
    ε-caprolactone 0.23
    p-cymene 0.14
    epichlorohydrin 0.08
    1,1,1-trichloroethane 0.02
    2-aminoethanol 0.94
    morpholine-4-carbaldehyde 1.32
    sulfolane 14.34
    2,2,4-trimethylpentane 0.01
    2-methyltetrahydrofuran 0.03
    n-hexyl acetate 0.04
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 0.67
    sec-butyl acetate 0.02
    tert-butyl acetate 0.09
    decalin 0.03
    glycerin 11.93
    diglyme 0.76
    acrylic acid 1.79
    isopropyl myristate 0.03
    n-butyric acid 0.21
    acetyl acetate 0.12
    di(2-ethylhexyl) phthalate 0.34
    ethyl propionate 0.03
    nitromethane 0.59
    1,2-diethoxyethane 0.03
    benzonitrile 0.07
    trioctyl phosphate 0.17
    1-bromopropane 0.0
    gamma-valerolactone 0.61
    n-decanol 0.02
    triethyl phosphate 0.37
    4-methyl-2-pentanol 0.02
    propionitrile 0.01
    vinylene carbonate 0.52
    1,1,2-trichlorotrifluoroethane 3.48
    DMS 0.23
    cumene 0.06
    2-octanol 0.02
    2-hexanone 0.02
    octyl acetate 0.04
    limonene 0.14
    1,2-dimethoxyethane 0.07
    ethyl orthosilicate 0.31
    tributyl phosphate 0.22
    diacetone alcohol 0.45
    N,N-dimethylaniline 0.09
    acrylonitrile 0.03
    aniline 0.06
    1,3-propanediol 0.29
    bromobenzene 0.03
    dibromomethane 0.02
    1,1,2,2-tetrachloroethane 0.07
    2-methyl-cyclohexyl acetate 0.29
    tetrabutyl urea 0.26
    diisobutyl methanol 0.11
    2-phenylethanol 0.24
    styrene 0.02
    dioctyl adipate 0.1
    dimethyl sulfate 1.3
    ethyl butyrate 0.09
    methyl lactate 0.65
    butyl lactate 0.37
    diethyl carbonate 0.12
    propanediol butyl ether 0.62
    triethyl orthoformate 0.18
    p-tert-butyltoluene 0.15
    methyl 4-tert-butylbenzoate 0.78
    morpholine 0.02
    tert-butylamine 0.01
    n-dodecanol 0.02
    dimethoxymethane 0.04
    ethylene carbonate 0.27
    cyrene 4.01
    2-ethoxyethyl acetate 0.1
    2-ethylhexyl acetate 0.12
    1,2,4-trichlorobenzene 0.13
    4-methylpyridine 0.03
    dibutyl ether 0.01
    2,6-dimethyl-4-heptanol 0.11
    DEF 0.06
    dimethyl isosorbide 2.91
    tetrachloroethylene 0.2
    eugenol 0.86
    triacetin 0.35
    span 80 1.04
    1,4-butanediol 0.23
    1,1-dichloroethane 0.0
    2-methyl-1-pentanol 0.03
    methyl formate 0.22
    2-methyl-1-butanol 0.02
    n-decane 0.01
    butyronitrile 0.01
    3,7-dimethyl-1-octanol 0.04
    1-chlorooctane 0.01
    1-chlorotetradecane 0.01
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.02
    cyclooctane 0.02
    cyclopentanol 0.08
    tetrahydropyran 0.01
    tert-amyl methyl ether 0.02
    2,5,8-trioxanonane 1.32
    1-hexene 0.01
    2-isopropoxyethanol 0.1
    2,2,2-trifluoroethanol 4.63
    methyl butyrate 0.04

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction