Lipoprotein Lipase

Overview IFRA Request a quote

  • Identifiers

    CAS number
    9004-02-8

    Molecular formula
    C137H203Br2Cl2F3O24S8

    SMILES
    CC(C)CC(CCCCS(=O)(=O)O)C=CC1=CC=C(C=C1)F.CC(C)CC(CCCCS(=O)(=O)O)C=CC1=CC=C(C=C1)F.CC(C)CC(CCCCS(=O)(=O)O)C=CC1=CC=C(C=C1)Cl.CC(C)CC(CCCCS(=O)(=O)O)C=CC1=CC=C(C=C1)Cl.CC(C)CC(CCCCS(=O)(=O)O)C=CC1=CC=C(C=C1)Br.CC(C)C(CCCCS(=O)(=O)O)C=CC1=CC=C(C=C1)C(C)(C)C.CC(C)C(CCCCS(=O)(=O)O)C=CC1=CC=C(C=C1)F.CC(C)C(CCCCS(=O)(=O)O)C=CC1=CC=C(C=C1)Br

    Safety labels

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 42.34%
    Fatty 27.16%
    Citrus 25.22%
    Fresh 24.33%
    Savory 23.47%
    Green 21.27%
    Meaty 21.07%
    Animal 19.38%
    Waxy 18.1%
    Cooked 18.02%

     

    Flavor
    Bitter 44.57%
    Mild 20.25%
    Nitrile 20.09%
    Herbal 19.91%
    Oriental 19.56%
    Bland 19.31%
    Odorless 19.24%
    Cedarleaf 19.13%
    Butyric 18.83%
    Diterpene 18.82%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    8.08 (weak base)

    Molecular weight
    2778.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    515°C

    Flash point

    • 203.14 ˚C est.

  • Synonyms

    • 9004-02-8
    • Lipoprotein lipase
    • Lipase, lipoprotein
    • diglyceride lipase
    • Phospholipase A1
    • Postheparin Lipase
    • Lipase, Diglyceride
    • Lipase, Postheparin
    • Post Heparin Lipase
    • Post-Heparin Lipase
    • Diacylglycerol Lipase
    • Lipase, Post-Heparin
    • Lipase, Diacylglycerol
    • Heparin Clearing Factor
    • Heparin-Clearing Factor
    • Lipemia Clearing Factor
    • Lipemia-Clearing Factor
    • Factor, Heparin-Clearing
    • Factor, Lipemia-Clearing
    • RefChem:799321
    • Postheparin Lipoprotein Lipase
    • Lipase, Postheparin Lipoprotein
    • Lipoprotein Lipase, Postheparin
    • DTXSID301056897
    • DTXSID701010897
    • G47TQ855G8
    • Triacylglycero-protein acylhydrolase
    • EINECS 232-669-1
    • 232-669-1
    • 618-552-1
    • 9043-29-2
    • 931-739-5
    • clearing factor lipase
    • 1080492-01-8
    • 956594-02-8
    • 9043-29-2

  • Applications

    Lipoprotein Lipase (CAS 9004-02-8) is an enzyme that hydrolyzes triglycerides within lipoproteins, and is primarily used as a biochemical reagent in lipid research to analyze lipase activity and lipid metabolism. In biochemical labs, LPL supports in vitro assays to quantify lipase activity and to study substrate specificity and kinetic aspects of the reaction, aiding fundamental research into mechanisms and models of lipoprotein-related processes. It is also used in diagnostic research and assay development related to lipid processing and lipoprotein metabolism at the in vitro level. Additionally, LPL can be employed in biotechnology research for kinetic characterization and optimization of reaction conditions, as well as in educational and research kits to demonstrate the molecular basis of triglyceride hydrolysis in lipoproteins. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 95.66
    methanol 85.2
    isopropanol 56.09
    water 0.02
    ethyl acetate 48.37
    n-propanol 63.42
    acetone 139.24
    n-butanol 50.21
    acetonitrile 31.83
    DMF 178.41
    toluene 16.38
    isobutanol 34.56
    1,4-dioxane 56.81
    methyl acetate 41.96
    THF 227.31
    2-butanone 101.16
    n-pentanol 45.0
    sec-butanol 48.3
    n-hexane 0.74
    ethylene glycol 7.33
    NMP 117.29
    cyclohexane 1.2
    DMSO 209.31
    n-butyl acetate 40.81
    n-octanol 18.02
    chloroform 71.59
    n-propyl acetate 44.23
    acetic acid 49.61
    dichloromethane 57.47
    cyclohexanone 109.09
    propylene glycol 33.41
    isopropyl acetate 45.71
    DMAc 222.32
    2-ethoxyethanol 110.42
    isopentanol 44.98
    n-heptane 0.77
    ethyl formate 28.72
    1,2-dichloroethane 49.61
    n-hexanol 38.6
    2-methoxyethanol 159.38
    isobutyl acetate 27.06
    tetrachloromethane 3.64
    n-pentyl acetate 31.44
    transcutol 404.89
    n-heptanol 20.75
    ethylbenzene 11.4
    MIBK 64.77
    2-propoxyethanol 112.04
    tert-butanol 54.54
    MTBE 39.59
    2-butoxyethanol 61.75
    propionic acid 28.43
    o-xylene 12.79
    formic acid 20.37
    diethyl ether 32.07
    m-xylene 16.19
    p-xylene 11.22
    chlorobenzene 17.99
    dimethyl carbonate 19.0
    n-octane 0.49
    formamide 46.15
    cyclopentanone 147.97
    2-pentanone 96.69
    anisole 43.33
    cyclopentyl methyl ether 56.04
    gamma-butyrolactone 104.04
    1-methoxy-2-propanol 151.88
    pyridine 54.54
    3-pentanone 52.02
    furfural 93.48
    n-dodecane 0.52
    diethylene glycol 78.92
    diisopropyl ether 10.14
    tert-amyl alcohol 51.22
    acetylacetone 116.86
    n-hexadecane 0.61
    acetophenone 49.41
    methyl propionate 45.65
    isopentyl acetate 41.84
    trichloroethylene 102.17
    n-nonanol 17.24
    cyclohexanol 33.53
    benzyl alcohol 43.54
    2-ethylhexanol 19.81
    isooctanol 17.6
    dipropyl ether 16.91
    1,2-dichlorobenzene 18.48
    ethyl lactate 35.59
    propylene carbonate 52.08
    n-methylformamide 61.94
    2-pentanol 31.93
    n-pentane 0.82
    1-propoxy-2-propanol 78.81
    1-methoxy-2-propyl acetate 80.22
    2-(2-methoxypropoxy) propanol 83.33
    mesitylene 9.32
    ε-caprolactone 81.94
    p-cymene 9.63
    epichlorohydrin 144.62
    1,1,1-trichloroethane 28.54
    2-aminoethanol 37.57
    morpholine-4-carbaldehyde 139.47
    sulfolane 127.1
    2,2,4-trimethylpentane 1.14
    2-methyltetrahydrofuran 88.4
    n-hexyl acetate 40.85
    isooctane 1.05
    2-(2-butoxyethoxy)ethanol 117.38
    sec-butyl acetate 33.8
    tert-butyl acetate 61.51
    decalin 1.37
    glycerin 40.02
    diglyme 169.03
    acrylic acid 22.3
    isopropyl myristate 15.31
    n-butyric acid 52.51
    acetyl acetate 31.36
    di(2-ethylhexyl) phthalate 22.89
    ethyl propionate 33.46
    nitromethane 100.8
    1,2-diethoxyethane 71.08
    benzonitrile 32.48
    trioctyl phosphate 13.75
    1-bromopropane 21.79
    gamma-valerolactone 190.21
    n-decanol 12.63
    triethyl phosphate 17.99
    4-methyl-2-pentanol 22.78
    propionitrile 26.41
    vinylene carbonate 37.86
    1,1,2-trichlorotrifluoroethane 99.03
    DMS 32.27
    cumene 8.8
    2-octanol 13.04
    2-hexanone 56.53
    octyl acetate 21.23
    limonene 13.55
    1,2-dimethoxyethane 126.97
    ethyl orthosilicate 17.87
    tributyl phosphate 16.96
    diacetone alcohol 109.82
    N,N-dimethylaniline 31.85
    acrylonitrile 31.63
    aniline 29.83
    1,3-propanediol 56.27
    bromobenzene 15.64
    dibromomethane 34.31
    1,1,2,2-tetrachloroethane 87.57
    2-methyl-cyclohexyl acetate 36.41
    tetrabutyl urea 29.12
    diisobutyl methanol 12.6
    2-phenylethanol 44.78
    styrene 13.02
    dioctyl adipate 31.12
    dimethyl sulfate 35.9
    ethyl butyrate 32.38
    methyl lactate 47.8
    butyl lactate 42.63
    diethyl carbonate 20.09
    propanediol butyl ether 75.46
    triethyl orthoformate 25.44
    p-tert-butyltoluene 9.16
    methyl 4-tert-butylbenzoate 52.79
    morpholine 110.75
    tert-butylamine 22.83
    n-dodecanol 8.69
    dimethoxymethane 119.64
    ethylene carbonate 30.29
    cyrene 75.01
    2-ethoxyethyl acetate 62.75
    2-ethylhexyl acetate 29.44
    1,2,4-trichlorobenzene 25.72
    4-methylpyridine 59.08
    dibutyl ether 16.2
    2,6-dimethyl-4-heptanol 12.6
    DEF 81.65
    dimethyl isosorbide 121.38
    tetrachloroethylene 37.88
    eugenol 56.1
    triacetin 55.95
    span 80 59.64
    1,4-butanediol 22.79
    1,1-dichloroethane 40.51
    2-methyl-1-pentanol 41.93
    methyl formate 35.95
    2-methyl-1-butanol 41.31
    n-decane 0.93
    butyronitrile 36.54
    3,7-dimethyl-1-octanol 21.02
    1-chlorooctane 6.82
    1-chlorotetradecane 2.47
    n-nonane 0.78
    undecane 0.67
    tert-butylcyclohexane 1.29
    cyclooctane 0.51
    cyclopentanol 41.02
    tetrahydropyran 59.57
    tert-amyl methyl ether 34.51
    2,5,8-trioxanonane 130.39
    1-hexene 6.36
    2-isopropoxyethanol 75.0
    2,2,2-trifluoroethanol 14.37
    methyl butyrate 47.22

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction