Lauroyl Lysine

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  • Identifiers

    CAS number
    52315-75-0

    Molecular formula
    C18H36N2O3

    SMILES
    CCCCCCCCCCCC(=O)NCCCC[C@@H](C(=O)O)N

    Safety labels

  • Odor profile

    Fragrance
    Odorless 40.28%
    Savory 39.49%
    Meaty 35.36%
    Cooling 34.58%
    Fishy 32.32%
    Herbal 23.97%
    Animal 23.93%
    Oily 23.47%
    Mint 22.11%
    Fresh 21.79%

     

    Flavor
    Odorless 44.67%
    Bland 36.27%
    Mild 33.44%
    Faint 25.44%
    Slightly waxy 21.56%
    Bay oil 20.81%
    Fatty 20.47%
    Cultured dairy 20.04%
    Sweet-like 19.87%
    Delicate 19.79%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    7.0 (neutral)

    Molecular weight
    328.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    482°C

    Flash point

    • 219.44 ˚C est.

  • Synonyms

    • Lauroyl lysine
    • L-Lysine, N6-(1-oxododecyl)-
    • N6-Lauroyl-L-lysine
    • lauroyllysine
    • (2S)-2-amino-6-(dodecanoylamino)hexanoic acid
    • N6-(1-Oxododecyl)-L-lysine
    • ORISTAR LOL
    • AMIHOPE LL
    • FAMEX L 12
    • CORUM 5105
    • 113171Q70B
    • DTXSID80885998
    • LYSINE, N6-LAUROYL-, L-
    • EINECS 257-843-4
    • RefChem:798579
    • LAUROYL LYSINE [INCI]
    • DTXCID901025349
    • 52315-75-0
    • n6-dodecanoyl-l-lysine
    • (S)-2-Amino-6-dodecanamidohexanoic acid
    • Nepsilon-Lauroyl-L-Lysine
    • MFCD09954506
    • H-L-Lys(lauroyl)-OH
    • N~6~-Dodecanoyl-L-lysine
    • SCHEMBL308741
    • UNII-113171Q70B
    • N-.EPSILON.-LAUROYL-L-LYSINE
    • AKOS030228095
    • SY107785
    • CS-0064252
    • NS00013826
    • E78661
    • 315O750
    • F603528
    • Q27251234
    • 52315-75-0

  • Applications

    Lauroyl Lysine (CAS 52315-75-0) is widely used in cosmetics and personal care as a mild surfactant and conditioning agent, helping stabilize emulsions, improve skin feel, and act as an emollient in creams, lotions, cleansers, and hair-care formulations; it is also used as an excipient in topical pharmaceutical formulations to enhance spreadability and texture; in household cleaning products it functions as a surfactant and conditioning aid providing mild cleansing; in coatings and inks it can serve as a surface-active agent or pigment dispersant to improve wetting and dispersion.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 15.76
    methanol 54.03
    isopropanol 6.88
    water 0.58
    ethyl acetate 5.31
    n-propanol 10.35
    acetone 10.63
    n-butanol 8.68
    acetonitrile 2.4
    DMF 36.92
    toluene 2.67
    isobutanol 7.35
    1,4-dioxane 13.8
    methyl acetate 4.44
    THF 46.8
    2-butanone 8.11
    n-pentanol 11.04
    sec-butanol 6.73
    n-hexane 0.39
    ethylene glycol 5.49
    NMP 91.9
    cyclohexane 0.81
    DMSO 164.46
    n-butyl acetate 8.36
    n-octanol 6.52
    chloroform 12.61
    n-propyl acetate 10.09
    acetic acid 39.71
    dichloromethane 11.69
    cyclohexanone 42.74
    propylene glycol 11.5
    isopropyl acetate 7.9
    DMAc 85.37
    2-ethoxyethanol 42.67
    isopentanol 10.81
    n-heptane 0.32
    ethyl formate 8.75
    1,2-dichloroethane 9.77
    n-hexanol 7.27
    2-methoxyethanol 48.41
    isobutyl acetate 8.18
    tetrachloromethane 3.15
    n-pentyl acetate 12.51
    transcutol 133.8
    n-heptanol 8.66
    ethylbenzene 2.73
    MIBK 10.08
    2-propoxyethanol 30.33
    tert-butanol 11.27
    MTBE 5.19
    2-butoxyethanol 32.39
    propionic acid 15.48
    o-xylene 4.24
    formic acid 35.95
    diethyl ether 1.94
    m-xylene 3.43
    p-xylene 4.06
    chlorobenzene 4.5
    dimethyl carbonate 4.79
    n-octane 0.3
    formamide 39.25
    cyclopentanone 46.75
    2-pentanone 8.79
    anisole 6.52
    cyclopentyl methyl ether 14.28
    gamma-butyrolactone 48.74
    1-methoxy-2-propanol 34.22
    pyridine 12.82
    3-pentanone 6.46
    furfural 50.42
    n-dodecane 0.23
    diethylene glycol 28.25
    diisopropyl ether 1.63
    tert-amyl alcohol 11.99
    acetylacetone 21.45
    n-hexadecane 0.26
    acetophenone 14.35
    methyl propionate 6.13
    isopentyl acetate 11.44
    trichloroethylene 20.84
    n-nonanol 6.75
    cyclohexanol 14.52
    benzyl alcohol 12.26
    2-ethylhexanol 5.17
    isooctanol 7.92
    dipropyl ether 3.29
    1,2-dichlorobenzene 6.62
    ethyl lactate 12.62
    propylene carbonate 26.94
    n-methylformamide 20.35
    2-pentanol 4.47
    n-pentane 0.22
    1-propoxy-2-propanol 21.15
    1-methoxy-2-propyl acetate 19.02
    2-(2-methoxypropoxy) propanol 28.01
    mesitylene 2.82
    ε-caprolactone 39.51
    p-cymene 2.73
    epichlorohydrin 32.41
    1,1,1-trichloroethane 7.14
    2-aminoethanol 16.69
    morpholine-4-carbaldehyde 60.69
    sulfolane 126.55
    2,2,4-trimethylpentane 0.49
    2-methyltetrahydrofuran 19.07
    n-hexyl acetate 13.19
    isooctane 0.28
    2-(2-butoxyethoxy)ethanol 43.82
    sec-butyl acetate 7.81
    tert-butyl acetate 14.03
    decalin 0.87
    glycerin 29.61
    diglyme 74.47
    acrylic acid 16.65
    isopropyl myristate 4.24
    n-butyric acid 26.64
    acetyl acetate 7.84
    di(2-ethylhexyl) phthalate 9.61
    ethyl propionate 6.93
    nitromethane 34.44
    1,2-diethoxyethane 14.99
    benzonitrile 8.04
    trioctyl phosphate 6.57
    1-bromopropane 2.83
    gamma-valerolactone 91.07
    n-decanol 4.38
    triethyl phosphate 7.83
    4-methyl-2-pentanol 5.19
    propionitrile 2.7
    vinylene carbonate 19.45
    1,1,2-trichlorotrifluoroethane 61.92
    DMS 10.71
    cumene 2.95
    2-octanol 5.15
    2-hexanone 10.67
    octyl acetate 6.24
    limonene 3.78
    1,2-dimethoxyethane 40.62
    ethyl orthosilicate 8.29
    tributyl phosphate 7.58
    diacetone alcohol 30.47
    N,N-dimethylaniline 7.69
    acrylonitrile 4.5
    aniline 7.06
    1,3-propanediol 25.64
    bromobenzene 3.85
    dibromomethane 6.65
    1,1,2,2-tetrachloroethane 23.29
    2-methyl-cyclohexyl acetate 12.72
    tetrabutyl urea 11.89
    diisobutyl methanol 3.75
    2-phenylethanol 10.57
    styrene 2.71
    dioctyl adipate 10.58
    dimethyl sulfate 18.13
    ethyl butyrate 8.1
    methyl lactate 15.14
    butyl lactate 21.0
    diethyl carbonate 5.29
    propanediol butyl ether 34.47
    triethyl orthoformate 9.56
    p-tert-butyltoluene 2.82
    methyl 4-tert-butylbenzoate 23.57
    morpholine 25.02
    tert-butylamine 4.1
    n-dodecanol 2.9
    dimethoxymethane 16.66
    ethylene carbonate 16.51
    cyrene 40.3
    2-ethoxyethyl acetate 21.04
    2-ethylhexyl acetate 8.28
    1,2,4-trichlorobenzene 9.44
    4-methylpyridine 10.44
    dibutyl ether 4.31
    2,6-dimethyl-4-heptanol 3.75
    DEF 18.48
    dimethyl isosorbide 49.09
    tetrachloroethylene 19.73
    eugenol 24.66
    triacetin 23.72
    span 80 25.25
    1,4-butanediol 12.89
    1,1-dichloroethane 4.85
    2-methyl-1-pentanol 12.36
    methyl formate 12.48
    2-methyl-1-butanol 9.83
    n-decane 0.43
    butyronitrile 4.08
    3,7-dimethyl-1-octanol 6.16
    1-chlorooctane 2.27
    1-chlorotetradecane 0.82
    n-nonane 0.36
    undecane 0.3
    tert-butylcyclohexane 0.68
    cyclooctane 0.36
    cyclopentanol 16.73
    tetrahydropyran 11.05
    tert-amyl methyl ether 6.09
    2,5,8-trioxanonane 48.14
    1-hexene 1.48
    2-isopropoxyethanol 26.37
    2,2,2-trifluoroethanol 19.43
    methyl butyrate 12.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction