Lauroyl Glutamic Acid

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  • Identifiers

    CAS number
    3397-65-7

    Molecular formula
    C17H31NO5

    SMILES
    CCCCCCCCCCCC(=O)N[C@@H](CCC(=O)O)C(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Odorless 48.63%
    Savory 38.11%
    Meaty 31.2%
    Fatty 30.14%
    Milky 26.89%
    Oily 23.32%
    Cooling 23.12%
    Lactonic 22.68%
    Waxy 21.79%
    Peach 20.62%

     

    Flavor
    Odorless 52.68%
    Mild 36.15%
    Bland 35.66%
    Fatty 26.26%
    Faint 23.92%
    Bay oil 21.77%
    Waxy 21.69%
    Slightly waxy 21.25%
    Cultured dairy 21.17%
    Sweet-like 20.99%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.2

    pKa est.
    5.55 (weak acid)

    Molecular weight
    329.4 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    455°C

    Flash point

    • 252.55 ˚C est.

  • Synonyms

    • N-Lauroyl-L-glutamic acid
    • 3397-65-7
    • lauroyl glutamic acid
    • L-Glutamic acid, N-(1-oxododecyl)-
    • lauroylglutamic acid
    • N-(1-Oxododecyl)-L-glutamic acid
    • AMISOFT LA
    • EINECS 222-261-1
    • DTXSID7074820
    • GLUTAMIC ACID, N-LAUROYL-
    • NSC 522180
    • NSC-522180
    • GLUTAMIC ACID, N-LAUROYL-, L-
    • LAUROYL GLUTAMIC ACID [WHO-DD]
    • RefChem:798577
    • DTXCID8038770
    • LAUROYL GLUTAMIC ACID [INCI]
    • N-Lauroylglutamic acid
    • N-Dodecanoyl-L-glutamic acid
    • C17H31NO5
    • (2S)-2-(dodecanoylamino)pentanedioic acid
    • MFCD06410798
    • Dodecanoyl-L-glutamic acid
    • N-Dodecanoylglutamic acid
    • Sodium N-dodecanoyl-L-glutamate
    • MT62245356
    • SDGlu
    • N-Lauroyl-L-glutamic Acid (>80%)
    • (S)-2-DODECANAMIDOPENTANEDIOIC ACID
    • UNII-MT62245356
    • N-dodecanoyl-l-glu
    • lauroyl-L-glutamic acid
    • SCHEMBL55274
    • Nalpha-lauroyl-L-glutamic acid
    • orb1306691
    • AKOS015839845
    • AKOS015901453
    • DL-Glutamic acid, N-(1-oxododecyl)-
    • FL29887
    • DS-16193
    • CS-0111611
    • NS00003274
    • C74746
    • Q27284219
    • 3397-65-7

  • Applications

    Lauroyl Glutamic Acid (CAS 3397-65-7) is an amino-acid-derived surfactant commonly used in cosmetic and personal care formulations as a mild cleansing and emulsifying agent, and it also serves as a conditioning ingredient in shampoos and facial cleansers, contributing to foam stability and skin tolerance. It is also employed in household and industrial cleaning products as a biodegradable surfactant and foam booster, aiding oil-in-water emulsions and fragrance retention. In polymer and plastics applications, it can act as a compatibilizer or intermediate for the synthesis of other surfactants, while coatings and inks may utilize it as a surfactant additive to improve wetting and dispersion. In agricultural formulations, it may serve as a wetting agent or spreading adjuvant to enhance pesticide or fungicide performance. Subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 30.49
    methanol 81.73
    isopropanol 15.17
    water 0.66
    ethyl acetate 10.05
    n-propanol 19.35
    acetone 31.38
    n-butanol 12.6
    acetonitrile 4.56
    DMF 294.14
    toluene 2.51
    isobutanol 11.35
    1,4-dioxane 20.42
    methyl acetate 11.92
    THF 67.84
    2-butanone 18.07
    n-pentanol 15.39
    sec-butanol 13.06
    n-hexane 0.59
    ethylene glycol 13.22
    NMP 279.33
    cyclohexane 0.48
    DMSO 500.68
    n-butyl acetate 11.12
    n-octanol 6.78
    chloroform 8.1
    n-propyl acetate 12.93
    acetic acid 62.55
    dichloromethane 9.69
    cyclohexanone 49.77
    propylene glycol 26.03
    isopropyl acetate 12.26
    DMAc 396.86
    2-ethoxyethanol 67.82
    isopentanol 13.41
    n-heptane 0.29
    ethyl formate 12.51
    1,2-dichloroethane 10.99
    n-hexanol 8.3
    2-methoxyethanol 92.7
    isobutyl acetate 8.35
    tetrachloromethane 2.0
    n-pentyl acetate 12.94
    transcutol 165.6
    n-heptanol 7.78
    ethylbenzene 3.35
    MIBK 14.14
    2-propoxyethanol 43.94
    tert-butanol 24.36
    MTBE 10.02
    2-butoxyethanol 33.79
    propionic acid 29.76
    o-xylene 5.08
    formic acid 62.15
    diethyl ether 4.53
    m-xylene 3.45
    p-xylene 4.91
    chlorobenzene 3.77
    dimethyl carbonate 13.7
    n-octane 0.27
    formamide 90.05
    cyclopentanone 70.77
    2-pentanone 15.82
    anisole 10.35
    cyclopentyl methyl ether 18.61
    gamma-butyrolactone 83.29
    1-methoxy-2-propanol 70.08
    pyridine 16.65
    3-pentanone 12.21
    furfural 69.92
    n-dodecane 0.22
    diethylene glycol 44.84
    diisopropyl ether 2.31
    tert-amyl alcohol 23.55
    acetylacetone 38.17
    n-hexadecane 0.24
    acetophenone 20.79
    methyl propionate 15.53
    isopentyl acetate 13.49
    trichloroethylene 19.43
    n-nonanol 6.99
    cyclohexanol 14.33
    benzyl alcohol 16.0
    2-ethylhexanol 5.03
    isooctanol 6.94
    dipropyl ether 4.34
    1,2-dichlorobenzene 6.09
    ethyl lactate 18.38
    propylene carbonate 38.21
    n-methylformamide 67.32
    2-pentanol 7.34
    n-pentane 0.29
    1-propoxy-2-propanol 28.59
    1-methoxy-2-propyl acetate 26.14
    2-(2-methoxypropoxy) propanol 43.39
    mesitylene 2.77
    ε-caprolactone 51.84
    p-cymene 2.75
    epichlorohydrin 49.12
    1,1,1-trichloroethane 7.0
    2-aminoethanol 34.25
    morpholine-4-carbaldehyde 157.24
    sulfolane 235.18
    2,2,4-trimethylpentane 0.55
    2-methyltetrahydrofuran 25.9
    n-hexyl acetate 15.88
    isooctane 0.29
    2-(2-butoxyethoxy)ethanol 56.97
    sec-butyl acetate 9.86
    tert-butyl acetate 20.13
    decalin 0.83
    glycerin 53.83
    diglyme 99.59
    acrylic acid 32.02
    isopropyl myristate 5.58
    n-butyric acid 31.22
    acetyl acetate 11.28
    di(2-ethylhexyl) phthalate 11.78
    ethyl propionate 11.49
    nitromethane 80.82
    1,2-diethoxyethane 20.93
    benzonitrile 9.33
    trioctyl phosphate 7.4
    1-bromopropane 3.5
    gamma-valerolactone 139.18
    n-decanol 4.7
    triethyl phosphate 10.5
    4-methyl-2-pentanol 6.25
    propionitrile 4.62
    vinylene carbonate 29.14
    1,1,2-trichlorotrifluoroethane 85.19
    DMS 18.36
    cumene 3.43
    2-octanol 4.98
    2-hexanone 15.97
    octyl acetate 8.26
    limonene 3.81
    1,2-dimethoxyethane 81.59
    ethyl orthosilicate 10.28
    tributyl phosphate 9.93
    diacetone alcohol 49.7
    N,N-dimethylaniline 13.81
    acrylonitrile 8.41
    aniline 7.73
    1,3-propanediol 37.67
    bromobenzene 3.22
    dibromomethane 5.36
    1,1,2,2-tetrachloroethane 22.96
    2-methyl-cyclohexyl acetate 13.97
    tetrabutyl urea 17.61
    diisobutyl methanol 3.99
    2-phenylethanol 11.41
    styrene 3.43
    dioctyl adipate 14.13
    dimethyl sulfate 55.8
    ethyl butyrate 10.13
    methyl lactate 31.54
    butyl lactate 23.39
    diethyl carbonate 7.08
    propanediol butyl ether 40.08
    triethyl orthoformate 10.8
    p-tert-butyltoluene 2.86
    methyl 4-tert-butylbenzoate 32.82
    morpholine 42.57
    tert-butylamine 8.22
    n-dodecanol 3.17
    dimethoxymethane 55.48
    ethylene carbonate 21.53
    cyrene 58.14
    2-ethoxyethyl acetate 25.19
    2-ethylhexyl acetate 9.41
    1,2,4-trichlorobenzene 9.19
    4-methylpyridine 17.33
    dibutyl ether 5.52
    2,6-dimethyl-4-heptanol 3.99
    DEF 46.38
    dimethyl isosorbide 72.83
    tetrachloroethylene 14.9
    eugenol 31.74
    triacetin 32.41
    span 80 32.1
    1,4-butanediol 20.53
    1,1-dichloroethane 5.57
    2-methyl-1-pentanol 16.01
    methyl formate 36.29
    2-methyl-1-butanol 14.07
    n-decane 0.42
    butyronitrile 5.58
    3,7-dimethyl-1-octanol 6.84
    1-chlorooctane 2.23
    1-chlorotetradecane 0.85
    n-nonane 0.36
    undecane 0.28
    tert-butylcyclohexane 0.72
    cyclooctane 0.25
    cyclopentanol 21.25
    tetrahydropyran 12.08
    tert-amyl methyl ether 12.17
    2,5,8-trioxanonane 74.1
    1-hexene 2.44
    2-isopropoxyethanol 38.85
    2,2,2-trifluoroethanol 29.12
    methyl butyrate 20.46

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction