Laureth-12

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  • Identifiers

    CAS number
    3056-00-6

    Molecular formula
    C36H74O13

    SMILES
    CCCCCCCCCCCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 37.3%
    Alcoholic 35.61%
    Fresh 21.69%
    Oily 20.56%
    Ethereal 19.98%
    Waxy 19.23%
    Sweet 18.65%
    Fishy 18.48%
    Clean 15.93%
    Fruity 14.33%

     

    Flavor
    Sweet 34.27%
    Fatty 32.04%
    Waxy 31.93%
    Mushroom 27.31%
    Earthy 26.98%
    Green 26.2%
    Oily 26.07%
    Musty 25.74%
    Vegetable 25.39%
    Odorless 25.0%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    3.5

    pKa est.
    5.05 (weak acid)

    Molecular weight
    715.0 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1480°C

    Flash point

    • 284.51 ˚C est.

  • Synonyms

    • Laureth-12
    • PEG-12 Lauryl ether
    • EINECS 221-286-5
    • DTXSID50184647
    • RefChem:7669
    • LIPOCOL L-12
    • DTXCID90107138
    • OAH19558U1
    • DODECAETHYLENE MONODODECYL ETHER
    • DODECAETHYLENEGLYCOL DODECYL ETHER
    • ETHANOL, 2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(2-(DODECYLOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)-
    • 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaoctatetracontan-1-ol
    • 3056-00-6
    • 2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-dodecoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol
    • Polidocanol Impurity 5
    • SCHEMBL8820699
    • WMPGRAUYWYBJKX-UHFFFAOYSA-N
    • dodeca-ethylene glycol monododecyl ether
    • Polidocanol Impurity 3 (Polidocanol E12)
    • NS00013824
    • 3056-00-6

  • Applications

    Laureth-12, CAS 3056-00-6, is a nonionic surfactant based on lauryl alcohol that has been ethoxylated with 12 ethylene oxide units, widely used as an emulsifier and surface-active agent in a range of formulations. Practical applications include: as an emulsifier/solubilizer in cosmetics and personal care (lotions, shampoos, body washes); as a surfactant in household cleaning products (detergents, multi-purpose cleaners); as a surface-active component in industrial coatings, inks, and adhesives; as a solubilizer for fragrances and essential oils in personal care and cleaning products; as an emulsifier and processing aid in polymers/plastics formulations; and as an adjuvant in agrochemical formulations to improve spreading and wetting.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.93
    methanol 1.67
    isopropanol 0.62
    water 0.15
    ethyl acetate 10.2
    n-propanol 1.49
    acetone 6.12
    n-butanol 1.28
    acetonitrile 2.88
    DMF 22.5
    toluene 6.36
    isobutanol 1.16
    1,4-dioxane 12.48
    methyl acetate 9.31
    THF 23.51
    2-butanone 9.68
    n-pentanol 1.35
    sec-butanol 1.52
    n-hexane 0.6
    ethylene glycol 0.6
    NMP 109.42
    cyclohexane 2.54
    DMSO 39.77
    n-butyl acetate 7.34
    n-octanol 2.19
    chloroform 43.18
    n-propyl acetate 8.26
    acetic acid 11.26
    dichloromethane 50.86
    cyclohexanone 29.29
    propylene glycol 0.88
    isopropyl acetate 6.72
    DMAc 57.28
    2-ethoxyethanol 6.27
    isopentanol 1.25
    n-heptane 1.07
    ethyl formate 7.07
    1,2-dichloroethane 23.35
    n-hexanol 1.08
    2-methoxyethanol 6.26
    isobutyl acetate 4.17
    tetrachloromethane 8.8
    n-pentyl acetate 10.22
    transcutol 29.7
    n-heptanol 1.85
    ethylbenzene 3.49
    MIBK 4.27
    2-propoxyethanol 5.45
    tert-butanol 0.96
    MTBE 3.09
    2-butoxyethanol 7.12
    propionic acid 7.67
    o-xylene 6.49
    formic acid 5.87
    diethyl ether 3.34
    m-xylene 4.23
    p-xylene 4.02
    chlorobenzene 10.07
    dimethyl carbonate 8.75
    n-octane 0.57
    formamide 9.77
    cyclopentanone 36.08
    2-pentanone 7.16
    anisole 6.75
    cyclopentyl methyl ether 16.24
    gamma-butyrolactone 48.27
    1-methoxy-2-propanol 5.09
    pyridine 18.74
    3-pentanone 11.3
    furfural 46.67
    n-dodecane 0.34
    diethylene glycol 2.99
    diisopropyl ether 1.5
    tert-amyl alcohol 2.5
    acetylacetone 15.34
    n-hexadecane 0.41
    acetophenone 13.51
    methyl propionate 12.08
    isopentyl acetate 6.27
    trichloroethylene 58.99
    n-nonanol 2.5
    cyclohexanol 4.5
    benzyl alcohol 5.04
    2-ethylhexanol 1.83
    isooctanol 1.83
    dipropyl ether 5.12
    1,2-dichlorobenzene 15.34
    ethyl lactate 7.12
    propylene carbonate 24.38
    n-methylformamide 9.73
    2-pentanol 1.13
    n-pentane 0.46
    1-propoxy-2-propanol 5.82
    1-methoxy-2-propyl acetate 11.83
    2-(2-methoxypropoxy) propanol 11.1
    mesitylene 2.84
    ε-caprolactone 34.53
    p-cymene 3.14
    epichlorohydrin 39.41
    1,1,1-trichloroethane 20.74
    2-aminoethanol 1.34
    morpholine-4-carbaldehyde 43.18
    sulfolane 122.8
    2,2,4-trimethylpentane 0.71
    2-methyltetrahydrofuran 17.66
    n-hexyl acetate 9.26
    isooctane 0.2
    2-(2-butoxyethoxy)ethanol 10.43
    sec-butyl acetate 6.51
    tert-butyl acetate 8.36
    decalin 1.61
    glycerin 2.65
    diglyme 32.67
    acrylic acid 9.48
    isopropyl myristate 3.37
    n-butyric acid 8.88
    acetyl acetate 12.16
    di(2-ethylhexyl) phthalate 4.25
    ethyl propionate 9.99
    nitromethane 28.66
    1,2-diethoxyethane 10.59
    benzonitrile 6.47
    trioctyl phosphate 2.96
    1-bromopropane 8.41
    gamma-valerolactone 53.97
    n-decanol 1.61
    triethyl phosphate 12.26
    4-methyl-2-pentanol 0.81
    propionitrile 2.95
    vinylene carbonate 24.46
    1,1,2-trichlorotrifluoroethane 51.81
    DMS 12.17
    cumene 2.46
    2-octanol 1.57
    2-hexanone 6.19
    octyl acetate 4.72
    limonene 5.53
    1,2-dimethoxyethane 13.62
    ethyl orthosilicate 10.76
    tributyl phosphate 4.42
    diacetone alcohol 7.99
    N,N-dimethylaniline 7.22
    acrylonitrile 4.89
    aniline 6.09
    1,3-propanediol 1.58
    bromobenzene 13.18
    dibromomethane 24.65
    1,1,2,2-tetrachloroethane 56.24
    2-methyl-cyclohexyl acetate 10.21
    tetrabutyl urea 7.67
    diisobutyl methanol 1.33
    2-phenylethanol 3.38
    styrene 3.9
    dioctyl adipate 8.43
    dimethyl sulfate 37.36
    ethyl butyrate 11.32
    methyl lactate 8.4
    butyl lactate 8.47
    diethyl carbonate 7.77
    propanediol butyl ether 5.06
    triethyl orthoformate 13.23
    p-tert-butyltoluene 2.91
    methyl 4-tert-butylbenzoate 15.82
    morpholine 15.14
    tert-butylamine 0.7
    n-dodecanol 1.13
    dimethoxymethane 10.16
    ethylene carbonate 18.41
    cyrene 22.75
    2-ethoxyethyl acetate 16.4
    2-ethylhexyl acetate 6.9
    1,2,4-trichlorobenzene 23.62
    4-methylpyridine 13.99
    dibutyl ether 4.9
    2,6-dimethyl-4-heptanol 1.33
    DEF 18.52
    dimethyl isosorbide 28.35
    tetrachloroethylene 33.54
    eugenol 11.1
    triacetin 23.45
    span 80 8.43
    1,4-butanediol 0.97
    1,1-dichloroethane 11.9
    2-methyl-1-pentanol 1.78
    methyl formate 9.13
    2-methyl-1-butanol 1.83
    n-decane 0.79
    butyronitrile 2.4
    3,7-dimethyl-1-octanol 2.09
    1-chlorooctane 3.42
    1-chlorotetradecane 1.13
    n-nonane 0.72
    undecane 0.49
    tert-butylcyclohexane 0.84
    cyclooctane 1.29
    cyclopentanol 5.41
    tetrahydropyran 11.69
    tert-amyl methyl ether 5.71
    2,5,8-trioxanonane 19.89
    1-hexene 1.39
    2-isopropoxyethanol 4.49
    2,2,2-trifluoroethanol 10.97
    methyl butyrate 12.63

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction