L-threonic acid magnesium salt

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  • Identifiers

    CAS number
    778571-57-6

    Molecular formula
    C8H14MgO10

    SMILES
    C([C@@H]([C@H](C(=O)[O-])O)O)O.C([C@@H]([C@H](C(=O)[O-])O)O)O.[Mg+2]

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 71.63%
    Sweet 41.81%
    Caramellic 32.23%
    Buttery 25.5%
    Milky 18.21%
    Clean 17.65%
    Sharp 17.19%
    Savory 15.63%
    Creamy 15.52%
    Sour 15.22%

     

    Flavor
    Odorless 73.19%
    Very mild 33.38%
    Sweet-like 28.31%
    Sweet 24.39%
    Bland 23.19%
    Mild 21.82%
    Caramellic 21.56%
    Sour 20.99%
    Yeast 20.33%
    Very slight 20.08%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    2.58 (strong acid)

    Molecular weight
    294.5 g/mol

    Flash point

    • 161.3 ˚C est.

  • Synonyms

    • L-Threonic acid magnesium salt
    • RefChem:155221
    • 778571-57-6
    • Magnesium L-Threonate
    • Magnesium (2R,3S)-2,3,4-trihydroxybutanoate
    • MFCD16621117
    • Magnesium L-threonate anhydrous
    • L-Threonic acid (magnesium)
    • C8H14MgO10
    • Magnesium bis[(2R,3S)-2,3,4-trihydroxybutanoate]
    • 1Y26ZZ0OTM
    • magnesium;(2R,3S)-2,3,4-trihydroxybutanoate
    • 2088918-94-7
    • UNII-1Y26ZZ0OTM
    • SCHEMBL29368984
    • DTXSID30670457
    • GLXC-15582
    • AKOS015896711
    • Magnesium, bis((2R,3S)-2,3,4-trihydroxybutanoato-kappaO,kappaO')-, (T-4)-
    • FB42384
    • MAGNESIUM L-THREONATE [WHO-DD]
    • PD199410
    • SY030313
    • DB-101157
    • HY-134240
    • CS-0140508
    • A839248
    • F079523
    • Q6731374
    • BIS[(2R,3S)-2,3,4-Trihydroxybutanoato-alphao,alphao']magnesium
    • Magnesium L-threonate;Magnesium (2R,3S)-2,3,4-trihydroxybutanoate
    • BIS[(2R,3S)-2,3,4-TRIHYDROXYBUTANOATO-ALPHAO,ALPHAO]MAGNESIUM
    • Magnesium (2R pound not3S)-2 pound not3 pound not4-trihydroxybutanoate
    • MAGNESIUM, BIS((2R,3S)-2,3,4-TRIHYDROXYBUTANOATO-.KAPPA.O,.KAPPA.O')-, (T-4)-
    • 778571-57-6

  • Applications

    Chemical name: L-threonic acid magnesium salt; CAS number: 778571-57-6. It is primarily used as a magnesium source in nutraceutical and pharmaceutical formulations, where it may serve as a dietary supplement ingredient with investigations into potential effects on cognitive function. In cosmetics and personal care, it can function as a magnesium-delivery salt in skin-care formulations. In chemical synthesis and industrial manufacturing, it may be considered an intermediate or a chelating-type salt for formulation work and metal-ion management. In research and development settings, it may be used as a magnesium source for analytical standards and formulation testing; it is also evaluated as a chelating agent to control trace metals in complex formulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 158.38
    methanol 611.39
    isopropanol 61.2
    water 3108.3
    ethyl acetate 8.08
    n-propanol 65.37
    acetone 45.2
    n-butanol 38.12
    acetonitrile 15.14
    DMF 1247.5
    toluene 1.43
    isobutanol 23.11
    1,4-dioxane 63.71
    methyl acetate 12.87
    THF 51.86
    2-butanone 16.52
    n-pentanol 12.62
    sec-butanol 33.67
    n-hexane 0.52
    ethylene glycol 1310.6
    NMP 491.21
    cyclohexane 3.14
    DMSO 2202.01
    n-butyl acetate 2.89
    n-octanol 5.6
    chloroform 1.48
    n-propyl acetate 3.57
    acetic acid 127.43
    dichloromethane 3.74
    cyclohexanone 21.41
    propylene glycol 385.18
    isopropyl acetate 4.67
    DMAc 446.31
    2-ethoxyethanol 164.28
    isopentanol 19.11
    n-heptane 2.11
    ethyl formate 19.56
    1,2-dichloroethane 6.87
    n-hexanol 11.62
    2-methoxyethanol 675.6
    isobutyl acetate 0.97
    tetrachloromethane 1.3
    n-pentyl acetate 2.29
    transcutol 92.44
    n-heptanol 7.54
    ethylbenzene 1.14
    MIBK 7.2
    2-propoxyethanol 65.38
    tert-butanol 58.74
    MTBE 8.27
    2-butoxyethanol 32.1
    propionic acid 53.9
    o-xylene 3.37
    formic acid 1500.68
    diethyl ether 10.22
    m-xylene 2.13
    p-xylene 1.11
    chlorobenzene 0.66
    dimethyl carbonate 23.93
    n-octane 0.74
    formamide 1496.53
    cyclopentanone 29.5
    2-pentanone 14.96
    anisole 4.72
    cyclopentyl methyl ether 15.37
    gamma-butyrolactone 47.13
    1-methoxy-2-propanol 241.5
    pyridine 10.58
    3-pentanone 10.1
    furfural 58.67
    n-dodecane 0.45
    diethylene glycol 240.32
    diisopropyl ether 2.53
    tert-amyl alcohol 36.15
    acetylacetone 23.21
    n-hexadecane 0.47
    acetophenone 6.82
    methyl propionate 19.71
    isopentyl acetate 1.98
    trichloroethylene 5.08
    n-nonanol 5.01
    cyclohexanol 28.14
    benzyl alcohol 12.22
    2-ethylhexanol 4.41
    isooctanol 4.68
    dipropyl ether 5.81
    1,2-dichlorobenzene 1.08
    ethyl lactate 16.59
    propylene carbonate 11.86
    n-methylformamide 540.66
    2-pentanol 18.09
    n-pentane 1.46
    1-propoxy-2-propanol 29.96
    1-methoxy-2-propyl acetate 10.17
    2-(2-methoxypropoxy) propanol 27.78
    mesitylene 2.26
    ε-caprolactone 19.79
    p-cymene 1.75
    epichlorohydrin 31.15
    1,1,1-trichloroethane 1.26
    2-aminoethanol 689.56
    morpholine-4-carbaldehyde 329.65
    sulfolane 197.69
    2,2,4-trimethylpentane 0.67
    2-methyltetrahydrofuran 19.53
    n-hexyl acetate 3.22
    isooctane 0.45
    2-(2-butoxyethoxy)ethanol 42.97
    sec-butyl acetate 1.9
    tert-butyl acetate 6.71
    decalin 0.67
    glycerin 938.82
    diglyme 81.9
    acrylic acid 87.64
    isopropyl myristate 1.65
    n-butyric acid 29.64
    acetyl acetate 4.83
    di(2-ethylhexyl) phthalate 2.85
    ethyl propionate 4.73
    nitromethane 173.67
    1,2-diethoxyethane 7.3
    benzonitrile 2.92
    trioctyl phosphate 3.12
    1-bromopropane 1.87
    gamma-valerolactone 99.85
    n-decanol 4.02
    triethyl phosphate 3.92
    4-methyl-2-pentanol 7.12
    propionitrile 7.73
    vinylene carbonate 11.79
    1,1,2-trichlorotrifluoroethane 103.35
    DMS 4.84
    cumene 1.08
    2-octanol 3.55
    2-hexanone 4.1
    octyl acetate 2.67
    limonene 3.05
    1,2-dimethoxyethane 96.42
    ethyl orthosilicate 3.53
    tributyl phosphate 2.43
    diacetone alcohol 44.76
    N,N-dimethylaniline 8.07
    acrylonitrile 16.23
    aniline 7.5
    1,3-propanediol 442.69
    bromobenzene 0.45
    dibromomethane 2.24
    1,1,2,2-tetrachloroethane 6.71
    2-methyl-cyclohexyl acetate 2.77
    tetrabutyl urea 6.71
    diisobutyl methanol 3.94
    2-phenylethanol 7.9
    styrene 1.07
    dioctyl adipate 3.47
    dimethyl sulfate 75.28
    ethyl butyrate 3.65
    methyl lactate 85.38
    butyl lactate 6.9
    diethyl carbonate 2.33
    propanediol butyl ether 36.42
    triethyl orthoformate 3.71
    p-tert-butyltoluene 1.97
    methyl 4-tert-butylbenzoate 10.78
    morpholine 109.89
    tert-butylamine 16.89
    n-dodecanol 3.32
    dimethoxymethane 154.91
    ethylene carbonate 9.48
    cyrene 55.99
    2-ethoxyethyl acetate 4.81
    2-ethylhexyl acetate 1.35
    1,2,4-trichlorobenzene 1.47
    4-methylpyridine 7.11
    dibutyl ether 2.42
    2,6-dimethyl-4-heptanol 3.94
    DEF 73.44
    dimethyl isosorbide 34.51
    tetrachloroethylene 7.73
    eugenol 15.28
    triacetin 6.43
    span 80 21.66
    1,4-butanediol 140.55
    1,1-dichloroethane 1.7
    2-methyl-1-pentanol 7.49
    methyl formate 216.1
    2-methyl-1-butanol 19.06
    n-decane 0.66
    butyronitrile 5.62
    3,7-dimethyl-1-octanol 3.52
    1-chlorooctane 1.32
    1-chlorotetradecane 0.69
    n-nonane 0.71
    undecane 0.53
    tert-butylcyclohexane 0.41
    cyclooctane 1.73
    cyclopentanol 37.83
    tetrahydropyran 16.62
    tert-amyl methyl ether 9.45
    2,5,8-trioxanonane 68.54
    1-hexene 0.88
    2-isopropoxyethanol 45.17
    2,2,2-trifluoroethanol 131.73
    methyl butyrate 7.31

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction