L-Cysteine hydrochloride monohydrate

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  • Identifiers

    CAS number
    7048-04-6

    Molecular formula
    C3H10ClNO3S

    SMILES
    C([C@@H](C(=O)O)N)S.O.Cl

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 59.32%
    Sulfurous 59.21%
    Meaty 48.38%
    Savory 40.61%
    Roasted 27.81%
    Cooked 27.08%
    Onion 23.08%
    Cheesy 22.32%
    Garlic 20.36%
    Alliaceous 19.99%

     

    Flavor
    Odorless 60.57%
    Sulfury 34.8%
    Mild 34.2%
    Sulfurous 26.42%
    Bland 25.4%
    Cooked 23.3%
    Yeast 22.79%
    Roasted 22.73%
    Faint 22.21%
    Sweet-like 21.89%

     

    Odor impact est.
    Medium

  • Properties

    pKa est.
    6.75 (neutral)

    Molecular weight
    175.64 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    277°C

    Flash point

    • 134.28 ˚C est.

  • Synonyms

    • L-Cysteine hydrochloride monohydrate
    • 7048-04-6
    • H-Cys-OH.HCl.H2O
    • L-Cysteine hydrochloride hydrate
    • (R)-2-Amino-3-mercaptopropanoic acid hydrochloride hydrate
    • cysteine hydrochloride monohydrate
    • Cysteine HCl
    • MFCD00065606
    • 345909-32-2
    • L-CYSTEINE HCl MONOHYDRATE
    • L-Cysteine monohydrate monochloride
    • DL-Cysteine HCl Monohydrate
    • Cysteine, hydrochloride, hydrate (1:1:1)
    • ZT934N0X4W
    • (2R)-2-amino-3-sulfanylpropanoic acid;hydrate;hydrochloride
    • L-cysteine hydrate hydrochloride
    • L-Cysteine (hydrochloride hydrate)
    • L-cysteine monohydrochloride monohydrate
    • (R)-2-Amino-3-mercaptopropanoic acid hydrochloride xhydrate
    • ELCYS
    • NOURESS
    • H-Cys-OH.HCl
    • Cysteine hydrochloride (USP)
    • Cysteine hydrochloride [USP]
    • (2R)-2-Amino-3-sulfanyl-propanoic acid hydrochloride monohydrate
    • CYSTEINE HYDROCHLORIDE [II]
    • NSC-755898
    • L-CysteineHclMonohydrate
    • CYSTEINE HYDROCHLORIDE [USP MONOGRAPH]
    • 345909-32-2 (.xH2O)
    • Cysteine hydrochloride monohydrate; (2R)-2-amino-3-sulfanylpropanoic acid hydrochloride
    • CYSTEINE HYDROCHLORIDE MONOHYDRATE [EP IMPURITY]
    • CYSTEINE HYDROCHLORIDE MONOHYDRATE [EP MONOGRAPH]
    • Elcys (TN)
    • Cysteine hydrochloride monohydrate, L-
    • UNII-ZT934N0X4W
    • SCHEMBL43390
    • cysteine hydrochloride hydrate
    • CHEBI:91248
    • DTXSID90990688
    • Cysteini hydrochloridum monohydricum
    • HY-W016715R
    • AC8040
    • CYSTEINE HYDROCHLORIDE [VANDF]
    • AKOS015855408
    • AKOS015907763
    • CS-W017431
    • FC16021
    • HY-W016715
    • L-Cysteine hydrochloride hydrate, 99%
    • L-cysteine monohydrochloride-monohydrate
    • NSC 755898
    • L-cysteine hydrochloride--water (1/1)
    • FL168430
    • L-Cysteine hydrochloride hydrate (JP17)
    • L-CYSTEINE MONOHYDROCHLORIDE [FCC]
    • TS-03861
    • CYSTEINE HYDROCHLORIDE [ORANGE BOOK]
    • NS00078059
    • L-Cysteine (hydrochloride hydrate) (Standard)
    • L-CYSTEINE HYDROCHLORIDE HYDRATE [JAN]
    • L-CYSTEINE, HYDROCHLORIDE, MONOHYDRATE
    • CYSTEINE, L-, HYDROCHLORIDE MONOHYDRATE
    • D02326
    • EC 615-117-8
    • L-Cysteine hydrochloride monohydrate, USP grade
    • SBI-0633588.0002
    • L-Cysteine hydrochloride hydrate,98.5-101.5%
    • CYSTEINE HYDROCHLORIDE MONOHYDRATE [WHO-DD]
    • L-Cysteine hydrochloride monohydrate, p.a., 98.5%
    • L-Cysteine hydrochloride monohydrate, >=99.0% (RT)
    • L-CYSTEINE, HYDROCHLORIDE, HYDRATE (1:1:1)
    • Q27163159
    • (R)-2-Amino-3-mercaptopropanoicacidhydrochloridexhydrate
    • L-Cysteine hydrochloride monohydrate, BioUltra, >=99.0% (RT)
    • (1R)-1-carboxy-2-sulfanylethan-1-aminium chloride--water (1/1)
    • L-Cysteine hydrochloride monohydrate, JIS special grade, >=99.0%
    • L-Cysteine hydrochloride monohydrate, reagent grade, >=98% (TLC)
    • L-Cysteine hydrochloride monohydrate, tested according to Ph.Eur.
    • (R)-2-Amino-3-mercaptopropionic acid hydrochloride monohydrate;L-Cys-OH.HCl.H2O
    • Cysteine hydrochloride monohydrate, European Pharmacopoeia (EP) Reference Standard
    • L-Cysteine hydrochloride, United States Pharmacopeia (USP) Reference Standard
    • L-Cysteine hydrochloride monohydrate, 99%, FG, produced by Wacker Chemie AG, Burghausen, Germany
    • L-Cysteine hydrochloride monohydrate, FG, produced by Wacker Chemie AG, Burghausen, Germany, Food, 20 mesh
    • L-Cysteine hydrochloride monohydrate, from non-animal source, cell culture tested, meets EP, USP testing specifications
    • L-Cysteine hydrochloride monohydrate, Pharmaceutical Secondary Standard; Certified Reference Material
    • L-Cysteine hydrochloride monohydrate, Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, 98.5-101.0% (Ph.Eur (2.2.20))

  • Applications

    L-Cysteine hydrochloride monohydrate (CAS 7048-04-6) is used across several industries as a functional ingredient and chemical intermediate; in food processing it serves as a dough conditioner to improve dough extensibility and reduce mixing time; in cosmetics and personal care it acts as a reducing agent in some hair care formulations and can serve as a conditioning-related component; in pharmaceuticals and biotech it is employed as a synthetic intermediate for peptides and other drug substances; in laboratory and analytical chemistry it is used as a reducing agent and a thiol-based reagent for sample preparation and analysis; in polymer and materials chemistry it can serve as a building block for cysteine-containing polymers and functional materials; it may also be used as a cysteine source in formulated nutraceuticals or culture media, depending on local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.75
    methanol 5.92
    isopropanol 0.24
    water 172.13
    ethyl acetate 0.06
    n-propanol 0.21
    acetone 12.09
    n-butanol 0.1
    acetonitrile 0.06
    DMF 8.22
    toluene 0.03
    isobutanol 0.06
    1,4-dioxane 0.21
    methyl acetate 0.08
    THF 0.85
    2-butanone 0.27
    n-pentanol 0.13
    sec-butanol 0.06
    n-hexane 0.04
    ethylene glycol 11.84
    NMP 14.48
    cyclohexane 0.05
    DMSO 44.98
    n-butyl acetate 0.18
    n-octanol 0.22
    chloroform 0.02
    n-propyl acetate 0.1
    acetic acid 13.26
    dichloromethane 0.03
    cyclohexanone 0.75
    propylene glycol 2.4
    isopropyl acetate 0.12
    DMAc 4.65
    2-ethoxyethanol 1.8
    isopentanol 0.12
    n-heptane 0.09
    ethyl formate 0.26
    1,2-dichloroethane 0.05
    n-hexanol 0.24
    2-methoxyethanol 3.77
    isobutyl acetate 0.08
    tetrachloromethane 0.04
    n-pentyl acetate 0.28
    transcutol 6.92
    n-heptanol 0.4
    ethylbenzene 0.03
    MIBK 0.38
    2-propoxyethanol 1.61
    tert-butanol 0.55
    MTBE 0.09
    2-butoxyethanol 1.84
    propionic acid 0.63
    o-xylene 0.08
    formic acid 70.31
    diethyl ether 0.06
    m-xylene 0.08
    p-xylene 0.07
    chlorobenzene 0.03
    dimethyl carbonate 0.22
    n-octane 0.05
    formamide 32.89
    cyclopentanone 1.57
    2-pentanone 0.36
    anisole 0.09
    cyclopentyl methyl ether 0.21
    gamma-butyrolactone 1.36
    1-methoxy-2-propanol 1.56
    pyridine 0.15
    3-pentanone 0.17
    furfural 2.9
    n-dodecane 0.03
    diethylene glycol 6.95
    diisopropyl ether 0.07
    tert-amyl alcohol 0.22
    acetylacetone 1.95
    n-hexadecane 0.03
    acetophenone 0.31
    methyl propionate 0.09
    isopentyl acetate 0.22
    trichloroethylene 0.08
    n-nonanol 0.25
    cyclohexanol 0.15
    benzyl alcohol 0.24
    2-ethylhexanol 0.2
    isooctanol 0.37
    dipropyl ether 0.19
    1,2-dichlorobenzene 0.04
    ethyl lactate 0.45
    propylene carbonate 0.57
    n-methylformamide 2.79
    2-pentanol 0.07
    n-pentane 0.03
    1-propoxy-2-propanol 1.07
    1-methoxy-2-propyl acetate 0.56
    2-(2-methoxypropoxy) propanol 3.06
    mesitylene 0.14
    ε-caprolactone 0.46
    p-cymene 0.15
    epichlorohydrin 0.26
    1,1,1-trichloroethane 0.03
    2-aminoethanol 4.51
    morpholine-4-carbaldehyde 5.21
    sulfolane 10.43
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 0.19
    n-hexyl acetate 0.3
    isooctane 0.03
    2-(2-butoxyethoxy)ethanol 3.95
    sec-butyl acetate 0.07
    tert-butyl acetate 0.38
    decalin 0.03
    glycerin 13.26
    diglyme 5.36
    acrylic acid 1.9
    isopropyl myristate 0.2
    n-butyric acid 0.47
    acetyl acetate 0.24
    di(2-ethylhexyl) phthalate 0.7
    ethyl propionate 0.07
    nitromethane 6.15
    1,2-diethoxyethane 0.35
    benzonitrile 0.08
    trioctyl phosphate 0.52
    1-bromopropane 0.02
    gamma-valerolactone 3.09
    n-decanol 0.22
    triethyl phosphate 0.28
    4-methyl-2-pentanol 0.13
    propionitrile 0.03
    vinylene carbonate 0.45
    1,1,2-trichlorotrifluoroethane 2.45
    DMS 0.32
    cumene 0.07
    2-octanol 0.21
    2-hexanone 0.23
    octyl acetate 0.28
    limonene 0.19
    1,2-dimethoxyethane 1.29
    ethyl orthosilicate 0.26
    tributyl phosphate 0.46
    diacetone alcohol 1.83
    N,N-dimethylaniline 0.26
    acrylonitrile 0.08
    aniline 0.1
    1,3-propanediol 2.18
    bromobenzene 0.02
    dibromomethane 0.03
    1,1,2,2-tetrachloroethane 0.08
    2-methyl-cyclohexyl acetate 0.39
    tetrabutyl urea 1.08
    diisobutyl methanol 0.3
    2-phenylethanol 0.38
    styrene 0.03
    dioctyl adipate 0.48
    dimethyl sulfate 1.3
    ethyl butyrate 0.18
    methyl lactate 0.88
    butyl lactate 0.9
    diethyl carbonate 0.12
    propanediol butyl ether 3.03
    triethyl orthoformate 0.26
    p-tert-butyltoluene 0.17
    methyl 4-tert-butylbenzoate 1.74
    morpholine 0.26
    tert-butylamine 0.19
    n-dodecanol 0.19
    dimethoxymethane 1.45
    ethylene carbonate 0.25
    cyrene 5.02
    2-ethoxyethyl acetate 0.56
    2-ethylhexyl acetate 0.16
    1,2,4-trichlorobenzene 0.07
    4-methylpyridine 0.11
    dibutyl ether 0.12
    2,6-dimethyl-4-heptanol 0.3
    DEF 0.47
    dimethyl isosorbide 4.57
    tetrachloroethylene 0.16
    eugenol 2.24
    triacetin 1.11
    span 80 3.08
    1,4-butanediol 1.2
    1,1-dichloroethane 0.02
    2-methyl-1-pentanol 0.13
    methyl formate 2.46
    2-methyl-1-butanol 0.07
    n-decane 0.04
    butyronitrile 0.04
    3,7-dimethyl-1-octanol 0.24
    1-chlorooctane 0.05
    1-chlorotetradecane 0.04
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.03
    cyclooctane 0.04
    cyclopentanol 0.3
    tetrahydropyran 0.08
    tert-amyl methyl ether 0.09
    2,5,8-trioxanonane 6.23
    1-hexene 0.04
    2-isopropoxyethanol 0.83
    2,2,2-trifluoroethanol 5.9
    methyl butyrate 0.14

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction