Kaurane-16,18-diol, 18-acetate, (4alpha)-

Overview IFRA Request a quote

  • Identifiers

    CAS number
    30320-70-8

    Molecular formula
    C22H36O3

    SMILES
    CC(=O)OC[C@@]1(CCC[C@@]2([C@@H]1CC[C@]34[C@H]2CC[C@@H](C3)[C@](C4)(C)O)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 81.19%
    Amber 54.54%
    Cedar 45.88%
    Dry 45.49%
    Balsamic 44.23%
    Sweet 40.52%
    Musk 39.69%
    Sandalwood 37.57%
    Earthy 36.85%
    Fruity 35.13%

     

    Flavor
    Sweet 56.01%
    Woody 42.18%
    Herbal 41.87%
    Pine 40.95%
    Earthy 38.83%
    Camphor 36.6%
    Balsam 34.41%
    Dry 33.19%
    Fruit 32.3%
    Fresh 32.29%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.1

    pKa est.
    7.28 (neutral)

    Molecular weight
    348.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    433°C

    Flash point

    • 206.75 ˚C est.

  • Synonyms

    • 30320-70-8
    • Kaurane-16,18-diol, 18-acetate, (4.alpha.)-
    • RefChem:350356
    • Kaurane-16,18-diol, 18-acetate, (4alpha)-
    • DTXSID201286471
    • Kaurane-16,18-diol, 18-acetate, (4I+/-)-
    • 16-Hydroxy-5beta,8alpha,9beta,10alpha,16beta-kauran-18-yl acetate
    • 30320-70-8

  • Applications

    Kaurane-16,18-diol, 18-acetate, (4alpha)- (CAS number: 30320-70-8) is primarily used as an intermediate in the synthesis of kaurane-type diterpenoids and their natural-product analogs, serving as a key chiral scaffold for asymmetric synthesis and for developing complex derivatives in pharmaceutical and agrochemical research. It can also be employed as a reference standard for analytical characterization of kaurane-type compounds. In industrial R&D, it may be utilized as a building block for library generation of diterpenoid-like molecules and for advancing discovery in pharmaceutical and agrochemical areas. Its specific applications depend on local regulations and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 65.05
    methanol 49.27
    isopropanol 70.75
    water 0.57
    ethyl acetate 121.16
    n-propanol 84.01
    acetone 144.11
    n-butanol 81.91
    acetonitrile 96.04
    DMF 256.79
    toluene 200.17
    isobutanol 61.28
    1,4-dioxane 204.5
    methyl acetate 83.99
    THF 595.38
    2-butanone 107.75
    n-pentanol 36.37
    sec-butanol 32.48
    n-hexane 1.82
    ethylene glycol 10.85
    NMP 162.89
    cyclohexane 7.75
    DMSO 101.67
    n-butyl acetate 74.33
    n-octanol 21.33
    chloroform 373.03
    n-propyl acetate 60.56
    acetic acid 84.79
    dichloromethane 219.11
    cyclohexanone 182.37
    propylene glycol 19.48
    isopropyl acetate 115.23
    DMAc 169.59
    2-ethoxyethanol 67.97
    isopentanol 65.78
    n-heptane 1.76
    ethyl formate 52.49
    1,2-dichloroethane 119.98
    n-hexanol 53.37
    2-methoxyethanol 147.28
    isobutyl acetate 58.41
    tetrachloromethane 38.66
    n-pentyl acetate 58.8
    transcutol 243.03
    n-heptanol 32.52
    ethylbenzene 43.68
    MIBK 94.44
    2-propoxyethanol 171.2
    tert-butanol 55.83
    MTBE 50.38
    2-butoxyethanol 87.19
    propionic acid 57.02
    o-xylene 65.71
    formic acid 32.58
    diethyl ether 81.75
    m-xylene 109.72
    p-xylene 51.03
    chlorobenzene 148.03
    dimethyl carbonate 82.62
    n-octane 0.73
    formamide 54.72
    cyclopentanone 255.93
    2-pentanone 120.74
    anisole 99.66
    cyclopentyl methyl ether 167.28
    gamma-butyrolactone 268.12
    1-methoxy-2-propanol 174.47
    pyridine 246.72
    3-pentanone 86.16
    furfural 220.81
    n-dodecane 0.64
    diethylene glycol 104.91
    diisopropyl ether 25.58
    tert-amyl alcohol 27.73
    acetylacetone 178.98
    n-hexadecane 0.81
    acetophenone 92.31
    methyl propionate 110.85
    isopentyl acetate 80.87
    trichloroethylene 284.57
    n-nonanol 23.74
    cyclohexanol 64.22
    benzyl alcohol 79.44
    2-ethylhexanol 28.34
    isooctanol 27.9
    dipropyl ether 35.94
    1,2-dichlorobenzene 113.95
    ethyl lactate 44.31
    propylene carbonate 132.65
    n-methylformamide 99.07
    2-pentanol 41.5
    n-pentane 3.22
    1-propoxy-2-propanol 114.98
    1-methoxy-2-propyl acetate 151.44
    2-(2-methoxypropoxy) propanol 75.16
    mesitylene 46.89
    ε-caprolactone 161.45
    p-cymene 23.88
    epichlorohydrin 291.69
    1,1,1-trichloroethane 124.44
    2-aminoethanol 37.33
    morpholine-4-carbaldehyde 210.82
    sulfolane 195.65
    2,2,4-trimethylpentane 1.86
    2-methyltetrahydrofuran 171.22
    n-hexyl acetate 66.76
    isooctane 2.21
    2-(2-butoxyethoxy)ethanol 100.4
    sec-butyl acetate 54.28
    tert-butyl acetate 108.5
    decalin 3.81
    glycerin 42.61
    diglyme 177.79
    acrylic acid 56.68
    isopropyl myristate 25.42
    n-butyric acid 108.01
    acetyl acetate 116.09
    di(2-ethylhexyl) phthalate 35.46
    ethyl propionate 65.17
    nitromethane 159.32
    1,2-diethoxyethane 70.61
    benzonitrile 107.05
    trioctyl phosphate 24.39
    1-bromopropane 61.87
    gamma-valerolactone 344.01
    n-decanol 15.28
    triethyl phosphate 34.14
    4-methyl-2-pentanol 32.8
    propionitrile 91.65
    vinylene carbonate 138.74
    1,1,2-trichlorotrifluoroethane 155.25
    DMS 78.38
    cumene 25.03
    2-octanol 16.59
    2-hexanone 53.17
    octyl acetate 32.06
    limonene 24.75
    1,2-dimethoxyethane 122.87
    ethyl orthosilicate 33.07
    tributyl phosphate 25.85
    diacetone alcohol 102.12
    N,N-dimethylaniline 58.32
    acrylonitrile 114.08
    aniline 155.91
    1,3-propanediol 74.46
    bromobenzene 161.24
    dibromomethane 133.19
    1,1,2,2-tetrachloroethane 215.37
    2-methyl-cyclohexyl acetate 58.27
    tetrabutyl urea 33.92
    diisobutyl methanol 19.17
    2-phenylethanol 90.19
    styrene 55.38
    dioctyl adipate 40.68
    dimethyl sulfate 102.77
    ethyl butyrate 59.73
    methyl lactate 74.02
    butyl lactate 58.45
    diethyl carbonate 43.61
    propanediol butyl ether 65.64
    triethyl orthoformate 50.4
    p-tert-butyltoluene 23.11
    methyl 4-tert-butylbenzoate 83.81
    morpholine 228.54
    tert-butylamine 29.32
    n-dodecanol 9.76
    dimethoxymethane 252.86
    ethylene carbonate 120.49
    cyrene 85.86
    2-ethoxyethyl acetate 102.99
    2-ethylhexyl acetate 60.8
    1,2,4-trichlorobenzene 139.96
    4-methylpyridine 238.76
    dibutyl ether 18.62
    2,6-dimethyl-4-heptanol 19.17
    DEF 98.52
    dimethyl isosorbide 144.62
    tetrachloroethylene 129.22
    eugenol 84.4
    triacetin 85.17
    span 80 61.06
    1,4-butanediol 21.56
    1,1-dichloroethane 128.75
    2-methyl-1-pentanol 31.11
    methyl formate 67.04
    2-methyl-1-butanol 48.61
    n-decane 1.42
    butyronitrile 86.44
    3,7-dimethyl-1-octanol 24.69
    1-chlorooctane 10.79
    1-chlorotetradecane 3.23
    n-nonane 1.11
    undecane 0.91
    tert-butylcyclohexane 3.08
    cyclooctane 2.66
    cyclopentanol 71.42
    tetrahydropyran 197.19
    tert-amyl methyl ether 33.86
    2,5,8-trioxanonane 109.2
    1-hexene 9.93
    2-isopropoxyethanol 56.17
    2,2,2-trifluoroethanol 47.5
    methyl butyrate 70.11

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction