Jwh-200

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  • Identifiers

    CAS number
    103610-04-4

    Molecular formula
    C25H24N2O2

    SMILES
    C1COCCN1CCN2C=C(C3=CC=CC=C32)C(=O)C4=CC=CC5=CC=CC=C54

  • Odor profile

    Fragrance
    Odorless 36.55%
    Floral 29.81%
    Animal 29.6%
    Grape 27.63%
    Neroli 24.64%
    Fruity 23.63%
    Sweet 22.44%
    Honey 21.32%
    Cooked 20.97%
    Bitter 20.85%

     

    Flavor
    Bitter 89.88%
    Odorless 21.83%
    Very strong 20.06%
    Nitrile 19.65%
    Indole 19.6%
    Cedarleaf 19.27%
    Animal 18.93%
    Moth ball 18.72%
    Cereal 18.63%
    Sweet-like 18.56%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.2

    pKa est.
    6.37 (neutral)

    Molecular weight
    384.5 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    889°C

    Flash point

    • 276.7 ˚C est.

  • Synonyms

    • 103610-04-4
    • JWH-200
    • 1-(2-(4-Morpholinyl)ethyl)-3-(1-naphthoyl) indole
    • JWH 200
    • UNII-9HN5J913P3
    • DEA No. 7200
    • HSDB 8000
    • [1-[2-(4-Morpholinyl)ethyl]-1H-indol-3-yl]-1-naphthalenylmethanone
    • 9HN5J913P3
    • 1-(2-(4-Morpholinyl)ethyl)-3-(1-naphthoyl)indole
    • CHEMBL13078
    • (1-(2-morpholinoethyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone
    • DTXSID60145946
    • WIN-55255
    • J378.966G
    • [1-(2-morpholin-4-ylethyl)indol-3-yl]-naphthalen-1-ylmethanone
    • JWH 200-d5
    • [1-{2-(4-Morpholinyl)ethyl}-1H-indol-3-yl]-1-naphthalenylmethanone
    • 1-(2-(4-MORPHOLINYL)ETHYL)-3-(1-NAPHTHOYL)INDOLE [HSDB]
    • METHANONE, (1-(2-(4-MORPHOLINYL)ETHYL)-1H-INDOL-3-YL)-1-NAPHTHALENYL-
    • 1-[2-(4-Morpholinyl)ethyl]-3-(1-naphthoyl) indole
    • 1-[2-(4-Morpholinyl)ethyl]-3-(1-naphthoyl)indole JWH 200
    • (1-(2-morpholin-4-ylethyl)indol-3-yl)-naphthalen-1-ylmethanone
    • [1-(2-(4-Morpholinyl)ethyl)-1H-indol-3-yl]-1-naphthalenylmethanone
    • 1-[2-(4-Morpholinyl)ethyl]-3-(1-naphthoyl)indole JWH 200 (1.0mg/ml in Acetonitrile)
    • Methanone, [1-[2-(4-morpholinyl)ethyl]-1H-indol-3-yl]-1-naphthalenyl-; JWH 200; WIN 55255; [1-[2-(4-Morpholinyl)ethyl]-1H-indol-3-yl]-1-naphthalenylmethanone; JWH-200; [1-(2-Morpholinoethyl)-1H-indol-3-yl](naphthalen-1-yl)methanone
    • DTXCID1068437
    • SCHEMBL10093017
    • JWH-200, 1mg/ml in Methanol
    • SZWYXJHTNGJPKU-UHFFFAOYSA-N
    • 1-[2-(4-Morpholinyl)ethyl]-3-(1-naphthoyl)indoleJWH 200
    • BRC83351
    • JWH-200, 0.1mg/ml in Methanol
    • BDBM50009854
    • AKOS015909676
    • CCG-208717
    • FM26088
    • JWH-200 (WIN 55,225)
    • NS00001109
    • Q4041745
    • (1-(2-Morpholin-4-ylethyl)indol-3-yl)-naphthalen-1-yl)methanone
    • 1-naphthalenyl(1-(2-(4-morpholinyl)ethyl)-1h-indol-3-yl)methanone
    • [1-(2-Morpholin-4-yl-ethyl)-1H-indol-3-yl]-naphthalen-1-yl-methanone
    • [1-[2-(4-Morpholinyl)ethyl]-1H-indol-3-yl]-1-naphthalenyl-methanone;1-[2-(4-Morpholinyl)ethyl]-3-(1-naphthoyl)indole

  • Applications

    Jwh-200 (CAS 103610-04-4) is a synthetic cannabinoid primarily used in research settings as a ligand for cannabinoid receptors CB1/CB2 to study pharmacology and receptor interactions. In practice it is commonly used as an analytical reference standard in chromatographic methods such as LC-MS or GC-MS to identify and quantify related cannabinoids in forensic and toxicology work. It can also serve as a scaffold in medicinal chemistry research to explore structure-activity relationships and support the development of related synthetic cannabinoid compounds. Additionally, it may be used as a synthetic intermediate for preparing related cannabinoids or analytical materials, depending on laboratory synthesis capabilities. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 8.05
    methanol 9.17
    isopropanol 4.35
    water 0.05
    ethyl acetate 9.37
    n-propanol 8.74
    acetone 14.96
    n-butanol 7.24
    acetonitrile 4.65
    DMF 29.99
    toluene 7.27
    isobutanol 6.34
    1,4-dioxane 23.71
    methyl acetate 13.96
    THF 41.01
    2-butanone 22.45
    n-pentanol 6.74
    sec-butanol 5.66
    n-hexane 0.27
    ethylene glycol 3.66
    NMP 18.73
    cyclohexane 0.5
    DMSO 35.25
    n-butyl acetate 6.6
    n-octanol 1.75
    chloroform 119.09
    n-propyl acetate 8.27
    acetic acid 23.49
    dichloromethane 126.59
    cyclohexanone 26.2
    propylene glycol 3.17
    isopropyl acetate 5.98
    DMAc 55.98
    2-ethoxyethanol 19.77
    isopentanol 6.67
    n-heptane 0.29
    ethyl formate 10.55
    1,2-dichloroethane 55.1
    n-hexanol 4.26
    2-methoxyethanol 24.39
    isobutyl acetate 6.3
    tetrachloromethane 5.12
    n-pentyl acetate 6.11
    transcutol 49.76
    n-heptanol 2.86
    ethylbenzene 3.22
    MIBK 7.24
    2-propoxyethanol 18.39
    tert-butanol 3.14
    MTBE 2.96
    2-butoxyethanol 12.26
    propionic acid 11.49
    o-xylene 3.17
    formic acid 15.54
    diethyl ether 6.97
    m-xylene 2.97
    p-xylene 4.57
    chlorobenzene 14.05
    dimethyl carbonate 8.65
    n-octane 0.19
    formamide 21.94
    cyclopentanone 30.78
    2-pentanone 11.84
    anisole 6.77
    cyclopentyl methyl ether 9.62
    gamma-butyrolactone 32.56
    1-methoxy-2-propanol 13.32
    pyridine 35.73
    3-pentanone 12.86
    furfural 37.47
    n-dodecane 0.17
    diethylene glycol 16.94
    diisopropyl ether 1.35
    tert-amyl alcohol 3.92
    acetylacetone 13.99
    n-hexadecane 0.19
    acetophenone 10.34
    methyl propionate 11.49
    isopentyl acetate 7.24
    trichloroethylene 117.1
    n-nonanol 2.27
    cyclohexanol 6.66
    benzyl alcohol 11.34
    2-ethylhexanol 3.23
    isooctanol 2.84
    dipropyl ether 4.5
    1,2-dichlorobenzene 12.6
    ethyl lactate 6.53
    propylene carbonate 13.97
    n-methylformamide 16.07
    2-pentanol 3.89
    n-pentane 0.28
    1-propoxy-2-propanol 9.89
    1-methoxy-2-propyl acetate 10.29
    2-(2-methoxypropoxy) propanol 13.2
    mesitylene 1.31
    ε-caprolactone 20.32
    p-cymene 2.17
    epichlorohydrin 75.07
    1,1,1-trichloroethane 20.05
    2-aminoethanol 6.95
    morpholine-4-carbaldehyde 29.17
    sulfolane 31.4
    2,2,4-trimethylpentane 0.23
    2-methyltetrahydrofuran 15.91
    n-hexyl acetate 5.02
    isooctane 0.12
    2-(2-butoxyethoxy)ethanol 17.11
    sec-butyl acetate 5.82
    tert-butyl acetate 4.63
    decalin 0.37
    glycerin 8.45
    diglyme 35.59
    acrylic acid 14.5
    isopropyl myristate 2.8
    n-butyric acid 13.27
    acetyl acetate 6.82
    di(2-ethylhexyl) phthalate 4.78
    ethyl propionate 7.29
    nitromethane 36.58
    1,2-diethoxyethane 12.97
    benzonitrile 10.14
    trioctyl phosphate 2.64
    1-bromopropane 17.7
    gamma-valerolactone 46.72
    n-decanol 1.78
    triethyl phosphate 5.41
    4-methyl-2-pentanol 2.64
    propionitrile 7.57
    vinylene carbonate 18.37
    1,1,2-trichlorotrifluoroethane 48.2
    DMS 8.37
    cumene 2.3
    2-octanol 1.64
    2-hexanone 10.42
    octyl acetate 3.51
    limonene 2.37
    1,2-dimethoxyethane 27.89
    ethyl orthosilicate 5.34
    tributyl phosphate 3.66
    diacetone alcohol 8.36
    N,N-dimethylaniline 5.13
    acrylonitrile 11.96
    aniline 11.24
    1,3-propanediol 10.53
    bromobenzene 13.19
    dibromomethane 58.47
    1,1,2,2-tetrachloroethane 75.63
    2-methyl-cyclohexyl acetate 7.25
    tetrabutyl urea 5.41
    diisobutyl methanol 1.86
    2-phenylethanol 9.18
    styrene 4.13
    dioctyl adipate 6.05
    dimethyl sulfate 14.06
    ethyl butyrate 6.58
    methyl lactate 8.37
    butyl lactate 6.85
    diethyl carbonate 5.89
    propanediol butyl ether 6.43
    triethyl orthoformate 6.39
    p-tert-butyltoluene 1.64
    methyl 4-tert-butylbenzoate 8.96
    morpholine 28.26
    tert-butylamine 1.62
    n-dodecanol 1.42
    dimethoxymethane 20.31
    ethylene carbonate 13.91
    cyrene 14.06
    2-ethoxyethyl acetate 13.32
    2-ethylhexyl acetate 5.92
    1,2,4-trichlorobenzene 17.19
    4-methylpyridine 19.67
    dibutyl ether 3.44
    2,6-dimethyl-4-heptanol 1.86
    DEF 14.4
    dimethyl isosorbide 20.42
    tetrachloroethylene 45.65
    eugenol 11.86
    triacetin 9.5
    span 80 8.52
    1,4-butanediol 5.22
    1,1-dichloroethane 29.9
    2-methyl-1-pentanol 6.92
    methyl formate 14.7
    2-methyl-1-butanol 6.98
    n-decane 0.28
    butyronitrile 6.62
    3,7-dimethyl-1-octanol 2.37
    1-chlorooctane 1.48
    1-chlorotetradecane 0.71
    n-nonane 0.22
    undecane 0.21
    tert-butylcyclohexane 0.29
    cyclooctane 0.15
    cyclopentanol 7.51
    tetrahydropyran 17.31
    tert-amyl methyl ether 3.43
    2,5,8-trioxanonane 25.09
    1-hexene 1.92
    2-isopropoxyethanol 12.97
    2,2,2-trifluoroethanol 13.0
    methyl butyrate 9.41

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction