Ipconazole

Overview IFRA Request a quote

  • Identifiers

    CAS number
    125225-28-7

    Molecular formula
    C18H24ClN3O

    SMILES
    CC(C)C1CCC(C1(CN2C=NC=N2)O)CC3=CC=C(C=C3)Cl

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Animal 30.71%
    Floral 28.54%
    Odorless 28.28%
    Fruity 27.32%
    Fresh 27.23%
    Mint 26.38%
    Cooling 26.3%
    Woody 24.73%
    Grapefruit 24.07%
    Sweet 23.45%

     

    Flavor
    Bitter 52.63%
    Fruity 28.0%
    Mild 24.42%
    Herbal 23.99%
    Green 23.15%
    Odorless 22.26%
    Cedarleaf 21.51%
    Earthy 20.82%
    Green pepper 20.09%
    Syrup 19.93%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.1

    pKa est.
    6.33 (neutral)

    Molecular weight
    333.9 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point est.
    420°C

    Flash point

    • 191.12 ˚C est.

  • Synonyms

    • Ipconazole
    • 125225-28-7
    • DTXSID7034674
    • DTXCID5014674
    • CHEBI:81770
    • FC61260G4Q
    • 2-((4-chlorophenyl)methyl)-5-(1-methylethyl)-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol
    • 2-[(4-chlorophenyl)methyl]-5-(1-methylethyl)-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol
    • Cyclopentanol, 2-((4-chlorophenyl)methyl)-5-(1-methylethyl)-1-(1H-1,2,4-triazol-1-ylmethyl)-
    • RefChem:1087420
    • 603-038-1
    • ipconazole (ISO); (1RS,2SR,5RS;1RS,2SR,5SR)-2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol
    • 2-[(4-chlorophenyl)methyl]-5-propan-2-yl-1-(1,2,4-triazol-1-ylmethyl)cyclopentan-1-ol
    • Ipconazole [ISO]
    • Rancona
    • UNII-FC61260G4Q
    • SCHEMBL21696
    • orb1738353
    • CHEMBL3185422
    • MSK21316
    • Tox21_302497
    • HY-W331786
    • NCGC00256739-01
    • 2-[(4-chlorophenyl)methyl]-5-(propan-2-yl)-1-[(1H-1,2,4-triazol-1-yl)methyl]cyclopentan-1-ol
    • FI176352
    • CAS-125225-28-7
    • CS-0443246
    • NS00002872
    • C18471
    • Q17153868
    • 1-((1H-1,2,4-triazol-1-yl)methyl)-2-(4-chlorobenzyl)-5-isopropylcyclopentan-1-ol
    • 2-(4-chlorobenzyl)-5-isopropyl-1-(1H-1,2,4-triazol-1-ylmethyl)cyclopentanol
    • 2-[(4-chlorophenyl)methyl]-5-isopropyl-1-(1,2,4-triazol-1-ylmethyl)cyclopentanol
    • 125225-28-7

  • Applications

    Ipconazole (CAS 125225-28-7) is a systemic triazole fungicide used in agriculture to control fungal pathogens by inhibiting ergosterol biosynthesis. Typical applications include seed treatment to protect cereals, fruits, and vegetables from seed-borne diseases; foliar and soil treatments to provide systemic protection for crops such as cereals, fruits, and vegetables; use in nursery stock and greenhouse crops (ornamentals) to manage common fungal diseases; and formulations for seed coatings or controlled-release delivery to extend protection.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 166.36
    methanol 183.01
    isopropanol 114.4
    water 0.3
    ethyl acetate 180.84
    n-propanol 134.8
    acetone 249.08
    n-butanol 147.64
    acetonitrile 50.67
    DMF 181.04
    toluene 203.31
    isobutanol 99.33
    1,4-dioxane 289.58
    methyl acetate 131.07
    THF 570.31
    2-butanone 221.1
    n-pentanol 77.6
    sec-butanol 74.66
    n-hexane 0.96
    ethylene glycol 18.38
    NMP 91.68
    cyclohexane 5.61
    DMSO 135.13
    n-butyl acetate 112.87
    n-octanol 36.29
    chloroform 932.28
    n-propyl acetate 104.77
    acetic acid 105.12
    dichloromethane 629.17
    cyclohexanone 275.45
    propylene glycol 41.34
    isopropyl acetate 129.65
    DMAc 306.58
    2-ethoxyethanol 182.33
    isopentanol 129.51
    n-heptane 2.1
    ethyl formate 102.09
    1,2-dichloroethane 293.34
    n-hexanol 83.04
    2-methoxyethanol 302.86
    isobutyl acetate 102.19
    tetrachloromethane 54.94
    n-pentyl acetate 88.12
    transcutol 602.7
    n-heptanol 51.87
    ethylbenzene 47.61
    MIBK 124.72
    2-propoxyethanol 227.14
    tert-butanol 103.38
    MTBE 103.97
    2-butoxyethanol 138.81
    propionic acid 61.79
    o-xylene 67.55
    formic acid 43.98
    diethyl ether 99.96
    m-xylene 92.71
    p-xylene 75.44
    chlorobenzene 202.65
    dimethyl carbonate 81.73
    n-octane 1.37
    formamide 69.87
    cyclopentanone 268.07
    2-pentanone 181.14
    anisole 124.54
    cyclopentyl methyl ether 141.99
    gamma-butyrolactone 211.62
    1-methoxy-2-propanol 233.7
    pyridine 273.39
    3-pentanone 129.4
    furfural 230.67
    n-dodecane 1.73
    diethylene glycol 167.15
    diisopropyl ether 23.29
    tert-amyl alcohol 72.98
    acetylacetone 220.18
    n-hexadecane 2.1
    acetophenone 126.07
    methyl propionate 133.86
    isopentyl acetate 130.79
    trichloroethylene 680.41
    n-nonanol 38.79
    cyclohexanol 97.69
    benzyl alcohol 133.19
    2-ethylhexanol 47.9
    isooctanol 47.45
    dipropyl ether 41.54
    1,2-dichlorobenzene 155.31
    ethyl lactate 66.01
    propylene carbonate 159.82
    n-methylformamide 74.88
    2-pentanol 65.18
    n-pentane 1.43
    1-propoxy-2-propanol 142.03
    1-methoxy-2-propyl acetate 171.79
    2-(2-methoxypropoxy) propanol 123.9
    mesitylene 39.82
    ε-caprolactone 187.09
    p-cymene 30.91
    epichlorohydrin 400.46
    1,1,1-trichloroethane 247.46
    2-aminoethanol 56.97
    morpholine-4-carbaldehyde 207.75
    sulfolane 174.75
    2,2,4-trimethylpentane 2.72
    2-methyltetrahydrofuran 202.54
    n-hexyl acetate 88.44
    isooctane 2.39
    2-(2-butoxyethoxy)ethanol 177.99
    sec-butyl acetate 85.9
    tert-butyl acetate 119.28
    decalin 3.75
    glycerin 68.31
    diglyme 320.63
    acrylic acid 59.14
    isopropyl myristate 40.09
    n-butyric acid 155.36
    acetyl acetate 112.77
    di(2-ethylhexyl) phthalate 57.46
    ethyl propionate 83.19
    nitromethane 151.74
    1,2-diethoxyethane 165.54
    benzonitrile 133.81
    trioctyl phosphate 36.07
    1-bromopropane 112.21
    gamma-valerolactone 362.86
    n-decanol 28.69
    triethyl phosphate 47.11
    4-methyl-2-pentanol 51.77
    propionitrile 80.58
    vinylene carbonate 162.13
    1,1,2-trichlorotrifluoroethane 239.96
    DMS 89.41
    cumene 30.27
    2-octanol 32.53
    2-hexanone 109.41
    octyl acetate 50.77
    limonene 37.45
    1,2-dimethoxyethane 256.54
    ethyl orthosilicate 47.53
    tributyl phosphate 41.24
    diacetone alcohol 140.15
    N,N-dimethylaniline 72.48
    acrylonitrile 93.2
    aniline 178.99
    1,3-propanediol 131.93
    bromobenzene 218.1
    dibromomethane 335.18
    1,1,2,2-tetrachloroethane 480.97
    2-methyl-cyclohexyl acetate 82.98
    tetrabutyl urea 54.19
    diisobutyl methanol 30.15
    2-phenylethanol 125.57
    styrene 67.35
    dioctyl adipate 63.76
    dimethyl sulfate 102.73
    ethyl butyrate 84.25
    methyl lactate 81.29
    butyl lactate 81.04
    diethyl carbonate 61.01
    propanediol butyl ether 108.01
    triethyl orthoformate 69.37
    p-tert-butyltoluene 29.36
    methyl 4-tert-butylbenzoate 98.81
    morpholine 302.69
    tert-butylamine 44.0
    n-dodecanol 21.45
    dimethoxymethane 280.33
    ethylene carbonate 147.3
    cyrene 120.11
    2-ethoxyethyl acetate 153.37
    2-ethylhexyl acetate 93.6
    1,2,4-trichlorobenzene 179.01
    4-methylpyridine 276.95
    dibutyl ether 40.26
    2,6-dimethyl-4-heptanol 30.15
    DEF 123.99
    dimethyl isosorbide 203.09
    tetrachloroethylene 271.6
    eugenol 109.36
    triacetin 112.15
    span 80 94.63
    1,4-butanediol 50.92
    1,1-dichloroethane 333.15
    2-methyl-1-pentanol 85.21
    methyl formate 74.82
    2-methyl-1-butanol 99.24
    n-decane 2.84
    butyronitrile 101.14
    3,7-dimethyl-1-octanol 44.53
    1-chlorooctane 20.18
    1-chlorotetradecane 8.07
    n-nonane 2.15
    undecane 2.14
    tert-butylcyclohexane 3.38
    cyclooctane 1.76
    cyclopentanol 82.91
    tetrahydropyran 264.65
    tert-amyl methyl ether 66.95
    2,5,8-trioxanonane 212.56
    1-hexene 9.92
    2-isopropoxyethanol 134.27
    2,2,2-trifluoroethanol 54.61
    methyl butyrate 111.33

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction