Hydroxypropyl bisisostearamidopropyldimonium chloride

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  • Identifiers

    CAS number
    111381-09-0

    Molecular formula
    C49H102Cl2N4O3

    SMILES
    CC(C)CCCCCCCCCCCCCCC(=O)NCCC[N+](C)(C)CC(C[N+](C)(C)CCCNC(=O)CCCCCCCCCCCCCCC(C)C)O.[Cl-].[Cl-]

    Safety labels

  • Odor profile

    Fragrance
    Waxy 40.36%
    Woody 34.33%
    Savory 31.07%
    Cooling 30.8%
    Animal 30.06%
    Fishy 29.9%
    Meaty 28.96%
    Odorless 28.02%
    Fatty 27.91%
    Mint 25.74%

     

    Flavor
    Bland 39.05%
    Mild 29.12%
    Odorless 25.78%
    Faint 22.09%
    Delicate 20.97%
    Slightly waxy 20.63%
    Cedarleaf 19.18%
    Bay oil 19.16%
    Yeasty 19.09%
    Diterpene 18.96%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    9.26 (weak base)

    Molecular weight
    866.3 g/mol

    Flash point

    • 143.58 ˚C est.

  • Synonyms

    • 4S9XCQ248I
    • Hydroxypropyl bisisostearamidopropyldimonium chloride
    • UNII-4S9XCQ248I
    • 111381-09-0
    • 1,3-Propanediaminium, 2-hydroxy-N,N,N',N'-tetramethyl-N,N'-bis(3-((1-oxoisooctadecyl)amino)propyl)-, dichloride
    • Hydroxypropyl bisisostearamidopropyldimonium chloride [INCI]
    • BIS(ISOSTEARAMIDOPROPYLDIMONIUM) HYDROXYPROPYL CHLORIDE
    • RefChem:147264
    • DTXSID901021373
    • Q27260421
    • 111381-09-0

  • Applications

    Hydroxypropyl bisisostearamidopropyldimonium chloride (CAS 111381-09-0) is a cationic surfactant commonly used as a conditioning agent in cosmetics and personal care, helping to soften hair, reduce static, and improve slip. In hair and skin formulations it often serves as a conditioning emulsifier. Because of its surfactant properties, it is considered for household and industrial cleaning products as a surface-active additive, and it can function as a fabric conditioning agent in laundry formulations. In polymer coatings and inks, it can act as a surfactant to improve dispersion and wetting, and some agricultural formulations may use it as an adjuvant to improve spray performance, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 16.67
    methanol 24.52
    isopropanol 7.86
    water 0.5
    ethyl acetate 23.9
    n-propanol 19.55
    acetone 23.03
    n-butanol 15.79
    acetonitrile 5.18
    DMF 57.84
    toluene 18.34
    isobutanol 14.01
    1,4-dioxane 29.3
    methyl acetate 21.5
    THF 97.93
    2-butanone 36.77
    n-pentanol 15.91
    sec-butanol 14.97
    n-hexane 1.92
    ethylene glycol 2.54
    NMP 244.69
    cyclohexane 3.02
    DMSO 47.66
    n-butyl acetate 23.55
    n-octanol 11.65
    chloroform 110.04
    n-propyl acetate 27.08
    acetic acid 73.22
    dichloromethane 85.78
    cyclohexanone 93.38
    propylene glycol 7.78
    isopropyl acetate 20.67
    DMAc 140.85
    2-ethoxyethanol 37.88
    isopentanol 12.6
    n-heptane 1.76
    ethyl formate 23.5
    1,2-dichloroethane 41.94
    n-hexanol 11.29
    2-methoxyethanol 38.64
    isobutyl acetate 20.06
    tetrachloromethane 20.47
    n-pentyl acetate 39.25
    transcutol 97.31
    n-heptanol 15.03
    ethylbenzene 8.66
    MIBK 20.05
    2-propoxyethanol 37.38
    tert-butanol 7.42
    MTBE 12.79
    2-butoxyethanol 49.74
    propionic acid 33.57
    o-xylene 12.81
    formic acid 33.17
    diethyl ether 11.25
    m-xylene 11.53
    p-xylene 10.85
    chlorobenzene 26.95
    dimethyl carbonate 17.88
    n-octane 0.85
    formamide 32.92
    cyclopentanone 113.68
    2-pentanone 29.13
    anisole 16.33
    cyclopentyl methyl ether 51.86
    gamma-butyrolactone 127.99
    1-methoxy-2-propanol 32.97
    pyridine 54.51
    3-pentanone 27.86
    furfural 106.98
    n-dodecane 0.39
    diethylene glycol 15.13
    diisopropyl ether 4.09
    tert-amyl alcohol 16.6
    acetylacetone 37.12
    n-hexadecane 0.45
    acetophenone 32.23
    methyl propionate 30.88
    isopentyl acetate 24.07
    trichloroethylene 113.54
    n-nonanol 12.1
    cyclohexanol 25.89
    benzyl alcohol 21.72
    2-ethylhexanol 10.0
    isooctanol 13.02
    dipropyl ether 12.96
    1,2-dichlorobenzene 27.37
    ethyl lactate 22.31
    propylene carbonate 71.93
    n-methylformamide 35.4
    2-pentanol 10.0
    n-pentane 1.59
    1-propoxy-2-propanol 32.76
    1-methoxy-2-propyl acetate 37.97
    2-(2-methoxypropoxy) propanol 35.04
    mesitylene 6.03
    ε-caprolactone 106.97
    p-cymene 6.69
    epichlorohydrin 106.43
    1,1,1-trichloroethane 40.29
    2-aminoethanol 10.42
    morpholine-4-carbaldehyde 107.0
    sulfolane 201.14
    2,2,4-trimethylpentane 1.6
    2-methyltetrahydrofuran 66.6
    n-hexyl acetate 34.69
    isooctane 0.61
    2-(2-butoxyethoxy)ethanol 43.14
    sec-butyl acetate 20.43
    tert-butyl acetate 25.78
    decalin 1.95
    glycerin 14.55
    diglyme 85.23
    acrylic acid 32.83
    isopropyl myristate 7.89
    n-butyric acid 49.99
    acetyl acetate 20.59
    di(2-ethylhexyl) phthalate 14.64
    ethyl propionate 22.59
    nitromethane 62.89
    1,2-diethoxyethane 22.68
    benzonitrile 15.84
    trioctyl phosphate 9.83
    1-bromopropane 22.56
    gamma-valerolactone 174.42
    n-decanol 6.46
    triethyl phosphate 18.17
    4-methyl-2-pentanol 6.82
    propionitrile 7.95
    vinylene carbonate 61.77
    1,1,2-trichlorotrifluoroethane 137.18
    DMS 21.17
    cumene 6.43
    2-octanol 9.14
    2-hexanone 27.8
    octyl acetate 13.3
    limonene 10.25
    1,2-dimethoxyethane 44.96
    ethyl orthosilicate 17.93
    tributyl phosphate 11.35
    diacetone alcohol 36.97
    N,N-dimethylaniline 15.42
    acrylonitrile 10.65
    aniline 24.54
    1,3-propanediol 15.02
    bromobenzene 25.59
    dibromomethane 50.49
    1,1,2,2-tetrachloroethane 98.86
    2-methyl-cyclohexyl acetate 27.41
    tetrabutyl urea 16.91
    diisobutyl methanol 4.53
    2-phenylethanol 17.98
    styrene 9.29
    dioctyl adipate 17.88
    dimethyl sulfate 50.9
    ethyl butyrate 26.13
    methyl lactate 26.43
    butyl lactate 39.7
    diethyl carbonate 15.16
    propanediol butyl ether 35.24
    triethyl orthoformate 25.86
    p-tert-butyltoluene 6.16
    methyl 4-tert-butylbenzoate 46.24
    morpholine 57.45
    tert-butylamine 4.54
    n-dodecanol 3.54
    dimethoxymethane 34.22
    ethylene carbonate 47.87
    cyrene 61.11
    2-ethoxyethyl acetate 52.85
    2-ethylhexyl acetate 22.08
    1,2,4-trichlorobenzene 42.46
    4-methylpyridine 45.95
    dibutyl ether 9.88
    2,6-dimethyl-4-heptanol 4.53
    DEF 50.32
    dimethyl isosorbide 62.38
    tetrachloroethylene 67.62
    eugenol 36.58
    triacetin 52.03
    span 80 34.38
    1,4-butanediol 7.77
    1,1-dichloroethane 31.11
    2-methyl-1-pentanol 15.52
    methyl formate 28.63
    2-methyl-1-butanol 18.04
    n-decane 1.08
    butyronitrile 9.71
    3,7-dimethyl-1-octanol 9.57
    1-chlorooctane 6.98
    1-chlorotetradecane 1.53
    n-nonane 1.01
    undecane 0.6
    tert-butylcyclohexane 1.65
    cyclooctane 1.24
    cyclopentanol 31.39
    tetrahydropyran 42.72
    tert-amyl methyl ether 18.54
    2,5,8-trioxanonane 42.77
    1-hexene 6.7
    2-isopropoxyethanol 26.93
    2,2,2-trifluoroethanol 37.37
    methyl butyrate 35.31

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction