Hydrogen Bromide

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  • Identifiers

    CAS number
    10035-10-6

    Molecular formula
    BrH

    SMILES
    Br

    Safety labels

    Compressed Gas
    Compressed Gas

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Odor impact est.
    Medium

    Odor threshold

    • Odor Threshold Low: 2.0 [ppm]. Odor threshold from CHEMINFO
    • The odor threshold is 26.6 ppm.
    • Odor threshold= 6.6667 mg/cu m. Irritating concentration= 10.00 mg/cu m.

  • Properties

    XLogP3-AA
    1.0

    pKa est.
    -55.39 (strong acid)

    Molecular weight
    80.91 g/mol

    Melting point expt.

    • -124 °F (NIOSH, 2024)
    • -86.80 °C
    • -87 °C
    • -124 °F

    Boiling point

    • -88.2 °F at 760 mmHg (USCG, 1999)
    • -66.38 °C
    • -67 °C
    • -88.2 °F
    • -88 °F

    Flash point

    • 34.03 ˚C est.

    Solubility expt.

    • 49 % (NIOSH, 2024)
    • 221 g/100 cc water at 0 °C; 130 g/100 cc water at 100 °C
    • Freely soluble in water; 1 volume of water dissolves 600 volumes of HBr at 0 °C
    • 204.0 g/ 100 g water at 15 °C
    • Very soluble in water
    • For more Solubility (Complete) data for Hydrogen bromide (6 total), please visit the HSDB record page.
    • Solubility in water, g/100ml at 20 °C: 193
    • 49%

  • Synonyms

    • Hydrogen bromide
    • HYDROBROMIC ACID
    • 10035-10-6
    • bromane
    • Bromwasserstoff
    • Broomwaterstof
    • Bromowodor
    • Acido bromidrico
    • Acide bromhydrique
    • Hydrogen bromide (HBr)
    • Anhydrous hydrobromic acid
    • Hydrogen bromide, anhydrous
    • Acido bromhidrico
    • Hydrogen monobromide
    • 3IY7CNP8XJ
    • Bromure d'hydrogene anhydre
    • Bromuro de hidrogeno anhidro
    • bromure d'hydrogene
    • CHEBI:47266
    • DTXSID0029713
    • NSC-606640
    • Hydrogenbromid
    • Anhydrous hydrogen bromide
    • bromidohydrogen
    • Acid, Hydrobromic
    • Bromide, Hydrogen
    • Hydrobromicum Acidum
    • Aqueous hydrogen bromide
    • RefChem:57367
    • Hydrogen bromide (HBr2)
    • DTXCID809713
    • 233-113-0
    • hydrogenbromide
    • MFCD00011323
    • Bromowodor [Polish]
    • Broomwaterstof [Dutch]
    • Bromwasserstoff [German]
    • Hydrobromic acid, ACS reagent, 48%
    • Acido bromidrico [Italian]
    • Acide bromhydrique [French]
    • Acido bromhidrico [Spanish]
    • HSDB 570
    • Hydrobromic acid,48%
    • Hydrobromic Acid (47-48% in aqueous solution)
    • EINECS 233-113-0
    • UNII-3IY7CNP8XJ
    • Bromure d'hydrogene anhydre [French]
    • UN1048
    • UN1788
    • Bromuro de hidrogeno anhidro [Spanish]
    • bromohydride
    • bromum
    • hydrobromid
    • organobromide
    • organobromides
    • hydro bromide
    • hydrobromic aicd
    • hydrogen-bromide
    • hyrdogen bromide
    • hydrobrornic acid
    • Bromohydric Acid; Hydrogen Bromide; Hydrogen Monobromide; NSC 606640
    • hydro-bromic acid
    • bromoorganic compound
    • organobromide compound
    • organobromine compound
    • organobromide compounds
    • organobromine compounds
    • BROMOHYDRIC ACID
    • HYDROGENE BROMIDE
    • an organobromine molecule
    • Hydrobromic acid, 48%
    • 3,4-bis-(benzyloxy)-
    • Hydrobromic acid 62% by weight or more HBr
    • SCHEMBL183
    • 35Br
    • EC 233-113-0
    • hydrogen bromide 33% w/w
    • Hydrogen bromide, anhydrous-
    • HYDROBROMIC ACID [MI]
    • HYDROBROMIC ACID 10%
    • HYDROGEN BROMIDE [MI]
    • Hydrogen bromide in acetic acid
    • SCHEMBL1872791
    • HYDROBROMIC ACID [HSDB]
    • CHEMBL1231461
    • CHEBI:37141
    • Hydrobromic acid - 48% in water
    • Hydrogen Bromide - Ethanol Reagent
    • Hydrogen Bromide - Methanol Reagent
    • BDBM50499189
    • AKOS015833690
    • Hydrobromic acid, reagent grade, 48%
    • FH47126
    • UN 1048
    • UN 1788
    • Hydrogen Bromide 33% wt in Acetic Acid
    • BP-21021
    • Hydrobromic acid,48%, ACS reagent grade
    • O-(isopropulamino)acetophenone hydrobromide
    • Hydrogen bromide, ReagentPlus(R), >=99%
    • H0182
    • H0959
    • H1220
    • NS00113695
    • Q2447
    • X0043
    • A800104
    • Hydrobromic acid, SAJ first grade, 45.0-49.0%
    • Hydrobromic acid, 48 wt. % in H2O, >=99.99%
    • Hydrobromic acid, JIS special grade, 47.0-49.0%
    • Hydrobromic acid, with more than 49% hydrobromic acid
    • Hydrogen bromide, anhydrous [UN1048] [Poison gas]
    • Hydrobromic acid, p.a., ACS reagent, reag. ISO, 47.0%
    • Hydrobromic acid, with not more than 49% hydrobromic acid
    • Hydrobromic acid, with more than 49% hydrobromic acid [UN1788] [Corrosive]
    • Hydrobromic acid, with not more than 49% hydrobromic acid [UN1788] [Corrosive]
    • 10035-10-6

  • Applications

    Hydrogen bromide (CAS 10035-10-6) is used as a reactive brominating agent and bromide source in organic synthesis: it converts alcohols to alkyl bromides and enables bromination of C=C bonds to form brominated intermediates for pharmaceutical and agrochemical precursors; it also provides hydrobromide salts of amines used in drug substances and formulations. Hydrobromic acid solutions are employed in industrial cleaning and metal surface descaling. Additionally, HBr serves as a bromide source for analytical and specialized process chemistry, including polymer-related and other high-value chemical transformations, with use subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 297.3
    methanol 410.87
    isopropanol 223.6
    water 49.97
    ethyl acetate 99.18
    n-propanol 200.95
    acetone 299.52
    n-butanol 179.87
    acetonitrile 146.59
    DMF 720.04
    toluene 47.82
    isobutanol 136.96
    1,4-dioxane 296.4
    methyl acetate 124.63
    THF 399.05
    2-butanone 151.52
    n-pentanol 130.51
    sec-butanol 159.19
    n-hexane 15.57
    ethylene glycol 197.18
    NMP 462.85
    cyclohexane 22.74
    DMSO 660.41
    n-butyl acetate 86.69
    n-octanol 80.34
    chloroform 143.47
    n-propyl acetate 78.98
    acetic acid 359.02
    dichloromethane 128.49
    cyclohexanone 185.03
    propylene glycol 137.81
    isopropyl acetate 63.06
    DMAc 412.09
    2-ethoxyethanol 215.25
    isopentanol 125.13
    n-heptane 21.05
    ethyl formate 103.13
    1,2-dichloroethane 104.74
    n-hexanol 116.02
    2-methoxyethanol 363.06
    isobutyl acetate 53.77
    tetrachloromethane 44.24
    n-pentyl acetate 76.84
    transcutol 335.65
    n-heptanol 83.87
    ethylbenzene 25.61
    MIBK 75.79
    2-propoxyethanol 200.57
    tert-butanol 226.54
    MTBE 121.37
    2-butoxyethanol 149.1
    propionic acid 173.87
    o-xylene 43.5
    formic acid 228.54
    diethyl ether 130.22
    m-xylene 39.09
    p-xylene 36.3
    chlorobenzene 67.79
    dimethyl carbonate 76.06
    n-octane 9.92
    formamide 256.7
    cyclopentanone 260.24
    2-pentanone 129.75
    anisole 78.29
    cyclopentyl methyl ether 151.01
    gamma-butyrolactone 254.1
    1-methoxy-2-propanol 245.5
    pyridine 184.91
    3-pentanone 96.67
    furfural 244.94
    n-dodecane 10.07
    diethylene glycol 238.94
    diisopropyl ether 41.09
    tert-amyl alcohol 152.78
    acetylacetone 133.97
    n-hexadecane 10.74
    acetophenone 78.73
    methyl propionate 105.05
    isopentyl acetate 70.37
    trichloroethylene 160.85
    n-nonanol 68.66
    cyclohexanol 141.31
    benzyl alcohol 88.98
    2-ethylhexanol 67.63
    isooctanol 65.22
    dipropyl ether 82.51
    1,2-dichlorobenzene 60.98
    ethyl lactate 60.31
    propylene carbonate 125.12
    n-methylformamide 279.11
    2-pentanol 117.45
    n-pentane 23.82
    1-propoxy-2-propanol 148.63
    1-methoxy-2-propyl acetate 87.31
    2-(2-methoxypropoxy) propanol 118.1
    mesitylene 29.24
    ε-caprolactone 149.1
    p-cymene 29.17
    epichlorohydrin 197.05
    1,1,1-trichloroethane 88.15
    2-aminoethanol 219.33
    morpholine-4-carbaldehyde 382.03
    sulfolane 334.58
    2,2,4-trimethylpentane 14.36
    2-methyltetrahydrofuran 219.64
    n-hexyl acetate 85.17
    isooctane 11.7
    2-(2-butoxyethoxy)ethanol 163.82
    sec-butyl acetate 49.27
    tert-butyl acetate 76.93
    decalin 11.82
    glycerin 220.82
    diglyme 265.62
    acrylic acid 187.37
    isopropyl myristate 42.72
    n-butyric acid 169.52
    acetyl acetate 69.85
    di(2-ethylhexyl) phthalate 52.55
    ethyl propionate 62.23
    nitromethane 324.95
    1,2-diethoxyethane 115.45
    benzonitrile 88.25
    trioctyl phosphate 43.46
    1-bromopropane 71.48
    gamma-valerolactone 298.63
    n-decanol 54.6
    triethyl phosphate 41.68
    4-methyl-2-pentanol 68.17
    propionitrile 110.07
    vinylene carbonate 121.84
    1,1,2-trichlorotrifluoroethane 206.86
    DMS 67.7
    cumene 23.55
    2-octanol 60.6
    2-hexanone 93.7
    octyl acetate 57.55
    limonene 46.42
    1,2-dimethoxyethane 250.27
    ethyl orthosilicate 42.84
    tributyl phosphate 44.57
    diacetone alcohol 124.1
    N,N-dimethylaniline 75.98
    acrylonitrile 134.54
    aniline 105.06
    1,3-propanediol 234.53
    bromobenzene 53.35
    dibromomethane 95.22
    1,1,2,2-tetrachloroethane 136.17
    2-methyl-cyclohexyl acetate 55.16
    tetrabutyl urea 68.63
    diisobutyl methanol 46.32
    2-phenylethanol 83.8
    styrene 36.01
    dioctyl adipate 61.05
    dimethyl sulfate 136.77
    ethyl butyrate 64.95
    methyl lactate 99.24
    butyl lactate 72.74
    diethyl carbonate 45.2
    propanediol butyl ether 138.96
    triethyl orthoformate 55.84
    p-tert-butyltoluene 31.03
    methyl 4-tert-butylbenzoate 95.18
    morpholine 322.48
    tert-butylamine 146.43
    n-dodecanol 46.03
    dimethoxymethane 262.62
    ethylene carbonate 97.6
    cyrene 116.09
    2-ethoxyethyl acetate 94.72
    2-ethylhexyl acetate 60.42
    1,2,4-trichlorobenzene 78.16
    4-methylpyridine 157.25
    dibutyl ether 61.58
    2,6-dimethyl-4-heptanol 46.32
    DEF 181.95
    dimethyl isosorbide 156.2
    tetrachloroethylene 112.39
    eugenol 109.12
    triacetin 83.94
    span 80 119.93
    1,4-butanediol 126.28
    1,1-dichloroethane 99.43
    2-methyl-1-pentanol 96.89
    methyl formate 197.73
    2-methyl-1-butanol 118.17
    n-decane 13.34
    butyronitrile 104.77
    3,7-dimethyl-1-octanol 60.41
    1-chlorooctane 36.86
    1-chlorotetradecane 20.64
    n-nonane 12.58
    undecane 11.34
    tert-butylcyclohexane 12.87
    cyclooctane 9.22
    cyclopentanol 186.45
    tetrahydropyran 208.37
    tert-amyl methyl ether 95.78
    2,5,8-trioxanonane 203.62
    1-hexene 45.0
    2-isopropoxyethanol 139.61
    2,2,2-trifluoroethanol 143.24
    methyl butyrate 85.85

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction