Guanidinium sulphate

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  • Identifiers

    CAS number
    1184-68-5

    Molecular formula
    C2H12N6O4S

    SMILES
    C(=[NH2+])(N)N.C(=[NH2+])(N)N.[O-]S(=O)(=O)[O-]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 57.46%
    Fishy 47.21%
    Cheesy 27.01%
    Pungent 26.58%
    Ripe 22.33%
    Meaty 17.54%
    Savory 15.91%
    Sulfurous 15.81%
    Cooked 15.79%
    Radish 13.9%

     

    Flavor
    Odorless 28.94%
    Mustard 22.06%
    Pungent 21.12%
    Mousy 20.54%
    Garlic 20.12%
    Formyl 19.96%
    Rotten 19.77%
    Sulfur 19.58%
    Bitter 19.23%
    Nitrile 19.12%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    12.57 (strong base)

    Molecular weight
    216.22 g/mol

    Flash point

    • 94.46 ˚C est.

  • Synonyms

    • Guanidinium sulphate
    • 1184-68-5
    • EINECS 214-674-0
    • diaminomethylideneazanium;sulfate
    • AKOS015917942
    • FG65037
    • NS00079985
    • NS00081547
    • 1184-68-5

  • Applications

    Guanidinium sulphate is primarily used as a source of guanidinium ions for salt formation and as a soluble reagent in chemical synthesis and formulation work. In protein chemistry, it is commonly evaluated as a chaotropic agent and denaturant, and may serve as a component of buffers or sample-preparation schemes in analytical workflows. As a soluble salt, it is used as an electrolyte or to adjust ionic strength in various analytical and industrial processes. It can also function as a precursor or intermediate for guanidinium-containing compounds in polymer, pharmaceutical, and specialty-chemical syntheses.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 60.04
    methanol 198.73
    isopropanol 26.9
    water 1213.18
    ethyl acetate 13.93
    n-propanol 30.17
    acetone 31.66
    n-butanol 16.61
    acetonitrile 20.15
    DMF 301.13
    toluene 1.44
    isobutanol 16.49
    1,4-dioxane 27.81
    methyl acetate 23.47
    THF 38.66
    2-butanone 15.71
    n-pentanol 11.55
    sec-butanol 14.8
    n-hexane 1.03
    ethylene glycol 208.73
    NMP 114.25
    cyclohexane 0.72
    DMSO 90.77
    n-butyl acetate 10.05
    n-octanol 5.28
    chloroform 3.67
    n-propyl acetate 10.51
    acetic acid 144.15
    dichloromethane 3.11
    cyclohexanone 13.67
    propylene glycol 131.68
    isopropyl acetate 8.1
    DMAc 173.74
    2-ethoxyethanol 64.46
    isopentanol 9.14
    n-heptane 1.13
    ethyl formate 30.11
    1,2-dichloroethane 2.47
    n-hexanol 11.96
    2-methoxyethanol 148.53
    isobutyl acetate 6.61
    tetrachloromethane 2.73
    n-pentyl acetate 6.31
    transcutol 36.05
    n-heptanol 8.6
    ethylbenzene 0.73
    MIBK 5.34
    2-propoxyethanol 65.43
    tert-butanol 17.24
    MTBE 6.99
    2-butoxyethanol 41.47
    propionic acid 67.42
    o-xylene 1.52
    formic acid 402.98
    diethyl ether 7.35
    m-xylene 1.43
    p-xylene 1.26
    chlorobenzene 1.38
    dimethyl carbonate 35.47
    n-octane 0.45
    formamide 252.19
    cyclopentanone 28.69
    2-pentanone 9.96
    anisole 4.0
    cyclopentyl methyl ether 11.98
    gamma-butyrolactone 49.51
    1-methoxy-2-propanol 76.4
    pyridine 11.26
    3-pentanone 8.69
    furfural 55.86
    n-dodecane 0.3
    diethylene glycol 115.14
    diisopropyl ether 2.15
    tert-amyl alcohol 12.27
    acetylacetone 16.02
    n-hexadecane 0.31
    acetophenone 5.99
    methyl propionate 23.93
    isopentyl acetate 6.29
    trichloroethylene 4.28
    n-nonanol 4.71
    cyclohexanol 9.02
    benzyl alcohol 8.17
    2-ethylhexanol 4.73
    isooctanol 5.03
    dipropyl ether 7.32
    1,2-dichlorobenzene 1.24
    ethyl lactate 26.3
    propylene carbonate 26.06
    n-methylformamide 174.72
    2-pentanol 7.95
    n-pentane 1.0
    1-propoxy-2-propanol 36.42
    1-methoxy-2-propyl acetate 17.6
    2-(2-methoxypropoxy) propanol 18.8
    mesitylene 0.99
    ε-caprolactone 18.36
    p-cymene 1.24
    epichlorohydrin 19.95
    1,1,1-trichloroethane 2.22
    2-aminoethanol 150.44
    morpholine-4-carbaldehyde 120.04
    sulfolane 52.49
    2,2,4-trimethylpentane 0.49
    2-methyltetrahydrofuran 13.47
    n-hexyl acetate 6.32
    isooctane 0.33
    2-(2-butoxyethoxy)ethanol 25.63
    sec-butyl acetate 5.03
    tert-butyl acetate 6.58
    decalin 0.37
    glycerin 268.46
    diglyme 50.19
    acrylic acid 98.04
    isopropyl myristate 2.14
    n-butyric acid 36.01
    acetyl acetate 11.65
    di(2-ethylhexyl) phthalate 5.12
    ethyl propionate 10.07
    nitromethane 141.74
    1,2-diethoxyethane 7.55
    benzonitrile 4.99
    trioctyl phosphate 4.36
    1-bromopropane 1.36
    gamma-valerolactone 62.34
    n-decanol 3.33
    triethyl phosphate 6.09
    4-methyl-2-pentanol 4.25
    propionitrile 11.23
    vinylene carbonate 27.45
    1,1,2-trichlorotrifluoroethane 69.61
    DMS 11.11
    cumene 0.81
    2-octanol 3.63
    2-hexanone 7.25
    octyl acetate 4.08
    limonene 1.71
    1,2-dimethoxyethane 54.7
    ethyl orthosilicate 5.47
    tributyl phosphate 4.58
    diacetone alcohol 15.87
    N,N-dimethylaniline 4.79
    acrylonitrile 21.73
    aniline 7.13
    1,3-propanediol 86.86
    bromobenzene 0.69
    dibromomethane 1.78
    1,1,2,2-tetrachloroethane 4.34
    2-methyl-cyclohexyl acetate 4.92
    tetrabutyl urea 7.2
    diisobutyl methanol 2.52
    2-phenylethanol 7.57
    styrene 0.92
    dioctyl adipate 4.43
    dimethyl sulfate 56.98
    ethyl butyrate 7.85
    methyl lactate 64.03
    butyl lactate 15.83
    diethyl carbonate 6.89
    propanediol butyl ether 37.64
    triethyl orthoformate 8.07
    p-tert-butyltoluene 1.31
    methyl 4-tert-butylbenzoate 10.95
    morpholine 40.07
    tert-butylamine 7.44
    n-dodecanol 2.46
    dimethoxymethane 76.57
    ethylene carbonate 21.86
    cyrene 26.15
    2-ethoxyethyl acetate 10.7
    2-ethylhexyl acetate 4.86
    1,2,4-trichlorobenzene 2.01
    4-methylpyridine 8.86
    dibutyl ether 2.7
    2,6-dimethyl-4-heptanol 2.52
    DEF 30.48
    dimethyl isosorbide 21.32
    tetrachloroethylene 5.13
    eugenol 17.37
    triacetin 12.02
    span 80 19.3
    1,4-butanediol 49.21
    1,1-dichloroethane 2.38
    2-methyl-1-pentanol 5.98
    methyl formate 132.12
    2-methyl-1-butanol 10.32
    n-decane 0.48
    butyronitrile 8.02
    3,7-dimethyl-1-octanol 2.98
    1-chlorooctane 1.0
    1-chlorotetradecane 0.52
    n-nonane 0.47
    undecane 0.36
    tert-butylcyclohexane 0.39
    cyclooctane 0.4
    cyclopentanol 19.52
    tetrahydropyran 10.05
    tert-amyl methyl ether 5.93
    2,5,8-trioxanonane 30.3
    1-hexene 1.93
    2-isopropoxyethanol 28.02
    2,2,2-trifluoroethanol 121.85
    methyl butyrate 14.06

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction