Guanidinium sulphate

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  • Identifiers

    CAS number
    1184-68-5

    Molecular formula
    C2H12N6O4S

    SMILES
    C(=[NH2+])(N)N.C(=[NH2+])(N)N.[O-]S(=O)(=O)[O-]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 81.68%
    Fishy 21.01%
    Pungent 20.7%
    Savory 15.07%
    Cooked 14.66%
    Cheesy 12.97%
    Sulfurous 12.66%
    Ripe 11.62%
    Meaty 11.04%
    Bitter 10.96%

     

    Flavor
    Odorless 41.02%
    Bitter 37.95%
    Mustard 22.72%
    Bland 21.68%
    Sulfur 21.24%
    Mousy 21.21%
    Formyl 21.08%
    Nitrile 20.47%
    Mild 20.01%
    Rotten 19.86%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    -203417.27 (strong acid)

    Molecular weight
    216.22 g/mol

    Flash point

    • 141.82 ˚C est.

  • Synonyms

    • Guanidinium sulphate
    • 1184-68-5
    • EINECS 214-674-0
    • diaminomethylideneazanium;sulfate
    • AKOS015917942
    • FG65037
    • NS00079985
    • NS00081547
    • 1184-68-5

  • Applications

    Guanidinium sulphate is primarily used as a source of guanidinium ions for salt formation and as a soluble reagent in chemical synthesis and formulation work. In protein chemistry, it is commonly evaluated as a chaotropic agent and denaturant, and may serve as a component of buffers or sample-preparation schemes in analytical workflows. As a soluble salt, it is used as an electrolyte or to adjust ionic strength in various analytical and industrial processes. It can also function as a precursor or intermediate for guanidinium-containing compounds in polymer, pharmaceutical, and specialty-chemical syntheses.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7.28
    methanol 27.01
    isopropanol 2.22
    water 164.81
    ethyl acetate 0.61
    n-propanol 2.96
    acetone 2.79
    n-butanol 1.53
    acetonitrile 1.86
    DMF 60.17
    toluene 0.16
    isobutanol 1.3
    1,4-dioxane 1.34
    methyl acetate 1.4
    THF 5.46
    2-butanone 1.32
    n-pentanol 0.85
    sec-butanol 1.08
    n-hexane 0.1
    ethylene glycol 28.18
    NMP 31.3
    cyclohexane 0.07
    DMSO 50.93
    n-butyl acetate 1.01
    n-octanol 0.33
    chloroform 0.31
    n-propyl acetate 0.83
    acetic acid 14.93
    dichloromethane 0.46
    cyclohexanone 1.14
    propylene glycol 18.26
    isopropyl acetate 0.36
    DMAc 35.76
    2-ethoxyethanol 11.82
    isopentanol 0.73
    n-heptane 0.12
    ethyl formate 3.39
    1,2-dichloroethane 0.34
    n-hexanol 0.99
    2-methoxyethanol 37.7
    isobutyl acetate 0.38
    tetrachloromethane 0.22
    n-pentyl acetate 0.49
    transcutol 5.44
    n-heptanol 0.75
    ethylbenzene 0.09
    MIBK 0.42
    2-propoxyethanol 12.68
    tert-butanol 1.36
    MTBE 0.3
    2-butoxyethanol 6.53
    propionic acid 5.81
    o-xylene 0.18
    formic acid 75.91
    diethyl ether 0.5
    m-xylene 0.14
    p-xylene 0.15
    chlorobenzene 0.08
    dimethyl carbonate 2.86
    n-octane 0.04
    formamide 75.32
    cyclopentanone 3.98
    2-pentanone 0.85
    anisole 0.28
    cyclopentyl methyl ether 1.11
    gamma-butyrolactone 8.24
    1-methoxy-2-propanol 13.75
    pyridine 1.29
    3-pentanone 0.69
    furfural 10.11
    n-dodecane 0.02
    diethylene glycol 23.13
    diisopropyl ether 0.11
    tert-amyl alcohol 0.87
    acetylacetone 1.14
    n-hexadecane 0.02
    acetophenone 0.6
    methyl propionate 1.59
    isopentyl acetate 0.57
    trichloroethylene 0.43
    n-nonanol 0.32
    cyclohexanol 0.56
    benzyl alcohol 0.67
    2-ethylhexanol 0.39
    isooctanol 0.4
    dipropyl ether 0.84
    1,2-dichlorobenzene 0.09
    ethyl lactate 3.27
    propylene carbonate 2.97
    n-methylformamide 35.43
    2-pentanol 0.54
    n-pentane 0.1
    1-propoxy-2-propanol 5.54
    1-methoxy-2-propyl acetate 1.93
    2-(2-methoxypropoxy) propanol 2.76
    mesitylene 0.11
    ε-caprolactone 1.59
    p-cymene 0.17
    epichlorohydrin 2.99
    1,1,1-trichloroethane 0.16
    2-aminoethanol 23.94
    morpholine-4-carbaldehyde 22.05
    sulfolane 16.03
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 1.2
    n-hexyl acetate 0.41
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 3.87
    sec-butyl acetate 0.3
    tert-butyl acetate 0.36
    decalin 0.03
    glycerin 55.04
    diglyme 8.64
    acrylic acid 10.51
    isopropyl myristate 0.14
    n-butyric acid 3.19
    acetyl acetate 0.42
    di(2-ethylhexyl) phthalate 0.48
    ethyl propionate 0.74
    nitromethane 17.74
    1,2-diethoxyethane 0.7
    benzonitrile 0.42
    trioctyl phosphate 0.39
    1-bromopropane 0.22
    gamma-valerolactone 10.2
    n-decanol 0.23
    triethyl phosphate 0.82
    4-methyl-2-pentanol 0.25
    propionitrile 1.1
    vinylene carbonate 2.89
    1,1,2-trichlorotrifluoroethane 12.27
    DMS 0.71
    cumene 0.09
    2-octanol 0.26
    2-hexanone 0.66
    octyl acetate 0.25
    limonene 0.18
    1,2-dimethoxyethane 8.16
    ethyl orthosilicate 0.69
    tributyl phosphate 0.4
    diacetone alcohol 1.85
    N,N-dimethylaniline 0.51
    acrylonitrile 2.42
    aniline 0.61
    1,3-propanediol 13.54
    bromobenzene 0.05
    dibromomethane 0.29
    1,1,2,2-tetrachloroethane 0.46
    2-methyl-cyclohexyl acetate 0.59
    tetrabutyl urea 0.89
    diisobutyl methanol 0.21
    2-phenylethanol 0.78
    styrene 0.08
    dioctyl adipate 0.31
    dimethyl sulfate 8.17
    ethyl butyrate 0.84
    methyl lactate 9.14
    butyl lactate 2.19
    diethyl carbonate 0.68
    propanediol butyl ether 4.78
    triethyl orthoformate 0.96
    p-tert-butyltoluene 0.16
    methyl 4-tert-butylbenzoate 1.12
    morpholine 3.38
    tert-butylamine 0.53
    n-dodecanol 0.16
    dimethoxymethane 10.8
    ethylene carbonate 1.83
    cyrene 5.54
    2-ethoxyethyl acetate 0.91
    2-ethylhexyl acetate 0.43
    1,2,4-trichlorobenzene 0.13
    4-methylpyridine 0.81
    dibutyl ether 0.19
    2,6-dimethyl-4-heptanol 0.21
    DEF 3.07
    dimethyl isosorbide 4.61
    tetrachloroethylene 0.5
    eugenol 2.32
    triacetin 1.01
    span 80 1.92
    1,4-butanediol 5.35
    1,1-dichloroethane 0.19
    2-methyl-1-pentanol 0.39
    methyl formate 21.87
    2-methyl-1-butanol 0.82
    n-decane 0.04
    butyronitrile 0.87
    3,7-dimethyl-1-octanol 0.17
    1-chlorooctane 0.07
    1-chlorotetradecane 0.04
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.02
    cyclooctane 0.04
    cyclopentanol 1.66
    tetrahydropyran 0.61
    tert-amyl methyl ether 0.37
    2,5,8-trioxanonane 5.16
    1-hexene 0.19
    2-isopropoxyethanol 3.38
    2,2,2-trifluoroethanol 14.05
    methyl butyrate 1.2

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction