Guaiacyl acetate

Overview IFRA Request a quote

  • Identifiers

    CAS number
    613-70-7

    Molecular formula
    C9H10O3

    SMILES
    CC(=O)OC1=CC=CC=C1OC

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 79.42%
    Vanilla 70.9%
    Phenolic 64.21%
    Spicy 61.22%
    Woody 60.41%
    Floral 58.05%
    Powdery 56.16%
    Balsamic 55.36%
    Clove 46.84%
    Fruity 44.92%

     

    Flavor
    Sweet 94.77%
    Woody 70.93%
    Powdery 54.18%
    Vanilla 52.67%
    Spice 49.43%
    Clove 46.02%
    Floral 42.02%
    Spicy 40.18%
    Creamy 39.51%
    Smoky 37.66%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    1.4

    pKa est.
    7.13 (neutral)

    Molecular weight
    166.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Melting point expt.

    • 31.5 °C

    Boiling point

    • 122.00 to 124.00 °C. @ 18.00 mm Hg

    Flash point

    • 100.41 ˚C est.

    Solubility expt.

    • insoluble to slightly soluble in water
    • miscible (in ethanol)

  • Synonyms

    • 2-Methoxyphenyl acetate
    • 613-70-7
    • Guaiacyl acetate
    • Guaiacol acetate
    • 15212-03-0
    • 1-Acetoxy-2-methoxybenzene
    • Phenol, 2-methoxy-, acetate
    • o-Acetoxyanisole
    • o-Anisyl acetate
    • (2-methoxyphenyl) acetate
    • Acetic Acid 2-Methoxyphenyl Ester
    • Acetyl guaiacol
    • o-METHOXYPHENYL ACETATE
    • Phenol, o-methoxy-, acetate
    • O-Acetylguaiacol
    • 2-acetoxyanisole
    • Phenol, 2-methoxy-, 1-acetate
    • Guaicyl acetate
    • Eucol (VAN)
    • FEMA No. 3687
    • NSC 3831
    • K5YN7743HC
    • NSC-3831
    • EINECS 210-350-8
    • AI3-10032
    • GUAIACYL ACETATE [FHFI]
    • DTXSID80862289
    • (MU)-METHOXYPHENYL ACETATE
    • Phenol, o-methoxy-, acetate (8CI)
    • 2-METHOXYPHENYLACETATE
    • UNII-K5YN7743HC
    • FEMA 3687
    • 2-Guaiacol Acetate
    • MFCD00017221
    • bmse010104
    • 1-acetoxy-2-methoxy-benzene
    • Acetic Acid 2-Guaiacol Ester
    • SCHEMBL236191
    • 2-Methoxyphenyl acetate, 98%
    • DTXCID40811076
    • NSC3831
    • CHEBI:193709
    • QAA21203
    • AKOS015889747
    • 2-Methoxyphenyl acetate, >=98%, FG
    • FA70968
    • Guaiacol acetate;2-Methoxyphenyl acetate
    • AS-59249
    • DB-043128
    • A1381
    • CS-0068376
    • NS00012507
    • N10380
    • Q27281996
    • 210-350-8

  • Applications

    Guaiacyl acetate (CAS 613-70-7) is primarily used as an intermediate in the synthesis of fragrance compounds and as an odorant ingredient in perfumery and cosmetic formulations, contributing woody, guaiac-like notes. It is commonly evaluated for use as a fragrance additive in household products and cleaning agents to enhance longevity of aroma. In industry, it may serve as a building block for more complex aroma-related molecules in coatings/inks and polymer-related syntheses. Its exact usage and permissible levels depend on local regulations and formulation constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 299.9
    methanol 485.33
    isopropanol 187.32
    water 4.19
    ethyl acetate 331.7
    n-propanol 182.79
    acetone 610.82
    n-butanol 143.44
    acetonitrile 573.35
    DMF 770.99
    toluene 150.18
    isobutanol 128.23
    1,4-dioxane 708.32
    methyl acetate 465.86
    THF 645.56
    2-butanone 350.07
    n-pentanol 120.06
    sec-butanol 158.1
    n-hexane 28.15
    ethylene glycol 169.09
    NMP 588.48
    cyclohexane 80.58
    DMSO 969.72
    n-butyl acetate 185.68
    n-octanol 102.69
    chloroform 827.24
    n-propyl acetate 220.39
    acetic acid 366.1
    dichloromethane 1286.41
    cyclohexanone 411.24
    propylene glycol 89.48
    isopropyl acetate 139.92
    DMAc 708.66
    2-ethoxyethanol 288.74
    isopentanol 110.46
    n-heptane 35.61
    ethyl formate 370.04
    1,2-dichloroethane 696.04
    n-hexanol 121.42
    2-methoxyethanol 475.88
    isobutyl acetate 113.66
    tetrachloromethane 113.74
    n-pentyl acetate 110.54
    transcutol 387.88
    n-heptanol 68.85
    ethylbenzene 124.28
    MIBK 114.02
    2-propoxyethanol 237.03
    tert-butanol 258.6
    MTBE 185.83
    2-butoxyethanol 122.46
    propionic acid 218.91
    o-xylene 134.62
    formic acid 155.4
    diethyl ether 252.25
    m-xylene 111.42
    p-xylene 172.46
    chlorobenzene 241.55
    dimethyl carbonate 214.93
    n-octane 20.01
    formamide 320.77
    cyclopentanone 495.45
    2-pentanone 221.91
    anisole 266.75
    cyclopentyl methyl ether 202.44
    gamma-butyrolactone 643.84
    1-methoxy-2-propanol 248.58
    pyridine 413.5
    3-pentanone 217.82
    furfural 592.1
    n-dodecane 22.2
    diethylene glycol 254.5
    diisopropyl ether 59.2
    tert-amyl alcohol 190.29
    acetylacetone 316.96
    n-hexadecane 24.73
    acetophenone 244.03
    methyl propionate 311.05
    isopentyl acetate 132.02
    trichloroethylene 958.82
    n-nonanol 89.86
    cyclohexanol 166.59
    benzyl alcohol 180.85
    2-ethylhexanol 91.67
    isooctanol 57.83
    dipropyl ether 145.95
    1,2-dichlorobenzene 247.52
    ethyl lactate 127.07
    propylene carbonate 334.06
    n-methylformamide 421.37
    2-pentanol 86.72
    n-pentane 29.43
    1-propoxy-2-propanol 147.36
    1-methoxy-2-propyl acetate 172.29
    2-(2-methoxypropoxy) propanol 154.83
    mesitylene 73.4
    ε-caprolactone 340.34
    p-cymene 75.93
    epichlorohydrin 729.27
    1,1,1-trichloroethane 455.14
    2-aminoethanol 163.89
    morpholine-4-carbaldehyde 572.98
    sulfolane 667.59
    2,2,4-trimethylpentane 16.39
    2-methyltetrahydrofuran 349.03
    n-hexyl acetate 172.26
    isooctane 10.54
    2-(2-butoxyethoxy)ethanol 185.05
    sec-butyl acetate 119.04
    tert-butyl acetate 144.48
    decalin 37.05
    glycerin 144.95
    diglyme 408.89
    acrylic acid 227.69
    isopropyl myristate 86.13
    n-butyric acid 212.88
    acetyl acetate 236.86
    di(2-ethylhexyl) phthalate 81.65
    ethyl propionate 215.27
    nitromethane 738.64
    1,2-diethoxyethane 202.45
    benzonitrile 256.74
    trioctyl phosphate 65.03
    1-bromopropane 288.85
    gamma-valerolactone 519.02
    n-decanol 73.98
    triethyl phosphate 113.3
    4-methyl-2-pentanol 49.62
    propionitrile 321.89
    vinylene carbonate 393.87
    1,1,2-trichlorotrifluoroethane 366.1
    DMS 206.46
    cumene 86.54
    2-octanol 59.88
    2-hexanone 183.46
    octyl acetate 113.23
    limonene 100.2
    1,2-dimethoxyethane 659.06
    ethyl orthosilicate 98.22
    tributyl phosphate 80.62
    diacetone alcohol 159.24
    N,N-dimethylaniline 181.25
    acrylonitrile 433.75
    aniline 172.08
    1,3-propanediol 194.08
    bromobenzene 273.07
    dibromomethane 718.09
    1,1,2,2-tetrachloroethane 661.73
    2-methyl-cyclohexyl acetate 137.24
    tetrabutyl urea 113.39
    diisobutyl methanol 57.15
    2-phenylethanol 142.51
    styrene 159.57
    dioctyl adipate 132.92
    dimethyl sulfate 316.45
    ethyl butyrate 202.26
    methyl lactate 155.38
    butyl lactate 88.38
    diethyl carbonate 182.24
    propanediol butyl ether 113.93
    triethyl orthoformate 133.22
    p-tert-butyltoluene 71.24
    methyl 4-tert-butylbenzoate 163.64
    morpholine 542.76
    tert-butylamine 150.77
    n-dodecanol 62.67
    dimethoxymethane 486.27
    ethylene carbonate 324.42
    cyrene 179.2
    2-ethoxyethyl acetate 159.52
    2-ethylhexyl acetate 109.74
    1,2,4-trichlorobenzene 265.3
    4-methylpyridine 351.86
    dibutyl ether 129.86
    2,6-dimethyl-4-heptanol 57.15
    DEF 346.16
    dimethyl isosorbide 256.12
    tetrachloroethylene 413.82
    eugenol 161.91
    triacetin 192.79
    span 80 117.36
    1,4-butanediol 104.16
    1,1-dichloroethane 516.51
    2-methyl-1-pentanol 103.37
    methyl formate 481.79
    2-methyl-1-butanol 110.13
    n-decane 30.47
    butyronitrile 264.7
    3,7-dimethyl-1-octanol 90.21
    1-chlorooctane 91.99
    1-chlorotetradecane 48.56
    n-nonane 30.43
    undecane 25.2
    tert-butylcyclohexane 29.96
    cyclooctane 23.57
    cyclopentanol 197.85
    tetrahydropyran 382.11
    tert-amyl methyl ether 141.79
    2,5,8-trioxanonane 299.77
    1-hexene 84.9
    2-isopropoxyethanol 178.38
    2,2,2-trifluoroethanol 170.07
    methyl butyrate 299.64

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction