Guaia-6,9-diene

Overview IFRA Request a quote

  • Identifiers

    Molecular formula
    C15H24

    SMILES
    CC1CCC2C1C=C(CC=C2C)C(C)C

  • Odor profile

    Fragrance
    Woody 81.76%
    Spicy 69.63%
    Herbal 65.73%
    Fresh 49.96%
    Citrus 45.71%
    Terpenic 44.82%
    Green 43.43%
    Dry 37.25%
    Pine 36.57%
    Balsamic 35.75%

     

    Flavor
    Woody 76.11%
    Herbal 63.81%
    Wood 63.08%
    Spice 55.03%
    Herb 51.73%
    Terpene 46.2%
    Citrus 43.27%
    Green 43.07%
    Turpentine 39.76%
    Lemon 33.83%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    4.3

    pKa est.
    9.47 (weak base)

    Molecular weight
    204.35 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    263°C

    Flash point

    • 81.94 ˚C est.

  • Synonyms

    • Guaia-6,9-diene
    • (1xi,4xi,5xi)-guaia-6,9-diene
    • 1,4-dimethyl-7-propan-2-yl-1,2,3,3a,6,8a-hexahydroazulene
    • Guaja-6,9-diene
    • CHEBI:49206
    • RCMUGHFHXFHKNW-UHFFFAOYSA-N
    • Guaia-6,9-diene, 1S,2R,5S
    • Q27121530
    • 7-isopropyl-1,4-dimethyl-1,2,3,3a,6,8a-hexahydroazulene
    • 1,4-dimethyl-7-(propan-2-yl)-1,2,3,3a,6,8a-hexahydroazulene

  • Applications

    Guaia-6,9-diene is a sesquiterpene widely used as a fragrance ingredient and fixative in perfumery, helping to preserve and stabilize wood- and terpene-like notes; it is also employed as a fragrance component in cosmetics and personal care products; in household and cleaning formulations, it may serve as a fragrance additive to impart a pleasant scent; in fragrance chemistry and industrial manufacturing, it is often used as an intermediate for the synthesis of other fragrance compounds; and in coatings, paints, inks, and related finishes, it can be added to impart or enhance a fragrance profile.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 101.72
    methanol 35.39
    isopropanol 139.91
    water 0.07
    ethyl acetate 314.8
    n-propanol 141.43
    acetone 271.6
    n-butanol 190.35
    acetonitrile 144.16
    DMF 192.47
    toluene 654.2
    isobutanol 142.96
    1,4-dioxane 704.17
    methyl acetate 248.7
    THF 1151.34
    2-butanone 378.44
    n-pentanol 145.4
    sec-butanol 169.34
    n-hexane 170.56
    ethylene glycol 8.59
    NMP 263.06
    cyclohexane 352.51
    DMSO 149.2
    n-butyl acetate 607.21
    n-octanol 216.87
    chloroform 913.31
    n-propyl acetate 241.71
    acetic acid 61.89
    dichloromethane 792.29
    cyclohexanone 600.47
    propylene glycol 24.73
    isopropyl acetate 283.3
    DMAc 238.95
    2-ethoxyethanol 116.95
    isopentanol 205.72
    n-heptane 302.25
    ethyl formate 137.01
    1,2-dichloroethane 440.34
    n-hexanol 358.55
    2-methoxyethanol 126.97
    isobutyl acetate 233.75
    tetrachloromethane 237.11
    n-pentyl acetate 331.2
    transcutol 599.16
    n-heptanol 198.67
    ethylbenzene 338.56
    MIBK 274.45
    2-propoxyethanol 284.26
    tert-butanol 217.53
    MTBE 418.93
    2-butoxyethanol 202.82
    propionic acid 82.14
    o-xylene 347.79
    formic acid 6.44
    diethyl ether 413.95
    m-xylene 416.44
    p-xylene 405.95
    chlorobenzene 461.55
    dimethyl carbonate 84.35
    n-octane 103.71
    formamide 16.05
    cyclopentanone 634.23
    2-pentanone 336.41
    anisole 381.55
    cyclopentyl methyl ether 544.37
    gamma-butyrolactone 418.87
    1-methoxy-2-propanol 160.56
    pyridine 676.21
    3-pentanone 289.07
    furfural 313.19
    n-dodecane 72.42
    diethylene glycol 104.07
    diisopropyl ether 202.98
    tert-amyl alcohol 205.25
    acetylacetone 322.99
    n-hexadecane 84.64
    acetophenone 316.19
    methyl propionate 202.63
    isopentyl acetate 557.96
    trichloroethylene 742.06
    n-nonanol 210.12
    cyclohexanol 278.14
    benzyl alcohol 203.65
    2-ethylhexanol 340.1
    isooctanol 183.9
    dipropyl ether 561.11
    1,2-dichlorobenzene 379.07
    ethyl lactate 83.96
    propylene carbonate 298.28
    n-methylformamide 56.65
    2-pentanol 165.27
    n-pentane 148.36
    1-propoxy-2-propanol 303.55
    1-methoxy-2-propyl acetate 405.89
    2-(2-methoxypropoxy) propanol 264.84
    mesitylene 289.81
    ε-caprolactone 459.69
    p-cymene 329.8
    epichlorohydrin 501.8
    1,1,1-trichloroethane 583.19
    2-aminoethanol 26.2
    morpholine-4-carbaldehyde 310.21
    sulfolane 378.55
    2,2,4-trimethylpentane 83.62
    2-methyltetrahydrofuran 844.76
    n-hexyl acetate 424.31
    isooctane 83.99
    2-(2-butoxyethoxy)ethanol 309.02
    sec-butyl acetate 227.21
    tert-butyl acetate 331.09
    decalin 161.07
    glycerin 30.18
    diglyme 529.61
    acrylic acid 55.26
    isopropyl myristate 246.5
    n-butyric acid 184.27
    acetyl acetate 223.74
    di(2-ethylhexyl) phthalate 188.78
    ethyl propionate 220.44
    nitromethane 110.56
    1,2-diethoxyethane 518.3
    benzonitrile 328.97
    trioctyl phosphate 142.11
    1-bromopropane 515.18
    gamma-valerolactone 498.83
    n-decanol 166.91
    triethyl phosphate 175.19
    4-methyl-2-pentanol 141.86
    propionitrile 205.88
    vinylene carbonate 246.74
    1,1,2-trichlorotrifluoroethane 188.76
    DMS 240.51
    cumene 235.6
    2-octanol 165.06
    2-hexanone 289.61
    octyl acetate 265.43
    limonene 418.46
    1,2-dimethoxyethane 364.43
    ethyl orthosilicate 191.8
    tributyl phosphate 163.9
    diacetone alcohol 224.47
    N,N-dimethylaniline 265.53
    acrylonitrile 160.55
    aniline 311.9
    1,3-propanediol 60.44
    bromobenzene 633.35
    dibromomethane 661.13
    1,1,2,2-tetrachloroethane 580.75
    2-methyl-cyclohexyl acetate 361.57
    tetrabutyl urea 208.04
    diisobutyl methanol 223.85
    2-phenylethanol 318.79
    styrene 373.33
    dioctyl adipate 279.25
    dimethyl sulfate 104.67
    ethyl butyrate 414.25
    methyl lactate 65.72
    butyl lactate 168.38
    diethyl carbonate 242.68
    propanediol butyl ether 156.77
    triethyl orthoformate 293.99
    p-tert-butyltoluene 315.33
    methyl 4-tert-butylbenzoate 297.37
    morpholine 589.85
    tert-butylamine 195.93
    n-dodecanol 140.41
    dimethoxymethane 218.66
    ethylene carbonate 223.35
    cyrene 203.24
    2-ethoxyethyl acetate 353.31
    2-ethylhexyl acetate 517.99
    1,2,4-trichlorobenzene 436.32
    4-methylpyridine 624.71
    dibutyl ether 419.3
    2,6-dimethyl-4-heptanol 223.85
    DEF 258.33
    dimethyl isosorbide 495.22
    tetrachloroethylene 341.73
    eugenol 224.67
    triacetin 291.61
    span 80 255.25
    1,4-butanediol 32.89
    1,1-dichloroethane 481.76
    2-methyl-1-pentanol 177.86
    methyl formate 52.24
    2-methyl-1-butanol 187.2
    n-decane 118.07
    butyronitrile 279.68
    3,7-dimethyl-1-octanol 238.5
    1-chlorooctane 271.38
    1-chlorotetradecane 130.24
    n-nonane 123.83
    undecane 89.16
    tert-butylcyclohexane 137.33
    cyclooctane 172.41
    cyclopentanol 237.79
    tetrahydropyran 943.8
    tert-amyl methyl ether 291.27
    2,5,8-trioxanonane 404.4
    1-hexene 330.79
    2-isopropoxyethanol 134.44
    2,2,2-trifluoroethanol 23.48
    methyl butyrate 257.81

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction