Glyphosate

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  • Identifiers

    CAS number
    1071-83-6

    Molecular formula
    C3H8NO5P

    SMILES
    C(C(=O)O)NCP(=O)(O)O

    Safety labels

    Corrosive
    Corrosive

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 76.13%
    Sweet 21.36%
    Savory 20.56%
    Clean 17.43%
    Sour 17.24%
    Cooked 14.62%
    Meaty 13.95%
    Sharp 13.95%
    Alcoholic 13.58%
    Fishy 13.44%

     

    Flavor
    Odorless 76.48%
    Mild 33.37%
    Sour 32.85%
    Very mild 27.88%
    Bland 27.44%
    Yeast 23.78%
    Faint 22.66%
    Acidic 21.33%
    Sweet-like 21.05%
    Formyl 20.14%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -4.6

    pKa est.
    5.18 (weak acid)

    Molecular weight
    169.07 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    486°C

    Melting point expt.

    • 446 °F (decomposes) (NTP, 1992)
    • 189.5 °C
    • 230 °C (dec)
    • Gilfonos, Roundup: Clear, viscous amber-colored solution; pH 4.4-4.9. Practically odorless to slight amine-like odor. Lider: Colorless crystals. MW: 169.09; MP: 200 °C

    Flash point

    • 245.38 ˚C est.

    Solubility expt.

    • 5 to 10 mg/mL at 64 °F (NTP, 1992)
    • 12000 mg/L (at 25 °C)
    • Solubility in water (20 °C): 1050 g/L /Glyphosate trimethylammonium salt/
    • In water, 10.5 g/L in water at pH 1.9 and 20 °C
    • Practically insoluble in common organic solvents, e.g. acetone, ethanol and xylene
    • Solubility in water, g/100ml at 25 °C: 1.2

  • Synonyms

    • glyphosate
    • 1071-83-6
    • N-(Phosphonomethyl)glycine
    • N-Phosphonomethyl-glycine
    • Roundup
    • Glyphosphate
    • N-Phosphonomethylglycine
    • Glycine, N-(phosphonomethyl)-
    • N-Phosphomethylglycine
    • Glyfos
    • 2-(phosphonomethylamino)acetic acid
    • Pondmaster
    • MON 2139
    • 994-61-6
    • NSC151063
    • 2-((Phosphonomethyl)amino)acetic acid
    • 2-[(phosphonomethyl)amino]acetic acid
    • Glialka
    • NSC-151063
    • CP 67573
    • CHEBI:27744
    • 4632WW1X5A
    • Mon 6000
    • Phosphonomethyliminoacetic acid
    • CHEMBL95764
    • DTXSID1024122
    • [(phosphonomethyl)amino]acetic acid
    • Tumbleweed
    • Glifonox
    • Glyphosate 100 microg/mL in Water
    • Spasor
    • Sonic
    • Sting
    • gliphosate
    • Silglif
    • MON 0573
    • GLYPHOSATE (IARC)
    • GLYPHOSATE [IARC]
    • Roundup (TN)
    • Roundup Max
    • GLYPHOSATE (MART.)
    • GLYPHOSATE [MART.]
    • (Carboxymethylamino)methylphosphonic acid
    • N-(Phosphonomethyl) Glycine
    • Caswell No. 661A
    • Buccaneer
    • Folusen
    • Glifoglex
    • Herbatop
    • HM 2028; Herbatop; Hockey; Kickdown; Klinik;NSC 151063
    • Kickdown
    • Phorsat
    • Atila
    • Forsat
    • Hockey
    • Klinik
    • Leone
    • Safal
    • ((phosphonomethyl)amino)acetic acid
    • Gliz
    • GlyGran
    • Buccaneer Plus
    • Rebel Garden
    • Glyphodin A
    • Glyphosate CT
    • Ground Bio
    • MON 39
    • Glyphosate [ISO]
    • Lancer (herbicide)
    • Glialka 36
    • Glifosan 747
    • Glyphosate [ANSI:BSI:ISO]
    • phosphonomethylglycine
    • C-K Yuyos FAV
    • CCRIS 1587
    • HSDB 3432
    • Gliz 480CS
    • CP 70139
    • EINECS 213-997-4
    • EPA Pesticide Chemical Code 417300
    • NSC 151063
    • BRN 2045054
    • glyphosat
    • Glifinox
    • Gliialka
    • UNII-4632WW1X5A
    • N-PHOSPHONOMETHYL GLYCINE
    • 2gga
    • 2ggd
    • Glyphosate 10 microg/mL in Water
    • BioTox Pest Detox
    • N-(PHOSPHONOMETHYL)-GLYCINE
    • GPF
    • GPJ
    • MON 3539
    • MFCD00055350
    • Carboxymethylaminomethanephosphinic acid
    • phosphonomethyl glycine
    • Glyphosate [M+H+]
    • HM 2028
    • Glyphosate (Standard)
    • Spectrum_001867
    • GLYPHOSATE [MI]
    • SpecPlus_000478
    • 81591-81-3
    • Spectrum2_001847
    • Spectrum3_000839
    • Spectrum4_000679
    • Spectrum5_001992
    • GLYPHOSATE [HSDB]
    • WLN: QV1M1PQQO
    • NCIStruc1_000002
    • NCIStruc2_000104
    • SCHEMBL16440
    • BSPBio_002397
    • KBioGR_001117
    • KBioSS_002384
    • SPECTRUM330047
    • 840 - Pesticides in pulses
    • DivK1c_006574
    • SPBio_001634
    • 841 - Pesticides in cereals
    • Glyphosate, isopropylamine salt
    • DTXCID004122
    • HY-B0863R
    • KBio1_001518
    • KBio2_002380
    • KBio2_004948

  • Applications

    Glyphosate (CAS 1071-83-6) is a broad-spectrum herbicide widely used in agriculture to control weeds around crops and reduce competition for nutrients, contributing to improved crop performance. It is also applied for vegetation management in non-agricultural areas, such as roadside and utility corridor weed control, to maintain facilities and rights-of-way. In forestry, glyphosate is used for site preparation and to suppress competing vegetation prior to planting. In landscaping and turf management, it is used to manage weeds on golf courses, parks, and ornamental grounds. It is also available in consumer products for home garden weed control and landscaping around residential properties.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.49
    methanol 0.68
    isopropanol 0.44
    water 9.37
    ethyl acetate 0.24
    n-propanol 0.41
    acetone 0.69
    n-butanol 0.42
    acetonitrile 0.25
    DMF 12.42
    toluene 0.2
    isobutanol 0.32
    1,4-dioxane 1.12
    methyl acetate 0.17
    THF 1.63
    2-butanone 0.33
    n-pentanol 0.32
    sec-butanol 0.34
    n-hexane 0.1
    ethylene glycol 5.07
    NMP 30.71
    cyclohexane 0.21
    DMSO 18.22
    n-butyl acetate 0.5
    n-octanol 0.5
    chloroform 0.01
    n-propyl acetate 0.22
    acetic acid 2.27
    dichloromethane 0.04
    cyclohexanone 1.32
    propylene glycol 3.7
    isopropyl acetate 0.27
    DMAc 10.06
    2-ethoxyethanol 2.67
    isopentanol 0.4
    n-heptane 0.4
    ethyl formate 0.35
    1,2-dichloroethane 0.09
    n-hexanol 0.87
    2-methoxyethanol 6.11
    isobutyl acetate 0.12
    tetrachloromethane 0.01
    n-pentyl acetate 0.38
    transcutol 6.3
    n-heptanol 0.85
    ethylbenzene 0.12
    MIBK 0.4
    2-propoxyethanol 5.14
    tert-butanol 0.64
    MTBE 0.2
    2-butoxyethanol 3.66
    propionic acid 0.9
    o-xylene 0.36
    formic acid 8.24
    diethyl ether 0.21
    m-xylene 0.3
    p-xylene 0.15
    chlorobenzene 0.05
    dimethyl carbonate 0.68
    n-octane 0.13
    formamide 8.84
    cyclopentanone 1.88
    2-pentanone 0.48
    anisole 0.23
    cyclopentyl methyl ether 1.16
    gamma-butyrolactone 2.47
    1-methoxy-2-propanol 5.33
    pyridine 0.6
    3-pentanone 0.41
    furfural 3.89
    n-dodecane 0.07
    diethylene glycol 10.95
    diisopropyl ether 0.19
    tert-amyl alcohol 0.49
    acetylacetone 1.03
    n-hexadecane 0.07
    acetophenone 0.52
    methyl propionate 0.48
    isopentyl acetate 0.38
    trichloroethylene 0.06
    n-nonanol 0.51
    cyclohexanol 0.85
    benzyl alcohol 0.48
    2-ethylhexanol 0.54
    isooctanol 0.52
    dipropyl ether 0.8
    1,2-dichlorobenzene 0.07
    ethyl lactate 0.98
    propylene carbonate 0.92
    n-methylformamide 3.23
    2-pentanol 0.36
    n-pentane 0.11
    1-propoxy-2-propanol 3.81
    1-methoxy-2-propyl acetate 1.46
    2-(2-methoxypropoxy) propanol 3.15
    mesitylene 0.31
    ε-caprolactone 1.39
    p-cymene 0.34
    epichlorohydrin 0.72
    1,1,1-trichloroethane 0.02
    2-aminoethanol 4.35
    morpholine-4-carbaldehyde 16.57
    sulfolane 12.94
    2,2,4-trimethylpentane 0.06
    2-methyltetrahydrofuran 0.68
    n-hexyl acetate 0.43
    isooctane 0.04
    2-(2-butoxyethoxy)ethanol 4.8
    sec-butyl acetate 0.15
    tert-butyl acetate 0.39
    decalin 0.09
    glycerin 21.69
    diglyme 5.87
    acrylic acid 1.67
    isopropyl myristate 0.24
    n-butyric acid 0.89
    acetyl acetate 0.2
    di(2-ethylhexyl) phthalate 0.45
    ethyl propionate 0.28
    nitromethane 2.11
    1,2-diethoxyethane 0.61
    benzonitrile 0.24
    trioctyl phosphate 0.45
    1-bromopropane 0.05
    gamma-valerolactone 6.02
    n-decanol 0.41
    triethyl phosphate 0.47
    4-methyl-2-pentanol 0.28
    propionitrile 0.16
    vinylene carbonate 0.72
    1,1,2-trichlorotrifluoroethane 2.6
    DMS 0.44
    cumene 0.14
    2-octanol 0.4
    2-hexanone 0.27
    octyl acetate 0.34
    limonene 0.49
    1,2-dimethoxyethane 1.93
    ethyl orthosilicate 0.47
    tributyl phosphate 0.35
    diacetone alcohol 1.83
    N,N-dimethylaniline 0.67
    acrylonitrile 0.32
    aniline 0.49
    1,3-propanediol 2.71
    bromobenzene 0.03
    dibromomethane 0.03
    1,1,2,2-tetrachloroethane 0.1
    2-methyl-cyclohexyl acetate 0.48
    tetrabutyl urea 1.1
    diisobutyl methanol 0.46
    2-phenylethanol 0.73
    styrene 0.1
    dioctyl adipate 0.39
    dimethyl sulfate 2.58
    ethyl butyrate 0.52
    methyl lactate 3.05
    butyl lactate 1.33
    diethyl carbonate 0.27
    propanediol butyl ether 4.69
    triethyl orthoformate 0.65
    p-tert-butyltoluene 0.35
    methyl 4-tert-butylbenzoate 1.75
    morpholine 1.8
    tert-butylamine 0.35
    n-dodecanol 0.33
    dimethoxymethane 2.63
    ethylene carbonate 0.56
    cyrene 6.14
    2-ethoxyethyl acetate 0.61
    2-ethylhexyl acetate 0.33
    1,2,4-trichlorobenzene 0.09
    4-methylpyridine 0.53
    dibutyl ether 0.31
    2,6-dimethyl-4-heptanol 0.46
    DEF 2.09
    dimethyl isosorbide 4.93
    tetrachloroethylene 0.09
    eugenol 2.4
    triacetin 0.85
    span 80 3.38
    1,4-butanediol 1.38
    1,1-dichloroethane 0.02
    2-methyl-1-pentanol 0.25
    methyl formate 1.56
    2-methyl-1-butanol 0.37
    n-decane 0.11
    butyronitrile 0.18
    3,7-dimethyl-1-octanol 0.33
    1-chlorooctane 0.13
    1-chlorotetradecane 0.09
    n-nonane 0.11
    undecane 0.08
    tert-butylcyclohexane 0.06
    cyclooctane 0.19
    cyclopentanol 1.04
    tetrahydropyran 0.44
    tert-amyl methyl ether 0.3
    2,5,8-trioxanonane 5.6
    1-hexene 0.11
    2-isopropoxyethanol 1.4
    2,2,2-trifluoroethanol 1.41
    methyl butyrate 0.39

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction