Glutaric acid

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  • Identifiers

    CAS number
    110-94-1

    Molecular formula
    C5H8O4

    SMILES
    C(CC(=O)O)CC(=O)O

    Safety labels

    Corrosive
    Corrosive

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sour 63.15%
    Odorless 59.1%
    Cheesy 34.08%
    Sharp 29.63%
    Buttery 21.27%
    Milky 21.05%
    Sweaty 21.03%
    Pungent 20.38%
    Dairy 20.34%
    Creamy 19.44%

     

    Flavor
    Odorless 73.52%
    Sour 55.27%
    Acidic 38.46%
    Rancid 31.46%
    Vinegar 29.89%
    Sweat 27.99%
    Very mild 26.47%
    Cheese 25.3%
    Mild 25.29%
    Sharp 24.99%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.3

    pKa est.
    6.28 (neutral)

    Molecular weight
    132.11 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 207.5 °F (NTP, 1992)
    • 97.8 °C
    • 97.5-98 °C
    • 95.8 °C
    • 98 °C

    Boiling point

    • 576 to 579 °F at 760 mmHg (decomposes) (NTP, 1992)
    • 303 °C
    • 200 °C @ 20 MM HG
    • 303.00 °C. @ 760.00 mm Hg

    Flash point

    • 169.94 ˚C est.

    Solubility expt.

    • greater than or equal to 100 mg/mL at 70 °F (NTP, 1992)
    • 1600000 mg/L (at 28 °C)
    • SOLUBILITY IN WATER (G/L): @ 0 DEG: 429; @ 20 DEG: 639; @ 50 DEG: 957; @ 65 DEG: 1118; FREELY SOL IN ABSOLUTE ALCOHOL, ETHER; SOL IN BENZENE, CHLOROFORM; SLIGHTLY SOL IN PETROLEUM ETHER
    • SOL IN CONCENTRATED SULFURIC ACID
    • 1600.0 mg/mL
    • Solubility in water, g/100ml at 20 °C: 63.9

  • Synonyms

    • GLUTARIC ACID
    • Pentanedioic acid
    • 110-94-1
    • 1,5-Pentanedioic acid
    • glutarate
    • 1,3-Propanedicarboxylic acid
    • Pentandioic acid
    • n-Pyrotartaric acid
    • propane-1,3-dicarboxylic acid
    • Glutarsaeure
    • CHEBI:17859
    • HSDB 5542
    • NSC 9238
    • EINECS 203-817-2
    • MFCD00004410
    • UNII-H849F7N00B
    • BRN 1209725
    • DTXSID2021654
    • AI3-24247
    • H849F7N00B
    • NSC-9238
    • Abacavir related
    • DTXCID401654
    • NSC9238
    • 4-02-00-01934 (Beilstein Handbook Reference)
    • 1,3-PENTANEDIOIC ACID (RIFM)
    • CAS-110-94-1
    • ADIPIC ACID IMPURITY A (EP IMPURITY)
    • ADIPIC ACID IMPURITY A [EP IMPURITY]
    • Pentandioate
    • 1czc
    • 1,5-Pentanedioate
    • Glutaric acid, 99%
    • 4lh3
    • 1,3-Propanedicarboxylate
    • Glutaric acid (Standard)
    • WLN: QV3VQ
    • bmse000406
    • GLUTARIC ACID [MI]
    • SCHEMBL7414
    • GLUTARIC ACID [HSDB]
    • Pentanedioic acid Glutaric acid
    • CHEMBL1162495
    • HY-W008820R
    • Tox21_202448
    • Tox21_302871
    • BDBM50485550
    • s3152
    • AKOS000118800
    • CS-W009536
    • DB03553
    • FG02567
    • HY-W008820
    • NCGC00249226-01
    • NCGC00256456-01
    • NCGC00259997-01
    • AS-13132
    • BP-21143
    • SY029948
    • G0069
    • G0245
    • NS00003673
    • EN300-17991
    • C00489
    • D70283
    • Q409622
    • Glutaric Acid (ca. 50% in Water, ca. 4.3mol/L)
    • Z57127454
    • 78FA13BF-E0C0-4EFC-948C-534CF45044E3
    • F2191-0242
    • Glutaric acid, certified reference material, TraceCERT(R)
    • InChI=1/C5H8O4/c6-4(7)2-1-3-5(8)9/h1-3H2,(H,6,7)(H,8,9
    • 203-817-2

  • Applications

    Glutaric acid (CAS 110-94-1) is a versatile diacid primarily used as a chemical intermediate in polymer synthesis. It serves as a monomer or chain extender for polyesters (including thermoplastics and unsaturated types), polyamides, and polyurethanes, enabling tuning of mechanical and thermal properties. It is also converted to glutarate esters and other derivatives that function as plasticizers, crosslinkers, or reactive intermediates in coatings, inks, and adhesive formulations. In coatings and adhesive systems, glutaric acid–based intermediates can act as curing agents or crosslinking components to improve film hardness and chemical resistance. It also serves as a building block for pharmaceutical and agrochemical intermediates and can be leveraged in the development of biobased or renewable polymer formulations, subject to formulation constraints and regulation.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 486.84
    methanol 901.28
    isopropanol 312.88
    water 1115.64
    ethyl acetate 205.79
    n-propanol 306.35
    acetone 589.52
    n-butanol 200.65
    acetonitrile 169.95
    DMF 2272.26
    toluene 15.76
    isobutanol 166.99
    1,4-dioxane 722.92
    methyl acetate 211.1
    THF 728.27
    2-butanone 220.0
    n-pentanol 109.69
    sec-butanol 160.51
    n-hexane 7.63
    ethylene glycol 459.59
    NMP 1897.62
    cyclohexane 7.93
    DMSO 1567.76
    n-butyl acetate 68.32
    n-octanol 128.26
    chloroform 19.7
    n-propyl acetate 82.28
    acetic acid 652.94
    dichloromethane 53.79
    cyclohexanone 273.37
    propylene glycol 372.2
    isopropyl acetate 107.58
    DMAc 1408.3
    2-ethoxyethanol 402.84
    isopentanol 115.12
    n-heptane 8.11
    ethyl formate 233.57
    1,2-dichloroethane 75.2
    n-hexanol 74.32
    2-methoxyethanol 887.94
    isobutyl acetate 30.74
    tetrachloromethane 3.45
    n-pentyl acetate 97.11
    transcutol 766.38
    n-heptanol 78.86
    ethylbenzene 9.83
    MIBK 75.39
    2-propoxyethanol 305.19
    tert-butanol 256.07
    MTBE 94.42
    2-butoxyethanol 230.17
    propionic acid 539.12
    o-xylene 21.5
    formic acid 908.53
    diethyl ether 141.93
    m-xylene 17.46
    p-xylene 13.57
    chlorobenzene 19.11
    dimethyl carbonate 220.66
    n-octane 5.84
    formamide 1223.87
    cyclopentanone 496.73
    2-pentanone 188.52
    anisole 55.86
    cyclopentyl methyl ether 195.42
    gamma-butyrolactone 965.29
    1-methoxy-2-propanol 622.42
    pyridine 183.51
    3-pentanone 139.48
    furfural 593.26
    n-dodecane 5.63
    diethylene glycol 336.95
    diisopropyl ether 33.18
    tert-amyl alcohol 144.01
    acetylacetone 245.52
    n-hexadecane 6.0
    acetophenone 78.91
    methyl propionate 303.85
    isopentyl acetate 45.43
    trichloroethylene 68.66
    n-nonanol 112.39
    cyclohexanol 139.2
    benzyl alcohol 82.63
    2-ethylhexanol 34.81
    isooctanol 50.98
    dipropyl ether 69.83
    1,2-dichlorobenzene 20.69
    ethyl lactate 107.88
    propylene carbonate 299.69
    n-methylformamide 1147.73
    2-pentanol 108.6
    n-pentane 9.7
    1-propoxy-2-propanol 193.13
    1-methoxy-2-propyl acetate 136.06
    2-(2-methoxypropoxy) propanol 212.08
    mesitylene 13.35
    ε-caprolactone 352.67
    p-cymene 10.61
    epichlorohydrin 489.19
    1,1,1-trichloroethane 15.43
    2-aminoethanol 557.7
    morpholine-4-carbaldehyde 1426.94
    sulfolane 1071.31
    2,2,4-trimethylpentane 3.74
    2-methyltetrahydrofuran 289.54
    n-hexyl acetate 152.57
    isooctane 2.68
    2-(2-butoxyethoxy)ethanol 360.08
    sec-butyl acetate 40.37
    tert-butyl acetate 87.01
    decalin 4.23
    glycerin 607.91
    diglyme 485.39
    acrylic acid 603.89
    isopropyl myristate 52.14
    n-butyric acid 326.73
    acetyl acetate 95.08
    di(2-ethylhexyl) phthalate 63.41
    ethyl propionate 105.87
    nitromethane 984.34
    1,2-diethoxyethane 146.35
    benzonitrile 55.55
    trioctyl phosphate 61.11
    1-bromopropane 26.42
    gamma-valerolactone 986.93
    n-decanol 82.1
    triethyl phosphate 36.24
    4-methyl-2-pentanol 44.73
    propionitrile 111.53
    vinylene carbonate 273.23
    1,1,2-trichlorotrifluoroethane 332.77
    DMS 151.0
    cumene 9.48
    2-octanol 59.13
    2-hexanone 70.04
    octyl acetate 90.15
    limonene 17.89
    1,2-dimethoxyethane 420.0
    ethyl orthosilicate 32.1
    tributyl phosphate 61.97
    diacetone alcohol 186.34
    N,N-dimethylaniline 54.85
    acrylonitrile 187.89
    aniline 78.82
    1,3-propanediol 485.87
    bromobenzene 10.42
    dibromomethane 25.91
    1,1,2,2-tetrachloroethane 61.14
    2-methyl-cyclohexyl acetate 42.31
    tetrabutyl urea 110.25
    diisobutyl methanol 22.07
    2-phenylethanol 55.78
    styrene 11.19
    dioctyl adipate 94.57
    dimethyl sulfate 398.91
    ethyl butyrate 63.3
    methyl lactate 333.28
    butyl lactate 130.73
    diethyl carbonate 39.53
    propanediol butyl ether 308.2
    triethyl orthoformate 50.61
    p-tert-butyltoluene 11.37
    methyl 4-tert-butylbenzoate 142.03
    morpholine 790.23
    tert-butylamine 96.79
    n-dodecanol 59.27
    dimethoxymethane 802.21
    ethylene carbonate 230.05
    cyrene 229.35
    2-ethoxyethyl acetate 160.67
    2-ethylhexyl acetate 33.64
    1,2,4-trichlorobenzene 28.78
    4-methylpyridine 145.44
    dibutyl ether 69.36
    2,6-dimethyl-4-heptanol 22.07
    DEF 440.72
    dimethyl isosorbide 262.96
    tetrachloroethylene 39.22
    eugenol 140.4
    triacetin 178.17
    span 80 234.22
    1,4-butanediol 197.46
    1,1-dichloroethane 31.44
    2-methyl-1-pentanol 60.61
    methyl formate 782.3
    2-methyl-1-butanol 112.48
    n-decane 9.16
    butyronitrile 96.85
    3,7-dimethyl-1-octanol 62.63
    1-chlorooctane 28.13
    1-chlorotetradecane 12.99
    n-nonane 8.73
    undecane 6.99
    tert-butylcyclohexane 3.63
    cyclooctane 4.32
    cyclopentanol 240.96
    tetrahydropyran 253.14
    tert-amyl methyl ether 80.03
    2,5,8-trioxanonane 367.74
    1-hexene 18.33
    2-isopropoxyethanol 187.83
    2,2,2-trifluoroethanol 368.19
    methyl butyrate 127.67

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction