Ganodosterone

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  • Identifiers

    CAS number
    19698-66-9

    Molecular formula
    C28H40O2

    SMILES
    C[C@H](/C=C/[C@H](C)C(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3C2=CC(=O)C4=CC(=O)CC[C@]34C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 83.2%
    Amber 43.47%
    Cedar 40.91%
    Dry 39.31%
    Sandalwood 35.54%
    Spicy 32.96%
    Vetiver 32.79%
    Orris 28.43%
    Balsamic 27.77%
    Musk 26.83%

     

    Flavor
    Herbal 41.59%
    Woody 39.04%
    Bitter 33.83%
    Spice 28.9%
    Wood 26.26%
    Herb 25.04%
    Cedarleaf 21.21%
    Terpentine 20.35%
    Lovage 20.11%
    Outdoor 19.53%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    6.5

    pKa est.
    6.69 (neutral)

    Molecular weight
    408.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    498°C

    Flash point

    • 227.76 ˚C est.

  • Synonyms

    • GANODOSTERONE
    • DTXSID501317637
    • 19698-66-9
    • RefChem:1085728
    • DTXCID301747442
    • ganodesterone
    • (22E)-Ergosta-4,7,22-triene-3,6-dione
    • SCHEMBL6378477
    • CHEMBL1801891
    • CHEBI:68082
    • (22e,24r)-ergosta-4,7,22-trien-3,6-dione
    • Q27136574
    • (9S,10R,13R,14R,17R)-17-[(E,2R,5R)-5,6-dimethylhept-3-en-2-yl]-10,13-dimethyl-2,9,11,12,14,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,6-dione
    • 19698-66-9

  • Applications

    Ganodosterone (CAS 19698-66-9) is primarily encountered in research contexts where it serves as a natural-product–derived steroidal scaffold and a potential starting point for steroid diversification. In pharmaceutical-related medicinal chemistry, it is used for lead discovery and structure–activity exploration around steroid frameworks. It is commonly employed as a research reagent and analytical reference material in natural product chemistry and metabolite profiling of Ganoderma species. It can function as a chemical synthesis intermediate for related steroid compounds, enabling the preparation of derivatives in laboratory settings. Use is typically restricted to academic and industrial research, and subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 11.43
    methanol 3.82
    isopropanol 12.63
    water 0.02
    ethyl acetate 26.1
    n-propanol 19.6
    acetone 17.77
    n-butanol 24.51
    acetonitrile 4.32
    DMF 26.57
    toluene 73.62
    isobutanol 16.04
    1,4-dioxane 47.96
    methyl acetate 16.05
    THF 67.63
    2-butanone 29.92
    n-pentanol 17.6
    sec-butanol 10.32
    n-hexane 1.71
    ethylene glycol 0.53
    NMP 43.03
    cyclohexane 3.86
    DMSO 7.3
    n-butyl acetate 28.57
    n-octanol 6.96
    chloroform 94.7
    n-propyl acetate 19.95
    acetic acid 8.63
    dichloromethane 50.26
    cyclohexanone 56.51
    propylene glycol 1.68
    isopropyl acetate 29.1
    DMAc 57.77
    2-ethoxyethanol 19.72
    isopentanol 22.53
    n-heptane 1.29
    ethyl formate 6.6
    1,2-dichloroethane 31.21
    n-hexanol 24.1
    2-methoxyethanol 20.33
    isobutyl acetate 23.27
    tetrachloromethane 11.72
    n-pentyl acetate 27.38
    transcutol 85.61
    n-heptanol 13.37
    ethylbenzene 24.71
    MIBK 28.62
    2-propoxyethanol 59.76
    tert-butanol 11.12
    MTBE 15.85
    2-butoxyethanol 35.66
    propionic acid 8.6
    o-xylene 29.4
    formic acid 1.8
    diethyl ether 26.77
    m-xylene 38.32
    p-xylene 27.79
    chlorobenzene 42.8
    dimethyl carbonate 12.39
    n-octane 0.48
    formamide 3.05
    cyclopentanone 50.56
    2-pentanone 33.35
    anisole 38.78
    cyclopentyl methyl ether 40.18
    gamma-butyrolactone 37.22
    1-methoxy-2-propanol 28.58
    pyridine 56.95
    3-pentanone 31.14
    furfural 31.1
    n-dodecane 0.35
    diethylene glycol 16.6
    diisopropyl ether 9.76
    tert-amyl alcohol 8.6
    acetylacetone 34.01
    n-hexadecane 0.44
    acetophenone 35.6
    methyl propionate 24.82
    isopentyl acetate 36.89
    trichloroethylene 77.9
    n-nonanol 8.94
    cyclohexanol 19.94
    benzyl alcohol 27.86
    2-ethylhexanol 14.12
    isooctanol 12.3
    dipropyl ether 18.11
    1,2-dichlorobenzene 38.9
    ethyl lactate 11.72
    propylene carbonate 21.96
    n-methylformamide 6.63
    2-pentanol 14.71
    n-pentane 2.03
    1-propoxy-2-propanol 42.85
    1-methoxy-2-propyl acetate 55.12
    2-(2-methoxypropoxy) propanol 30.55
    mesitylene 18.29
    ε-caprolactone 48.5
    p-cymene 12.99
    epichlorohydrin 49.45
    1,1,1-trichloroethane 35.2
    2-aminoethanol 2.99
    morpholine-4-carbaldehyde 55.48
    sulfolane 34.63
    2,2,4-trimethylpentane 1.25
    2-methyltetrahydrofuran 37.61
    n-hexyl acetate 25.58
    isooctane 1.21
    2-(2-butoxyethoxy)ethanol 38.88
    sec-butyl acetate 21.79
    tert-butyl acetate 29.97
    decalin 2.65
    glycerin 3.15
    diglyme 65.35
    acrylic acid 6.29
    isopropyl myristate 11.81
    n-butyric acid 22.87
    acetyl acetate 21.07
    di(2-ethylhexyl) phthalate 17.02
    ethyl propionate 20.87
    nitromethane 11.7
    1,2-diethoxyethane 30.84
    benzonitrile 22.9
    trioctyl phosphate 9.94
    1-bromopropane 26.12
    gamma-valerolactone 78.85
    n-decanol 5.82
    triethyl phosphate 15.9
    4-methyl-2-pentanol 13.02
    propionitrile 12.41
    vinylene carbonate 22.69
    1,1,2-trichlorotrifluoroethane 28.13
    DMS 25.18
    cumene 14.84
    2-octanol 6.7
    2-hexanone 25.18
    octyl acetate 13.44
    limonene 12.96
    1,2-dimethoxyethane 36.49
    ethyl orthosilicate 17.51
    tributyl phosphate 10.92
    diacetone alcohol 27.86
    N,N-dimethylaniline 28.46
    acrylonitrile 10.8
    aniline 40.62
    1,3-propanediol 9.76
    bromobenzene 49.64
    dibromomethane 37.74
    1,1,2,2-tetrachloroethane 61.02
    2-methyl-cyclohexyl acetate 29.38
    tetrabutyl urea 15.37
    diisobutyl methanol 9.24
    2-phenylethanol 39.38
    styrene 26.57
    dioctyl adipate 19.49
    dimethyl sulfate 16.14
    ethyl butyrate 23.26
    methyl lactate 11.25
    butyl lactate 22.09
    diethyl carbonate 15.74
    propanediol butyl ether 17.3
    triethyl orthoformate 24.17
    p-tert-butyltoluene 12.05
    methyl 4-tert-butylbenzoate 36.86
    morpholine 57.16
    tert-butylamine 7.82
    n-dodecanol 3.84
    dimethoxymethane 35.57
    ethylene carbonate 20.46
    cyrene 32.48
    2-ethoxyethyl acetate 43.44
    2-ethylhexyl acetate 30.34
    1,2,4-trichlorobenzene 49.61
    4-methylpyridine 64.87
    dibutyl ether 8.82
    2,6-dimethyl-4-heptanol 9.24
    DEF 32.23
    dimethyl isosorbide 60.04
    tetrachloroethylene 38.57
    eugenol 36.35
    triacetin 31.32
    span 80 24.06
    1,4-butanediol 3.94
    1,1-dichloroethane 31.72
    2-methyl-1-pentanol 17.92
    methyl formate 4.34
    2-methyl-1-butanol 18.64
    n-decane 0.79
    butyronitrile 15.02
    3,7-dimethyl-1-octanol 9.19
    1-chlorooctane 4.6
    1-chlorotetradecane 1.63
    n-nonane 0.6
    undecane 0.5
    tert-butylcyclohexane 2.1
    cyclooctane 1.48
    cyclopentanol 14.04
    tetrahydropyran 54.34
    tert-amyl methyl ether 13.52
    2,5,8-trioxanonane 42.95
    1-hexene 8.35
    2-isopropoxyethanol 21.42
    2,2,2-trifluoroethanol 4.18
    methyl butyrate 22.42

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction