Ganoderiol I

Overview IFRA Request a quote

  • Identifiers

    CAS number
    114567-49-6

    Molecular formula
    C31H50O5

    SMILES
    C[C@H](CCC=C(CO)CO)[C@H]1C[C@@H]([C@@]2([C@@]1(CCC3=C2[C@@H](C[C@@H]4[C@@]3(CCC(=O)C4(C)C)C)OC)C)C)O

    Safety labels

  • Odor profile

    Fragrance
    Woody 85.03%
    Amber 51.82%
    Sandalwood 51.63%
    Cedar 44.19%
    Dry 42.23%
    Balsamic 38.23%
    Vetiver 34.56%
    Musk 34.36%
    Powdery 31.05%
    Warm 29.98%

     

    Flavor
    Bitter 48.3%
    Woody 46.67%
    Herbal 31.6%
    Balsam 29.18%
    Pine 26.42%
    Sweet 26.04%
    Camphor 23.68%
    Spicy 23.53%
    Sandalwood 22.41%
    Ionone 21.36%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.0

    pKa est.
    5.68 (weak acid)

    Molecular weight
    502.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    184°C

    Flash point

    • 262.14 ˚C est.

  • Synonyms

    • Ganoderiol I
    • CHEBI:171931
    • DTXSID301183383
    • 114567-49-6
    • 15alpha,26,27-Trihydroxy-7alpha-methoxylanosta-8,24-dien-3-one
    • (7I+/-,15I+/-)-15,26,27-Trihydroxy-7-methoxylanosta-8,24-dien-3-one
    • (5R,7R,10S,13R,14R,15S,17R)-15-hydroxy-17-[(2R)-7-hydroxy-6-(hydroxymethyl)hept-5-en-2-yl]-7-methoxy-4,4,10,13,14-pentamethyl-1,2,5,6,7,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
    • 114567-49-6

  • Applications

    Chemical name: Ganoderiol I; CAS number: 114567-49-6. Ganoderiol I is a lanostane-type triterpenoid isolated from Ganoderma lucidum and is primarily used as a research chemical in natural product discovery and early pharmacological lead exploration; it also serves as an analytical reference standard for phytochemical characterization by LC-MS and NMR, supporting method development and quality control. In cosmetics and personal care, it is explored as a constituent of Ganoderma-derived extracts for formulation studies; in nutraceutical/functional foods contexts, it is evaluated as a potential component of Ganoderma-based ingredient systems. It can function as a synthetic intermediate or building block for derivatives of ganoderoid triterpenoids in industrial chemistry. Additionally, antioxidant activity studies of ganoderiol I inform formulation development in cosmetic and food-related applications, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 5.95
    methanol 9.07
    isopropanol 2.59
    water 0.03
    ethyl acetate 1.93
    n-propanol 4.83
    acetone 5.43
    n-butanol 3.14
    acetonitrile 1.39
    DMF 22.07
    toluene 2.03
    isobutanol 2.47
    1,4-dioxane 11.63
    methyl acetate 2.29
    THF 19.6
    2-butanone 4.5
    n-pentanol 3.22
    sec-butanol 1.16
    n-hexane 0.09
    ethylene glycol 1.09
    NMP 20.89
    cyclohexane 0.11
    DMSO 14.95
    n-butyl acetate 2.09
    n-octanol 1.67
    chloroform 8.03
    n-propyl acetate 2.04
    acetic acid 6.14
    dichloromethane 5.03
    cyclohexanone 8.65
    propylene glycol 1.74
    isopropyl acetate 1.79
    DMAc 21.58
    2-ethoxyethanol 10.99
    isopentanol 2.14
    n-heptane 0.08
    ethyl formate 1.95
    1,2-dichloroethane 2.9
    n-hexanol 2.91
    2-methoxyethanol 14.73
    isobutyl acetate 1.97
    tetrachloromethane 1.3
    n-pentyl acetate 3.95
    transcutol 14.34
    n-heptanol 3.09
    ethylbenzene 1.17
    MIBK 2.68
    2-propoxyethanol 18.0
    tert-butanol 1.62
    MTBE 1.2
    2-butoxyethanol 12.57
    propionic acid 2.78
    o-xylene 1.27
    formic acid 3.48
    diethyl ether 1.75
    m-xylene 1.49
    p-xylene 1.39
    chlorobenzene 2.41
    dimethyl carbonate 2.99
    n-octane 0.04
    formamide 4.33
    cyclopentanone 13.16
    2-pentanone 3.35
    anisole 3.86
    cyclopentyl methyl ether 3.92
    gamma-butyrolactone 10.09
    1-methoxy-2-propanol 11.49
    pyridine 9.61
    3-pentanone 2.78
    furfural 9.97
    n-dodecane 0.02
    diethylene glycol 10.49
    diisopropyl ether 0.42
    tert-amyl alcohol 1.01
    acetylacetone 5.02
    n-hexadecane 0.03
    acetophenone 4.75
    methyl propionate 3.15
    isopentyl acetate 2.51
    trichloroethylene 7.66
    n-nonanol 1.97
    cyclohexanol 1.61
    benzyl alcohol 5.3
    2-ethylhexanol 1.29
    isooctanol 2.29
    dipropyl ether 1.44
    1,2-dichlorobenzene 2.41
    ethyl lactate 2.43
    propylene carbonate 3.97
    n-methylformamide 7.68
    2-pentanol 0.97
    n-pentane 0.07
    1-propoxy-2-propanol 8.93
    1-methoxy-2-propyl acetate 5.77
    2-(2-methoxypropoxy) propanol 6.93
    mesitylene 0.78
    ε-caprolactone 6.87
    p-cymene 0.78
    epichlorohydrin 12.1
    1,1,1-trichloroethane 2.06
    2-aminoethanol 3.7
    morpholine-4-carbaldehyde 24.5
    sulfolane 15.3
    2,2,4-trimethylpentane 0.05
    2-methyltetrahydrofuran 4.25
    n-hexyl acetate 3.73
    isooctane 0.05
    2-(2-butoxyethoxy)ethanol 10.31
    sec-butyl acetate 1.34
    tert-butyl acetate 2.36
    decalin 0.11
    glycerin 4.01
    diglyme 17.44
    acrylic acid 3.56
    isopropyl myristate 0.92
    n-butyric acid 3.84
    acetyl acetate 2.19
    di(2-ethylhexyl) phthalate 2.88
    ethyl propionate 1.7
    nitromethane 7.69
    1,2-diethoxyethane 3.17
    benzonitrile 3.09
    trioctyl phosphate 1.65
    1-bromopropane 1.09
    gamma-valerolactone 25.7
    n-decanol 0.94
    triethyl phosphate 1.53
    4-methyl-2-pentanol 0.94
    propionitrile 1.69
    vinylene carbonate 5.18
    1,1,2-trichlorotrifluoroethane 12.41
    DMS 3.27
    cumene 0.86
    2-octanol 1.14
    2-hexanone 3.17
    octyl acetate 1.55
    limonene 0.81
    1,2-dimethoxyethane 12.57
    ethyl orthosilicate 1.62
    tributyl phosphate 1.24
    diacetone alcohol 4.67
    N,N-dimethylaniline 3.19
    acrylonitrile 2.76
    aniline 3.23
    1,3-propanediol 6.35
    bromobenzene 2.16
    dibromomethane 2.91
    1,1,2,2-tetrachloroethane 6.0
    2-methyl-cyclohexyl acetate 2.89
    tetrabutyl urea 2.29
    diisobutyl methanol 0.69
    2-phenylethanol 5.78
    styrene 1.29
    dioctyl adipate 2.3
    dimethyl sulfate 5.66
    ethyl butyrate 1.75
    methyl lactate 3.96
    butyl lactate 4.96
    diethyl carbonate 1.2
    propanediol butyl ether 9.07
    triethyl orthoformate 2.15
    p-tert-butyltoluene 0.77
    methyl 4-tert-butylbenzoate 6.61
    morpholine 14.83
    tert-butylamine 0.6
    n-dodecanol 0.46
    dimethoxymethane 15.94
    ethylene carbonate 3.87
    cyrene 11.15
    2-ethoxyethyl acetate 7.27
    2-ethylhexyl acetate 1.93
    1,2,4-trichlorobenzene 3.54
    4-methylpyridine 6.05
    dibutyl ether 0.73
    2,6-dimethyl-4-heptanol 0.69
    DEF 4.63
    dimethyl isosorbide 11.3
    tetrachloroethylene 4.92
    eugenol 8.31
    triacetin 4.92
    span 80 6.33
    1,4-butanediol 3.19
    1,1-dichloroethane 1.86
    2-methyl-1-pentanol 2.1
    methyl formate 4.42
    2-methyl-1-butanol 1.8
    n-decane 0.07
    butyronitrile 1.59
    3,7-dimethyl-1-octanol 1.17
    1-chlorooctane 0.43
    1-chlorotetradecane 0.1
    n-nonane 0.06
    undecane 0.04
    tert-butylcyclohexane 0.1
    cyclooctane 0.06
    cyclopentanol 2.49
    tetrahydropyran 4.55
    tert-amyl methyl ether 0.91
    2,5,8-trioxanonane 10.44
    1-hexene 0.42
    2-isopropoxyethanol 6.32
    2,2,2-trifluoroethanol 2.72
    methyl butyrate 2.35

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction