Ganoderiol D

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  • Identifiers

    CAS number
    114567-45-2

    Molecular formula
    C30H48O5

    SMILES
    CC(CCC(C(C)(CO)O)O)C1CCC2(C1(CCC3=C2C(=O)CC4C3(CCC(=O)C4(C)C)C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Woody 83.53%
    Amber 53.28%
    Dry 44.93%
    Cedar 44.54%
    Sandalwood 42.39%
    Musk 41.87%
    Vetiver 33.57%
    Balsamic 32.24%
    Powdery 29.95%
    Animal 27.47%

     

    Flavor
    Bitter 54.18%
    Woody 42.43%
    Camphor 26.47%
    Pine 25.54%
    Herbal 23.96%
    Odorless 23.37%
    Balsam 22.82%
    Sandalwood 21.76%
    Cedarleaf 21.72%
    Fir 21.38%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    4.1

    pKa est.
    7.17 (neutral)

    Molecular weight
    488.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    108°C

    Flash point

    • 271.21 ˚C est.

  • Synonyms

    • Ganoderiol D
    • 4,4,10,13,14-pentamethyl-17-(5,6,7-trihydroxy-6-methylheptan-2-yl)-2,5,6,11,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,7-dione
    • 114567-45-2
    • (5R,10S,13R,14R,17R)-4,4,10,13,14-Pentamethyl-17-[(2R)-5,6,7-trihydroxy-6-methylheptan-2-yl]-2,5,6,11,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthrene-3,7-dione
    • SCHEMBL29934928
    • CHEBI:183538
    • 24,25,26-Tetrahydroxy-8-lanostene-3,7-dione
    • 114567-45-2

  • Applications

    Ganoderiol D (CAS 114567-45-2) is a natural triterpenoid compound isolated from Ganoderma lucidum. It is studied as a potential bioactive ingredient for cosmetics and personal care formulations, with interest in skin conditioning and formulation development. In pharmaceuticals, it is commonly evaluated as a natural lead compound or starting point for the synthesis of related bioactive molecules. In nutraceuticals, it is considered for inclusion in natural-source dietary supplement formulations. In analytical and research settings, it can serve as a reference standard or analytical target for method development of triterpenoids. Additionally, it may function as an intermediate in synthetic routes toward ganoderiol-type compounds and other related triterpenoids.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 22.32
    methanol 29.97
    isopropanol 11.33
    water 0.03
    ethyl acetate 3.37
    n-propanol 15.7
    acetone 11.47
    n-butanol 7.72
    acetonitrile 2.41
    DMF 75.72
    toluene 1.94
    isobutanol 5.93
    1,4-dioxane 24.88
    methyl acetate 4.1
    THF 50.59
    2-butanone 7.64
    n-pentanol 4.58
    sec-butanol 3.29
    n-hexane 0.09
    ethylene glycol 4.17
    NMP 28.95
    cyclohexane 0.1
    DMSO 36.54
    n-butyl acetate 3.16
    n-octanol 2.23
    chloroform 12.19
    n-propyl acetate 2.69
    acetic acid 15.87
    dichloromethane 6.58
    cyclohexanone 11.2
    propylene glycol 7.32
    isopropyl acetate 3.39
    DMAc 36.89
    2-ethoxyethanol 23.77
    isopentanol 3.89
    n-heptane 0.07
    ethyl formate 3.72
    1,2-dichloroethane 3.65
    n-hexanol 4.67
    2-methoxyethanol 51.89
    isobutyl acetate 2.35
    tetrachloromethane 1.49
    n-pentyl acetate 5.63
    transcutol 33.93
    n-heptanol 4.07
    ethylbenzene 1.01
    MIBK 4.01
    2-propoxyethanol 40.49
    tert-butanol 5.27
    MTBE 2.42
    2-butoxyethanol 22.51
    propionic acid 5.77
    o-xylene 1.08
    formic acid 9.26
    diethyl ether 3.65
    m-xylene 1.3
    p-xylene 1.13
    chlorobenzene 2.47
    dimethyl carbonate 6.04
    n-octane 0.05
    formamide 11.61
    cyclopentanone 20.49
    2-pentanone 5.55
    anisole 4.58
    cyclopentyl methyl ether 6.03
    gamma-butyrolactone 18.66
    1-methoxy-2-propanol 38.3
    pyridine 13.47
    3-pentanone 3.56
    furfural 18.3
    n-dodecane 0.02
    diethylene glycol 28.11
    diisopropyl ether 0.66
    tert-amyl alcohol 2.29
    acetylacetone 9.39
    n-hexadecane 0.03
    acetophenone 4.95
    methyl propionate 5.23
    isopentyl acetate 3.59
    trichloroethylene 10.18
    n-nonanol 2.5
    cyclohexanol 2.41
    benzyl alcohol 6.79
    2-ethylhexanol 1.4
    isooctanol 2.8
    dipropyl ether 1.99
    1,2-dichlorobenzene 2.36
    ethyl lactate 3.91
    propylene carbonate 6.7
    n-methylformamide 22.04
    2-pentanol 2.18
    n-pentane 0.09
    1-propoxy-2-propanol 18.03
    1-methoxy-2-propyl acetate 10.22
    2-(2-methoxypropoxy) propanol 11.35
    mesitylene 0.64
    ε-caprolactone 9.83
    p-cymene 0.66
    epichlorohydrin 22.58
    1,1,1-trichloroethane 2.69
    2-aminoethanol 14.61
    morpholine-4-carbaldehyde 47.37
    sulfolane 24.23
    2,2,4-trimethylpentane 0.05
    2-methyltetrahydrofuran 7.46
    n-hexyl acetate 5.54
    isooctane 0.05
    2-(2-butoxyethoxy)ethanol 17.91
    sec-butyl acetate 1.73
    tert-butyl acetate 4.01
    decalin 0.08
    glycerin 14.37
    diglyme 33.58
    acrylic acid 7.07
    isopropyl myristate 1.18
    n-butyric acid 8.24
    acetyl acetate 3.68
    di(2-ethylhexyl) phthalate 3.34
    ethyl propionate 2.33
    nitromethane 19.1
    1,2-diethoxyethane 5.74
    benzonitrile 3.73
    trioctyl phosphate 1.99
    1-bromopropane 1.41
    gamma-valerolactone 49.45
    n-decanol 1.17
    triethyl phosphate 1.83
    4-methyl-2-pentanol 1.55
    propionitrile 2.88
    vinylene carbonate 8.3
    1,1,2-trichlorotrifluoroethane 23.27
    DMS 5.33
    cumene 0.67
    2-octanol 1.62
    2-hexanone 3.72
    octyl acetate 2.07
    limonene 0.73
    1,2-dimethoxyethane 25.02
    ethyl orthosilicate 1.85
    tributyl phosphate 1.6
    diacetone alcohol 8.69
    N,N-dimethylaniline 3.11
    acrylonitrile 4.89
    aniline 4.47
    1,3-propanediol 22.54
    bromobenzene 1.92
    dibromomethane 3.55
    1,1,2,2-tetrachloroethane 8.27
    2-methyl-cyclohexyl acetate 3.13
    tetrabutyl urea 2.77
    diisobutyl methanol 0.8
    2-phenylethanol 7.65
    styrene 1.18
    dioctyl adipate 2.91
    dimethyl sulfate 10.53
    ethyl butyrate 2.23
    methyl lactate 8.95
    butyl lactate 7.79
    diethyl carbonate 1.56
    propanediol butyl ether 16.69
    triethyl orthoformate 2.84
    p-tert-butyltoluene 0.67
    methyl 4-tert-butylbenzoate 8.6
    morpholine 35.54
    tert-butylamine 1.46
    n-dodecanol 0.55
    dimethoxymethane 45.37
    ethylene carbonate 6.1
    cyrene 13.51
    2-ethoxyethyl acetate 12.12
    2-ethylhexyl acetate 2.33
    1,2,4-trichlorobenzene 3.62
    4-methylpyridine 8.45
    dibutyl ether 1.08
    2,6-dimethyl-4-heptanol 0.8
    DEF 7.19
    dimethyl isosorbide 16.94
    tetrachloroethylene 6.39
    eugenol 11.36
    triacetin 7.83
    span 80 9.62
    1,4-butanediol 6.69
    1,1-dichloroethane 2.83
    2-methyl-1-pentanol 2.47
    methyl formate 11.91
    2-methyl-1-butanol 3.17
    n-decane 0.07
    butyronitrile 2.62
    3,7-dimethyl-1-octanol 1.52
    1-chlorooctane 0.51
    1-chlorotetradecane 0.1
    n-nonane 0.06
    undecane 0.04
    tert-butylcyclohexane 0.08
    cyclooctane 0.05
    cyclopentanol 4.93
    tetrahydropyran 8.7
    tert-amyl methyl ether 1.54
    2,5,8-trioxanonane 17.59
    1-hexene 0.43
    2-isopropoxyethanol 11.18
    2,2,2-trifluoroethanol 5.88
    methyl butyrate 3.16

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction