Ganoderic Acid K

Overview IFRA Request a quote

  • Identifiers

    CAS number
    104700-95-0

    Molecular formula
    C32H46O9

    SMILES
    C[C@H](CC(=O)CC(C)C(=O)O)[C@H]1CC(=O)[C@@]2([C@@]1([C@@H](C(=O)C3=C2[C@H](C[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)O)OC(=O)C)C)C

    Safety labels

  • Odor profile

    Fragrance
    Odorless 50.51%
    Woody 44.2%
    Cooling 27.99%
    Mint 26.86%
    Dry 26.13%
    Cedar 23.02%
    Amber 20.86%
    Spicy 19.97%
    Warm 18.94%
    Balsamic 17.85%

     

    Flavor
    Bitter 83.84%
    Odorless 28.59%
    Bland 25.21%
    Sweet-like 21.26%
    Cedarleaf 21.13%
    Parsley 19.69%
    Ripe apricot 19.61%
    Heather 19.46%
    Broom 19.41%
    Red fruit 19.31%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    2.2

    pKa est.
    3.63 (weak acid)

    Molecular weight
    574.7 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    353°C

    Flash point

    • 277.3 ˚C est.

  • Synonyms

    • Ganoderic Acid K
    • DTXSID601316799
    • RefChem:1085724
    • DTXCID501746626
    • (6R)-6-((3S,5R,7S,10S,12S,13R,14R,17R)-12-acetyloxy-3,7-dihydroxy-4,4,10,13,14-pentamethyl-11,15-dioxo-2,3,5,6,7,12,16,17-octahydro-1H-cyclopenta(a)phenanthren-17-yl)-2-methyl-4-oxoheptanoic acid
    • 104700-95-0
    • CHEMBL1922177
    • lucidenic acid GS-3
    • SCHEMBL16799188
    • BDBM50359043
    • 104700-95-0

  • Applications

    Ganoderic Acid K is a naturally occurring triterpenoid component from Ganoderma lucidum extracts and is commonly handled as a bioactive natural product across several practical applications, including cosmetics/personal care, pharmaceutical research, nutraceutical development, and chemical research. In cosmetics and personal care, it may be explored as a skin-beneficial bioactive ingredient with antioxidant or anti-inflammatory potential when formulated from botanical extracts. In the pharmaceutical and medicinal chemistry space, it is often studied as a natural product lead or reference compound for pharmacological activity and SAR investigations of related ganoderic triterpenoids. In nutraceuticals/functional foods, it may be present in Ganoderma-derived extracts and evaluated for potential health-supporting roles within regulatory limits. In chemical research, it serves as a reference standard or intermediate in isolation, structure elucidation, and synthesis of related triterpenoids. Subject to local regulations and formulation limits, its use is guided by applicable safety data and regulatory constraints.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 95.14
    methanol 111.22
    isopropanol 64.95
    water 0.13
    ethyl acetate 24.18
    n-propanol 74.28
    acetone 93.71
    n-butanol 42.9
    acetonitrile 21.7
    DMF 276.07
    toluene 5.83
    isobutanol 33.83
    1,4-dioxane 120.42
    methyl acetate 37.93
    THF 330.77
    2-butanone 63.71
    n-pentanol 30.01
    sec-butanol 32.8
    n-hexane 0.39
    ethylene glycol 25.05
    NMP 221.7
    cyclohexane 0.57
    DMSO 334.63
    n-butyl acetate 13.99
    n-octanol 5.88
    chloroform 55.58
    n-propyl acetate 16.41
    acetic acid 168.74
    dichloromethane 41.94
    cyclohexanone 83.43
    propylene glycol 40.19
    isopropyl acetate 14.44
    DMAc 230.93
    2-ethoxyethanol 105.63
    isopentanol 20.28
    n-heptane 0.18
    ethyl formate 30.67
    1,2-dichloroethane 28.29
    n-hexanol 16.28
    2-methoxyethanol 207.69
    isobutyl acetate 8.41
    tetrachloromethane 6.24
    n-pentyl acetate 13.33
    transcutol 63.37
    n-heptanol 9.6
    ethylbenzene 2.69
    MIBK 13.76
    2-propoxyethanol 94.71
    tert-butanol 31.32
    MTBE 11.67
    2-butoxyethanol 46.71
    propionic acid 48.98
    o-xylene 2.91
    formic acid 73.41
    diethyl ether 19.81
    m-xylene 2.47
    p-xylene 3.25
    chlorobenzene 8.59
    dimethyl carbonate 30.6
    n-octane 0.12
    formamide 84.17
    cyclopentanone 157.72
    2-pentanone 36.98
    anisole 11.73
    cyclopentyl methyl ether 30.71
    gamma-butyrolactone 162.17
    1-methoxy-2-propanol 126.56
    pyridine 67.54
    3-pentanone 23.14
    furfural 89.01
    n-dodecane 0.08
    diethylene glycol 75.81
    diisopropyl ether 2.11
    tert-amyl alcohol 20.54
    acetylacetone 41.41
    n-hexadecane 0.1
    acetophenone 15.53
    methyl propionate 33.78
    isopentyl acetate 11.04
    trichloroethylene 55.91
    n-nonanol 6.19
    cyclohexanol 18.78
    benzyl alcohol 23.89
    2-ethylhexanol 4.43
    isooctanol 5.67
    dipropyl ether 6.1
    1,2-dichlorobenzene 6.79
    ethyl lactate 14.3
    propylene carbonate 44.63
    n-methylformamide 121.46
    2-pentanol 13.59
    n-pentane 0.44
    1-propoxy-2-propanol 40.06
    1-methoxy-2-propyl acetate 24.72
    2-(2-methoxypropoxy) propanol 22.75
    mesitylene 1.1
    ε-caprolactone 69.91
    p-cymene 1.14
    epichlorohydrin 155.91
    1,1,1-trichloroethane 16.81
    2-aminoethanol 59.73
    morpholine-4-carbaldehyde 221.05
    sulfolane 205.4
    2,2,4-trimethylpentane 0.16
    2-methyltetrahydrofuran 74.85
    n-hexyl acetate 14.4
    isooctane 0.1
    2-(2-butoxyethoxy)ethanol 37.43
    sec-butyl acetate 7.99
    tert-butyl acetate 11.05
    decalin 0.27
    glycerin 67.73
    diglyme 65.62
    acrylic acid 53.74
    isopropyl myristate 3.11
    n-butyric acid 53.65
    acetyl acetate 17.76
    di(2-ethylhexyl) phthalate 7.27
    ethyl propionate 12.41
    nitromethane 156.37
    1,2-diethoxyethane 16.84
    benzonitrile 13.12
    trioctyl phosphate 4.96
    1-bromopropane 12.4
    gamma-valerolactone 265.27
    n-decanol 3.39
    triethyl phosphate 5.06
    4-methyl-2-pentanol 5.16
    propionitrile 19.55
    vinylene carbonate 44.03
    1,1,2-trichlorotrifluoroethane 105.87
    DMS 14.99
    cumene 1.47
    2-octanol 4.21
    2-hexanone 23.15
    octyl acetate 6.3
    limonene 1.69
    1,2-dimethoxyethane 104.85
    ethyl orthosilicate 4.71
    tributyl phosphate 4.68
    diacetone alcohol 29.76
    N,N-dimethylaniline 7.95
    acrylonitrile 28.94
    aniline 17.92
    1,3-propanediol 98.11
    bromobenzene 6.24
    dibromomethane 24.04
    1,1,2,2-tetrachloroethane 46.55
    2-methyl-cyclohexyl acetate 8.56
    tetrabutyl urea 8.52
    diisobutyl methanol 1.71
    2-phenylethanol 18.69
    styrene 3.39
    dioctyl adipate 7.61
    dimethyl sulfate 56.94
    ethyl butyrate 8.47
    methyl lactate 39.36
    butyl lactate 15.71
    diethyl carbonate 5.75
    propanediol butyl ether 37.33
    triethyl orthoformate 7.24
    p-tert-butyltoluene 1.03
    methyl 4-tert-butylbenzoate 14.62
    morpholine 182.77
    tert-butylamine 7.34
    n-dodecanol 1.85
    dimethoxymethane 130.73
    ethylene carbonate 36.69
    cyrene 45.52
    2-ethoxyethyl acetate 27.22
    2-ethylhexyl acetate 7.41
    1,2,4-trichlorobenzene 11.74
    4-methylpyridine 42.67
    dibutyl ether 3.45
    2,6-dimethyl-4-heptanol 1.71
    DEF 47.19
    dimethyl isosorbide 35.04
    tetrachloroethylene 27.09
    eugenol 17.75
    triacetin 15.94
    span 80 21.5
    1,4-butanediol 37.87
    1,1-dichloroethane 22.88
    2-methyl-1-pentanol 15.47
    methyl formate 82.07
    2-methyl-1-butanol 21.1
    n-decane 0.19
    butyronitrile 17.69
    3,7-dimethyl-1-octanol 3.45
    1-chlorooctane 1.48
    1-chlorotetradecane 0.41
    n-nonane 0.16
    undecane 0.12
    tert-butylcyclohexane 0.2
    cyclooctane 0.14
    cyclopentanol 49.76
    tetrahydropyran 64.71
    tert-amyl methyl ether 8.12
    2,5,8-trioxanonane 36.53
    1-hexene 2.41
    2-isopropoxyethanol 45.36
    2,2,2-trifluoroethanol 48.42
    methyl butyrate 19.43

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction