Ganoderenic acid E

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  • Identifiers

    CAS number
    110241-23-1

    Molecular formula
    C30H40O8

    SMILES
    CC(CC(=O)/C=C(\C)/C1CC(=O)C2(C1(C(C(=O)C3=C2C(CC4C3(CCC(=O)C4(C)C)C)O)O)C)C)C(=O)O

    Safety labels

  • Odor profile

    Fragrance
    Woody 50.46%
    Odorless 36.22%
    Sweet 28.46%
    Mint 27.59%
    Dry 27.56%
    Tobacco 23.92%
    Camphoreous 23.53%
    Spicy 23.16%
    Cedar 22.99%
    Cooling 22.78%

     

    Flavor
    Bitter 84.96%
    Odorless 26.16%
    Bland 22.59%
    Cedarleaf 21.04%
    Sweet-like 20.83%
    Parsley 19.64%
    Leaves 19.64%
    Ripe apricot 19.59%
    Fenugreek 19.45%
    Broom 19.27%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    1.5

    pKa est.
    3.87 (weak acid)

    Molecular weight
    528.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    314°C

    Melting point expt.

    • 227 - 229 °C

    Flash point

    • 293.73 ˚C est.

  • Synonyms

    • Ganoderenic acid E
    • 110241-23-1
    • AKOS040760406
    • (E)-6-(7,12-dihydroxy-4,4,10,13,14-pentamethyl-3,11,15-trioxo-1,2,5,6,7,12,16,17-octahydrocyclopenta[a]phenanthren-17-yl)-2-methyl-4-oxohept-5-enoic acid
    • 110241-23-1

  • Applications

    Ganoderenic acid E (CAS 110241-23-1) is a lanostane-type triterpenoid isolated from Ganoderma species. Real-world applications are mainly in research and natural product workflows, with potential use in formulation development through Ganoderma-derived extracts. In pharmaceutical/medicinal chemistry, it is explored as a lead structure for the discovery of derivatives and as a chemical probe in analytical studies. In cosmetics/personal care, Ganoderma constituents may be used as natural cosmetic ingredients in formulations. In analytical chemistry, ganoderenic acid E can serve as a reference standard or analytical target for isolation and quantification (e.g., LC-MS/NMR) of related triterpenoids. In organic synthesis, it may function as an intermediate or building block to access related triterpenoid compounds. Its use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 25.48
    methanol 43.01
    isopropanol 14.25
    water 0.08
    ethyl acetate 5.07
    n-propanol 17.82
    acetone 27.22
    n-butanol 8.55
    acetonitrile 7.22
    DMF 103.64
    toluene 1.56
    isobutanol 7.22
    1,4-dioxane 43.5
    methyl acetate 9.77
    THF 100.55
    2-butanone 15.2
    n-pentanol 5.92
    sec-butanol 5.5
    n-hexane 0.1
    ethylene glycol 9.94
    NMP 56.72
    cyclohexane 0.15
    DMSO 119.15
    n-butyl acetate 3.25
    n-octanol 1.59
    chloroform 14.91
    n-propyl acetate 3.59
    acetic acid 32.69
    dichloromethane 10.57
    cyclohexanone 20.52
    propylene glycol 10.45
    isopropyl acetate 3.05
    DMAc 64.53
    2-ethoxyethanol 29.99
    isopentanol 4.0
    n-heptane 0.05
    ethyl formate 6.63
    1,2-dichloroethane 6.9
    n-hexanol 4.04
    2-methoxyethanol 65.15
    isobutyl acetate 1.98
    tetrachloromethane 1.74
    n-pentyl acetate 3.67
    transcutol 15.23
    n-heptanol 2.9
    ethylbenzene 0.78
    MIBK 3.43
    2-propoxyethanol 30.68
    tert-butanol 7.48
    MTBE 2.48
    2-butoxyethanol 14.19
    propionic acid 10.06
    o-xylene 0.84
    formic acid 22.25
    diethyl ether 4.75
    m-xylene 0.73
    p-xylene 1.09
    chlorobenzene 2.12
    dimethyl carbonate 9.02
    n-octane 0.05
    formamide 29.29
    cyclopentanone 44.65
    2-pentanone 7.64
    anisole 3.43
    cyclopentyl methyl ether 7.3
    gamma-butyrolactone 40.15
    1-methoxy-2-propanol 31.97
    pyridine 20.64
    3-pentanone 5.45
    furfural 24.25
    n-dodecane 0.02
    diethylene glycol 29.89
    diisopropyl ether 0.51
    tert-amyl alcohol 3.81
    acetylacetone 10.52
    n-hexadecane 0.03
    acetophenone 4.32
    methyl propionate 7.98
    isopentyl acetate 2.55
    trichloroethylene 13.95
    n-nonanol 1.7
    cyclohexanol 3.58
    benzyl alcohol 6.48
    2-ethylhexanol 1.06
    isooctanol 1.71
    dipropyl ether 1.68
    1,2-dichlorobenzene 1.72
    ethyl lactate 3.97
    propylene carbonate 9.03
    n-methylformamide 42.55
    2-pentanol 2.31
    n-pentane 0.1
    1-propoxy-2-propanol 11.83
    1-methoxy-2-propyl acetate 6.67
    2-(2-methoxypropoxy) propanol 6.44
    mesitylene 0.38
    ε-caprolactone 14.53
    p-cymene 0.35
    epichlorohydrin 42.04
    1,1,1-trichloroethane 3.71
    2-aminoethanol 17.9
    morpholine-4-carbaldehyde 69.0
    sulfolane 54.71
    2,2,4-trimethylpentane 0.04
    2-methyltetrahydrofuran 16.69
    n-hexyl acetate 3.69
    isooctane 0.02
    2-(2-butoxyethoxy)ethanol 9.87
    sec-butyl acetate 1.65
    tert-butyl acetate 2.78
    decalin 0.07
    glycerin 20.28
    diglyme 19.54
    acrylic acid 12.74
    isopropyl myristate 0.82
    n-butyric acid 9.08
    acetyl acetate 3.94
    di(2-ethylhexyl) phthalate 2.18
    ethyl propionate 3.01
    nitromethane 45.9
    1,2-diethoxyethane 4.55
    benzonitrile 3.98
    trioctyl phosphate 1.37
    1-bromopropane 2.51
    gamma-valerolactone 77.77
    n-decanol 0.92
    triethyl phosphate 1.47
    4-methyl-2-pentanol 1.11
    propionitrile 5.79
    vinylene carbonate 10.61
    1,1,2-trichlorotrifluoroethane 30.91
    DMS 4.72
    cumene 0.46
    2-octanol 1.25
    2-hexanone 5.55
    octyl acetate 1.57
    limonene 0.45
    1,2-dimethoxyethane 34.48
    ethyl orthosilicate 1.35
    tributyl phosphate 1.18
    diacetone alcohol 7.35
    N,N-dimethylaniline 2.39
    acrylonitrile 9.73
    aniline 4.48
    1,3-propanediol 27.82
    bromobenzene 1.55
    dibromomethane 5.75
    1,1,2,2-tetrachloroethane 11.62
    2-methyl-cyclohexyl acetate 2.21
    tetrabutyl urea 2.4
    diisobutyl methanol 0.49
    2-phenylethanol 5.54
    styrene 0.94
    dioctyl adipate 1.99
    dimethyl sulfate 15.85
    ethyl butyrate 2.02
    methyl lactate 10.36
    butyl lactate 4.47
    diethyl carbonate 1.51
    propanediol butyl ether 9.96
    triethyl orthoformate 2.03
    p-tert-butyltoluene 0.32
    methyl 4-tert-butylbenzoate 4.54
    morpholine 54.18
    tert-butylamine 1.61
    n-dodecanol 0.49
    dimethoxymethane 48.38
    ethylene carbonate 8.56
    cyrene 13.23
    2-ethoxyethyl acetate 7.87
    2-ethylhexyl acetate 1.78
    1,2,4-trichlorobenzene 2.94
    4-methylpyridine 11.16
    dibutyl ether 0.86
    2,6-dimethyl-4-heptanol 0.49
    DEF 10.89
    dimethyl isosorbide 11.06
    tetrachloroethylene 7.87
    eugenol 5.96
    triacetin 4.61
    span 80 5.77
    1,4-butanediol 10.52
    1,1-dichloroethane 4.95
    2-methyl-1-pentanol 3.04
    methyl formate 26.39
    2-methyl-1-butanol 3.89
    n-decane 0.06
    butyronitrile 4.42
    3,7-dimethyl-1-octanol 0.88
    1-chlorooctane 0.41
    1-chlorotetradecane 0.11
    n-nonane 0.05
    undecane 0.04
    tert-butylcyclohexane 0.05
    cyclooctane 0.04
    cyclopentanol 10.04
    tetrahydropyran 15.29
    tert-amyl methyl ether 1.72
    2,5,8-trioxanonane 11.04
    1-hexene 0.55
    2-isopropoxyethanol 11.71
    2,2,2-trifluoroethanol 11.4
    methyl butyrate 4.3

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction