Fluoromethane

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  • Identifiers

    CAS number
    593-53-3

    Molecular formula
    CH3F

    SMILES
    CF

    Safety labels

    Flammable
    Flammable

    Compressed Gas
    Compressed Gas

  • Odor profile

    Fragrance
    Alcoholic 51.29%
    Ethereal 50.89%
    Solvent 42.19%
    Fermented 42.04%
    Sweet 36.15%
    Fishy 35.76%
    Gassy 34.24%
    Musty 32.59%
    Oily 31.54%
    Pungent 30.5%

     

    Flavor
    Sulfur 37.24%
    Gasoline 35.44%
    Egg 35.41%
    Garlic 34.83%
    Fishy 33.51%
    Rotten 29.0%
    Decomposing cabbage 28.17%
    Fruity 25.35%
    Sulfurous 24.46%
    Pungent 22.7%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.6

    pKa est.
    5.8 (weak acid)

    Molecular weight
    34.033 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Boiling point est.
    -76°C

    Flash point

    • -83.01 ˚C est.

  • Synonyms

    • FLUOROMETHANE
    • Methyl fluoride
    • 593-53-3
    • Methane, fluoro-
    • Freon 41
    • 51311-17-2
    • HFC-41
    • CH3F
    • Fluormethan
    • Methylfluorid
    • Monofluormethan
    • UN2454
    • 54A9X6F0CM
    • CHEBI:28826
    • EINECS 209-796-6
    • FLUOROMETHANE [MI]
    • Methyl fluoride, or Refrigerant gas R 41
    • HFC 41
    • DTXSID6060474
    • UN-2454
    • R 41
    • Fluorocarbon
    • MeF
    • UNII-54A9X6F0CM
    • Fluorographite
    • Fluoromethyl
    • carbon-fluorine
    • fluoranylmethane
    • fluoro-methane
    • methane, fluoro
    • Fluoromethylidyne
    • Fluoro methyl group
    • MFCD00039282
    • Methylidyne, fluoro-
    • Refrigerant gas R 41
    • Fluoromethane, FC-41
    • Carbon monofluoride polymer
    • CHEMBL116838
    • DTXCID4042593
    • DTXSID80958535
    • ISOSXCFSIDVNNC-UHFFFAOYSA-N
    • DTXSID101315196
    • c0354
    • AKOS005762834
    • FF79102
    • UN 2454
    • Graphite Fluoride (Carbon Monofluoride)
    • 13453-52-6
    • F 41
    • F-41
    • R-41
    • NS00080257
    • A832279
    • Graphite Fluoride (Carbon Monofluoride) Nanopowder
    • Q421738
    • Methyl fluoride, or Refrigerant gas R 41 [UN2454] [Flammable gas]
    • 209-796-6
    • 3889-75-6

  • Applications

    Methyl fluoride, also known as fluoromethane (CAS number: 593-53-3), is primarily used as a fluorinated-alkyl building block in organofluorine chemistry, serving as an intermediate for the synthesis of more complex fluorinated compounds. It is also employed as a process gas or precursor in electronics manufacturing, notably in plasma-assisted fluorination and etching/cleaning steps. In polymers and coatings chemistry, it can act as a source of fluoromethyl groups for specialized fluorinated polymers and resins. Historically it has been considered as a refrigerant or blowing agent in specialty cooling and foam formulations, though its use is constrained by regulatory considerations. It may be evaluated as a solvent or reagent under tightly controlled conditions in pharmaceutical and chemical synthesis, with overall use subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 303.18
    methanol 656.82
    isopropanol 178.22
    water 518.99
    ethyl acetate 64.54
    n-propanol 172.86
    acetone 155.57
    n-butanol 115.8
    acetonitrile 270.0
    DMF 399.78
    toluene 12.02
    isobutanol 110.76
    1,4-dioxane 138.9
    methyl acetate 119.76
    THF 109.78
    2-butanone 80.25
    n-pentanol 49.07
    sec-butanol 115.51
    n-hexane 8.04
    ethylene glycol 337.06
    NMP 266.64
    cyclohexane 15.34
    DMSO 277.49
    n-butyl acetate 23.82
    n-octanol 26.05
    chloroform 262.05
    n-propyl acetate 27.73
    acetic acid 767.22
    dichloromethane 270.96
    cyclohexanone 80.52
    propylene glycol 155.46
    isopropyl acetate 23.91
    DMAc 258.32
    2-ethoxyethanol 123.31
    isopentanol 60.99
    n-heptane 9.06
    ethyl formate 87.93
    1,2-dichloroethane 112.5
    n-hexanol 36.41
    2-methoxyethanol 327.26
    isobutyl acetate 12.43
    tetrachloromethane 75.4
    n-pentyl acetate 18.14
    transcutol 164.28
    n-heptanol 22.25
    ethylbenzene 7.81
    MIBK 16.87
    2-propoxyethanol 79.91
    tert-butanol 142.66
    MTBE 43.88
    2-butoxyethanol 46.8
    propionic acid 239.91
    o-xylene 15.07
    formic acid 825.68
    diethyl ether 59.09
    m-xylene 9.28
    p-xylene 11.9
    chlorobenzene 32.63
    dimethyl carbonate 33.26
    n-octane 3.78
    formamide 698.47
    cyclopentanone 100.61
    2-pentanone 41.0
    anisole 28.04
    cyclopentyl methyl ether 42.48
    gamma-butyrolactone 155.77
    1-methoxy-2-propanol 145.82
    pyridine 116.97
    3-pentanone 42.55
    furfural 188.07
    n-dodecane 2.8
    diethylene glycol 135.56
    diisopropyl ether 10.09
    tert-amyl alcohol 95.73
    acetylacetone 44.01
    n-hexadecane 2.9
    acetophenone 30.52
    methyl propionate 69.75
    isopentyl acetate 17.81
    trichloroethylene 211.6
    n-nonanol 21.35
    cyclohexanol 86.96
    benzyl alcohol 40.65
    2-ethylhexanol 20.2
    isooctanol 17.08
    dipropyl ether 23.7
    1,2-dichlorobenzene 39.25
    ethyl lactate 28.48
    propylene carbonate 64.82
    n-methylformamide 334.04
    2-pentanol 54.67
    n-pentane 13.69
    1-propoxy-2-propanol 46.33
    1-methoxy-2-propyl acetate 24.4
    2-(2-methoxypropoxy) propanol 48.23
    mesitylene 7.0
    ε-caprolactone 76.51
    p-cymene 10.29
    epichlorohydrin 128.19
    1,1,1-trichloroethane 87.27
    2-aminoethanol 310.69
    morpholine-4-carbaldehyde 227.29
    sulfolane 154.85
    2,2,4-trimethylpentane 6.13
    2-methyltetrahydrofuran 78.32
    n-hexyl acetate 27.72
    isooctane 2.57
    2-(2-butoxyethoxy)ethanol 57.73
    sec-butyl acetate 13.58
    tert-butyl acetate 19.3
    decalin 4.69
    glycerin 267.73
    diglyme 107.61
    acrylic acid 297.0
    isopropyl myristate 10.07
    n-butyric acid 151.42
    acetyl acetate 42.29
    di(2-ethylhexyl) phthalate 16.4
    ethyl propionate 27.62
    nitromethane 569.62
    1,2-diethoxyethane 32.56
    benzonitrile 50.01
    trioctyl phosphate 11.43
    1-bromopropane 50.96
    gamma-valerolactone 147.5
    n-decanol 15.21
    triethyl phosphate 17.27
    4-methyl-2-pentanol 19.23
    propionitrile 114.59
    vinylene carbonate 77.48
    1,1,2-trichlorotrifluoroethane 210.59
    DMS 30.97
    cumene 7.85
    2-octanol 14.3
    2-hexanone 21.0
    octyl acetate 15.76
    limonene 16.1
    1,2-dimethoxyethane 125.27
    ethyl orthosilicate 16.14
    tributyl phosphate 13.8
    diacetone alcohol 41.37
    N,N-dimethylaniline 25.57
    acrylonitrile 180.44
    aniline 54.9
    1,3-propanediol 257.86
    bromobenzene 24.76
    dibromomethane 146.98
    1,1,2,2-tetrachloroethane 144.78
    2-methyl-cyclohexyl acetate 17.46
    tetrabutyl urea 22.52
    diisobutyl methanol 12.13
    2-phenylethanol 27.36
    styrene 12.01
    dioctyl adipate 19.65
    dimethyl sulfate 63.49
    ethyl butyrate 22.99
    methyl lactate 63.59
    butyl lactate 22.93
    diethyl carbonate 18.69
    propanediol butyl ether 48.73
    triethyl orthoformate 18.8
    p-tert-butyltoluene 9.6
    methyl 4-tert-butylbenzoate 33.12
    morpholine 187.53
    tert-butylamine 84.36
    n-dodecanol 11.79
    dimethoxymethane 106.53
    ethylene carbonate 54.1
    cyrene 45.09
    2-ethoxyethyl acetate 26.68
    2-ethylhexyl acetate 14.33
    1,2,4-trichlorobenzene 49.88
    4-methylpyridine 72.35
    dibutyl ether 17.49
    2,6-dimethyl-4-heptanol 12.13
    DEF 94.75
    dimethyl isosorbide 52.14
    tetrachloroethylene 156.2
    eugenol 39.39
    triacetin 37.78
    span 80 42.82
    1,4-butanediol 90.68
    1,1-dichloroethane 100.71
    2-methyl-1-pentanol 32.64
    methyl formate 199.4
    2-methyl-1-butanol 72.97
    n-decane 4.64
    butyronitrile 80.22
    3,7-dimethyl-1-octanol 20.09
    1-chlorooctane 13.69
    1-chlorotetradecane 5.69
    n-nonane 4.84
    undecane 3.43
    tert-butylcyclohexane 4.53
    cyclooctane 4.41
    cyclopentanol 113.64
    tetrahydropyran 77.5
    tert-amyl methyl ether 34.7
    2,5,8-trioxanonane 75.01
    1-hexene 18.41
    2-isopropoxyethanol 56.39
    2,2,2-trifluoroethanol 355.35
    methyl butyrate 40.12

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction