Flonicamid

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  • Identifiers

    CAS number
    158062-67-0

    Molecular formula
    C9H6F3N3O

    SMILES
    C1=CN=CC(=C1C(F)(F)F)C(=O)NCC#N

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 66.2%
    Savory 28.9%
    Cooling 23.76%
    Meaty 22.09%
    Bitter 19.13%
    Cooked 18.95%
    Animal 18.18%
    Sweet 18.17%
    Milky 17.36%
    Fishy 16.2%

     

    Flavor
    Bitter 74.75%
    Odorless 46.25%
    Bland 26.44%
    Mild 20.54%
    Sweet-like 19.17%
    Nitrile 18.95%
    Taco 17.84%
    Bread crust 17.78%
    Cedarleaf 17.64%
    Scallion 17.64%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    0.8

    pKa est.
    3.91 (weak acid)

    Molecular weight
    229.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Boiling point est.
    354°C

    Melting point expt.

    • 157.5 °C

    Flash point

    • 139.04 ˚C est.

    Solubility expt.

    • In water, 5.2X10+3 mg/L at 20 °C

  • Synonyms

    • Flonicamid
    • 158062-67-0
    • Flonicamid [ISO]
    • Aria
    • 3-Pyridinecarboxamide, N-(cyanomethyl)-4-(trifluoromethyl)-
    • N-(cyanomethyl)-4-(trifluoromethyl)nicotinamide
    • IKI 220
    • N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide
    • F 1785
    • BELEAF
    • TURBINE
    • UNII-9500W2Z53J
    • CHEBI:39291
    • HSDB 7937
    • FLONICAMID [MI]
    • 9500W2Z53J
    • N-(Cyanomethyl)-4-(trifluoromethyl)-3-pyridinecarboxamide
    • DTXSID8034611
    • IKI-220
    • n-cyanomethyl-4-trifluoromethylnicotinamide
    • n-cyanomethyl-4-(trifluoromethyl)nicotinamide
    • F-1785
    • MFCD07364026
    • 3-Pyridinecarboxamide,N-(cyanomethyl)-4-(trifluoromethyl)-
    • SCHEMBL26954
    • CHEMBL1882892
    • DTXCID6014611
    • GLXC-25868
    • BCP29996
    • AKOS015909866
    • FF28958
    • USEPA/OPP Pesticide Code: 128016
    • NCGC00163878-01
    • AS-75470
    • Flonicamid 100 microg/mL in Acetonitrile
    • DB-043376
    • HY-119649
    • CS-0077202
    • F1309
    • NS00000440
    • Flonicamid, PESTANAL(R), analytical standard
    • C18463
    • D95873
    • EN300-11783565
    • Q4328316
    • Z2050046071
    • 605-127-0
    • N-(Cyanomethyl)-4-(trifluoromethyl)nicotinamide N-Cyanomethyl-4-trifluoromethyl-3-pyridinecarboxamide
    • N-(cyanomethyl)-4-(trifluoromethyl)pyridine-3-carboxamide;3-Pyridinecarboxamide, N-(cyanomethyl)-4-(trifluoromethyl)-

  • Applications

    Flonicamid (CAS 158062-67-0) is a systemic insecticide used in agriculture to control sap-sucking pests such as aphids, whiteflies, and thrips on vegetables, fruits, and ornamental crops. It is typically applied as a foliar spray or greenhouse treatment to achieve plant uptake and systemic protection, and is commonly used in field and greenhouse production. In practice, it supports integrated pest management programs as a targeted tool for crops including tomatoes, cucumbers, peppers, apples, and other ornamentals, and may be formulated for soil application where appropriate, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 21.2
    methanol 44.28
    isopropanol 11.37
    water 1.8
    ethyl acetate 37.9
    n-propanol 11.3
    acetone 117.32
    n-butanol 8.41
    acetonitrile 80.21
    DMF 117.04
    toluene 14.11
    isobutanol 6.46
    1,4-dioxane 54.62
    methyl acetate 64.33
    THF 84.07
    2-butanone 55.92
    n-pentanol 9.42
    sec-butanol 8.66
    n-hexane 0.46
    ethylene glycol 12.19
    NMP 148.11
    cyclohexane 0.47
    DMSO 297.07
    n-butyl acetate 25.83
    n-octanol 10.55
    chloroform 18.36
    n-propyl acetate 33.4
    acetic acid 33.08
    dichloromethane 37.28
    cyclohexanone 42.05
    propylene glycol 5.13
    isopropyl acetate 23.26
    DMAc 157.5
    2-ethoxyethanol 43.11
    isopentanol 8.07
    n-heptane 1.22
    ethyl formate 30.75
    1,2-dichloroethane 34.75
    n-hexanol 10.88
    2-methoxyethanol 51.36
    isobutyl acetate 12.77
    tetrachloromethane 2.62
    n-pentyl acetate 25.37
    transcutol 64.37
    n-heptanol 11.39
    ethylbenzene 9.57
    MIBK 18.74
    2-propoxyethanol 39.07
    tert-butanol 17.06
    MTBE 15.76
    2-butoxyethanol 30.52
    propionic acid 17.26
    o-xylene 12.5
    formic acid 38.74
    diethyl ether 20.16
    m-xylene 9.14
    p-xylene 13.38
    chlorobenzene 13.65
    dimethyl carbonate 37.77
    n-octane 0.78
    formamide 93.43
    cyclopentanone 72.88
    2-pentanone 33.81
    anisole 32.5
    cyclopentyl methyl ether 21.62
    gamma-butyrolactone 98.79
    1-methoxy-2-propanol 27.82
    pyridine 56.37
    3-pentanone 32.88
    furfural 91.12
    n-dodecane 0.99
    diethylene glycol 37.78
    diisopropyl ether 5.54
    tert-amyl alcohol 12.3
    acetylacetone 61.01
    n-hexadecane 1.13
    acetophenone 43.93
    methyl propionate 38.53
    isopentyl acetate 19.45
    trichloroethylene 47.42
    n-nonanol 10.79
    cyclohexanol 7.0
    benzyl alcohol 21.25
    2-ethylhexanol 8.69
    isooctanol 8.91
    dipropyl ether 14.71
    1,2-dichlorobenzene 15.15
    ethyl lactate 18.59
    propylene carbonate 37.85
    n-methylformamide 63.35
    2-pentanol 6.01
    n-pentane 0.49
    1-propoxy-2-propanol 23.17
    1-methoxy-2-propyl acetate 32.18
    2-(2-methoxypropoxy) propanol 35.84
    mesitylene 5.68
    ε-caprolactone 39.71
    p-cymene 9.13
    epichlorohydrin 84.59
    1,1,1-trichloroethane 16.55
    2-aminoethanol 13.49
    morpholine-4-carbaldehyde 108.38
    sulfolane 119.19
    2,2,4-trimethylpentane 0.42
    2-methyltetrahydrofuran 38.47
    n-hexyl acetate 26.22
    isooctane 0.29
    2-(2-butoxyethoxy)ethanol 40.51
    sec-butyl acetate 18.24
    tert-butyl acetate 26.4
    decalin 0.7
    glycerin 11.26
    diglyme 85.62
    acrylic acid 21.7
    isopropyl myristate 14.38
    n-butyric acid 14.38
    acetyl acetate 33.66
    di(2-ethylhexyl) phthalate 16.46
    ethyl propionate 31.6
    nitromethane 156.53
    1,2-diethoxyethane 34.34
    benzonitrile 30.75
    trioctyl phosphate 11.58
    1-bromopropane 11.98
    gamma-valerolactone 85.17
    n-decanol 8.94
    triethyl phosphate 18.16
    4-methyl-2-pentanol 4.71
    propionitrile 30.25
    vinylene carbonate 33.4
    1,1,2-trichlorotrifluoroethane 44.38
    DMS 37.09
    cumene 6.93
    2-octanol 8.44
    2-hexanone 32.76
    octyl acetate 19.66
    limonene 9.41
    1,2-dimethoxyethane 88.38
    ethyl orthosilicate 15.01
    tributyl phosphate 12.96
    diacetone alcohol 29.97
    N,N-dimethylaniline 25.88
    acrylonitrile 51.9
    aniline 17.27
    1,3-propanediol 15.57
    bromobenzene 12.9
    dibromomethane 20.68
    1,1,2,2-tetrachloroethane 30.39
    2-methyl-cyclohexyl acetate 22.31
    tetrabutyl urea 24.24
    diisobutyl methanol 5.97
    2-phenylethanol 24.32
    styrene 11.86
    dioctyl adipate 21.82
    dimethyl sulfate 69.56
    ethyl butyrate 25.18
    methyl lactate 22.87
    butyl lactate 17.08
    diethyl carbonate 22.33
    propanediol butyl ether 17.65
    triethyl orthoformate 18.42
    p-tert-butyltoluene 7.87
    methyl 4-tert-butylbenzoate 37.44
    morpholine 45.36
    tert-butylamine 7.59
    n-dodecanol 7.27
    dimethoxymethane 76.92
    ethylene carbonate 27.27
    cyrene 42.68
    2-ethoxyethyl acetate 39.63
    2-ethylhexyl acetate 16.64
    1,2,4-trichlorobenzene 21.49
    4-methylpyridine 46.88
    dibutyl ether 12.25
    2,6-dimethyl-4-heptanol 5.97
    DEF 46.5
    dimethyl isosorbide 64.44
    tetrachloroethylene 21.64
    eugenol 37.39
    triacetin 37.16
    span 80 20.64
    1,4-butanediol 9.2
    1,1-dichloroethane 18.79
    2-methyl-1-pentanol 8.91
    methyl formate 66.97
    2-methyl-1-butanol 6.74
    n-decane 1.31
    butyronitrile 19.36
    3,7-dimethyl-1-octanol 8.64
    1-chlorooctane 5.94
    1-chlorotetradecane 3.31
    n-nonane 1.05
    undecane 1.14
    tert-butylcyclohexane 0.65
    cyclooctane 0.31
    cyclopentanol 10.76
    tetrahydropyran 22.19
    tert-amyl methyl ether 14.13
    2,5,8-trioxanonane 70.02
    1-hexene 3.03
    2-isopropoxyethanol 28.08
    2,2,2-trifluoroethanol 25.06
    methyl butyrate 35.69

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction