Ethylurea

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  • Identifiers

    CAS number
    625-52-5

    Molecular formula
    C3H8N2O

    SMILES
    CCNC(=O)N

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 51.76%
    Fishy 46.94%
    Cheesy 39.33%
    Meaty 32.78%
    Savory 29.99%
    Ripe 27.84%
    Pungent 23.25%
    Cooling 20.23%
    Cooked 19.01%
    Animal 17.06%

     

    Flavor
    Odorless 47.41%
    Sulfury 25.14%
    Mild 22.91%
    Acidic 22.03%
    Sour 21.6%
    Pungent 21.36%
    Mousy 20.84%
    Cooked 20.65%
    Soy 20.17%
    Yeast 19.92%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -0.7

    pKa est.
    7.64 (neutral)

    Molecular weight
    88.11 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    299°C

    Flash point

    • 107.58 ˚C est.

  • Synonyms

    • Ethylurea
    • 625-52-5
    • 1-Ethylurea
    • N-ETHYLUREA
    • Urea, ethyl-
    • NSC-53556
    • 7K14B03X18
    • DTXSID20873854
    • RefChem:921324
    • DTXCID3011929
    • 210-898-8
    • Urea, 1-ethyl-
    • ethyl urea
    • Urea, N-ethyl-
    • MFCD00007953
    • 9009-54-5
    • NSC53556
    • 1-Ethylurea; Ethylurea; NSC 53556
    • EINECS 210-898-8
    • NSC 53556
    • AI3-52220
    • Athylisoharnstoff
    • UNII-7K14B03X18
    • N-Ethylurea, 97%
    • ETHYLUREA, N-
    • SCHEMBL23881
    • SCHEMBL23882
    • SCHEMBL36467
    • SCHEMBL36468
    • SCHEMBL81515
    • SCHEMBL2889499
    • SCHEMBL11323087
    • STR01353
    • STL185700
    • AKOS000120949
    • SY049360
    • DB-054197
    • E0192
    • NS00043479
    • NS00112511
    • EN300-20604
    • D95291
    • F818026
    • Q26840850
    • InChI=1/C3H8N2O/c1-2-5-3(4)6/h2H2,1H3,(H3,4,5,6
    • 9009-54-5

  • Applications

    Ethylurea (CAS 625-52-5) is primarily employed as a chemical intermediate in organic synthesis, serving as a building block for the preparation of N-substituted urea derivatives and related compounds. In industry, it is commonly evaluated for pharmaceutical and agrochemical development, and as a precursor in specialty chemicals and polymer/urethane chemistry, including routes to urethane- or polyurea-containing materials. It is also used in research and development settings as a reagent or starting material for synthesis and characterization of derivatives. Overall, applications are largely as a reagent/precursor rather than a final active ingredient, and use is contingent on local regulations and formulation considerations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 139.16
    methanol 295.43
    isopropanol 66.04
    water 453.49
    ethyl acetate 19.46
    n-propanol 68.94
    acetone 59.52
    n-butanol 46.33
    acetonitrile 41.93
    DMF 249.88
    toluene 2.74
    isobutanol 40.22
    1,4-dioxane 39.65
    methyl acetate 29.03
    THF 84.25
    2-butanone 29.52
    n-pentanol 28.3
    sec-butanol 41.1
    n-hexane 1.26
    ethylene glycol 149.28
    NMP 190.64
    cyclohexane 0.73
    DMSO 216.69
    n-butyl acetate 10.52
    n-octanol 9.85
    chloroform 9.76
    n-propyl acetate 9.6
    acetic acid 316.56
    dichloromethane 11.14
    cyclohexanone 36.26
    propylene glycol 129.89
    isopropyl acetate 10.38
    DMAc 172.32
    2-ethoxyethanol 67.45
    isopentanol 26.89
    n-heptane 0.77
    ethyl formate 38.48
    1,2-dichloroethane 6.8
    n-hexanol 17.59
    2-methoxyethanol 159.54
    isobutyl acetate 6.19
    tetrachloromethane 2.77
    n-pentyl acetate 10.46
    transcutol 76.44
    n-heptanol 10.39
    ethylbenzene 1.18
    MIBK 10.33
    2-propoxyethanol 53.82
    tert-butanol 41.87
    MTBE 12.57
    2-butoxyethanol 30.27
    propionic acid 99.9
    o-xylene 2.85
    formic acid 386.38
    diethyl ether 11.12
    m-xylene 2.95
    p-xylene 2.19
    chlorobenzene 4.42
    dimethyl carbonate 12.81
    n-octane 0.42
    formamide 244.59
    cyclopentanone 62.36
    2-pentanone 19.27
    anisole 6.29
    cyclopentyl methyl ether 18.65
    gamma-butyrolactone 98.25
    1-methoxy-2-propanol 81.02
    pyridine 23.15
    3-pentanone 12.55
    furfural 90.98
    n-dodecane 0.38
    diethylene glycol 74.35
    diisopropyl ether 2.54
    tert-amyl alcohol 32.77
    acetylacetone 24.98
    n-hexadecane 0.4
    acetophenone 9.45
    methyl propionate 22.18
    isopentyl acetate 9.28
    trichloroethylene 12.07
    n-nonanol 8.53
    cyclohexanol 22.06
    benzyl alcohol 14.37
    2-ethylhexanol 7.14
    isooctanol 7.46
    dipropyl ether 5.16
    1,2-dichlorobenzene 4.33
    ethyl lactate 14.9
    propylene carbonate 44.12
    n-methylformamide 147.55
    2-pentanol 19.57
    n-pentane 1.3
    1-propoxy-2-propanol 27.34
    1-methoxy-2-propyl acetate 15.35
    2-(2-methoxypropoxy) propanol 26.93
    mesitylene 2.05
    ε-caprolactone 39.49
    p-cymene 2.03
    epichlorohydrin 47.14
    1,1,1-trichloroethane 5.0
    2-aminoethanol 153.82
    morpholine-4-carbaldehyde 115.99
    sulfolane 113.86
    2,2,4-trimethylpentane 0.84
    2-methyltetrahydrofuran 37.22
    n-hexyl acetate 13.62
    isooctane 0.52
    2-(2-butoxyethoxy)ethanol 33.25
    sec-butyl acetate 5.5
    tert-butyl acetate 9.95
    decalin 0.53
    glycerin 175.72
    diglyme 46.35
    acrylic acid 118.32
    isopropyl myristate 4.97
    n-butyric acid 74.11
    acetyl acetate 15.74
    di(2-ethylhexyl) phthalate 12.3
    ethyl propionate 8.66
    nitromethane 204.66
    1,2-diethoxyethane 12.23
    benzonitrile 12.58
    trioctyl phosphate 7.83
    1-bromopropane 4.33
    gamma-valerolactone 100.76
    n-decanol 6.04
    triethyl phosphate 6.16
    4-methyl-2-pentanol 9.14
    propionitrile 20.43
    vinylene carbonate 40.81
    1,1,2-trichlorotrifluoroethane 65.59
    DMS 13.6
    cumene 1.48
    2-octanol 6.57
    2-hexanone 10.8
    octyl acetate 8.1
    limonene 2.91
    1,2-dimethoxyethane 52.54
    ethyl orthosilicate 5.5
    tributyl phosphate 9.1
    diacetone alcohol 26.12
    N,N-dimethylaniline 6.32
    acrylonitrile 32.66
    aniline 13.89
    1,3-propanediol 120.43
    bromobenzene 2.46
    dibromomethane 5.94
    1,1,2,2-tetrachloroethane 10.61
    2-methyl-cyclohexyl acetate 7.83
    tetrabutyl urea 12.93
    diisobutyl methanol 3.74
    2-phenylethanol 12.11
    styrene 1.5
    dioctyl adipate 9.87
    dimethyl sulfate 33.45
    ethyl butyrate 7.51
    methyl lactate 35.09
    butyl lactate 15.9
    diethyl carbonate 5.97
    propanediol butyl ether 38.14
    triethyl orthoformate 6.7
    p-tert-butyltoluene 1.97
    methyl 4-tert-butylbenzoate 17.55
    morpholine 61.95
    tert-butylamine 15.5
    n-dodecanol 4.38
    dimethoxymethane 45.91
    ethylene carbonate 30.11
    cyrene 32.25
    2-ethoxyethyl acetate 16.0
    2-ethylhexyl acetate 6.89
    1,2,4-trichlorobenzene 6.49
    4-methylpyridine 21.45
    dibutyl ether 4.62
    2,6-dimethyl-4-heptanol 3.74
    DEF 36.68
    dimethyl isosorbide 32.99
    tetrachloroethylene 8.55
    eugenol 20.69
    triacetin 17.28
    span 80 25.91
    1,4-butanediol 54.2
    1,1-dichloroethane 6.27
    2-methyl-1-pentanol 19.33
    methyl formate 89.36
    2-methyl-1-butanol 29.67
    n-decane 0.6
    butyronitrile 21.46
    3,7-dimethyl-1-octanol 7.44
    1-chlorooctane 2.26
    1-chlorotetradecane 1.03
    n-nonane 0.58
    undecane 0.46
    tert-butylcyclohexane 0.66
    cyclooctane 0.31
    cyclopentanol 46.9
    tetrahydropyran 20.44
    tert-amyl methyl ether 10.76
    2,5,8-trioxanonane 37.91
    1-hexene 3.45
    2-isopropoxyethanol 32.18
    2,2,2-trifluoroethanol 112.82
    methyl butyrate 14.03

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction