Ethylenethiourea

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  • Identifiers

    CAS number
    96-45-7

    Molecular formula
    C3H6N2S

    SMILES
    C1CNC(=S)N1

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 45.7%
    Fishy 34.08%
    Nutty 33.59%
    Roasted 30.03%
    Popcorn 28.69%
    Meaty 27.21%
    Burnt 24.52%
    Pungent 22.33%
    Cooked 21.85%
    Sweet 20.53%

     

    Flavor
    Bitter 64.6%
    Roasted 26.8%
    Alkaline 21.5%
    Shrimp 21.13%
    Taco 20.6%
    Amine 20.48%
    Cereal 20.31%
    Nitrile 20.04%
    Rotten 19.83%
    Odorless 19.71%

     

    Odor impact est.
    Low

    Odor threshold

    • Odorless

  • Properties

    XLogP3-AA
    -0.7

    pKa est.
    7.96 (neutral)

    Molecular weight
    102.16 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Melting point expt.

    • 397 to 399 °F (NTP, 1992)
    • 203 °C
    • ETHYLENE THIOUREA (ETU) IS AVAILABLE IN USA AS WHITE CRYSTALS OR FINELY-GROUND POWDER WITH A MELTING POINT OF 192 °C. IT IS ALSO AVAILABLE IN USA & JAPAN AS A WHITE POWDER WITH A MELTING POINT ABOVE 195 °C. IT IS AVAILABLE IN USA AS WHITE POWDER CONSISTING OF 80% DISPERSION OF ETU IN OIL.
    • 194 °C
    • 392 °F

    Boiling point

    • 446 to 595 °F at 760 mmHg (NIOSH, 2024)
    • 446-595 °F

    Flash point

    • 102.02 ˚C est.
    • 486 °F (NTP, 1992)
    • 486 °F
    • 252 °C

    Solubility expt.

    • 1 to 5 mg/mL at 64 °F (NTP, 1992)
    • Soluble in ethanol; slightly soluble in dimethyl sulfoxide; insoluble in ethyl ether, benzene, chloroform
    • Moderately soluble in methanol, ethanol, ethylene glycol, pyridine; insoluble in acetone, ether, chloroform, benzene, ligroin
    • Soluble in ethanol; insoluble in ethyl ether and benzene.
    • Slightly soluble at room temperature in methanol, ethanol, acetic acid, naphtha.
    • 2 g/100 mL water at 30 °C; 9 g/100 mL water at 60 °C; 44 g/100 mL water at 90 °C
    • Solubility in water, g/100ml at 30 °C: 2 (moderate)
    • >15.3 [ug/mL] (The mean of the results at pH 7.4)
    • (86 °F): 2%

  • Synonyms

    • imidazolidine-2-thione
    • 2-Imidazolidinethione
    • 96-45-7
    • ETHYLENE THIOUREA
    • Ethylenethiourea
    • 2-Mercaptoimidazoline
    • Imidazolidinethione
    • Soxinol 22
    • Mercazin I
    • Warecure C
    • Rhenogran ETU
    • Pennac CRA
    • N,N'-Ethylenethiourea
    • Sanceller 22
    • Vulkacit NPV/C
    • Nocceler 22
    • 2-Imidazoline-2-thiol
    • 2-Mercapto-2-imidazoline
    • Robac 22
    • 1,3-Ethylenethiourea
    • Mercaptoimidazoline
    • Akrochem etu-22
    • Vulkacit NPV/C2
    • Mercozen
    • Imidazoline-2-thiol
    • Rhodanin S 62
    • 2-Thiol-dihydroglyoxaline
    • 1,3-Ethylene-2-thiourea
    • 4,5-dihydro-1H-imidazole-2-thiol
    • Aperochem ETU-22
    • Imidazoline-2(3H)-thione
    • NA-22-D
    • Ethylene thiouree
    • Sodium-22 neoprene accelerator
    • Imidazoline, 2-mercapto-
    • l'Ethylene thiouree
    • RCRA waste number U116
    • Tetrahydro-2H-imidazole-2-thione
    • 2-Merkaptoimidazolin
    • NA-22
    • Rodanin S-62
    • USAF EL-62
    • 4,5-Dihydroimidazole-2(3H)-thione
    • Thiourea, N,N'-(1,2-ethanediyl)-
    • Urea, 1,3-ethylene-2-thio-
    • NCI-C03372
    • 2-Thioimidazolidine
    • 24FOJ4N18S
    • Imidazole-2(3H)-thione, 4,5-dihydro-
    • 2-mercapto-4,5-dihydroimidazole
    • AI3-16292
    • NA 22
    • 2 Mercaptoimidazoline
    • 2-Imidazolidine-2-thione
    • RefChem:139155
    • 4,5-Dihydroimidazol-2(3h)-thione
    • 202-506-9
    • Ethylenethiocarbamide
    • N,N-Ethylenethiourea
    • Ethlenethiourea
    • 2-MERCAPTO IMIDAZOLINE
    • 12261-94-8
    • Ethylene thiourea (ETU)
    • 4,5-Dihydro-2-mercaptoimidazole
    • MFCD00005276
    • 2-Imidazolidinetione
    • MLS000069432
    • Cobalt(I I) nitrate
    • DTXSID5020601
    • ETU
    • C3H6N2S
    • SMR000059087
    • Ethylene thiourea 10 microg/mL in Acetonitrile
    • DTXCID90601
    • Rodanin S-62 [Czech]
    • Ethylene thiouree [French]
    • CAS-96-45-7
    • 2-Merkaptoimidazolin [Czech]
    • CCRIS 298
    • l'Ethylene thiouree [French]
    • 2-Imidazolidimethione
    • 2-Thioxoimidazolidine
    • HSDB 1643
    • EINECS 202-506-9
    • RCRA waste no. U116
    • UNII-24FOJ4N18S
    • Perkacit ETU
    • mancozeb TP1
    • 2-Imidozolidimethione
    • 2-Thionoimidazolidine
    • 2-imidazolidine-thione
    • n,n'-ethylene thiourea
    • Ethylenethiourea (ETU)
    • Akroform ETU-22 PM
    • imidazolidine, 2-thio-
    • Opera_ID_324
    • N(OO(3)AAoea)
    • EC 202-506-9
    • Ethylenethiourea (Standard)
    • SCHEMBL41176
    • 2-Imidazolidinethione, 98%
    • MLS002415731
    • BIDD:ER0692
    • CHEMBL11860
    • SCHEMBL137081
    • SCHEMBL243966
    • ETHYLENE THIOUREA [MI]
    • ETHYLENETHIOUREA [IARC]
    • orb1306749
    • SCHEMBL1682945
    • ETHYLENE THIOUREA [HSDB]
    • SCHEMBL20719507
    • BDBM62876
    • CHEBI:34750
    • cid_2723650
    • HMS2230P07
    • HMS3372A09
    • AAA09645
    • BB_SC-06569
    • HY-W010593R
    • MSK24013
    • STR00167
    • 2H-Imidazole-2-thione, tetrahydro-
    • Tox21_201294
    • Tox21_301034
    • SBB004362
    • STK369397
    • 96-45-7

  • Applications

    ETU is used as a sulfur vulcanization accelerator in rubber and elastomer processing. It serves as an intermediate in the synthesis of thiourea and urea derivatives in organic synthesis. It can be encountered as a degradation product of dithiocarbamate fungicides (e.g., mancozeb) used in agriculture, and is thus monitored for environmental and regulatory concerns. It has been studied for potential use as a crosslinking/curing agent in specialty polymer coatings and adhesives. Chemical name Ethylenethiourea, CAS 96-45-7

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 63.69
    methanol 170.95
    isopropanol 36.66
    water 34.44
    ethyl acetate 39.49
    n-propanol 39.97
    acetone 161.55
    n-butanol 27.96
    acetonitrile 76.67
    DMF 696.42
    toluene 6.97
    isobutanol 23.84
    1,4-dioxane 97.59
    methyl acetate 64.98
    THF 132.51
    2-butanone 68.47
    n-pentanol 18.18
    sec-butanol 24.04
    n-hexane 0.28
    ethylene glycol 92.94
    NMP 345.69
    cyclohexane 0.99
    DMSO 614.77
    n-butyl acetate 18.27
    n-octanol 11.57
    chloroform 55.48
    n-propyl acetate 18.29
    acetic acid 166.54
    dichloromethane 42.32
    cyclohexanone 71.62
    propylene glycol 76.69
    isopropyl acetate 19.02
    DMAc 450.41
    2-ethoxyethanol 63.16
    isopentanol 17.5
    n-heptane 1.08
    ethyl formate 48.54
    1,2-dichloroethane 26.59
    n-hexanol 16.64
    2-methoxyethanol 155.18
    isobutyl acetate 11.64
    tetrachloromethane 8.81
    n-pentyl acetate 17.7
    transcutol 101.2
    n-heptanol 12.48
    ethylbenzene 2.1
    MIBK 17.2
    2-propoxyethanol 57.06
    tert-butanol 33.68
    MTBE 17.18
    2-butoxyethanol 38.57
    propionic acid 74.16
    o-xylene 5.93
    formic acid 164.82
    diethyl ether 17.98
    m-xylene 5.15
    p-xylene 3.96
    chlorobenzene 16.49
    dimethyl carbonate 45.91
    n-octane 0.51
    formamide 196.04
    cyclopentanone 138.49
    2-pentanone 36.97
    anisole 17.41
    cyclopentyl methyl ether 30.12
    gamma-butyrolactone 144.89
    1-methoxy-2-propanol 95.27
    pyridine 71.76
    3-pentanone 32.93
    furfural 165.35
    n-dodecane 0.65
    diethylene glycol 89.77
    diisopropyl ether 4.1
    tert-amyl alcohol 24.06
    acetylacetone 66.87
    n-hexadecane 0.73
    acetophenone 26.85
    methyl propionate 53.5
    isopentyl acetate 14.44
    trichloroethylene 66.87
    n-nonanol 10.94
    cyclohexanol 21.75
    benzyl alcohol 24.99
    2-ethylhexanol 9.11
    isooctanol 9.19
    dipropyl ether 10.4
    1,2-dichlorobenzene 16.61
    ethyl lactate 24.72
    propylene carbonate 58.04
    n-methylformamide 232.67
    2-pentanol 14.05
    n-pentane 0.59
    1-propoxy-2-propanol 38.51
    1-methoxy-2-propyl acetate 33.94
    2-(2-methoxypropoxy) propanol 39.31
    mesitylene 3.54
    ε-caprolactone 51.75
    p-cymene 4.43
    epichlorohydrin 86.11
    1,1,1-trichloroethane 23.92
    2-aminoethanol 82.95
    morpholine-4-carbaldehyde 259.62
    sulfolane 229.61
    2,2,4-trimethylpentane 0.62
    2-methyltetrahydrofuran 49.53
    n-hexyl acetate 19.34
    isooctane 0.43
    2-(2-butoxyethoxy)ethanol 46.96
    sec-butyl acetate 10.49
    tert-butyl acetate 17.63
    decalin 0.59
    glycerin 149.15
    diglyme 86.88
    acrylic acid 103.34
    isopropyl myristate 8.69
    n-butyric acid 54.61
    acetyl acetate 34.77
    di(2-ethylhexyl) phthalate 16.32
    ethyl propionate 17.43
    nitromethane 312.33
    1,2-diethoxyethane 24.45
    benzonitrile 28.62
    trioctyl phosphate 10.84
    1-bromopropane 8.48
    gamma-valerolactone 181.51
    n-decanol 8.59
    triethyl phosphate 12.19
    4-methyl-2-pentanol 7.69
    propionitrile 37.61
    vinylene carbonate 62.18
    1,1,2-trichlorotrifluoroethane 136.95
    DMS 28.53
    cumene 2.18
    2-octanol 7.53
    2-hexanone 18.42
    octyl acetate 13.41
    limonene 6.62
    1,2-dimethoxyethane 80.59
    ethyl orthosilicate 9.9
    tributyl phosphate 12.16
    diacetone alcohol 36.98
    N,N-dimethylaniline 14.69
    acrylonitrile 71.93
    aniline 27.98
    1,3-propanediol 69.77
    bromobenzene 11.46
    dibromomethane 19.17
    1,1,2,2-tetrachloroethane 58.19
    2-methyl-cyclohexyl acetate 14.24
    tetrabutyl urea 19.14
    diisobutyl methanol 6.14
    2-phenylethanol 21.2
    styrene 3.6
    dioctyl adipate 16.51
    dimethyl sulfate 105.62
    ethyl butyrate 15.48
    methyl lactate 65.86
    butyl lactate 22.71
    diethyl carbonate 12.75
    propanediol butyl ether 42.43
    triethyl orthoformate 13.54
    p-tert-butyltoluene 4.68
    methyl 4-tert-butylbenzoate 28.98
    morpholine 105.33
    tert-butylamine 13.67
    n-dodecanol 6.72
    dimethoxymethane 119.95
    ethylene carbonate 44.41
    cyrene 50.62
    2-ethoxyethyl acetate 30.07
    2-ethylhexyl acetate 11.43
    1,2,4-trichlorobenzene 26.44
    4-methylpyridine 49.66
    dibutyl ether 7.25
    2,6-dimethyl-4-heptanol 6.14
    DEF 78.58
    dimethyl isosorbide 57.72
    tetrachloroethylene 35.49
    eugenol 33.98
    triacetin 32.27
    span 80 35.01
    1,4-butanediol 34.16
    1,1-dichloroethane 25.47
    2-methyl-1-pentanol 12.48
    methyl formate 151.66
    2-methyl-1-butanol 17.9
    n-decane 0.89
    butyronitrile 26.69
    3,7-dimethyl-1-octanol 10.39
    1-chlorooctane 4.06
    1-chlorotetradecane 2.18
    n-nonane 0.74
    undecane 0.74
    tert-butylcyclohexane 0.55
    cyclooctane 0.42
    cyclopentanol 40.85
    tetrahydropyran 39.28
    tert-amyl methyl ether 13.88
    2,5,8-trioxanonane 72.31
    1-hexene 1.46
    2-isopropoxyethanol 35.23
    2,2,2-trifluoroethanol 89.16
    methyl butyrate 24.82

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction