Ethylene Chlorohydrin

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  • Identifiers

    CAS number
    107-07-3

    Molecular formula
    C2H5ClO

    SMILES
    C(CCl)O

    Safety labels

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fragrance
    Odorless 49.27%
    Alcoholic 48.03%
    Fishy 37.14%
    Sweet 35.25%
    Oily 32.69%
    Ethereal 31.38%
    Solvent 30.59%
    Fermented 29.81%
    Pungent 22.95%
    Musty 22.06%

     

    Flavor
    Odorless 52.38%
    Fishy 27.54%
    Bitter 26.66%
    Alcoholic 26.19%
    Pungent 25.9%
    Sulfurous 24.28%
    Sweet 23.94%
    Very slight 22.79%
    Sweet-like 22.78%
    Soup 20.72%

     

    Odor impact est.
    Medium

    Odor threshold

    • Odor Threshold Low: 0.4 [mmHg]. Odor threshold from CHEMINFO

  • Properties

    XLogP3-AA
    -0.1

    pKa est.
    6.66 (neutral)

    Molecular weight
    80.51 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra fast

    Melting point expt.

    • -89.5 °F (EPA, 1998)
    • -67.5 °C
    • -67 °C
    • -90 °F

    Boiling point

    • 262 °F at 760 mmHg (EPA, 1998)
    • 128-130 °C @ 760 MM HG
    • 128-130 °C
    • 262 °F

    Flash point

    • 56.35 ˚C est.
    • 140 °F (EPA, 1998)
    • 40 °C
    • 105 °F (40 °C) (open cup)
    • 60 °C c.c.
    • 140 °F

    Solubility expt.

    • greater than or equal to 100 mg/mL at 66 °F (NTP, 1992)
    • SOL IN ALL PROPORTIONS IN WATER, ALC, ORG SOLVENTS; SLIGHTLY SOL IN ETHER
    • SOL IN VARIOUS RESINS
    • Infinitely soluble in aqueous solution (1X10+6 mg/l @ 25 °C)
    • Solubility in water: miscible
    • Miscible

  • Synonyms

    • 2-chloroethanol
    • Ethylene chlorohydrin
    • 107-07-3
    • Ethanol, 2-chloro-
    • Glycol chlorohydrin
    • 2-Chloroethyl alcohol
    • Chloroethanol
    • Glycol monochlorohydrin
    • 2-Monochloroethanol
    • Ethylchlorohydrin
    • 2-Chlorethanol
    • 2-Chloro-1-ethanol
    • Glycomonochlorhydrin
    • 2-Hydroxyethyl chloride
    • beta-Chloroethyl alcohol
    • Ethylene chlorhydrin
    • Ethene, chlorohydrin
    • 2-Chloorethanol
    • 2-Chloraethanol
    • 2-Cloroetanolo
    • beta-Chloroethanol
    • Aethylenechlorhydrin
    • Glicol monocloridrina
    • 2-Chloro-1-hydroxyethane
    • Ethyleen-chloorhydrine
    • Glycolmonochloorhydrine
    • Ethylene glycol, chlorohydrin
    • delta-Chloroethanol
    • NCI-C50135
    • beta-Hydroxyethyl chloride
    • 2-CHLORO-ETHANOL
    • 2-Chloorethanol [Dutch]
    • 2-Chlorethanol [German]
    • Monochlorhydrine du glycol
    • 2-Chloraethanol [German]
    • 2-Cloroetanolo [Italian]
    • .beta.-Chloroethyl alcohol
    • Chloroethylowy alkohol
    • Aethylenechlorhydrin [German]
    • CCRIS 859
    • Chloroalcohol
    • Ethyleen-chloorhydrine [Dutch]
    • Glycolmonochloorhydrine [Dutch]
    • HSDB 426
    • Chloroethylowy alkohol [Polish]
    • Glicol monocloridrina [Italian]
    • NSC 122289
    • Ethanol, chloro-
    • Monochlorhydrine du glycol [French]
    • EINECS 203-459-7
    • UN1135
    • BRN 0878139
    • .beta.-Chloroethanol
    • 753N66IHAN
    • DTXSID1021877
    • CHEBI:28200
    • AI3-52326
    • 1-chloro-2-hydroxyethane
    • MFCD00002829
    • delta-Chloroethanolchloroethylowy alkohol [Polish]
    • NSC-122289
    • delta-Chloroethanolchloroethylowy alkohol
    • .beta.-Hydroxyethyl chloride
    • DTXCID601877
    • 2-CHLOROETHANOL [HSDB]
    • 59826-67-4
    • EC 203-459-7
    • ETHYLENE CHLOROHYDRIN [MI]
    • 4-01-00-01372 (Beilstein Handbook Reference)
    • 2-Chlorethanol (German)
    • 2-Cloroetanolo (Italian)
    • Aethylenechlorhydrin (German)
    • Ethyleen-chloorhydrine (Dutch)
    • Glycolmonochloorhydrine (Dutch)
    • Chloroethylowy alkohol (Polish)
    • Glicol monocloridrina (Italian)
    • 2-CHLOORETHANOL (DUTCH)
    • 2-CHLORAETHANOL (GERMAN)
    • Monochlorhydrine du glycol (French)
    • 2 Chlorethanol
    • Ethylenechlorhydrin
    • 2-Chloro Ethanol
    • 2 Chloroethyl Alcohol
    • Chlorohydrin, Ethylene
    • Alcohol, 2-Chloroethyl
    • chloroethanols
    • UNII-753N66IHAN
    • 2chloroethanol
    • 2Chloorethanol
    • 2Chloraethanol
    • 2Chlorethanol
    • 2Cloroetanolo
    • 2Chloro1ethanol
    • deltaChloroethanol
    • 2Monochloroethanol
    • 2-chloranylethanol
    • Ethanol, 2chloro
    • ethylenechlorohydrin
    • ethylenechlorohydrine
    • Ethyleenchloorhydrine
    • 2Chloroethyl alcohol
    • 2-choroethan-1-ol
    • ethylene chlorohydrine
    • 2-chloroethan-1-ol
    • 2Chloro1hydroxyethane
    • 2Hydroxyethyl chloride
    • betaChloroethyl alcohol
    • 2-Chloroethanol (ethylene chlorohydrin)
    • 2-chloro-ethan-1-ol
    • CH2ClCH2OH
    • betaHydroxyethyl chloride
    • buta-1,3-diene-1,1,4-tricarboxylic acid
    • 2-Chloroethanol, 99%
    • ETHENE CHLOROHYDRIN
    • 2-Chloroethanol (OSHA)
    • bmse000360
    • WLN: Q2G
    • Pesticide Code: 600502
    • CHEMBL191244
    • CHEBI:23141
    • 868 - Ethylene oxide in spices
    • SEA06762
    • Tox21_300043
    • ArgoGel(TM)-Cl, 1 % cross-linked
    • BBL011477
    • Ethylene chlorohydrin (ACGIH:OSHA)
    • NSC122289
    • STL146589

  • Applications

    Ethylene chlorohydrin is primarily used as a reactive intermediate in organic synthesis to introduce a 2-chloroethyl group, enabling downstream formation of monoethanolamine and related ethylenediamine derivatives. It serves as a building block for ethanolamine-based surfactants and for epoxy resin systems that use amine hardeners. In polymer and specialty chemical formulations it is used to prepare chlorohydrin derivatives and other reactive intermediates for coatings, adhesives, and specialty solvents. Overall, its role is as an intermediate rather than a final product, and applications may vary with process conditions and regulatory requirements.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 504.46
    methanol 1011.66
    isopropanol 270.44
    water 392.04
    ethyl acetate 44.01
    n-propanol 294.62
    acetone 261.93
    n-butanol 192.13
    acetonitrile 151.72
    DMF 975.49
    toluene 6.61
    isobutanol 156.54
    1,4-dioxane 161.59
    methyl acetate 80.12
    THF 215.24
    2-butanone 103.63
    n-pentanol 110.41
    sec-butanol 151.19
    n-hexane 4.37
    ethylene glycol 501.78
    NMP 494.66
    cyclohexane 10.06
    DMSO 1083.21
    n-butyl acetate 58.29
    n-octanol 42.26
    chloroform 46.35
    n-propyl acetate 47.73
    acetic acid 873.38
    dichloromethane 56.18
    cyclohexanone 148.74
    propylene glycol 310.95
    isopropyl acetate 24.42
    DMAc 477.34
    2-ethoxyethanol 269.98
    isopentanol 108.07
    n-heptane 10.62
    ethyl formate 90.45
    1,2-dichloroethane 47.86
    n-hexanol 87.79
    2-methoxyethanol 518.46
    isobutyl acetate 27.63
    tetrachloromethane 13.76
    n-pentyl acetate 33.83
    transcutol 404.07
    n-heptanol 44.73
    ethylbenzene 5.06
    MIBK 30.42
    2-propoxyethanol 190.67
    tert-butanol 216.76
    MTBE 45.69
    2-butoxyethanol 116.0
    propionic acid 269.6
    o-xylene 9.29
    formic acid 854.84
    diethyl ether 39.92
    m-xylene 7.12
    p-xylene 9.28
    chlorobenzene 15.43
    dimethyl carbonate 30.44
    n-octane 3.21
    formamide 745.49
    cyclopentanone 187.92
    2-pentanone 63.97
    anisole 26.82
    cyclopentyl methyl ether 60.16
    gamma-butyrolactone 196.26
    1-methoxy-2-propanol 251.25
    pyridine 94.74
    3-pentanone 42.93
    furfural 211.86
    n-dodecane 2.58
    diethylene glycol 286.04
    diisopropyl ether 10.59
    tert-amyl alcohol 127.26
    acetylacetone 71.23
    n-hexadecane 2.7
    acetophenone 41.73
    methyl propionate 54.45
    isopentyl acetate 43.16
    trichloroethylene 74.78
    n-nonanol 34.96
    cyclohexanol 123.61
    benzyl alcohol 56.64
    2-ethylhexanol 43.62
    isooctanol 33.02
    dipropyl ether 45.1
    1,2-dichlorobenzene 17.16
    ethyl lactate 55.74
    propylene carbonate 76.89
    n-methylformamide 521.69
    2-pentanol 78.9
    n-pentane 6.17
    1-propoxy-2-propanol 140.49
    1-methoxy-2-propyl acetate 56.76
    2-(2-methoxypropoxy) propanol 114.72
    mesitylene 6.38
    ε-caprolactone 114.27
    p-cymene 12.03
    epichlorohydrin 133.84
    1,1,1-trichloroethane 22.74
    2-aminoethanol 533.08
    morpholine-4-carbaldehyde 410.46
    sulfolane 318.78
    2,2,4-trimethylpentane 3.58
    2-methyltetrahydrofuran 101.34
    n-hexyl acetate 43.95
    isooctane 2.5
    2-(2-butoxyethoxy)ethanol 150.42
    sec-butyl acetate 21.55
    tert-butyl acetate 29.23
    decalin 3.26
    glycerin 453.22
    diglyme 258.7
    acrylic acid 295.85
    isopropyl myristate 18.44
    n-butyric acid 203.3
    acetyl acetate 30.07
    di(2-ethylhexyl) phthalate 32.01
    ethyl propionate 28.97
    nitromethane 579.5
    1,2-diethoxyethane 70.79
    benzonitrile 45.79
    trioctyl phosphate 25.17
    1-bromopropane 20.01
    gamma-valerolactone 267.14
    n-decanol 25.92
    triethyl phosphate 28.52
    4-methyl-2-pentanol 32.35
    propionitrile 79.68
    vinylene carbonate 79.04
    1,1,2-trichlorotrifluoroethane 237.43
    DMS 35.93
    cumene 6.13
    2-octanol 25.83
    2-hexanone 50.71
    octyl acetate 28.76
    limonene 22.82
    1,2-dimethoxyethane 239.05
    ethyl orthosilicate 27.05
    tributyl phosphate 30.54
    diacetone alcohol 92.23
    N,N-dimethylaniline 31.66
    acrylonitrile 134.69
    aniline 43.89
    1,3-propanediol 436.04
    bromobenzene 9.3
    dibromomethane 32.6
    1,1,2,2-tetrachloroethane 67.52
    2-methyl-cyclohexyl acetate 38.5
    tetrabutyl urea 54.45
    diisobutyl methanol 25.33
    2-phenylethanol 49.14
    styrene 7.47
    dioctyl adipate 41.33
    dimethyl sulfate 72.98
    ethyl butyrate 44.03
    methyl lactate 85.61
    butyl lactate 58.91
    diethyl carbonate 28.23
    propanediol butyl ether 142.15
    triethyl orthoformate 38.32
    p-tert-butyltoluene 12.12
    methyl 4-tert-butylbenzoate 55.06
    morpholine 277.47
    tert-butylamine 92.85
    n-dodecanol 20.9
    dimethoxymethane 158.55
    ethylene carbonate 60.37
    cyrene 111.95
    2-ethoxyethyl acetate 47.77
    2-ethylhexyl acetate 32.97
    1,2,4-trichlorobenzene 24.18
    4-methylpyridine 61.81
    dibutyl ether 26.3
    2,6-dimethyl-4-heptanol 25.33
    DEF 146.97
    dimethyl isosorbide 126.57
    tetrachloroethylene 58.59
    eugenol 74.53
    triacetin 64.21
    span 80 112.52
    1,4-butanediol 205.94
    1,1-dichloroethane 27.04
    2-methyl-1-pentanol 66.32
    methyl formate 252.66
    2-methyl-1-butanol 110.89
    n-decane 3.69
    butyronitrile 70.65
    3,7-dimethyl-1-octanol 35.77
    1-chlorooctane 11.98
    1-chlorotetradecane 5.71
    n-nonane 3.56
    undecane 2.94
    tert-butylcyclohexane 3.37
    cyclooctane 2.85
    cyclopentanol 187.15
    tetrahydropyran 98.36
    tert-amyl methyl ether 35.44
    2,5,8-trioxanonane 203.46
    1-hexene 12.35
    2-isopropoxyethanol 136.29
    2,2,2-trifluoroethanol 262.38
    methyl butyrate 54.6

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction