Ethyl L-asparaginate

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  • Identifiers

    CAS number
    24184-58-5

    Molecular formula
    C6H12N2O3

    SMILES
    CCOC(=O)[C@H](CC(=O)N)N

  • Odor profile

    Fragrance
    Odorless 48.45%
    Sweet 37.3%
    Savory 29.04%
    Fruity 28.8%
    Buttery 22.53%
    Meaty 22.18%
    Grape 21.97%
    Milky 21.2%
    Caramellic 20.79%
    Cooked 18.41%

     

    Flavor
    Odorless 48.26%
    Fruity 32.16%
    Mild 28.35%
    Very mild 25.45%
    Bland 23.65%
    Bitter 23.34%
    Yeast 21.39%
    Sweet-like 20.83%
    Cooked 19.72%
    Orange flower 19.61%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -1.5

    pKa est.
    6.07 (neutral)

    Molecular weight
    160.17 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    329°C

    Flash point

    • 141.06 ˚C est.

  • Synonyms

    • Ethyl L-asparaginate
    • 24184-58-5
    • ethyl (2S)-2,4-diamino-4-oxobutanoate
    • Asparagine, ethyl ester
    • EINECS 246-068-7
    • SCHEMBL1178957
    • DTXSID60178890
    • ZTCCUHKCQDSJPK-BYPYZUCNSA-N
    • NS00027582
    • EN300-7696591
    • ETHYL (2S)-2-AMINO-3-CARBAMOYLPROPANOATE

  • Applications

    Ethyl L-asparaginate (CAS 24184-58-5) is primarily used as a protected amino acid ester and as a chiral building block in pharmaceutical and biotechnological synthesis. It serves as an intermediate in organic synthesis, enabling the preparation of aspartate-based derivatives and peptides in peptide chemistry. In research and development, it may be used as a starting material for the synthesis of aspartate derivatives for fine chemicals and can participate in projects in the agrochemical field. It can also act as a precursor or building block in limited polymer or materials applications, such as bio-based polymers, where the ester group enables controlled reactivity. Subject to local regulations and formulation limits, it is typically handled in controlled laboratory environments.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 8.66
    methanol 35.04
    isopropanol 2.68
    water 167.31
    ethyl acetate 1.23
    n-propanol 3.61
    acetone 3.16
    n-butanol 2.34
    acetonitrile 2.93
    DMF 71.09
    toluene 0.45
    isobutanol 2.53
    1,4-dioxane 4.06
    methyl acetate 1.7
    THF 7.67
    2-butanone 2.07
    n-pentanol 1.71
    sec-butanol 2.4
    n-hexane 0.18
    ethylene glycol 29.18
    NMP 107.66
    cyclohexane 0.16
    DMSO 185.93
    n-butyl acetate 1.5
    n-octanol 1.01
    chloroform 1.07
    n-propyl acetate 1.2
    acetic acid 62.31
    dichloromethane 1.86
    cyclohexanone 7.45
    propylene glycol 21.08
    isopropyl acetate 1.01
    DMAc 81.65
    2-ethoxyethanol 15.16
    isopentanol 2.61
    n-heptane 0.12
    ethyl formate 7.7
    1,2-dichloroethane 1.34
    n-hexanol 1.53
    2-methoxyethanol 31.78
    isobutyl acetate 0.81
    tetrachloromethane 0.58
    n-pentyl acetate 1.04
    transcutol 18.43
    n-heptanol 1.05
    ethylbenzene 0.53
    MIBK 1.59
    2-propoxyethanol 8.8
    tert-butanol 4.18
    MTBE 1.14
    2-butoxyethanol 4.63
    propionic acid 11.87
    o-xylene 0.98
    formic acid 195.68
    diethyl ether 0.57
    m-xylene 0.63
    p-xylene 0.84
    chlorobenzene 0.78
    dimethyl carbonate 2.72
    n-octane 0.07
    formamide 100.67
    cyclopentanone 10.87
    2-pentanone 1.44
    anisole 1.94
    cyclopentyl methyl ether 2.25
    gamma-butyrolactone 20.94
    1-methoxy-2-propanol 11.57
    pyridine 3.58
    3-pentanone 1.42
    furfural 42.55
    n-dodecane 0.05
    diethylene glycol 23.12
    diisopropyl ether 0.29
    tert-amyl alcohol 4.26
    acetylacetone 4.11
    n-hexadecane 0.06
    acetophenone 4.16
    methyl propionate 2.01
    isopentyl acetate 1.94
    trichloroethylene 2.53
    n-nonanol 0.97
    cyclohexanol 2.67
    benzyl alcohol 4.26
    2-ethylhexanol 1.16
    isooctanol 1.0
    dipropyl ether 0.7
    1,2-dichlorobenzene 1.29
    ethyl lactate 4.36
    propylene carbonate 14.12
    n-methylformamide 33.42
    2-pentanol 1.02
    n-pentane 0.12
    1-propoxy-2-propanol 4.93
    1-methoxy-2-propyl acetate 3.81
    2-(2-methoxypropoxy) propanol 9.31
    mesitylene 0.57
    ε-caprolactone 9.36
    p-cymene 0.71
    epichlorohydrin 8.66
    1,1,1-trichloroethane 0.69
    2-aminoethanol 27.56
    morpholine-4-carbaldehyde 50.93
    sulfolane 66.28
    2,2,4-trimethylpentane 0.12
    2-methyltetrahydrofuran 3.37
    n-hexyl acetate 1.58
    isooctane 0.07
    2-(2-butoxyethoxy)ethanol 8.53
    sec-butyl acetate 0.79
    tert-butyl acetate 1.8
    decalin 0.16
    glycerin 56.29
    diglyme 15.53
    acrylic acid 21.06
    isopropyl myristate 0.69
    n-butyric acid 9.17
    acetyl acetate 2.23
    di(2-ethylhexyl) phthalate 3.14
    ethyl propionate 1.29
    nitromethane 44.39
    1,2-diethoxyethane 1.63
    benzonitrile 3.12
    trioctyl phosphate 1.67
    1-bromopropane 0.44
    gamma-valerolactone 31.31
    n-decanol 0.71
    triethyl phosphate 2.61
    4-methyl-2-pentanol 0.96
    propionitrile 1.61
    vinylene carbonate 13.23
    1,1,2-trichlorotrifluoroethane 28.98
    DMS 2.87
    cumene 0.62
    2-octanol 0.64
    2-hexanone 1.31
    octyl acetate 1.02
    limonene 0.89
    1,2-dimethoxyethane 15.32
    ethyl orthosilicate 2.07
    tributyl phosphate 2.12
    diacetone alcohol 6.34
    N,N-dimethylaniline 2.74
    acrylonitrile 4.05
    aniline 1.84
    1,3-propanediol 20.85
    bromobenzene 0.55
    dibromomethane 0.96
    1,1,2,2-tetrachloroethane 2.37
    2-methyl-cyclohexyl acetate 2.71
    tetrabutyl urea 3.67
    diisobutyl methanol 0.82
    2-phenylethanol 2.97
    styrene 0.52
    dioctyl adipate 2.04
    dimethyl sulfate 14.6
    ethyl butyrate 1.64
    methyl lactate 9.19
    butyl lactate 3.78
    diethyl carbonate 1.74
    propanediol butyl ether 9.01
    triethyl orthoformate 1.96
    p-tert-butyltoluene 0.67
    methyl 4-tert-butylbenzoate 5.43
    morpholine 6.03
    tert-butylamine 1.51
    n-dodecanol 0.52
    dimethoxymethane 7.01
    ethylene carbonate 8.34
    cyrene 20.49
    2-ethoxyethyl acetate 2.34
    2-ethylhexyl acetate 1.43
    1,2,4-trichlorobenzene 1.81
    4-methylpyridine 3.96
    dibutyl ether 0.54
    2,6-dimethyl-4-heptanol 0.82
    DEF 7.36
    dimethyl isosorbide 16.51
    tetrachloroethylene 2.31
    eugenol 6.91
    triacetin 4.31
    span 80 6.5
    1,4-butanediol 10.5
    1,1-dichloroethane 0.5
    2-methyl-1-pentanol 2.35
    methyl formate 26.13
    2-methyl-1-butanol 2.86
    n-decane 0.08
    butyronitrile 1.78
    3,7-dimethyl-1-octanol 1.17
    1-chlorooctane 0.27
    1-chlorotetradecane 0.13
    n-nonane 0.08
    undecane 0.06
    tert-butylcyclohexane 0.14
    cyclooctane 0.09
    cyclopentanol 4.15
    tetrahydropyran 1.24
    tert-amyl methyl ether 1.51
    2,5,8-trioxanonane 13.93
    1-hexene 0.37
    2-isopropoxyethanol 6.16
    2,2,2-trifluoroethanol 28.69
    methyl butyrate 2.58

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction