Eremanthin

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    37936-58-6

    Molecular formula
    C15H18O2

    SMILES
    CC1=CC[C@@H]2[C@@H]([C@@H]3[C@H]1CCC3=C)OC(=O)C2=C

  • Odor profile

    Fragrance
    Spicy 45.91%
    Woody 40.24%
    Green 39.93%
    Nutty 36.92%
    Mint 33.07%
    Sweet 31.24%
    Herbal 29.34%
    Tobacco 23.92%
    Coumarinic 22.7%
    Coconut 22.51%

     

    Flavor
    Bitter 81.11%
    Lovage 20.71%
    Cedarleaf 20.62%
    Basil 20.57%
    Nitrile 19.12%
    Shrimp 18.84%
    Fenugreek 18.69%
    Ripe apricot 18.66%
    Leaves 18.62%
    Alkaline 18.5%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    2.6

    pKa est.
    7.35 (neutral)

    Molecular weight
    230.3 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    445°C

    Flash point

    • 139.8 ˚C est.

  • Synonyms

    • Eremanthin
    • 37936-58-6
    • Vanillosmin
    • CHEBI:4815
    • (3aS,6aR,9aR,9bS)-6-methyl-3,9-dimethylidene-4,6a,7,8,9a,9b-hexahydro-3aH-azuleno[4,5-b]furan-2-one
    • NSC321215
    • NSC 321215
    • CHEMBL451364
    • SCHEMBL9516039
    • DTXSID50191371
    • BWRZDLYJNURUHS-XUXIUFHCSA-N
    • NSC-321215
    • NCI60_002782
    • C09406
    • Q27106489
    • Azuleno(4,5-b)furan-2(3H)-one, 3a,4,6a,7,8,9,9a,9b-octahydro-6-methyl-3,9-bis(methylene)-, (3aS-(3aalpha,6aalpha,9aalpha,9bbeta))-
    • Azuleno[4, 3a,4,6a,7,8,9,9a,9b-octahydro-6-methyl-3,9-bis(methylene)-, [3aS-(3a.alpha.,6a.alpha.,9a.alpha.,9b.beta.)]-

  • Applications

    Eremanthin (CAS 37936-58-6) is a natural sesquiterpene lactone that is primarily used in research and development contexts as a lead or intermediate for the synthesis of related compounds and as a test substrate for assessing biological activity. It is also studied in agricultural and biotechnological contexts as a bioactive candidate for pest-management research or product development. In analytical and materials-science settings, eremanthin can serve as a reference standard or as a component in isolation and purification workflows. Overall, its applications are exploratory and context-dependent, with use constrained by local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 178.33
    methanol 200.26
    isopropanol 261.96
    water 0.49
    ethyl acetate 298.15
    n-propanol 240.62
    acetone 400.71
    n-butanol 240.21
    acetonitrile 225.7
    DMF 667.58
    toluene 525.73
    isobutanol 227.26
    1,4-dioxane 668.92
    methyl acetate 364.68
    THF 871.23
    2-butanone 528.28
    n-pentanol 144.18
    sec-butanol 226.81
    n-hexane 4.03
    ethylene glycol 40.28
    NMP 447.59
    cyclohexane 21.34
    DMSO 366.38
    n-butyl acetate 231.88
    n-octanol 70.93
    chloroform 1644.73
    n-propyl acetate 213.2
    acetic acid 174.12
    dichloromethane 1250.38
    cyclohexanone 662.93
    propylene glycol 64.56
    isopropyl acetate 232.97
    DMAc 493.14
    2-ethoxyethanol 220.69
    isopentanol 261.11
    n-heptane 5.46
    ethyl formate 242.04
    1,2-dichloroethane 604.45
    n-hexanol 157.82
    2-methoxyethanol 343.42
    isobutyl acetate 166.89
    tetrachloromethane 147.43
    n-pentyl acetate 171.57
    transcutol 770.33
    n-heptanol 89.43
    ethylbenzene 168.46
    MIBK 230.26
    2-propoxyethanol 283.8
    tert-butanol 252.84
    MTBE 192.54
    2-butoxyethanol 193.64
    propionic acid 193.96
    o-xylene 228.11
    formic acid 64.22
    diethyl ether 164.46
    m-xylene 280.92
    p-xylene 232.86
    chlorobenzene 481.47
    dimethyl carbonate 165.73
    n-octane 3.72
    formamide 150.07
    cyclopentanone 755.58
    2-pentanone 342.37
    anisole 293.24
    cyclopentyl methyl ether 292.02
    gamma-butyrolactone 669.88
    1-methoxy-2-propanol 303.45
    pyridine 866.0
    3-pentanone 256.13
    furfural 607.39
    n-dodecane 5.35
    diethylene glycol 225.19
    diisopropyl ether 68.45
    tert-amyl alcohol 191.56
    acetylacetone 365.79
    n-hexadecane 6.47
    acetophenone 306.06
    methyl propionate 261.04
    isopentyl acetate 241.26
    trichloroethylene 1336.74
    n-nonanol 71.0
    cyclohexanol 260.14
    benzyl alcohol 295.15
    2-ethylhexanol 97.14
    isooctanol 83.82
    dipropyl ether 69.45
    1,2-dichlorobenzene 395.14
    ethyl lactate 113.02
    propylene carbonate 379.74
    n-methylformamide 283.02
    2-pentanol 167.19
    n-pentane 7.91
    1-propoxy-2-propanol 194.11
    1-methoxy-2-propyl acetate 259.35
    2-(2-methoxypropoxy) propanol 205.95
    mesitylene 145.89
    ε-caprolactone 473.16
    p-cymene 85.79
    epichlorohydrin 851.75
    1,1,1-trichloroethane 500.96
    2-aminoethanol 92.01
    morpholine-4-carbaldehyde 561.57
    sulfolane 537.16
    2,2,4-trimethylpentane 9.99
    2-methyltetrahydrofuran 499.66
    n-hexyl acetate 208.7
    isooctane 9.67
    2-(2-butoxyethoxy)ethanol 267.13
    sec-butyl acetate 167.68
    tert-butyl acetate 208.26
    decalin 17.83
    glycerin 105.71
    diglyme 484.03
    acrylic acid 177.99
    isopropyl myristate 87.56
    n-butyric acid 289.41
    acetyl acetate 219.07
    di(2-ethylhexyl) phthalate 118.23
    ethyl propionate 167.37
    nitromethane 355.31
    1,2-diethoxyethane 235.36
    benzonitrile 468.33
    trioctyl phosphate 73.57
    1-bromopropane 277.67
    gamma-valerolactone 765.65
    n-decanol 54.83
    triethyl phosphate 87.65
    4-methyl-2-pentanol 122.39
    propionitrile 265.65
    vinylene carbonate 416.28
    1,1,2-trichlorotrifluoroethane 416.35
    DMS 231.42
    cumene 107.13
    2-octanol 65.28
    2-hexanone 219.38
    octyl acetate 105.9
    limonene 95.97
    1,2-dimethoxyethane 390.03
    ethyl orthosilicate 84.01
    tributyl phosphate 88.86
    diacetone alcohol 225.38
    N,N-dimethylaniline 174.78
    acrylonitrile 361.58
    aniline 430.87
    1,3-propanediol 178.79
    bromobenzene 526.38
    dibromomethane 722.48
    1,1,2,2-tetrachloroethane 898.68
    2-methyl-cyclohexyl acetate 153.82
    tetrabutyl urea 111.51
    diisobutyl methanol 69.45
    2-phenylethanol 254.08
    styrene 207.51
    dioctyl adipate 128.07
    dimethyl sulfate 221.92
    ethyl butyrate 159.86
    methyl lactate 142.74
    butyl lactate 147.92
    diethyl carbonate 122.19
    propanediol butyl ether 182.27
    triethyl orthoformate 112.17
    p-tert-butyltoluene 77.42
    methyl 4-tert-butylbenzoate 205.77
    morpholine 625.14
    tert-butylamine 138.93
    n-dodecanol 43.88
    dimethoxymethane 381.67
    ethylene carbonate 347.84
    cyrene 225.83
    2-ethoxyethyl acetate 265.61
    2-ethylhexyl acetate 185.44
    1,2,4-trichlorobenzene 467.67
    4-methylpyridine 792.5
    dibutyl ether 78.32
    2,6-dimethyl-4-heptanol 69.45
    DEF 297.51
    dimethyl isosorbide 329.21
    tetrachloroethylene 546.72
    eugenol 221.18
    triacetin 215.44
    span 80 167.9
    1,4-butanediol 79.5
    1,1-dichloroethane 640.58
    2-methyl-1-pentanol 168.47
    methyl formate 241.08
    2-methyl-1-butanol 216.02
    n-decane 7.78
    butyronitrile 267.08
    3,7-dimethyl-1-octanol 95.42
    1-chlorooctane 47.08
    1-chlorotetradecane 23.31
    n-nonane 5.74
    undecane 6.28
    tert-butylcyclohexane 14.83
    cyclooctane 7.41
    cyclopentanol 276.63
    tetrahydropyran 521.26
    tert-amyl methyl ether 129.9
    2,5,8-trioxanonane 313.49
    1-hexene 36.02
    2-isopropoxyethanol 175.98
    2,2,2-trifluoroethanol 102.03
    methyl butyrate 237.61

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Laurel leaf (Turkey) 4 8006-78-8 Laurus nobilis L., fam. Lauraceae 0.1%