Ascorbyl Stearate

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  • Identifiers

    CAS number
    10605-09-1

    Molecular formula
    C24H42O7

    SMILES
    CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]([C@@H]1C(=C(C(=O)O1)O)O)O

    Safety labels

  • Odor profile

    Fragrance
    Fatty 49.05%
    Waxy 48.82%
    Odorless 44.32%
    Oily 32.41%
    Milky 25.33%
    Buttery 24.1%
    Lactonic 23.75%
    Creamy 23.68%
    Dairy 21.88%
    Savory 21.38%

     

    Flavor
    Waxy 40.05%
    Bland 38.64%
    Fatty 36.28%
    Mild 34.8%
    Odorless 33.53%
    Oily 32.49%
    Faint 25.76%
    Slightly waxy 22.99%
    Bay oil 22.15%
    Creamy 21.82%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    7.3

    pKa est.
    1.45 (strong acid)

    Molecular weight
    442.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    694°C

    Flash point

    • 200.8 ˚C est.

  • Synonyms

    • Ascorbyl stearate
    • L-Ascorbic acid, 6-octadecanoate
    • L-Ascorbic acid monostearate
    • vitamin c stearate
    • INS NO.305
    • E-305
    • INS-305
    • L-ASCORBYL 6-OCTADECANOATE
    • ASCORBYL STEARATE [USP-RS]
    • STEARIC ACID, 6-ESTER WITH L-ASCORBIC ACID
    • ASCORBYL STEARATE (USP-RS)
    • L-Ascorbic acid, 6-octadecanoate (9CI)
    • RefChem:560185
    • ASCORBYL STEARATE [INCI]
    • 246-944-9
    • 2-(3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl)-2-hydroxyethyl octadecanoate
    • L-Ascorbyl 6-Stearate
    • 10605-09-1
    • 25395-66-8
    • L-Ascorbic acid 6-stearate
    • (S)-2-((R)-3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl)-2-hydroxyethyl stearate
    • 6-O-Stearoyl-L-ascorbic Acid
    • L-Ascorbicacid6-stearate
    • 7Z1QT341US
    • [(2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2H-furan-2-yl]-2-hydroxyethyl] octadecanoate
    • MFCD00059739
    • 6-(Stearoyloxy)-L-ascorbic acid
    • L-ASCORBIC ACID, 6-STEARATE
    • (2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2,5-dihydrofuran-2-yl]-2-hydroxyethyl octadecanoate
    • UNII-7Z1QT341US
    • EINECS 234-231-5
    • 6-Ascorbyl stearate
    • L-Ascorbyl-6-stearate
    • L-Stearoyl-6-ascorbic Acid
    • SCHEMBL16202
    • CHEMBL218804
    • DTXSID00894148
    • CHEBI:138822
    • LITUBCVUXPBCGA-WMZHIEFXSA-N
    • AKOS022172048
    • HY-W127738
    • BP-44439
    • E305
    • FS163221
    • A0617
    • CS-0185932
    • C20340
    • D88295
    • 395A668
    • Q286793
    • L-Ascorbic acid 6-stearate, analytical reference material
    • [(2S)-2-[(2R)-3,4-dihydroxy-5-oxo-2H-furan-2-yl]-2-hydroxy-ethyl] octadecanoate
    • 10605-09-1

  • Applications

    Ascorbyl Stearate (CAS 10605-09-1) is widely used in cosmetics and personal care as a vitamin C derivative that provides antioxidant protection and skin-conditioning/emollient properties in creams, lotions, and other topical formulations. It is also used as a stabilizer/antioxidant additive in certain polymers and coatings to help resist oxidative degradation. In pharmaceutical and topical dosage forms, it can function as an excipient or emollient component, contributing to formulation stability and skin feel. Additionally, it may be evaluated for use in specialized cosmetic or coating systems where lipid-soluble vitamin C esters are desirable, within regulatory and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 21.92
    methanol 46.21
    isopropanol 19.57
    water 2.32
    ethyl acetate 42.92
    n-propanol 23.84
    acetone 87.54
    n-butanol 17.28
    acetonitrile 24.97
    DMF 199.0
    toluene 10.52
    isobutanol 16.89
    1,4-dioxane 57.1
    methyl acetate 49.81
    THF 153.91
    2-butanone 62.5
    n-pentanol 18.85
    sec-butanol 22.92
    n-hexane 1.55
    ethylene glycol 8.18
    NMP 300.21
    cyclohexane 3.92
    DMSO 421.93
    n-butyl acetate 23.71
    n-octanol 17.14
    chloroform 65.58
    n-propyl acetate 37.85
    acetic acid 103.2
    dichloromethane 79.81
    cyclohexanone 113.4
    propylene glycol 16.07
    isopropyl acetate 38.5
    DMAc 363.7
    2-ethoxyethanol 68.01
    isopentanol 16.43
    n-heptane 1.43
    ethyl formate 32.53
    1,2-dichloroethane 62.88
    n-hexanol 10.95
    2-methoxyethanol 77.36
    isobutyl acetate 21.82
    tetrachloromethane 18.03
    n-pentyl acetate 51.52
    transcutol 173.43
    n-heptanol 17.85
    ethylbenzene 9.02
    MIBK 30.31
    2-propoxyethanol 43.27
    tert-butanol 29.81
    MTBE 27.9
    2-butoxyethanol 61.43
    propionic acid 54.65
    o-xylene 14.02
    formic acid 51.14
    diethyl ether 18.33
    m-xylene 9.49
    p-xylene 12.26
    chlorobenzene 16.82
    dimethyl carbonate 41.35
    n-octane 1.56
    formamide 107.56
    cyclopentanone 154.08
    2-pentanone 45.36
    anisole 21.51
    cyclopentyl methyl ether 51.57
    gamma-butyrolactone 186.45
    1-methoxy-2-propanol 65.52
    pyridine 53.3
    3-pentanone 44.45
    furfural 113.14
    n-dodecane 1.04
    diethylene glycol 31.88
    diisopropyl ether 8.47
    tert-amyl alcohol 32.76
    acetylacetone 95.7
    n-hexadecane 1.2
    acetophenone 41.81
    methyl propionate 51.78
    isopentyl acetate 25.86
    trichloroethylene 112.48
    n-nonanol 17.35
    cyclohexanol 30.28
    benzyl alcohol 25.2
    2-ethylhexanol 9.2
    isooctanol 16.22
    dipropyl ether 12.33
    1,2-dichlorobenzene 22.93
    ethyl lactate 33.84
    propylene carbonate 88.18
    n-methylformamide 81.1
    2-pentanol 13.97
    n-pentane 1.26
    1-propoxy-2-propanol 34.75
    1-methoxy-2-propyl acetate 43.03
    2-(2-methoxypropoxy) propanol 48.44
    mesitylene 6.98
    ε-caprolactone 111.35
    p-cymene 6.98
    epichlorohydrin 128.17
    1,1,1-trichloroethane 57.73
    2-aminoethanol 21.35
    morpholine-4-carbaldehyde 162.36
    sulfolane 356.56
    2,2,4-trimethylpentane 1.89
    2-methyltetrahydrofuran 73.38
    n-hexyl acetate 49.53
    isooctane 0.82
    2-(2-butoxyethoxy)ethanol 64.01
    sec-butyl acetate 27.94
    tert-butyl acetate 49.85
    decalin 2.79
    glycerin 32.67
    diglyme 140.31
    acrylic acid 51.3
    isopropyl myristate 14.32
    n-butyric acid 63.4
    acetyl acetate 43.0
    di(2-ethylhexyl) phthalate 18.5
    ethyl propionate 36.41
    nitromethane 177.65
    1,2-diethoxyethane 45.32
    benzonitrile 22.15
    trioctyl phosphate 15.56
    1-bromopropane 19.61
    gamma-valerolactone 197.86
    n-decanol 11.01
    triethyl phosphate 21.72
    4-methyl-2-pentanol 9.74
    propionitrile 19.77
    vinylene carbonate 68.84
    1,1,2-trichlorotrifluoroethane 146.19
    DMS 46.11
    cumene 7.84
    2-octanol 15.15
    2-hexanone 36.2
    octyl acetate 22.21
    limonene 10.39
    1,2-dimethoxyethane 87.16
    ethyl orthosilicate 21.07
    tributyl phosphate 18.75
    diacetone alcohol 73.05
    N,N-dimethylaniline 22.2
    acrylonitrile 29.49
    aniline 21.42
    1,3-propanediol 28.95
    bromobenzene 15.46
    dibromomethane 41.5
    1,1,2,2-tetrachloroethane 115.45
    2-methyl-cyclohexyl acetate 26.99
    tetrabutyl urea 29.02
    diisobutyl methanol 6.79
    2-phenylethanol 19.08
    styrene 9.18
    dioctyl adipate 28.28
    dimethyl sulfate 116.78
    ethyl butyrate 24.18
    methyl lactate 50.01
    butyl lactate 52.0
    diethyl carbonate 17.78
    propanediol butyl ether 51.12
    triethyl orthoformate 24.19
    p-tert-butyltoluene 7.04
    methyl 4-tert-butylbenzoate 60.82
    morpholine 83.94
    tert-butylamine 13.52
    n-dodecanol 7.32
    dimethoxymethane 80.1
    ethylene carbonate 59.88
    cyrene 67.59
    2-ethoxyethyl acetate 74.66
    2-ethylhexyl acetate 20.09
    1,2,4-trichlorobenzene 34.63
    4-methylpyridine 39.27
    dibutyl ether 16.92
    2,6-dimethyl-4-heptanol 6.79
    DEF 82.08
    dimethyl isosorbide 85.9
    tetrachloroethylene 76.35
    eugenol 49.28
    triacetin 79.46
    span 80 41.12
    1,4-butanediol 18.26
    1,1-dichloroethane 43.52
    2-methyl-1-pentanol 18.91
    methyl formate 59.69
    2-methyl-1-butanol 19.18
    n-decane 2.25
    butyronitrile 16.7
    3,7-dimethyl-1-octanol 13.47
    1-chlorooctane 10.95
    1-chlorotetradecane 3.54
    n-nonane 2.05
    undecane 1.44
    tert-butylcyclohexane 2.09
    cyclooctane 1.65
    cyclopentanol 43.7
    tetrahydropyran 50.34
    tert-amyl methyl ether 28.72
    2,5,8-trioxanonane 84.2
    1-hexene 5.31
    2-isopropoxyethanol 45.86
    2,2,2-trifluoroethanol 69.54
    methyl butyrate 51.51

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction