Arginine Hydrochloride

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  • Identifiers

    CAS number
    1119-34-2

    Molecular formula
    C6H15ClN4O2

    SMILES
    C(C[C@@H](C(=O)O)N)CN=C(N)N.Cl

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 66.09%
    Fishy 42.03%
    Savory 34.29%
    Meaty 30.49%
    Cooling 24.27%
    Cheesy 21.49%
    Ripe 18.95%
    Cooked 18.81%
    Sweet 17.46%
    Animal 16.87%

     

    Flavor
    Odorless 53.47%
    Mild 31.91%
    Bitter 31.82%
    Bland 28.17%
    Faint 23.88%
    Roasted 21.98%
    Cooked 21.73%
    Sweet-like 20.98%
    Nitrile 20.44%
    Yeast 20.43%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    6.9 (neutral)

    Molecular weight
    210.66 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    387°C

    Flash point

    • 175.66 ˚C est.

  • Synonyms

    • L-Arginine hydrochloride
    • 1119-34-2
    • Arginine Hydrochloride
    • L-ARGININE HCL
    • L-Arginine monohydrochloride
    • Arginine HCl
    • 15595-35-4
    • H-Arg-OH.HCl
    • R-Gene
    • Argamine
    • Argivene
    • Detoxargin
    • Levargin
    • Minophagen A
    • Arginine monohydrochloride
    • Tivortin
    • R-gene 10
    • L-(+)-Arginine monohydrochloride
    • Arginine, hydrochloride, L-
    • MFCD00064550
    • UNII-F7LTH1E20Y
    • (S)-2-Amino-5-guanidinopentanoic acid hydrochloride
    • L-Arginine (hydrochloride)
    • NSC 7914
    • EINECS 214-275-1
    • Arginine monochloride
    • F7LTH1E20Y
    • NSC 203450
    • L(+)-Arginine hydrochloride
    • L-Arginine, monohydrochloride
    • AI3-18300
    • NSC-7914
    • NSC-203450
    • EC 214-275-1
    • L-Arginine, hydrochloride (1:1)
    • L-Arginine, monohydrochloride, L-
    • ARGININE, L-, HYDROCHLORIDE
    • (2S)-2-amino-5-carbamimidamidopentanoic acid hydrochloride
    • Hydrochloride, arginine
    • L-(+)-Arginine Hydrochloride
    • L-arginine, hydrochloride
    • (2S)-2-amino-5-(diaminomethylideneamino)pentanoic acid;hydrochloride
    • MFCD00166393
    • (S)-(+)-2-Amino-5-[(aminoiminomethyl)amino]pentanoic acid monohydrochloride
    • ARGININE HYDROCHLORIDE (MART.)
    • ARGININE HYDROCHLORIDE [MART.]
    • ARGININE HYDROCHLORIDE (USP-RS)
    • ARGININE HYDROCHLORIDE [USP-RS]
    • R-gene (TN)
    • (+)-L-Arginine hydrochloride
    • ARGININE HYDROCHLORIDE (EP MONOGRAPH)
    • ARGININE HYDROCHLORIDE [EP MONOGRAPH]
    • L-Arginine hydrochloride (VAN)
    • NSC203450
    • ARGININE HYDROCHLORIDE (USP MONOGRAPH)
    • ARGININE HYDROCHLORIDE [USP MONOGRAPH]
    • Arginine Hydrochloride [USAN:JAN]
    • C6H15ClN4O2
    • NSC7914
    • (S)-(+)-Arginine hydrochloride
    • L-Argininexhydrochloride
    • nBu-PArg(20)*HCl
    • nBu-PArg(50)*HCl
    • l-arginine monochlorhydrate
    • nBu-PArg(100)*HCl
    • Argininine monohydrochloride
    • SCHEMBL44977
    • Arginine hydrochloride (USP)
    • HY-N0455AR
    • CHEMBL1200381
    • CHEBI:31235
    • HY-N0455A
    • DTXSID20883650
    • L-Arginine hydrochloride (JP17)
    • ARGININE HYDROCHLORIDE [MI]
    • ARGININE HYDROCHLORIDE [USAN]
    • CCG-43265
    • s3174
    • ARGININE HYDROCHLORIDE [VANDF]
    • AKOS015906195
    • AKOS015924214
    • L-ARGININE HYDROCHLORIDE [JAN]
    • ARGININE HYDROCHLORIDE [WHO-DD]
    • CS-2046
    • DS-2054
    • FA15785
    • L-Arginine (hydrochloride) (Standard)
    • AC-23975
    • L-ARGININE MONOHYDROCHLORIDE [FCC]
    • ARGININE HYDROCHLORIDE [ORANGE BOOK]
    • DB-029943
    • A0528
    • CS-0368604
    • NS00085581
    • D01126
    • D70773
    • EN300-249105
    • Arginine Hydrochloride (L-Arginine Hydrochloride)
    • L-Arginine monohydrochloride, Vetec(TM), 98.5%
    • SR-01000075479-3
    • Q27277776
    • L-Arginine hydrochloride, SAJ special grade, >=99.0%
    • L-Arginine monohydrochloride, BioUltra, >=99.5% (AT)
    • L-Arginine monohydrochloride, Vetec(TM) reagent grade, >=98%
    • L-Arginine monohydrochloride, reagent grade, >=98% (HPLC), powder
    • Arginine hydrochloride, British Pharmacopoeia (BP) Reference Standard
    • Arginine hydrochloride, European Pharmacopoeia (EP) Reference Standard
    • L-Arginine monohydrochloride, certified reference material, TraceCERT(R)
    • Arginine Hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material
    • 214-275-1
    • L-Arginine monohydrochloride, not synthetic, meets EP, JP, USP testing specifications, suitable for cell culture, 98.5-101.0%

  • Applications

    Arginine Hydrochloride (CAS 1119-34-2) serves as a source of the amino acid L-arginine in pharmaceutical and biotechnology formulations, and is commonly used as a building block for peptide synthesis and other amino acid derivatives in drug manufacturing. In nutrition and food processing, it is employed as a supply of arginine in dietary supplements and fortified products. In agriculture, it is used as a feed additive to augment arginine nutrition in livestock. In cosmetics and personal care, it is incorporated as an amino acid ingredient to support formulation pH and conditioning properties. In industrial manufacturing, it may function as a nutrient source in fermentation and cell-culture media and as a chemical intermediate for specialty compounds.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.03
    methanol 0.14
    isopropanol 0.02
    water 67.99
    ethyl acetate 0.05
    n-propanol 0.02
    acetone 0.02
    n-butanol 0.02
    acetonitrile 0.02
    DMF 0.68
    toluene 0.07
    isobutanol 0.02
    1,4-dioxane 0.04
    methyl acetate 0.03
    THF 0.09
    2-butanone 0.03
    n-pentanol 0.02
    sec-butanol 0.02
    n-hexane 0.05
    ethylene glycol 0.92
    NMP 7.44
    cyclohexane 0.03
    DMSO 4.09
    n-butyl acetate 0.05
    n-octanol 0.02
    chloroform 0.05
    n-propyl acetate 0.03
    acetic acid 1.28
    dichloromethane 0.06
    cyclohexanone 0.19
    propylene glycol 0.48
    isopropyl acetate 0.05
    DMAc 2.23
    2-ethoxyethanol 0.21
    isopentanol 0.03
    n-heptane 0.05
    ethyl formate 0.09
    1,2-dichloroethane 0.04
    n-hexanol 0.06
    2-methoxyethanol 0.39
    isobutyl acetate 0.02
    tetrachloromethane 0.07
    n-pentyl acetate 0.04
    transcutol 0.45
    n-heptanol 0.06
    ethylbenzene 0.06
    MIBK 0.05
    2-propoxyethanol 0.35
    tert-butanol 0.04
    MTBE 0.02
    2-butoxyethanol 0.23
    propionic acid 0.26
    o-xylene 0.18
    formic acid 17.5
    diethyl ether 0.02
    m-xylene 0.13
    p-xylene 0.09
    chlorobenzene 0.03
    dimethyl carbonate 0.16
    n-octane 0.02
    formamide 4.19
    cyclopentanone 0.23
    2-pentanone 0.04
    anisole 0.04
    cyclopentyl methyl ether 0.17
    gamma-butyrolactone 0.55
    1-methoxy-2-propanol 0.3
    pyridine 0.1
    3-pentanone 0.07
    furfural 1.65
    n-dodecane 0.01
    diethylene glycol 1.46
    diisopropyl ether 0.02
    tert-amyl alcohol 0.07
    acetylacetone 0.14
    n-hexadecane 0.01
    acetophenone 0.14
    methyl propionate 0.1
    isopentyl acetate 0.07
    trichloroethylene 0.1
    n-nonanol 0.03
    cyclohexanol 0.09
    benzyl alcohol 0.1
    2-ethylhexanol 0.06
    isooctanol 0.05
    dipropyl ether 0.06
    1,2-dichlorobenzene 0.07
    ethyl lactate 0.23
    propylene carbonate 0.45
    n-methylformamide 0.43
    2-pentanol 0.02
    n-pentane 0.02
    1-propoxy-2-propanol 0.24
    1-methoxy-2-propyl acetate 0.2
    2-(2-methoxypropoxy) propanol 0.5
    mesitylene 0.13
    ε-caprolactone 0.28
    p-cymene 0.1
    epichlorohydrin 0.12
    1,1,1-trichloroethane 0.04
    2-aminoethanol 0.45
    morpholine-4-carbaldehyde 1.79
    sulfolane 4.93
    2,2,4-trimethylpentane 0.02
    2-methyltetrahydrofuran 0.07
    n-hexyl acetate 0.04
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 0.37
    sec-butyl acetate 0.03
    tert-butyl acetate 0.08
    decalin 0.03
    glycerin 4.98
    diglyme 0.5
    acrylic acid 0.79
    isopropyl myristate 0.02
    n-butyric acid 0.24
    acetyl acetate 0.09
    di(2-ethylhexyl) phthalate 0.13
    ethyl propionate 0.06
    nitromethane 0.56
    1,2-diethoxyethane 0.04
    benzonitrile 0.07
    trioctyl phosphate 0.08
    1-bromopropane 0.02
    gamma-valerolactone 0.73
    n-decanol 0.02
    triethyl phosphate 0.16
    4-methyl-2-pentanol 0.04
    propionitrile 0.02
    vinylene carbonate 0.41
    1,1,2-trichlorotrifluoroethane 2.4
    DMS 0.12
    cumene 0.07
    2-octanol 0.03
    2-hexanone 0.03
    octyl acetate 0.03
    limonene 0.11
    1,2-dimethoxyethane 0.17
    ethyl orthosilicate 0.15
    tributyl phosphate 0.09
    diacetone alcohol 0.33
    N,N-dimethylaniline 0.15
    acrylonitrile 0.06
    aniline 0.13
    1,3-propanediol 0.22
    bromobenzene 0.03
    dibromomethane 0.04
    1,1,2,2-tetrachloroethane 0.12
    2-methyl-cyclohexyl acetate 0.11
    tetrabutyl urea 0.16
    diisobutyl methanol 0.07
    2-phenylethanol 0.13
    styrene 0.04
    dioctyl adipate 0.05
    dimethyl sulfate 1.08
    ethyl butyrate 0.07
    methyl lactate 0.77
    butyl lactate 0.21
    diethyl carbonate 0.06
    propanediol butyl ether 0.35
    triethyl orthoformate 0.12
    p-tert-butyltoluene 0.1
    methyl 4-tert-butylbenzoate 0.44
    morpholine 0.06
    tert-butylamine 0.02
    n-dodecanol 0.02
    dimethoxymethane 0.16
    ethylene carbonate 0.22
    cyrene 1.66
    2-ethoxyethyl acetate 0.07
    2-ethylhexyl acetate 0.06
    1,2,4-trichlorobenzene 0.09
    4-methylpyridine 0.11
    dibutyl ether 0.02
    2,6-dimethyl-4-heptanol 0.07
    DEF 0.23
    dimethyl isosorbide 1.16
    tetrachloroethylene 0.19
    eugenol 0.52
    triacetin 0.16
    span 80 0.45
    1,4-butanediol 0.14
    1,1-dichloroethane 0.02
    2-methyl-1-pentanol 0.03
    methyl formate 0.36
    2-methyl-1-butanol 0.03
    n-decane 0.01
    butyronitrile 0.02
    3,7-dimethyl-1-octanol 0.03
    1-chlorooctane 0.01
    1-chlorotetradecane 0.01
    n-nonane 0.01
    undecane 0.01
    tert-butylcyclohexane 0.02
    cyclooctane 0.03
    cyclopentanol 0.11
    tetrahydropyran 0.03
    tert-amyl methyl ether 0.05
    2,5,8-trioxanonane 0.7
    1-hexene 0.04
    2-isopropoxyethanol 0.11
    2,2,2-trifluoroethanol 2.07
    methyl butyrate 0.07

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction