Aminoguanidine bicarbonate

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  • Identifiers

    CAS number
    2582-30-1

    Molecular formula
    C2H8N4O3

    SMILES
    C(=NN)(N)N.C(=O)(O)O

    Safety labels

    Irritant
    Irritant

    Health Hazard
    Health

    Environmental Hazard
    Environmental

  • Odor profile

    Fragrance
    Odorless 55.74%
    Fishy 54.65%
    Cheesy 26.75%
    Pungent 25.86%
    Ripe 25.64%
    Meaty 18.2%
    Savory 17.41%
    Cooked 15.85%
    Sulfurous 14.91%
    Radish 14.32%

     

    Flavor
    Odorless 32.75%
    Bitter 32.51%
    Roasted 22.57%
    Sulfur 21.82%
    Mild 21.01%
    Mustard 20.94%
    Formyl 20.13%
    Nitrile 19.95%
    Mousy 19.93%
    Rotten 19.76%

     

    Odor impact est.
    Odorless

  • Properties

    pKa est.
    7.5 (neutral)

    Molecular weight
    136.11 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    272°C

    Flash point

    • 96.64 ˚C est.

  • Synonyms

    • Aminoguanidine bicarbonate
    • 2582-30-1
    • Aminoguanidine hydrogen carbonate
    • Aminoguanidinium bicarbonate
    • Aminoguanidine carbonate (1:1)
    • Aminoguanidium hydrogen carbonate
    • Aminoguanidinium hydrogen carbonate
    • N1-Aminoguanidine carbonate (1:1)
    • 1-Aminoguanidine bicarbonate
    • NSC 7887
    • EINECS 219-956-7
    • Guanidine, amino-, hydrogen carbonate
    • BA 51-090222
    • Ba 51-090222 (VAN)
    • AI3-52138
    • N(sup 1)-Aminoguanidine carbonate (1:1)
    • Aminoguanadine bicarbonate
    • Hydrazinecarboximidamide, carbonate (1:1)
    • DTXSID2062537
    • EC 219-956-7
    • NSC-7887
    • X2151435R9
    • RefChem:557548
    • DTXCID9037400
    • AMINOGUANIDINE BICARBONATE [INCI]
    • Carbonic acid, compd. with aminoguanidine (1:1) (8CI)
    • GUANIDINE, AMINO-, BICARBONATE
    • ORISTAR AGBC
    • 2200-97-7
    • 2-aminoguanidine;carbonic acid
    • Aminoguanidine carbonate
    • MFCD00012949
    • Aminoguanidine hydrogencarbonate
    • NSC7887
    • N''-aminoguanidine; carbonic acid
    • amino(diaminomethylidene)azanium;hydrogen carbonate
    • AMINOGUANIDINECARBONATE
    • 2-aminoguanidine,carbonic acid
    • Amino guanidine bicarbonate
    • C2H8N4O3
    • UNII-X2151435R9
    • aminoguandine bicarbonate
    • SCHEMBL40128
    • SCHEMBL7941763
    • 1-aminoguanidine; carbonic acid
    • Aminoguanidine bicarbonate, 97%
    • Amino guanidine hydrogen carbonate
    • 1-aminoguanidine carbonic acid salt
    • HB0111
    • AKOS015894487
    • AKOS015901290
    • hydrazinecarboximidamide bicarbonate salt
    • hydrazinecarboximidamide carbonic acid salt
    • LS-12944
    • A0307
    • ST51037496
    • Carbonic acid--hydrazinecarboximidamide (1/1)
    • F87308
    • Q27293343
    • [amino(hydrazinyl)methylidene]azanium hydrogen carbonate
    • F0001-0859
    • Carbonic acid compound with hydrazinecarboximidamide (1:1)
    • 2582-30-1

  • Applications

    Aminoguanidine bicarbonate (CAS 2582-30-1) is primarily used as a laboratory reagent in biochemical and pharmaceutical research. It serves as a soluble salt form that facilitates in vitro studies, and is commonly employed as an inhibitor of inducible nitric oxide synthase (iNOS) and as a carbonyl scavenger to modulate and study advanced glycation end-product (AGE) formation. It also functions as a synthetic intermediate for constructing guanidine-containing compounds in organic synthesis, enabling preparation of related APIs and research chemicals. In formulation and process development, its bicarbonate salt improves aqueous handling of aminoguanidine for laboratory assays, with usage governed by local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 10.79
    methanol 41.3
    isopropanol 3.7
    water 391.92
    ethyl acetate 0.82
    n-propanol 5.33
    acetone 1.73
    n-butanol 3.42
    acetonitrile 1.76
    DMF 40.12
    toluene 0.39
    isobutanol 2.99
    1,4-dioxane 2.34
    methyl acetate 1.53
    THF 5.32
    2-butanone 1.35
    n-pentanol 1.65
    sec-butanol 2.55
    n-hexane 0.3
    ethylene glycol 24.37
    NMP 38.73
    cyclohexane 0.26
    DMSO 21.91
    n-butyl acetate 0.59
    n-octanol 0.54
    chloroform 1.46
    n-propyl acetate 0.52
    acetic acid 24.63
    dichloromethane 1.55
    cyclohexanone 2.22
    propylene glycol 17.93
    isopropyl acetate 0.49
    DMAc 23.9
    2-ethoxyethanol 6.83
    isopentanol 1.87
    n-heptane 0.26
    ethyl formate 4.94
    1,2-dichloroethane 0.86
    n-hexanol 1.24
    2-methoxyethanol 22.32
    isobutyl acetate 0.25
    tetrachloromethane 0.99
    n-pentyl acetate 0.69
    transcutol 3.92
    n-heptanol 1.25
    ethylbenzene 0.17
    MIBK 0.49
    2-propoxyethanol 5.22
    tert-butanol 2.42
    MTBE 0.78
    2-butoxyethanol 5.18
    propionic acid 8.15
    o-xylene 0.43
    formic acid 138.02
    diethyl ether 0.8
    m-xylene 0.29
    p-xylene 0.28
    chlorobenzene 0.35
    dimethyl carbonate 1.93
    n-octane 0.12
    formamide 75.09
    cyclopentanone 4.64
    2-pentanone 0.98
    anisole 0.41
    cyclopentyl methyl ether 1.8
    gamma-butyrolactone 8.42
    1-methoxy-2-propanol 9.05
    pyridine 2.5
    3-pentanone 0.82
    furfural 13.49
    n-dodecane 0.05
    diethylene glycol 9.18
    diisopropyl ether 0.2
    tert-amyl alcohol 2.33
    acetylacetone 1.0
    n-hexadecane 0.05
    acetophenone 0.62
    methyl propionate 1.6
    isopentyl acetate 0.47
    trichloroethylene 1.43
    n-nonanol 0.52
    cyclohexanol 1.79
    benzyl alcohol 1.11
    2-ethylhexanol 0.58
    isooctanol 0.76
    dipropyl ether 0.62
    1,2-dichlorobenzene 0.34
    ethyl lactate 1.47
    propylene carbonate 4.15
    n-methylformamide 32.82
    2-pentanol 1.29
    n-pentane 0.3
    1-propoxy-2-propanol 2.85
    1-methoxy-2-propyl acetate 0.91
    2-(2-methoxypropoxy) propanol 1.94
    mesitylene 0.19
    ε-caprolactone 2.84
    p-cymene 0.22
    epichlorohydrin 3.73
    1,1,1-trichloroethane 0.49
    2-aminoethanol 27.53
    morpholine-4-carbaldehyde 16.89
    sulfolane 17.16
    2,2,4-trimethylpentane 0.12
    2-methyltetrahydrofuran 2.66
    n-hexyl acetate 0.53
    isooctane 0.05
    2-(2-butoxyethoxy)ethanol 2.79
    sec-butyl acetate 0.26
    tert-butyl acetate 0.43
    decalin 0.08
    glycerin 42.9
    diglyme 5.11
    acrylic acid 12.65
    isopropyl myristate 0.17
    n-butyric acid 6.08
    acetyl acetate 0.59
    di(2-ethylhexyl) phthalate 0.57
    ethyl propionate 0.53
    nitromethane 15.76
    1,2-diethoxyethane 0.63
    benzonitrile 0.82
    trioctyl phosphate 0.45
    1-bromopropane 0.54
    gamma-valerolactone 10.65
    n-decanol 0.36
    triethyl phosphate 0.53
    4-methyl-2-pentanol 0.57
    propionitrile 1.35
    vinylene carbonate 4.16
    1,1,2-trichlorotrifluoroethane 12.27
    DMS 0.62
    cumene 0.16
    2-octanol 0.52
    2-hexanone 0.5
    octyl acetate 0.32
    limonene 0.3
    1,2-dimethoxyethane 4.95
    ethyl orthosilicate 0.55
    tributyl phosphate 0.45
    diacetone alcohol 1.75
    N,N-dimethylaniline 0.66
    acrylonitrile 2.65
    aniline 1.5
    1,3-propanediol 15.99
    bromobenzene 0.23
    dibromomethane 0.92
    1,1,2,2-tetrachloroethane 1.36
    2-methyl-cyclohexyl acetate 0.42
    tetrabutyl urea 0.84
    diisobutyl methanol 0.3
    2-phenylethanol 0.85
    styrene 0.19
    dioctyl adipate 0.3
    dimethyl sulfate 5.13
    ethyl butyrate 0.51
    methyl lactate 5.62
    butyl lactate 1.79
    diethyl carbonate 0.38
    propanediol butyl ether 4.54
    triethyl orthoformate 0.65
    p-tert-butyltoluene 0.22
    methyl 4-tert-butylbenzoate 1.32
    morpholine 5.38
    tert-butylamine 1.22
    n-dodecanol 0.25
    dimethoxymethane 6.25
    ethylene carbonate 2.8
    cyrene 3.38
    2-ethoxyethyl acetate 0.95
    2-ethylhexyl acetate 0.38
    1,2,4-trichlorobenzene 0.44
    4-methylpyridine 2.17
    dibutyl ether 0.29
    2,6-dimethyl-4-heptanol 0.3
    DEF 4.26
    dimethyl isosorbide 2.42
    tetrachloroethylene 1.77
    eugenol 2.14
    triacetin 0.71
    span 80 2.05
    1,4-butanediol 5.65
    1,1-dichloroethane 0.58
    2-methyl-1-pentanol 1.07
    methyl formate 19.2
    2-methyl-1-butanol 2.41
    n-decane 0.09
    butyronitrile 1.39
    3,7-dimethyl-1-octanol 0.36
    1-chlorooctane 0.15
    1-chlorotetradecane 0.06
    n-nonane 0.09
    undecane 0.06
    tert-butylcyclohexane 0.07
    cyclooctane 0.12
    cyclopentanol 4.03
    tetrahydropyran 1.41
    tert-amyl methyl ether 0.84
    2,5,8-trioxanonane 3.08
    1-hexene 0.46
    2-isopropoxyethanol 2.35
    2,2,2-trifluoroethanol 16.2
    methyl butyrate 1.04

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction