alpha-Amylase from Aspergillus oryzae

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  • Identifiers

    CAS number
    9001-19-8

    Molecular formula
    C20H16ClF5N4O3

    SMILES
    CN1C(=C(C(=C1Cl)C(=O)C(=O)NC2(CCC2)C(F)(F)F)F)C(NC3=CC(=C(C=C3)F)C#N)O

    Safety labels

    Health Hazard
    Health

  • Odor profile

    Fragrance
    Odorless 70.2%
    Savory 26.06%
    Cooling 25.29%
    Bitter 20.56%
    Milky 20.32%
    Animal 18.77%
    Sweet 17.33%
    Cooked 16.4%
    Meaty 16.0%
    Musk 14.68%

     

    Flavor
    Bitter 85.21%
    Odorless 46.78%
    Bland 28.3%
    Sweet-like 20.29%
    Mild 19.22%
    Nitrile 18.77%
    Cedarleaf 17.97%
    Very strong 17.72%
    Indole 17.49%
    Scallion 17.34%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    3.5

    pKa est.
    3.96 (weak acid)

    Molecular weight
    490.8 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    1102°C

    Flash point

    • 179.03 ˚C est.

  • Synonyms

    • alpha-Amylase from Aspergillus oryzae
    • 9001-19-8
    • SCHEMBL20458738
    • 9001-19-8

  • Applications

    alpha-Amylase from Aspergillus oryzae (CAS 9001-19-8) is an enzyme widely used as a processing aid to hydrolyze starch into fermentable sugars such as glucose and maltose, supporting starch liquefaction and saccharification in food and beverage production; in brewing and distilling it aids starch breakdown during mashing; in baking it improves dough handling and crumb structure; in textile processing it is used for desizing by removing starch-based sizes from fabrics; in cleaning and household formulations it functions in enzyme-containing detergents to enhance removal of starch soils; and in animal feed and fermentation applications it enhances starch digestibility and nutritional availability; subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 13.44
    methanol 29.42
    isopropanol 7.5
    water 0.09
    ethyl acetate 15.88
    n-propanol 9.38
    acetone 53.28
    n-butanol 5.93
    acetonitrile 16.96
    DMF 106.54
    toluene 3.26
    isobutanol 5.02
    1,4-dioxane 33.06
    methyl acetate 28.48
    THF 74.01
    2-butanone 31.65
    n-pentanol 6.34
    sec-butanol 6.56
    n-hexane 0.14
    ethylene glycol 9.62
    NMP 101.62
    cyclohexane 0.21
    DMSO 118.5
    n-butyl acetate 9.48
    n-octanol 5.41
    chloroform 17.15
    n-propyl acetate 13.89
    acetic acid 51.85
    dichloromethane 21.63
    cyclohexanone 38.45
    propylene glycol 9.31
    isopropyl acetate 9.9
    DMAc 124.08
    2-ethoxyethanol 35.45
    isopentanol 4.65
    n-heptane 0.24
    ethyl formate 16.99
    1,2-dichloroethane 11.56
    n-hexanol 4.83
    2-methoxyethanol 53.54
    isobutyl acetate 5.72
    tetrachloromethane 1.74
    n-pentyl acetate 13.05
    transcutol 49.98
    n-heptanol 5.4
    ethylbenzene 1.7
    MIBK 8.82
    2-propoxyethanol 32.09
    tert-butanol 6.79
    MTBE 6.1
    2-butoxyethanol 23.19
    propionic acid 18.42
    o-xylene 2.18
    formic acid 46.0
    diethyl ether 6.94
    m-xylene 1.59
    p-xylene 2.5
    chlorobenzene 3.59
    dimethyl carbonate 21.47
    n-octane 0.16
    formamide 66.59
    cyclopentanone 61.97
    2-pentanone 17.14
    anisole 9.77
    cyclopentyl methyl ether 10.39
    gamma-butyrolactone 69.81
    1-methoxy-2-propanol 30.21
    pyridine 28.86
    3-pentanone 14.16
    furfural 61.78
    n-dodecane 0.19
    diethylene glycol 30.71
    diisopropyl ether 1.52
    tert-amyl alcohol 6.64
    acetylacetone 40.56
    n-hexadecane 0.22
    acetophenone 15.82
    methyl propionate 20.16
    isopentyl acetate 6.93
    trichloroethylene 30.21
    n-nonanol 5.62
    cyclohexanol 4.96
    benzyl alcohol 11.45
    2-ethylhexanol 2.77
    isooctanol 3.92
    dipropyl ether 4.96
    1,2-dichlorobenzene 3.66
    ethyl lactate 13.02
    propylene carbonate 23.4
    n-methylformamide 49.75
    2-pentanol 3.54
    n-pentane 0.16
    1-propoxy-2-propanol 17.28
    1-methoxy-2-propyl acetate 16.78
    2-(2-methoxypropoxy) propanol 22.45
    mesitylene 0.82
    ε-caprolactone 30.94
    p-cymene 1.49
    epichlorohydrin 55.58
    1,1,1-trichloroethane 7.6
    2-aminoethanol 13.68
    morpholine-4-carbaldehyde 87.83
    sulfolane 95.25
    2,2,4-trimethylpentane 0.12
    2-methyltetrahydrofuran 21.92
    n-hexyl acetate 13.56
    isooctane 0.06
    2-(2-butoxyethoxy)ethanol 28.2
    sec-butyl acetate 7.11
    tert-butyl acetate 10.09
    decalin 0.13
    glycerin 20.27
    diglyme 55.7
    acrylic acid 26.43
    isopropyl myristate 4.85
    n-butyric acid 14.5
    acetyl acetate 16.35
    di(2-ethylhexyl) phthalate 7.69
    ethyl propionate 11.24
    nitromethane 117.97
    1,2-diethoxyethane 14.98
    benzonitrile 9.88
    trioctyl phosphate 5.02
    1-bromopropane 4.49
    gamma-valerolactone 104.33
    n-decanol 4.08
    triethyl phosphate 5.17
    4-methyl-2-pentanol 2.09
    propionitrile 10.69
    vinylene carbonate 25.22
    1,1,2-trichlorotrifluoroethane 57.66
    DMS 16.16
    cumene 1.09
    2-octanol 3.93
    2-hexanone 16.49
    octyl acetate 7.87
    limonene 2.09
    1,2-dimethoxyethane 49.88
    ethyl orthosilicate 4.58
    tributyl phosphate 4.92
    diacetone alcohol 17.63
    N,N-dimethylaniline 6.1
    acrylonitrile 20.3
    aniline 7.29
    1,3-propanediol 15.39
    bromobenzene 2.96
    dibromomethane 10.66
    1,1,2,2-tetrachloroethane 19.47
    2-methyl-cyclohexyl acetate 7.42
    tetrabutyl urea 11.02
    diisobutyl methanol 1.67
    2-phenylethanol 10.7
    styrene 2.42
    dioctyl adipate 9.66
    dimethyl sulfate 39.21
    ethyl butyrate 8.21
    methyl lactate 23.29
    butyl lactate 13.42
    diethyl carbonate 6.14
    propanediol butyl ether 21.04
    triethyl orthoformate 7.02
    p-tert-butyltoluene 1.35
    methyl 4-tert-butylbenzoate 16.68
    morpholine 37.53
    tert-butylamine 2.47
    n-dodecanol 2.77
    dimethoxymethane 55.59
    ethylene carbonate 17.63
    cyrene 33.65
    2-ethoxyethyl acetate 24.39
    2-ethylhexyl acetate 5.16
    1,2,4-trichlorobenzene 6.09
    4-methylpyridine 19.44
    dibutyl ether 4.46
    2,6-dimethyl-4-heptanol 1.67
    DEF 25.0
    dimethyl isosorbide 35.54
    tetrachloroethylene 12.07
    eugenol 20.04
    triacetin 22.95
    span 80 17.54
    1,4-butanediol 8.46
    1,1-dichloroethane 8.59
    2-methyl-1-pentanol 4.79
    methyl formate 47.5
    2-methyl-1-butanol 4.66
    n-decane 0.32
    butyronitrile 7.76
    3,7-dimethyl-1-octanol 3.5
    1-chlorooctane 1.9
    1-chlorotetradecane 0.78
    n-nonane 0.25
    undecane 0.24
    tert-butylcyclohexane 0.12
    cyclooctane 0.08
    cyclopentanol 9.08
    tetrahydropyran 13.42
    tert-amyl methyl ether 5.49
    2,5,8-trioxanonane 42.52
    1-hexene 1.0
    2-isopropoxyethanol 20.19
    2,2,2-trifluoroethanol 23.32
    methyl butyrate 15.27

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction