Alanylglutamine

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  • Identifiers

    CAS number
    39537-23-0

    Molecular formula
    C8H15N3O4

    SMILES
    C[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)O)N

  • Odor profile

    Fragrance
    Odorless 67.35%
    Savory 42.49%
    Sweet 31.6%
    Meaty 28.57%
    Fishy 25.66%
    Cooling 20.74%
    Cooked 19.25%
    Milky 18.2%
    Cocoa 16.65%
    Alcoholic 15.26%

     

    Flavor
    Odorless 63.27%
    Bitter 37.87%
    Mild 30.34%
    Bland 30.31%
    Very mild 24.75%
    Yeast 22.48%
    Sweet-like 22.31%
    Cooked 21.04%
    Faint 20.95%
    Nitrile 19.68%

     

    Odor impact est.
    Odorless

  • Properties

    XLogP3-AA
    -4.4

    pKa est.
    5.67 (weak acid)

    Molecular weight
    217.22 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    394°C

    Melting point expt.

    • 230.00 to 232.00 °C. @ 760.00 mm Hg

    Flash point

    • 235.87 ˚C est.

    Solubility expt.

    • Soluble in water
    • Very slightly soluble (in ethanol)

  • Synonyms

    • l-Alanyl-l-glutamine
    • 39537-23-0
    • Ala-gln
    • alanylglutamine
    • Alanyl-glutamine
    • alanyl glutamine
    • Dipeptamin
    • GlutaMAX
    • Sustamine
    • L-Glutamine, L-alanyl-
    • N(2)-L-Alanyl-L-glutamine
    • Dipeptiven
    • L-Ala-L-Gln
    • Glutamax I
    • H-Ala-Gln-OH
    • Alanyl-glutamine dipeptide
    • Dipeptide Alanyl-Glutamine
    • L-Glutamine, N2-L-alanyl-
    • U5JDO2770Z
    • L-alanyl-l-glutamine amino acid
    • FEMA NO. 4712
    • N(2)-L-Alanine L-Glutamine dipeptide
    • CHEBI:73788
    • GLUTAMINE, N2-L-ALANYL-
    • DTXSID20192658
    • ALANYL GLUTAMINE [WHO-DD]
    • (2S)-5-amino-2-[[(2S)-2-aminopropanoyl]amino]-5-oxopentanoic acid
    • L-ALANYL-L-GLUTAMINE [USP-RS]
    • (S)-5-amino-2-((S)-2-aminopropanamido)-5-oxopentanoic acid
    • (2S)-5-Amino-2-(((2S)-2-aminopropanoyl)amino)-5-oxopentanoic acid
    • (2S)-5-amino-2-{[(2S)-2-aminopropanoyl]amino}-5-oxopentanoic acid
    • MFCD00133046
    • L-ALANYL-L-GLUTAMINE (USP-RS)
    • L-Alany-L-glutamine
    • UNII-U5JDO2770Z
    • AlaGln
    • AQ dipeptide
    • LAlanylLglutamine
    • L-Alanyl-L-glutamine 1-hydrate
    • A-Q Dipeptide
    • LGlutamine, Lalanyl
    • (2S)-5-amino-2-{[(2S)-2-azaniumylpropanoyl]amino}-5-oxopentanoate
    • L-alanyl/L-glutamine
    • LGlutamine, N2Lalanyl
    • N(2)LAlanylLglutamine
    • Alanine Glutamine dipeptide
    • Alanine-Glutamine dipeptide
    • 210541-56-3
    • L-Ala-Gln, for cell culture
    • SCHEMBL133887
    • ALANYL GLUTAMINE [INCI]
    • CHEMBL3707366
    • DTXCID60115149
    • L-Alanyl-L-glutamine (Standard)
    • Ala-Gln, >=98% (TLC)
    • BDBM627986
    • HY-W014102R
    • N(2)-L-ALANYL-LEVOGLUTAMIDE
    • s5801
    • AKOS010366801
    • (2S)5Amino2(amino)5oxopentanoic acid
    • CS-W014818
    • DB11876
    • FA29476
    • HY-W014102
    • CVD-0019434
    • L-Alanyl-L-glutamine, for cell culture
    • AS-12601
    • DB-030066
    • A1261
    • NS00006426
    • BRD-K11595419-001-01-4
    • Q27144111
    • (S)-5-amino-2-((S)-2-aminopropanamido)-5-oxopentanoicacid
    • L-Alanyl-L-glutamine, United States Pharmacopeia (USP) Reference Standard
    • Ala-Gln, BioReagent, suitable for cell culture, suitable for insect cell culture
    • 475-290-9
    • 609-717-9

  • Applications

    Alanylglutamine, CAS 39537-23-0, is a dipeptide of alanine and glutamine primarily used as a stable glutamine source in medical nutrition (parenteral and enteral) to support patient care; it is also employed in sports nutrition products and dietary supplements to deliver glutamine in a stable form. In biotech and biopharmaceutical manufacturing, it is commonly used as a stable nitrogen source in cell culture media and fermentation processes. It is also considered as a component in pharmaceutical and nutraceutical formulations and may appear in industrial manufacturing applications requiring a stable amino acid supply, subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.22
    methanol 0.53
    isopropanol 0.14
    water 57.59
    ethyl acetate 0.12
    n-propanol 0.14
    acetone 0.19
    n-butanol 0.15
    acetonitrile 0.16
    DMF 13.17
    toluene 0.09
    isobutanol 0.13
    1,4-dioxane 0.89
    methyl acetate 0.12
    THF 0.7
    2-butanone 0.16
    n-pentanol 0.14
    sec-butanol 0.15
    n-hexane 0.15
    ethylene glycol 3.33
    NMP 29.41
    cyclohexane 0.13
    DMSO 23.91
    n-butyl acetate 0.14
    n-octanol 0.09
    chloroform 0.05
    n-propyl acetate 0.11
    acetic acid 3.62
    dichloromethane 0.1
    cyclohexanone 0.96
    propylene glycol 1.97
    isopropyl acetate 0.11
    DMAc 13.71
    2-ethoxyethanol 1.55
    isopentanol 0.17
    n-heptane 0.11
    ethyl formate 0.39
    1,2-dichloroethane 0.09
    n-hexanol 0.18
    2-methoxyethanol 3.54
    isobutyl acetate 0.07
    tetrachloromethane 0.04
    n-pentyl acetate 0.11
    transcutol 2.27
    n-heptanol 0.14
    ethylbenzene 0.11
    MIBK 0.14
    2-propoxyethanol 1.34
    tert-butanol 0.26
    MTBE 0.11
    2-butoxyethanol 0.77
    propionic acid 0.6
    o-xylene 0.2
    formic acid 30.25
    diethyl ether 0.12
    m-xylene 0.1
    p-xylene 0.2
    chlorobenzene 0.05
    dimethyl carbonate 0.45
    n-octane 0.05
    formamide 13.99
    cyclopentanone 1.05
    2-pentanone 0.16
    anisole 0.18
    cyclopentyl methyl ether 0.45
    gamma-butyrolactone 1.77
    1-methoxy-2-propanol 1.77
    pyridine 0.5
    3-pentanone 0.22
    furfural 4.84
    n-dodecane 0.02
    diethylene glycol 4.93
    diisopropyl ether 0.06
    tert-amyl alcohol 0.28
    acetylacetone 0.51
    n-hexadecane 0.02
    acetophenone 0.38
    methyl propionate 0.25
    isopentyl acetate 0.14
    trichloroethylene 0.11
    n-nonanol 0.09
    cyclohexanol 0.43
    benzyl alcohol 0.34
    2-ethylhexanol 0.14
    isooctanol 0.12
    dipropyl ether 0.24
    1,2-dichlorobenzene 0.08
    ethyl lactate 0.5
    propylene carbonate 1.11
    n-methylformamide 3.05
    2-pentanol 0.12
    n-pentane 0.06
    1-propoxy-2-propanol 0.78
    1-methoxy-2-propyl acetate 0.48
    2-(2-methoxypropoxy) propanol 1.2
    mesitylene 0.1
    ε-caprolactone 1.17
    p-cymene 0.1
    epichlorohydrin 0.51
    1,1,1-trichloroethane 0.03
    2-aminoethanol 2.01
    morpholine-4-carbaldehyde 16.55
    sulfolane 10.73
    2,2,4-trimethylpentane 0.03
    2-methyltetrahydrofuran 0.38
    n-hexyl acetate 0.11
    isooctane 0.01
    2-(2-butoxyethoxy)ethanol 1.29
    sec-butyl acetate 0.08
    tert-butyl acetate 0.16
    decalin 0.07
    glycerin 14.52
    diglyme 2.64
    acrylic acid 1.49
    isopropyl myristate 0.06
    n-butyric acid 0.61
    acetyl acetate 0.2
    di(2-ethylhexyl) phthalate 0.19
    ethyl propionate 0.17
    nitromethane 2.59
    1,2-diethoxyethane 0.26
    benzonitrile 0.2
    trioctyl phosphate 0.12
    1-bromopropane 0.05
    gamma-valerolactone 5.4
    n-decanol 0.08
    triethyl phosphate 0.3
    4-methyl-2-pentanol 0.1
    propionitrile 0.1
    vinylene carbonate 1.04
    1,1,2-trichlorotrifluoroethane 3.25
    DMS 0.32
    cumene 0.11
    2-octanol 0.09
    2-hexanone 0.14
    octyl acetate 0.08
    limonene 0.12
    1,2-dimethoxyethane 1.96
    ethyl orthosilicate 0.28
    tributyl phosphate 0.15
    diacetone alcohol 0.82
    N,N-dimethylaniline 0.42
    acrylonitrile 0.23
    aniline 0.22
    1,3-propanediol 1.56
    bromobenzene 0.04
    dibromomethane 0.06
    1,1,2,2-tetrachloroethane 0.14
    2-methyl-cyclohexyl acetate 0.21
    tetrabutyl urea 0.37
    diisobutyl methanol 0.12
    2-phenylethanol 0.25
    styrene 0.09
    dioctyl adipate 0.12
    dimethyl sulfate 2.45
    ethyl butyrate 0.19
    methyl lactate 1.61
    butyl lactate 0.41
    diethyl carbonate 0.15
    propanediol butyl ether 1.12
    triethyl orthoformate 0.3
    p-tert-butyltoluene 0.09
    methyl 4-tert-butylbenzoate 0.54
    morpholine 1.18
    tert-butylamine 0.13
    n-dodecanol 0.07
    dimethoxymethane 1.39
    ethylene carbonate 0.69
    cyrene 4.22
    2-ethoxyethyl acetate 0.23
    2-ethylhexyl acetate 0.13
    1,2,4-trichlorobenzene 0.11
    4-methylpyridine 0.4
    dibutyl ether 0.1
    2,6-dimethyl-4-heptanol 0.12
    DEF 1.4
    dimethyl isosorbide 2.47
    tetrachloroethylene 0.18
    eugenol 0.85
    triacetin 0.36
    span 80 0.93
    1,4-butanediol 0.84
    1,1-dichloroethane 0.03
    2-methyl-1-pentanol 0.16
    methyl formate 1.95
    2-methyl-1-butanol 0.18
    n-decane 0.03
    butyronitrile 0.11
    3,7-dimethyl-1-octanol 0.07
    1-chlorooctane 0.04
    1-chlorotetradecane 0.02
    n-nonane 0.04
    undecane 0.02
    tert-butylcyclohexane 0.04
    cyclooctane 0.07
    cyclopentanol 0.47
    tetrahydropyran 0.28
    tert-amyl methyl ether 0.17
    2,5,8-trioxanonane 2.47
    1-hexene 0.14
    2-isopropoxyethanol 0.67
    2,2,2-trifluoroethanol 3.06
    methyl butyrate 0.28

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction