Alanine

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  • Identifiers

    CAS number
    56-41-7

    Molecular formula
    C3H7NO2

    SMILES
    C[C@@H](C(=O)O)N

  • Odor profile

    Fragrance
    Odorless 81.5%
    Savory 24.78%
    Meaty 19.79%
    Cheesy 17.94%
    Milky 17.21%
    Fishy 16.32%
    Sour 15.93%
    Sweet 15.86%
    Buttery 15.77%
    Sulfurous 15.61%

     

    Flavor
    Odorless 68.92%
    Sour 30.81%
    Acidic 28.34%
    Mild 28.29%
    Bland 24.33%
    Yeast 23.15%
    Sulfury 21.25%
    Soy 21.18%
    Mousy 20.84%
    Roquefort cheese 20.54%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -3.0

    pKa est.
    5.97 (weak acid)

    Molecular weight
    89.09 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderately slow

    Melting point expt.

    • 300 dec °C
    • 297 °C (decomposes)
    • 300 °C

    Boiling point

    • 250 °C (sublimes)

    Flash point

    • 104.44 ˚C est.

    Solubility expt.

    • 164000 mg/L (at 25 °C)
    • Solubility in cold 80% ethanol = 0.2%
    • Slightly soluble in ethanol, pyridine; insoluble in ether, acetone
    • In water, 1.64X10+5 mg/L at 25 °C
    • 204 mg/mL

  • Synonyms

    • L-alanine
    • 56-41-7
    • alanine
    • H-Ala-OH
    • (S)-Alanine
    • L-alpha-alanine
    • (2S)-2-Aminopropanoic acid
    • (S)-2-Aminopropanoic acid
    • L-2-Aminopropionic acid
    • 2-Aminopropionic acid
    • L-(+)-Alanine
    • L-2-Aminopropanoic acid
    • alpha-Alanine
    • (L)-Alanine
    • L-alpha-Aminopropionic acid
    • alpha-Aminopropionic acid
    • L-2-Aminopropionsaeure
    • (S)-(+)-Alanine
    • L-S-Aminopropionic acid
    • (S)-2-Aminopropionsaeure
    • 2-Aminopropanoic acid, L-
    • Alaninum [Latin]
    • (S)-alpha-Aminopropionsaeure
    • Alaninum
    • Alanine (VAN)
    • ALANINE, L-
    • L-Alanin
    • Alanine [USAN:INN]
    • Alanina [DCIT,Spanish]
    • (S)-2-Aminopropionic acid
    • Propanoic acid, 2-amino-, (S)-
    • L-a-Aminopropionic acid
    • HSDB 1801
    • NSC 206315
    • 25191-17-7
    • UNII-OF5P57N2ZX
    • EINECS 200-273-8
    • OF5P57N2ZX
    • MFCD00064410
    • L-Ala
    • CHEBI:16977
    • l alanine
    • CHEMBL279597
    • L-Isomer alanine
    • DTXSID20873899
    • EC 200-273-8
    • Alaninum (Latin)
    • Alanine, L isomer
    • Alanine, L-isomer
    • 6898-94-8
    • ALANINE (II)
    • ALANINE [II]
    • a-Alanine
    • L-a-Alanine
    • 115967-49-2
    • ALANINE (EP MONOGRAPH)
    • ALANINE [EP MONOGRAPH]
    • 14C-L-Alanine
    • a-Aminopropionic acid
    • ALANINE (USP MONOGRAPH)
    • ALANINE [USP MONOGRAPH]
    • (C14)L-Alanine
    • .alpha.-Alanine
    • L-.alpha.-Alanine
    • NSC-206315
    • L-&alpha-alanine
    • SERINE IMPURITY A (EP IMPURITY)
    • SERINE IMPURITY A [EP IMPURITY]
    • VALINE IMPURITY A (EP IMPURITY)
    • VALINE IMPURITY A [EP IMPURITY]
    • Alanine (USP)
    • L-Alanine (9CI)
    • 2-Ammoniopropanoate
    • .alpha.-Aminopropionic acid
    • LYSINE ACETATE IMPURITY C (EP IMPURITY)
    • LYSINE ACETATE IMPURITY C [EP IMPURITY]
    • L-Alanine, labeled with carbon-14
    • L-.alpha.-Aminopropionic acid
    • Ritalanine
    • Racemic alanine
    • L-aAlanine
    • a-Aminopropionate
    • L-Alanine, labeled with tritium
    • 3h-l-alanine
    • L-Alanine Powder
    • Propanoic acid, 2-amino-, (S)
    • [3H]alanine
    • L-a-Aminopropionate
    • [14C]alanine
    • [3H]-alanine
    • alpha-Aminopropanoate
    • alpha-Aminopropionate
    • L-2-Aminopropanoate
    • L-2-Aminopropionate
    • [14C]-alanine
    • Alanine (L-Alanine)
    • L-Alanine (Standard)
    • L-alpha-Aminopropionate
    • Tocris-0205
    • 2-Ammoniopropanoic acid
    • ALA-OH
    • starbld0003382
    • L-Alanine (JP18)
    • (S)-2-Aminopropanoate
    • ALANINE [VANDF]
    • ALANINE [HSDB]
    • ALANINE [USAN]
    • ALANINE [INN]
    • alpha-Aminopropanoic acid
    • ALANINE [MI]
    • L-Ala-2
    • L-ALANINE [FCC]
    • L-ALANINE [JAN]
    • (S)-2-amino-Propanoate
    • ALANINE [WHO-DD]
    • L-Alanine, >=99%
    • bmse000028
    • bmse000994
    • L-CH3CH(NH2)COOH
    • L-ALANINE [USP-RS]
    • GTPL720
    • (S)-2-amino-Propanoic acid
    • 26336-61-8
    • Alanine, L- (7CI,8CI)
    • GTPL4542
    • GTPL4543
    • HY-N0229R
    • L-Alanine, >=98% (TLC)

  • Applications

    L-Alanine (CAS 56-41-7) is a non-essential yet highly versatile amino acid whose applications span food, pharmaceutical and scientific fields: in sports drinks and energy beverages it supplies fast fuel and imparts a mild sweetness; in food technology it serves as a flavour enhancer, meat-like aroma precursor and nutritional fortifier for confectionery, soups and seasonings; in medicine it is incorporated into parenteral nutrition solutions, electrolyte replenishment fluids, and amino acid supplements for postoperative or cachectic patients, while also acting as a hepatoprotective agent and substrate for liver function assays; in animal nutrition it is added to balance amino acid profiles, promote weight gain and improve feed conversion in livestock, poultry and aquaculture; in biotechnology it functions as a buffering component, carbon-nitrogen source in microbial media, internal standard in chromatography and NMR, peptide synthesis building block, and metabolic tracer in physiological and pharmacokinetic studies; additionally, L-Alanine is used in the production of biodegradable polymers, chelating agents and biosensors, broadening the portfolio of eco-friendly materials and supporting life-science research.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 0.4
    methanol 1.07
    isopropanol 0.22
    water 155.79
    ethyl acetate 0.13
    n-propanol 0.29
    acetone 0.17
    n-butanol 0.41
    acetonitrile 0.22
    DMF 1.33
    toluene 0.07
    isobutanol 0.3
    1,4-dioxane 0.34
    methyl acetate 0.1
    THF 0.35
    2-butanone 0.17
    n-pentanol 0.23
    sec-butanol 0.34
    n-hexane 0.09
    ethylene glycol 4.15
    NMP 6.03
    cyclohexane 0.11
    DMSO 3.38
    n-butyl acetate 0.1
    n-octanol 0.15
    chloroform 0.1
    n-propyl acetate 0.07
    acetic acid 4.78
    dichloromethane 0.12
    cyclohexanone 0.52
    propylene glycol 2.04
    isopropyl acetate 0.13
    DMAc 2.15
    2-ethoxyethanol 0.84
    isopentanol 0.41
    n-heptane 0.11
    ethyl formate 0.36
    1,2-dichloroethane 0.09
    n-hexanol 0.23
    2-methoxyethanol 1.67
    isobutyl acetate 0.05
    tetrachloromethane 0.13
    n-pentyl acetate 0.16
    transcutol 1.88
    n-heptanol 0.28
    ethylbenzene 0.08
    MIBK 0.19
    2-propoxyethanol 0.74
    tert-butanol 0.43
    MTBE 0.16
    2-butoxyethanol 0.97
    propionic acid 0.78
    o-xylene 0.17
    formic acid 25.86
    diethyl ether 0.1
    m-xylene 0.11
    p-xylene 0.13
    chlorobenzene 0.05
    dimethyl carbonate 0.19
    n-octane 0.06
    formamide 9.35
    cyclopentanone 0.57
    2-pentanone 0.18
    anisole 0.1
    cyclopentyl methyl ether 0.28
    gamma-butyrolactone 0.77
    1-methoxy-2-propanol 0.92
    pyridine 0.23
    3-pentanone 0.18
    furfural 1.86
    n-dodecane 0.02
    diethylene glycol 2.7
    diisopropyl ether 0.08
    tert-amyl alcohol 0.62
    acetylacetone 0.34
    n-hexadecane 0.03
    acetophenone 0.22
    methyl propionate 0.16
    isopentyl acetate 0.15
    trichloroethylene 0.15
    n-nonanol 0.15
    cyclohexanol 0.49
    benzyl alcohol 0.26
    2-ethylhexanol 0.21
    isooctanol 0.26
    dipropyl ether 0.12
    1,2-dichlorobenzene 0.09
    ethyl lactate 0.3
    propylene carbonate 0.58
    n-methylformamide 1.04
    2-pentanol 0.26
    n-pentane 0.07
    1-propoxy-2-propanol 0.52
    1-methoxy-2-propyl acetate 0.28
    2-(2-methoxypropoxy) propanol 1.37
    mesitylene 0.13
    ε-caprolactone 0.58
    p-cymene 0.13
    epichlorohydrin 0.29
    1,1,1-trichloroethane 0.07
    2-aminoethanol 2.39
    morpholine-4-carbaldehyde 2.9
    sulfolane 3.62
    2,2,4-trimethylpentane 0.08
    2-methyltetrahydrofuran 0.31
    n-hexyl acetate 0.16
    isooctane 0.05
    2-(2-butoxyethoxy)ethanol 1.46
    sec-butyl acetate 0.07
    tert-butyl acetate 0.21
    decalin 0.07
    glycerin 9.01
    diglyme 1.69
    acrylic acid 1.5
    isopropyl myristate 0.08
    n-butyric acid 0.81
    acetyl acetate 0.21
    di(2-ethylhexyl) phthalate 0.38
    ethyl propionate 0.09
    nitromethane 1.64
    1,2-diethoxyethane 0.16
    benzonitrile 0.15
    trioctyl phosphate 0.23
    1-bromopropane 0.06
    gamma-valerolactone 1.41
    n-decanol 0.12
    triethyl phosphate 0.22
    4-methyl-2-pentanol 0.22
    propionitrile 0.12
    vinylene carbonate 0.48
    1,1,2-trichlorotrifluoroethane 1.84
    DMS 0.2
    cumene 0.11
    2-octanol 0.17
    2-hexanone 0.11
    octyl acetate 0.12
    limonene 0.16
    1,2-dimethoxyethane 0.55
    ethyl orthosilicate 0.23
    tributyl phosphate 0.23
    diacetone alcohol 0.85
    N,N-dimethylaniline 0.22
    acrylonitrile 0.19
    aniline 0.18
    1,3-propanediol 1.8
    bromobenzene 0.04
    dibromomethane 0.09
    1,1,2,2-tetrachloroethane 0.18
    2-methyl-cyclohexyl acetate 0.2
    tetrabutyl urea 0.4
    diisobutyl methanol 0.21
    2-phenylethanol 0.28
    styrene 0.06
    dioctyl adipate 0.17
    dimethyl sulfate 0.69
    ethyl butyrate 0.13
    methyl lactate 0.74
    butyl lactate 0.49
    diethyl carbonate 0.09
    propanediol butyl ether 1.47
    triethyl orthoformate 0.18
    p-tert-butyltoluene 0.13
    methyl 4-tert-butylbenzoate 0.78
    morpholine 0.41
    tert-butylamine 0.21
    n-dodecanol 0.1
    dimethoxymethane 0.35
    ethylene carbonate 0.32
    cyrene 2.37
    2-ethoxyethyl acetate 0.26
    2-ethylhexyl acetate 0.12
    1,2,4-trichlorobenzene 0.11
    4-methylpyridine 0.2
    dibutyl ether 0.08
    2,6-dimethyl-4-heptanol 0.21
    DEF 0.55
    dimethyl isosorbide 1.75
    tetrachloroethylene 0.29
    eugenol 1.02
    triacetin 0.4
    span 80 1.37
    1,4-butanediol 0.89
    1,1-dichloroethane 0.05
    2-methyl-1-pentanol 0.31
    methyl formate 0.8
    2-methyl-1-butanol 0.46
    n-decane 0.04
    butyronitrile 0.16
    3,7-dimethyl-1-octanol 0.16
    1-chlorooctane 0.05
    1-chlorotetradecane 0.03
    n-nonane 0.04
    undecane 0.03
    tert-butylcyclohexane 0.06
    cyclooctane 0.09
    cyclopentanol 0.55
    tetrahydropyran 0.17
    tert-amyl methyl ether 0.23
    2,5,8-trioxanonane 2.07
    1-hexene 0.09
    2-isopropoxyethanol 0.47
    2,2,2-trifluoroethanol 3.5
    methyl butyrate 0.16

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction