Adonitol

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  • Identifiers

    CAS number
    488-81-3

    Molecular formula
    C5H12O5

    SMILES
    C([C@H](C([C@H](CO)O)O)O)O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Odorless 70.48%
    Sweet 46.65%
    Alcoholic 24.43%
    Caramellic 22.37%
    Buttery 19.02%
    Clean 17.35%
    Fishy 15.78%
    Cooling 15.13%
    Bitter 15.13%
    Oily 15.02%

     

    Flavor
    Odorless 75.07%
    Sweet 62.35%
    Sweet-like 34.29%
    Very mild 24.16%
    Very slight 23.03%
    Mild 19.93%
    Bland 19.8%
    Cauliflower 19.75%
    Yeast 19.36%
    Soup 19.11%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    -2.5

    pKa est.
    5.58 (weak acid)

    Molecular weight
    152.15 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    537°C

    Flash point

    • 220.64 ˚C est.

  • Synonyms

    • xylitol
    • ribitol
    • adonitol
    • 488-81-3
    • 87-99-0
    • Xylite
    • D-Xylitol
    • Adonit
    • Adonite
    • D-ribitol
    • Xyliton
    • Eutrit
    • Klinit
    • Xylite (sugar)
    • Kannit
    • Xylit
    • Newtol
    • 1,2,3,4,5-pentanepentol
    • meso-ribitol
    • L-ribitol
    • Pentitol
    • (2R,3s,4S)-pentane-1,2,3,4,5-pentol
    • Fluorette
    • Xylisorb
    • Kylit
    • xylo-Pentitol
    • D-Adonitol
    • Xylitab 300
    • (2R,3R,4S)-Pentane-1,2,3,4,5-pentaol
    • meso-xylitol
    • CHEBI:15963
    • L-xylitol
    • Xylitol, d-
    • Xylitol cm 90
    • Ribitol (Adonitol)
    • RIBO-PENTITOL
    • CHEBI:17151
    • (2S,4R)-pentane-1,2,3,4,5-pentol
    • D-ribitol (incorrect)
    • L-ribitol (incorrect)
    • 2,3-DihydroAcrivastine
    • (2R,3r,4S)-pentane-1,2,3,4,5-pentol
    • ADONITOL [MI]
    • xylo-Pentane-1,2,3,4,5-pentol
    • (2R,3S,4S)-Pentane-1,2,3,4,5-pentaol
    • 2,3-Dihydro Acrivastine
    • C-xylidex cr 16055
    • EINECS 207-685-7
    • MFCD00064291
    • MFCD00064292
    • NSC 16868
    • 87849-01-2
    • BRN 1720524
    • 353ZQ9TVDA
    • VCQ006KQ1E
    • (2R,4S)-pentane-1,2,3,4,5-pentol
    • INS NO.967
    • Xylooligosaccharide
    • INS-967
    • DTXSID601032335
    • Ribitol (USAN)
    • NSC-16868
    • NSC-25283
    • pentane-1,2,3,4,5-pentol
    • 16277-71-7
    • RIBITOL [USAN]
    • E-967
    • 4-01-00-02832 (Beilstein Handbook Reference)
    • Adonitol;Adonite
    • 1,2,3,4,5-Pentahydroxypentane
    • EINECS 201-788-0
    • NSC 25283
    • UNII-353ZQ9TVDA
    • UNII-VCQ006KQ1E
    • DTXSID7042514
    • BRN 1720523
    • pentitols
    • Adonito
    • meso-Pentitol
    • Xylitol [INN:BAN:JAN:NF]
    • DL-Arabinit
    • Xylitol C
    • HSDB 7967
    • Xylitab DC
    • Wood sugar alcohol
    • ribitol [INN]
    • RB0
    • Xylitol, Meso-xylitol, C-Xylidex CR 16055, DL-Xylitol, Eutrit, Fluorette, Klinit, Kylit, NSC 25283, Wood sugar alcohol, X 0018, Xylisorb, Xylisorb 300, Xylisorb 700, Xylit, Xylit XC, Xylitab 100, Xylitab 300, Xylitab DC, Xylite, Xylite (sugar), Xylitol C, Xylitol CM 90, Xylitol P, Xyliton, meso-Xylitol, xylo-Pentitol
    • Xylitol (Standard)
    • Adonitol (7CI)
    • Xylisorb 300
    • Xylisorb 700
    • Xylitab 100
    • Xylitol - BP/EP
    • Adonitol, >=99%
    • E967
    • XYLITOL [VANDF]
    • Xylitol, >=99%
    • XYLITOL [FCC]
    • XYLITOL [JAN]
    • XYLITOL [II]
    • XYLITOL [MI]
    • XYLITOL [MART.]
    • XYLITOL [USP-RS]
    • XYLITOL [WHO-DD]
    • bmse000062
    • bmse000129
    • bmse000886
    • Epitope ID:114702
    • Epitope ID:114703
    • EC 201-788-0
    • SCHEMBL4250
    • Xylitol, analytical standard
    • 1,2,3,4,5Pentanepentol
    • SCHEMBL15318
    • MLS002695898
    • CHEMBL96783
    • Ribitol (6CI,8CI,9CI)
    • XYLITOL [EP IMPURITY]
    • XYLITOL [EP MONOGRAPH]
    • QSPL 191
    • SCHEMBL1924966
    • CHEMBL1865120
    • CHEMBL3137744
    • DTXCID5022514
    • CHEBI:25899
    • HY-N0538R
    • BBP-418

  • Applications

    Adonitol (CAS 488-81-3) is a sugar alcohol (polyol) used primarily as a substrate in clinical microbiology fermentation tests (adonitol fermentation test) to differentiate among bacteria, as a building block or intermediate in carbohydrate synthesis and pharmaceutical development, and as a reference standard for analytical determinations of sugar alcohols (HPLC/GC); it may also be used as a humectant or excipient in cosmetics and pharmaceutical formulations, subject to formulation requirements and local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 7.46
    methanol 36.32
    isopropanol 3.34
    water 1310.46
    ethyl acetate 0.88
    n-propanol 4.24
    acetone 0.73
    n-butanol 2.55
    acetonitrile 0.93
    DMF 103.01
    toluene 0.1
    isobutanol 2.01
    1,4-dioxane 5.96
    methyl acetate 0.75
    THF 2.86
    2-butanone 0.89
    n-pentanol 1.08
    sec-butanol 2.92
    n-hexane 0.13
    ethylene glycol 159.58
    NMP 81.13
    cyclohexane 0.7
    DMSO 296.27
    n-butyl acetate 0.57
    n-octanol 1.24
    chloroform 0.51
    n-propyl acetate 0.4
    acetic acid 11.33
    dichloromethane 0.84
    cyclohexanone 2.57
    propylene glycol 50.46
    isopropyl acetate 0.58
    DMAc 52.0
    2-ethoxyethanol 13.47
    isopentanol 1.39
    n-heptane 0.66
    ethyl formate 1.14
    1,2-dichloroethane 0.94
    n-hexanol 1.58
    2-methoxyethanol 45.84
    isobutyl acetate 0.2
    tetrachloromethane 0.37
    n-pentyl acetate 0.58
    transcutol 11.42
    n-heptanol 1.75
    ethylbenzene 0.13
    MIBK 0.51
    2-propoxyethanol 8.98
    tert-butanol 2.54
    MTBE 0.73
    2-butoxyethanol 6.22
    propionic acid 6.71
    o-xylene 0.32
    formic acid 199.41
    diethyl ether 0.79
    m-xylene 0.19
    p-xylene 0.16
    chlorobenzene 0.12
    dimethyl carbonate 2.41
    n-octane 0.26
    formamide 117.58
    cyclopentanone 3.0
    2-pentanone 0.75
    anisole 0.37
    cyclopentyl methyl ether 1.61
    gamma-butyrolactone 5.85
    1-methoxy-2-propanol 20.4
    pyridine 0.99
    3-pentanone 1.08
    furfural 7.12
    n-dodecane 0.14
    diethylene glycol 34.14
    diisopropyl ether 0.35
    tert-amyl alcohol 2.75
    acetylacetone 1.37
    n-hexadecane 0.15
    acetophenone 0.73
    methyl propionate 2.05
    isopentyl acetate 0.43
    trichloroethylene 0.88
    n-nonanol 1.14
    cyclohexanol 3.81
    benzyl alcohol 1.25
    2-ethylhexanol 1.01
    isooctanol 1.31
    dipropyl ether 1.15
    1,2-dichlorobenzene 0.27
    ethyl lactate 3.01
    propylene carbonate 2.3
    n-methylformamide 32.09
    2-pentanol 1.46
    n-pentane 0.23
    1-propoxy-2-propanol 5.72
    1-methoxy-2-propyl acetate 1.93
    2-(2-methoxypropoxy) propanol 5.21
    mesitylene 0.27
    ε-caprolactone 3.51
    p-cymene 0.43
    epichlorohydrin 2.58
    1,1,1-trichloroethane 0.23
    2-aminoethanol 71.67
    morpholine-4-carbaldehyde 54.4
    sulfolane 42.5
    2,2,4-trimethylpentane 0.18
    2-methyltetrahydrofuran 1.59
    n-hexyl acetate 0.71
    isooctane 0.09
    2-(2-butoxyethoxy)ethanol 7.29
    sec-butyl acetate 0.29
    tert-butyl acetate 0.69
    decalin 0.2
    glycerin 167.17
    diglyme 12.19
    acrylic acid 11.84
    isopropyl myristate 0.34
    n-butyric acid 3.45
    acetyl acetate 0.65
    di(2-ethylhexyl) phthalate 0.88
    ethyl propionate 0.64
    nitromethane 9.52
    1,2-diethoxyethane 1.19
    benzonitrile 0.46
    trioctyl phosphate 0.88
    1-bromopropane 0.32
    gamma-valerolactone 10.75
    n-decanol 0.86
    triethyl phosphate 1.14
    4-methyl-2-pentanol 0.8
    propionitrile 0.69
    vinylene carbonate 2.23
    1,1,2-trichlorotrifluoroethane 20.92
    DMS 1.01
    cumene 0.17
    2-octanol 0.96
    2-hexanone 0.37
    octyl acetate 0.51
    limonene 0.79
    1,2-dimethoxyethane 6.69
    ethyl orthosilicate 1.07
    tributyl phosphate 0.68
    diacetone alcohol 3.43
    N,N-dimethylaniline 0.92
    acrylonitrile 1.4
    aniline 0.59
    1,3-propanediol 35.91
    bromobenzene 0.09
    dibromomethane 0.48
    1,1,2,2-tetrachloroethane 1.58
    2-methyl-cyclohexyl acetate 0.7
    tetrabutyl urea 1.55
    diisobutyl methanol 0.93
    2-phenylethanol 1.17
    styrene 0.1
    dioctyl adipate 0.7
    dimethyl sulfate 9.74
    ethyl butyrate 0.74
    methyl lactate 11.51
    butyl lactate 2.02
    diethyl carbonate 0.51
    propanediol butyl ether 8.65
    triethyl orthoformate 1.08
    p-tert-butyltoluene 0.48
    methyl 4-tert-butylbenzoate 2.47
    morpholine 10.04
    tert-butylamine 1.21
    n-dodecanol 0.69
    dimethoxymethane 10.07
    ethylene carbonate 1.87
    cyrene 13.89
    2-ethoxyethyl acetate 0.94
    2-ethylhexyl acetate 0.41
    1,2,4-trichlorobenzene 0.39
    4-methylpyridine 0.55
    dibutyl ether 0.52
    2,6-dimethyl-4-heptanol 0.93
    DEF 7.78
    dimethyl isosorbide 7.43
    tetrachloroethylene 1.61
    eugenol 3.29
    triacetin 1.54
    span 80 6.08
    1,4-butanediol 14.25
    1,1-dichloroethane 0.27
    2-methyl-1-pentanol 0.85
    methyl formate 9.76
    2-methyl-1-butanol 1.77
    n-decane 0.22
    butyronitrile 0.6
    3,7-dimethyl-1-octanol 0.83
    1-chlorooctane 0.36
    1-chlorotetradecane 0.2
    n-nonane 0.24
    undecane 0.17
    tert-butylcyclohexane 0.12
    cyclooctane 0.45
    cyclopentanol 4.61
    tetrahydropyran 1.75
    tert-amyl methyl ether 1.08
    2,5,8-trioxanonane 10.77
    1-hexene 0.15
    2-isopropoxyethanol 4.83
    2,2,2-trifluoroethanol 20.04
    methyl butyrate 0.83

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction