Acetamidoethyl PG-trimonium chloride

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  • Identifiers

    CAS number
    167614-36-0

    Molecular formula
    C10H23ClN2O3

    SMILES
    CC(=O)NCCOCC(C[N+](C)(C)C)O.[Cl-]

    Safety labels

  • Odor profile

    Fragrance
    Odorless 35.08%
    Cooling 29.31%
    Mint 28.28%
    Fishy 27.63%
    Sweet 26.56%
    Savory 25.67%
    Alcoholic 23.25%
    Meaty 18.88%
    Cheesy 18.35%
    Milky 18.06%

     

    Flavor
    Odorless 38.01%
    Mild 29.31%
    Bland 27.86%
    Sulfurous 27.35%
    Sulfury 21.89%
    Sweet-like 21.73%
    Acrid 20.22%
    Yeasty 20.12%
    Catty 19.77%
    Very slight 19.73%

     

    Odor impact est.
    Low

  • Properties

    pKa est.
    6.06 (neutral)

    Molecular weight
    254.75 g/mol

    Flash point

    • -18.49 ˚C est.

  • Synonyms

    • AC quaternized acetamide
    • Quamectant AM-50 PF
    • Acetamidoethyl PG-trimonium chloride
    • UNII-D7ZBF5IN7Q
    • D7ZBF5IN7Q
    • 167614-36-0
    • Acetamidoethyl PG-trimonium chloride [INCI]
    • 1-Propanaminium, 3-(2-(acetylamino)ethoxy)-2-hydroxy-N,N,N-trimethyl-, chloride (1:1)
    • RefChem:199338
    • DTXSID901021228
    • Q27276227
    • 167614-36-0

  • Applications

    Acetamidoethyl PG-trimonium chloride (CAS 167614-36-0) is a quaternary ammonium–based cationic surfactant and conditioning polymer used in a range of industrial and consumer formulations. In cosmetics and personal care, it functions as a conditioning agent for hair and skin, contributing softness and improved feel in shampoos and conditioners. In household products, it acts as a surfactant and fabric conditioning additive, providing anti-static properties in laundry detergents and fabric-care formulations. In industrial manufacturing, it serves as an emulsifier and wetting/dispersion aid in coatings, inks, and polymer processing, helping stabilize emulsions and improve product performance. In polymers/plastics and textiles, it can be used as a processing aid or surface-modifying agent to enhance compatibility, dispersion, and hand feel.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 1315.17
    methanol 4808.84
    isopropanol 219.22
    water 6404.49
    ethyl acetate 21.05
    n-propanol 487.27
    acetone 30.26
    n-butanol 185.3
    acetonitrile 59.14
    DMF 568.85
    toluene 4.21
    isobutanol 133.84
    1,4-dioxane 98.52
    methyl acetate 49.65
    THF 75.62
    2-butanone 22.59
    n-pentanol 46.77
    sec-butanol 113.29
    n-hexane 0.89
    ethylene glycol 2560.99
    NMP 476.15
    cyclohexane 2.97
    DMSO 178.36
    n-butyl acetate 12.33
    n-octanol 15.95
    chloroform 79.4
    n-propyl acetate 11.84
    acetic acid 4581.86
    dichloromethane 68.16
    cyclohexanone 56.76
    propylene glycol 1614.79
    isopropyl acetate 6.88
    DMAc 377.85
    2-ethoxyethanol 343.28
    isopentanol 35.05
    n-heptane 1.29
    ethyl formate 118.19
    1,2-dichloroethane 24.58
    n-hexanol 46.37
    2-methoxyethanol 1580.21
    isobutyl acetate 6.85
    tetrachloromethane 17.98
    n-pentyl acetate 8.93
    transcutol 247.22
    n-heptanol 25.89
    ethylbenzene 1.92
    MIBK 3.33
    2-propoxyethanol 227.7
    tert-butanol 74.77
    MTBE 8.3
    2-butoxyethanol 109.33
    propionic acid 726.83
    o-xylene 4.6
    formic acid 13122.95
    diethyl ether 10.44
    m-xylene 3.39
    p-xylene 2.97
    chlorobenzene 8.79
    dimethyl carbonate 22.54
    n-octane 0.53
    formamide 4397.1
    cyclopentanone 64.57
    2-pentanone 8.55
    anisole 8.43
    cyclopentyl methyl ether 18.9
    gamma-butyrolactone 189.63
    1-methoxy-2-propanol 326.17
    pyridine 70.11
    3-pentanone 8.93
    furfural 278.66
    n-dodecane 0.4
    diethylene glycol 525.65
    diisopropyl ether 1.15
    tert-amyl alcohol 53.51
    acetylacetone 13.19
    n-hexadecane 0.41
    acetophenone 14.47
    methyl propionate 36.89
    isopentyl acetate 8.63
    trichloroethylene 68.41
    n-nonanol 13.81
    cyclohexanol 87.26
    benzyl alcohol 42.51
    2-ethylhexanol 11.79
    isooctanol 13.09
    dipropyl ether 6.57
    1,2-dichlorobenzene 9.29
    ethyl lactate 46.55
    propylene carbonate 88.65
    n-methylformamide 1075.47
    2-pentanol 26.83
    n-pentane 1.55
    1-propoxy-2-propanol 73.82
    1-methoxy-2-propyl acetate 22.6
    2-(2-methoxypropoxy) propanol 58.03
    mesitylene 2.03
    ε-caprolactone 101.23
    p-cymene 3.22
    epichlorohydrin 94.32
    1,1,1-trichloroethane 13.28
    2-aminoethanol 2590.58
    morpholine-4-carbaldehyde 451.59
    sulfolane 173.86
    2,2,4-trimethylpentane 0.74
    2-methyltetrahydrofuran 35.45
    n-hexyl acetate 12.82
    isooctane 0.32
    2-(2-butoxyethoxy)ethanol 89.51
    sec-butyl acetate 4.53
    tert-butyl acetate 6.16
    decalin 0.73
    glycerin 2454.19
    diglyme 129.63
    acrylic acid 1014.45
    isopropyl myristate 3.28
    n-butyric acid 370.02
    acetyl acetate 19.38
    di(2-ethylhexyl) phthalate 15.98
    ethyl propionate 9.76
    nitromethane 1011.74
    1,2-diethoxyethane 11.8
    benzonitrile 19.76
    trioctyl phosphate 9.45
    1-bromopropane 8.92
    gamma-valerolactone 259.41
    n-decanol 8.64
    triethyl phosphate 11.34
    4-methyl-2-pentanol 6.93
    propionitrile 38.95
    vinylene carbonate 121.87
    1,1,2-trichlorotrifluoroethane 577.02
    DMS 18.34
    cumene 1.95
    2-octanol 8.17
    2-hexanone 5.54
    octyl acetate 7.07
    limonene 4.58
    1,2-dimethoxyethane 110.92
    ethyl orthosilicate 10.71
    tributyl phosphate 10.19
    diacetone alcohol 27.98
    N,N-dimethylaniline 8.68
    acrylonitrile 83.38
    aniline 39.28
    1,3-propanediol 1699.42
    bromobenzene 4.54
    dibromomethane 30.03
    1,1,2,2-tetrachloroethane 51.61
    2-methyl-cyclohexyl acetate 13.6
    tetrabutyl urea 14.54
    diisobutyl methanol 3.74
    2-phenylethanol 30.08
    styrene 2.51
    dioctyl adipate 10.37
    dimethyl sulfate 49.92
    ethyl butyrate 10.28
    methyl lactate 127.66
    butyl lactate 31.58
    diethyl carbonate 9.49
    propanediol butyl ether 124.23
    triethyl orthoformate 12.48
    p-tert-butyltoluene 3.35
    methyl 4-tert-butylbenzoate 24.26
    morpholine 265.02
    tert-butylamine 22.85
    n-dodecanol 5.7
    dimethoxymethane 85.37
    ethylene carbonate 78.8
    cyrene 91.39
    2-ethoxyethyl acetate 19.24
    2-ethylhexyl acetate 6.9
    1,2,4-trichlorobenzene 16.12
    4-methylpyridine 32.29
    dibutyl ether 3.72
    2,6-dimethyl-4-heptanol 3.74
    DEF 50.48
    dimethyl isosorbide 65.63
    tetrachloroethylene 68.39
    eugenol 46.81
    triacetin 28.91
    span 80 67.72
    1,4-butanediol 391.6
    1,1-dichloroethane 14.73
    2-methyl-1-pentanol 17.64
    methyl formate 533.77
    2-methyl-1-butanol 59.35
    n-decane 0.66
    butyronitrile 26.86
    3,7-dimethyl-1-octanol 8.5
    1-chlorooctane 2.62
    1-chlorotetradecane 1.06
    n-nonane 0.61
    undecane 0.49
    tert-butylcyclohexane 0.68
    cyclooctane 0.84
    cyclopentanol 139.14
    tetrahydropyran 40.84
    tert-amyl methyl ether 8.44
    2,5,8-trioxanonane 86.08
    1-hexene 2.49
    2-isopropoxyethanol 82.44
    2,2,2-trifluoroethanol 1613.35
    methyl butyrate 18.18

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction