8-Methyl-1-tetralone

Overview IFRA Request a quote

  • Identifiers

    CAS number
    51015-28-2

    Molecular formula
    C11H12O

    SMILES
    CC1=C2C(=CC=C1)CCCC2=O

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Floral 51.38%
    Sweet 46.04%
    Woody 40.87%
    Animal 40.48%
    Powdery 39.39%
    Phenolic 37.17%
    Musk 36.85%
    Hay 36.47%
    Coumarinic 35.59%
    Tobacco 35.39%

     

    Flavor
    Bitter 36.36%
    Minty 28.74%
    Phenolic 27.52%
    Tonka 25.29%
    Herbal 25.2%
    Sweet 24.59%
    Coumarin 24.38%
    Tobacco 23.83%
    Animal 23.48%
    Medicinal 22.2%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.4

    pKa est.
    7.78 (neutral)

    Molecular weight
    160.21 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    281°C

    Flash point

    • 108.3 ˚C est.

  • Synonyms

    • 8-Methyl-1-tetralone
    • 51015-28-2
    • 8-methyl-3,4-dihydro-2H-naphthalen-1-one
    • 1(2H)-Naphthalenone, 3,4-dihydro-8-methyl-
    • 8-methyl-1,2,3,4-tetrahydronaphthalen-1-one
    • UNII-D9W56OZV5G
    • EINECS 256-912-6
    • D9W56OZV5G
    • 3,4-Dihydro-8-methyl-1(2H)-naphthalenone
    • DTXSID5068607
    • 8-Methyl-3,4-dihydro-1(2H)-naphthalenone
    • RefChem:107255
    • DTXCID1040954
    • 256-912-6
    • ACEWUDFEONXYQH-UHFFFAOYSA-N
    • MFCD08234369
    • 8-Methyl-3,4-dihydronaphthalen-1(2H)-one
    • 3,4-Dihydro-8-methylnaphthalen-1(2H)-one
    • 8-methyltetralin-1-one
    • SCHEMBL1337967
    • 3,4-dihydro-8-methyl naphthalenone
    • AKOS006284742
    • CS-W004322
    • SB37423
    • AS-83003
    • Methyl-3,4-dihydronaphthalen-1(2H)-one
    • SY262881
    • DB-360036
    • NS00012249
    • EN300-98053
    • F17727
    • F790727
    • Q27276288
    • 51015-28-2

  • Applications

    8-Methyl-1-tetralone (CAS 51015-28-2) is primarily used as an organic synthesis intermediate, notably in the preparation of pharmaceutical and agrochemical compounds. It also serves as a building block for fragrance and odorant molecules and may be employed as a precursor in flavor chemistry. In cosmetics and personal care, it can be used as an intermediate for fragrance systems. In industrial manufacturing, it provides a versatile core for the synthesis of specialty chemicals and downstream derivatives. It is also used in research and development as a scaffold for more complex aryl ketone compounds, subject to local regulations.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 546.72
    methanol 772.66
    isopropanol 345.99
    water 3.74
    ethyl acetate 917.16
    n-propanol 443.97
    acetone 1281.17
    n-butanol 387.68
    acetonitrile 1398.38
    DMF 1526.75
    toluene 810.48
    isobutanol 300.0
    1,4-dioxane 3189.94
    methyl acetate 922.57
    THF 2429.9
    2-butanone 923.57
    n-pentanol 289.53
    sec-butanol 257.52
    n-hexane 133.92
    ethylene glycol 131.82
    NMP 1421.21
    cyclohexane 211.04
    DMSO 1434.37
    n-butyl acetate 597.93
    n-octanol 234.33
    chloroform 2773.58
    n-propyl acetate 561.78
    acetic acid 525.6
    dichloromethane 3010.84
    cyclohexanone 1778.49
    propylene glycol 87.67
    isopropyl acetate 465.99
    DMAc 569.91
    2-ethoxyethanol 503.76
    isopentanol 287.38
    n-heptane 78.98
    ethyl formate 654.45
    1,2-dichloroethane 2182.99
    n-hexanol 368.74
    2-methoxyethanol 825.48
    isobutyl acetate 339.76
    tetrachloromethane 467.1
    n-pentyl acetate 412.17
    transcutol 1454.36
    n-heptanol 211.0
    ethylbenzene 339.92
    MIBK 456.82
    2-propoxyethanol 712.35
    tert-butanol 315.74
    MTBE 447.95
    2-butoxyethanol 384.36
    propionic acid 428.96
    o-xylene 327.75
    formic acid 202.35
    diethyl ether 1076.68
    m-xylene 450.56
    p-xylene 368.25
    chlorobenzene 993.73
    dimethyl carbonate 412.66
    n-octane 50.07
    formamide 403.33
    cyclopentanone 1968.24
    2-pentanone 825.03
    anisole 620.29
    cyclopentyl methyl ether 1191.46
    gamma-butyrolactone 2119.67
    1-methoxy-2-propanol 550.54
    pyridine 1819.56
    3-pentanone 662.2
    furfural 1393.71
    n-dodecane 38.76
    diethylene glycol 531.41
    diisopropyl ether 257.53
    tert-amyl alcohol 227.25
    acetylacetone 887.54
    n-hexadecane 46.84
    acetophenone 465.72
    methyl propionate 744.08
    isopentyl acetate 436.2
    trichloroethylene 3091.07
    n-nonanol 195.57
    cyclohexanol 473.03
    benzyl alcohol 393.89
    2-ethylhexanol 223.73
    isooctanol 177.87
    dipropyl ether 379.17
    1,2-dichlorobenzene 735.09
    ethyl lactate 207.03
    propylene carbonate 825.29
    n-methylformamide 1010.71
    2-pentanol 250.6
    n-pentane 106.81
    1-propoxy-2-propanol 389.14
    1-methoxy-2-propyl acetate 475.73
    2-(2-methoxypropoxy) propanol 282.35
    mesitylene 284.13
    ε-caprolactone 1246.69
    p-cymene 152.54
    epichlorohydrin 2436.14
    1,1,1-trichloroethane 1415.34
    2-aminoethanol 201.01
    morpholine-4-carbaldehyde 1551.67
    sulfolane 1962.97
    2,2,4-trimethylpentane 42.19
    2-methyltetrahydrofuran 1531.4
    n-hexyl acetate 598.29
    isooctane 46.37
    2-(2-butoxyethoxy)ethanol 468.16
    sec-butyl acetate 327.12
    tert-butyl acetate 476.59
    decalin 97.2
    glycerin 162.88
    diglyme 937.66
    acrylic acid 425.99
    isopropyl myristate 205.25
    n-butyric acid 538.83
    acetyl acetate 483.02
    di(2-ethylhexyl) phthalate 152.3
    ethyl propionate 496.42
    nitromethane 1557.08
    1,2-diethoxyethane 639.91
    benzonitrile 776.97
    trioctyl phosphate 126.93
    1-bromopropane 1044.43
    gamma-valerolactone 2209.37
    n-decanol 147.98
    triethyl phosphate 184.45
    4-methyl-2-pentanol 157.58
    propionitrile 966.33
    vinylene carbonate 879.45
    1,1,2-trichlorotrifluoroethane 760.95
    DMS 496.45
    cumene 192.54
    2-octanol 166.93
    2-hexanone 558.78
    octyl acetate 263.39
    limonene 223.64
    1,2-dimethoxyethane 1055.61
    ethyl orthosilicate 174.07
    tributyl phosphate 159.35
    diacetone alcohol 403.5
    N,N-dimethylaniline 326.32
    acrylonitrile 1208.88
    aniline 625.77
    1,3-propanediol 325.43
    bromobenzene 1128.22
    dibromomethane 1980.52
    1,1,2,2-tetrachloroethane 1741.9
    2-methyl-cyclohexyl acetate 267.45
    tetrabutyl urea 209.98
    diisobutyl methanol 136.21
    2-phenylethanol 373.42
    styrene 461.53
    dioctyl adipate 241.48
    dimethyl sulfate 590.58
    ethyl butyrate 392.53
    methyl lactate 251.12
    butyl lactate 226.9
    diethyl carbonate 258.28
    propanediol butyl ether 292.47
    triethyl orthoformate 251.01
    p-tert-butyltoluene 149.19
    methyl 4-tert-butylbenzoate 345.56
    morpholine 2323.52
    tert-butylamine 225.44
    n-dodecanol 115.95
    dimethoxymethane 1277.17
    ethylene carbonate 779.93
    cyrene 285.85
    2-ethoxyethyl acetate 527.44
    2-ethylhexyl acetate 362.93
    1,2,4-trichlorobenzene 768.25
    4-methylpyridine 1528.85
    dibutyl ether 383.69
    2,6-dimethyl-4-heptanol 136.21
    DEF 880.43
    dimethyl isosorbide 541.74
    tetrachloroethylene 1277.46
    eugenol 340.82
    triacetin 379.97
    span 80 258.54
    1,4-butanediol 153.69
    1,1-dichloroethane 1649.44
    2-methyl-1-pentanol 226.06
    methyl formate 892.1
    2-methyl-1-butanol 272.08
    n-decane 64.31
    butyronitrile 816.59
    3,7-dimethyl-1-octanol 184.14
    1-chlorooctane 257.5
    1-chlorotetradecane 98.4
    n-nonane 67.63
    undecane 49.2
    tert-butylcyclohexane 84.57
    cyclooctane 86.13
    cyclopentanol 504.51
    tetrahydropyran 2027.05
    tert-amyl methyl ether 305.33
    2,5,8-trioxanonane 534.69
    1-hexene 358.86
    2-isopropoxyethanol 336.72
    2,2,2-trifluoroethanol 233.46
    methyl butyrate 616.05

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction