2-Phenylpyridine

Overview IFRA Botanical Request a quote

  • Identifiers

    CAS number
    1008-89-5

    Molecular formula
    C11H9N

    SMILES
    C1=CC=C(C=C1)C2=CC=CC=N2

    Safety labels

    Irritant
    Irritant

  • Odor profile

    Fragrance
    Sweet 66.06%
    Animal 55.04%
    Herbal 55.04%
    Earthy 52.56%
    Tobacco 47.57%
    Musty 45.59%
    Green 44.84%
    Fishy 42.0%
    Burnt 40.06%
    Pungent 39.52%

     

    Flavor
    Herbal 42.15%
    Floral 38.67%
    Tobacco 38.57%
    Sweet 37.5%
    Earthy 36.78%
    Balsam 36.59%
    Green 35.31%
    Rubber 34.72%
    Fecal 34.56%
    Musty 33.69%

     

    Odor impact est.
    High

  • Properties

    XLogP3-AA
    2.6

    pKa est.
    5.06 (weak acid)

    Molecular weight
    155.2 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Slow

    Boiling point est.
    268°C

    Flash point

    • 111.02 ˚C est.

  • Synonyms

    • 2-PHENYLPYRIDINE
    • 1008-89-5
    • Pyridine, 2-phenyl-
    • o-Phenylpyridine
    • 2-phenyl-pyridine
    • 2-(Phenyl-2-D)pyridine
    • EINECS 213-763-1
    • MFCD00006280
    • NSC 89291
    • UNII-2Y6S09838Q
    • NSC-89291
    • 2Y6S09838Q
    • DTXSID6074417
    • 372492-47-2
    • phenylpyridine
    • oPhenylpyridine
    • phenyl pyridine
    • 2-phenyl pyridine
    • Pyridine, 2phenyl
    • NSC89291
    • 2-Phenylpyridine, 98%
    • SCHEMBL35754
    • CHEMBL1193163
    • DTXCID6032560
    • MFCD31699954
    • AKOS005257841
    • AC-5097
    • CS-W007468
    • FP33722
    • AS-14490
    • BP-10684
    • SY017662
    • SY246291
    • DB-006211
    • NS00023005
    • P1039
    • EN300-105801
    • O10850
    • Q18205048
    • Z1255464971
    • 213-763-1

  • Applications

    2-Phenylpyridine (CAS 1008-89-5) is mainly used as a ligand and building block in coordination chemistry to form metal complexes that serve as catalysts for industrial processes such as hydrogenation, cross-coupling, and C–H activation; it also functions as a key scaffold in organic synthesis, especially for heterocyclic and aryl-substituted derivatives with potential in pharmaceutical and agrochemical development. In electronics and materials, 2-Phenylpyridine often acts as a cyclometalating ligand in photoluminescent metal complexes used in OLEDs and related devices. Additionally, it serves as a research reagent and starting point for coordination chemistry and catalysis development, supporting lab-scale studies and process optimization.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 279.25
    methanol 192.65
    isopropanol 164.27
    water 0.44
    ethyl acetate 513.26
    n-propanol 218.94
    acetone 721.25
    n-butanol 197.89
    acetonitrile 528.15
    DMF 838.32
    toluene 359.87
    isobutanol 152.67
    1,4-dioxane 807.55
    methyl acetate 427.49
    THF 913.35
    2-butanone 500.38
    n-pentanol 148.1
    sec-butanol 149.18
    n-hexane 72.05
    ethylene glycol 66.74
    NMP 564.37
    cyclohexane 112.43
    DMSO 980.18
    n-butyl acetate 393.7
    n-octanol 125.27
    chloroform 1461.71
    n-propyl acetate 332.12
    acetic acid 317.73
    dichloromethane 1808.01
    cyclohexanone 795.12
    propylene glycol 75.79
    isopropyl acetate 228.13
    DMAc 569.69
    2-ethoxyethanol 192.64
    isopentanol 155.14
    n-heptane 90.36
    ethyl formate 433.52
    1,2-dichloroethane 1156.1
    n-hexanol 209.25
    2-methoxyethanol 359.44
    isobutyl acetate 187.91
    tetrachloromethane 173.74
    n-pentyl acetate 181.07
    transcutol 941.37
    n-heptanol 105.92
    ethylbenzene 181.99
    MIBK 210.53
    2-propoxyethanol 259.58
    tert-butanol 173.18
    MTBE 186.52
    2-butoxyethanol 160.18
    propionic acid 272.3
    o-xylene 165.68
    formic acid 56.24
    diethyl ether 417.91
    m-xylene 174.8
    p-xylene 189.58
    chlorobenzene 473.22
    dimethyl carbonate 248.13
    n-octane 36.1
    formamide 166.62
    cyclopentanone 846.22
    2-pentanone 406.14
    anisole 309.39
    cyclopentyl methyl ether 382.21
    gamma-butyrolactone 911.16
    1-methoxy-2-propanol 256.22
    pyridine 1048.89
    3-pentanone 345.75
    furfural 735.28
    n-dodecane 27.9
    diethylene glycol 171.57
    diisopropyl ether 97.64
    tert-amyl alcohol 142.73
    acetylacetone 400.32
    n-hexadecane 31.6
    acetophenone 271.46
    methyl propionate 402.45
    isopentyl acetate 264.34
    trichloroethylene 1700.88
    n-nonanol 112.84
    cyclohexanol 202.98
    benzyl alcohol 193.41
    2-ethylhexanol 151.57
    isooctanol 89.74
    dipropyl ether 336.9
    1,2-dichlorobenzene 349.95
    ethyl lactate 115.54
    propylene carbonate 536.11
    n-methylformamide 374.06
    2-pentanol 131.19
    n-pentane 51.64
    1-propoxy-2-propanol 212.35
    1-methoxy-2-propyl acetate 238.46
    2-(2-methoxypropoxy) propanol 168.85
    mesitylene 101.95
    ε-caprolactone 570.23
    p-cymene 105.79
    epichlorohydrin 1014.99
    1,1,1-trichloroethane 640.1
    2-aminoethanol 107.83
    morpholine-4-carbaldehyde 538.12
    sulfolane 854.89
    2,2,4-trimethylpentane 24.02
    2-methyltetrahydrofuran 564.78
    n-hexyl acetate 250.54
    isooctane 20.05
    2-(2-butoxyethoxy)ethanol 243.86
    sec-butyl acetate 173.18
    tert-butyl acetate 186.06
    decalin 55.57
    glycerin 115.16
    diglyme 563.87
    acrylic acid 241.66
    isopropyl myristate 114.06
    n-butyric acid 377.31
    acetyl acetate 260.04
    di(2-ethylhexyl) phthalate 89.32
    ethyl propionate 275.14
    nitromethane 733.8
    1,2-diethoxyethane 391.78
    benzonitrile 351.79
    trioctyl phosphate 69.28
    1-bromopropane 547.76
    gamma-valerolactone 751.08
    n-decanol 91.33
    triethyl phosphate 109.89
    4-methyl-2-pentanol 76.26
    propionitrile 412.01
    vinylene carbonate 491.9
    1,1,2-trichlorotrifluoroethane 456.85
    DMS 226.95
    cumene 106.04
    2-octanol 76.97
    2-hexanone 300.73
    octyl acetate 141.26
    limonene 151.08
    1,2-dimethoxyethane 554.03
    ethyl orthosilicate 100.7
    tributyl phosphate 88.43
    diacetone alcohol 188.86
    N,N-dimethylaniline 193.68
    acrylonitrile 508.87
    aniline 327.35
    1,3-propanediol 157.69
    bromobenzene 546.82
    dibromomethane 1165.69
    1,1,2,2-tetrachloroethane 1116.33
    2-methyl-cyclohexyl acetate 161.01
    tetrabutyl urea 129.8
    diisobutyl methanol 96.5
    2-phenylethanol 177.39
    styrene 267.76
    dioctyl adipate 153.06
    dimethyl sulfate 298.46
    ethyl butyrate 309.93
    methyl lactate 150.83
    butyl lactate 124.51
    diethyl carbonate 196.22
    propanediol butyl ether 131.7
    triethyl orthoformate 165.09
    p-tert-butyltoluene 91.33
    methyl 4-tert-butylbenzoate 180.89
    morpholine 699.93
    tert-butylamine 117.45
    n-dodecanol 76.36
    dimethoxymethane 538.76
    ethylene carbonate 428.12
    cyrene 159.38
    2-ethoxyethyl acetate 224.67
    2-ethylhexyl acetate 208.26
    1,2,4-trichlorobenzene 385.51
    4-methylpyridine 721.41
    dibutyl ether 267.13
    2,6-dimethyl-4-heptanol 96.5
    DEF 489.69
    dimethyl isosorbide 287.61
    tetrachloroethylene 729.92
    eugenol 165.87
    triacetin 203.51
    span 80 148.52
    1,4-butanediol 67.53
    1,1-dichloroethane 821.9
    2-methyl-1-pentanol 128.54
    methyl formate 373.01
    2-methyl-1-butanol 143.7
    n-decane 46.34
    butyronitrile 415.5
    3,7-dimethyl-1-octanol 110.2
    1-chlorooctane 155.32
    1-chlorotetradecane 62.65
    n-nonane 47.82
    undecane 34.9
    tert-butylcyclohexane 44.63
    cyclooctane 43.98
    cyclopentanol 226.89
    tetrahydropyran 724.86
    tert-amyl methyl ether 150.56
    2,5,8-trioxanonane 332.16
    1-hexene 221.62
    2-isopropoxyethanol 135.87
    2,2,2-trifluoroethanol 111.2
    methyl butyrate 405.5

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction

Botanical

Name CAS Botanical Proportion
Cassie absolute 1a extract 8023-82-3 Acacia farnesiana (L.) Willd., fam. Mimosaceae (Leguminosae) 0.5%