2-Hydroxypropyl acrylate

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  • Identifiers

    CAS number
    999-61-1

    Molecular formula
    C6H10O3

    SMILES
    CC(COC(=O)C=C)O

    Safety labels

    Corrosive
    Corrosive

    Acute Toxic
    Acute Toxic

  • Odor profile

    Fragrance
    Caramellic 50.6%
    Buttery 38.74%
    Fruity 34.27%
    Sour 33.01%
    Burnt 32.09%
    Ethereal 30.71%
    Sharp 29.78%
    Odorless 29.75%
    Milky 27.34%
    Sweet 27.27%

     

    Flavor
    Fruity 56.12%
    Odorless 33.79%
    Creamy 27.8%
    Buttery 27.72%
    Sour 25.66%
    Butter 22.98%
    Very mild 22.92%
    Caramel 22.55%
    Roquefort cheese 20.56%
    Musty 20.39%

     

    Odor impact est.
    Medium

  • Properties

    XLogP3-AA
    0.3

    pKa est.
    7.96 (neutral)

    Molecular weight
    130.14 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Moderate

    Boiling point

    • BP: 70 °C at 2 mm Hg
    • BP: 63 °C at 0.04 kPa (0.3 mm Hg)
    • BP: 77 °C at 5 mm Hg
    • 191 °C
    • 376 °F

    Flash point

    • 82.53 ˚C est.
    • 149 °F (closed cup)
    • 65 °C
    • 207 °F
    • 149 °F

    Solubility expt.

    • Miscible with water
    • Miscible with oxygenated solvents
    • Solubility in water, g/100ml at 25 °C: 100 (good)

  • Synonyms

    • 2-HYDROXYPROPYL ACRYLATE
    • 999-61-1
    • 2-hydroxypropyl prop-2-enoate
    • Propylene glycol monoacrylate
    • Acrylic acid, 2-hydroxypropyl ester
    • 1,2-Propanediol, 1-acrylate
    • beta-Hydroxypropyl acrylate
    • 2-Propenoic acid, 2-hydroxypropyl ester
    • EINECS 213-663-8
    • .beta.-Hydroxypropyl acrylate
    • UNII-F17T4R74K6
    • BRN 1754331
    • BISOMER HPA
    • KAYARAD HPA
    • HSDB 7913
    • HOP-A
    • LIGHT ESTER HOP-A
    • DTXSID0022143
    • 2-hydroxy-2-methylethyl acrylate
    • F17T4R74K6
    • 2-Propenoic acid-2-hydroxypropyl ester
    • poly(hydroxypropyl acrylate)
    • MFCD00021900
    • betahydroxypropyl acrylate
    • DSSTox_CID_2143
    • 1,2Propanediol, 1acrylate
    • DSSTox_RID_78601
    • DSSTox_GSID_27878
    • SCHEMBL33585
    • DTXCID802143
    • CHEMBL3184912
    • 2-Hydroxypropyl acrylate (ACGIH)
    • Acrylic acid, 2hydroxypropyl ester
    • Acrylic acid-2-hydroxypropyl ester
    • 1,2-PROPANEDIOL-1-ACRYLATE
    • Tox21_201177
    • 2Propenoic acid, 2hydroxypropyl ester
    • AKOS006230513
    • DS-2693
    • 2-HYDROXYPROPYL ACRYLATE [INCI]
    • propylene glycol monoacrylate homopolymer
    • NCGC00248947-01
    • NCGC00258729-01
    • DA-60140
    • FH139606
    • CAS-25584-83-2
    • NS00010125
    • 2Propenoic acid, 2hydroxypropyl ester (9CI)
    • EN300-197151
    • Q2238032

  • Applications

    2-Hydroxypropyl acrylate (CAS 999-61-1) is used primarily as a reactive diluent and hydroxyl-functional monomer in industrial coatings and polymer formulations. It is commonly employed in UV-curable coatings, inks, and adhesives to reduce formulation viscosity while providing sites for crosslinking. It serves as a building block for polyurethane acrylate (PUA) resins and other acrylate systems, enabling flexible, adherent coatings with good chemical resistance. It also appears in waterborne and solvent-borne acrylate formulations to tailor rheology and functionality. Additional applications include coatings for wood, metal, and plastics; electronics encapsulation and protective coatings; and specialty polyacrylates used in composites and sealants. Use is subject to local regulations and formulation limits.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 265.84
    methanol 492.09
    isopropanol 164.24
    water 40.74
    ethyl acetate 44.5
    n-propanol 153.83
    acetone 132.74
    n-butanol 140.2
    acetonitrile 91.97
    DMF 337.19
    toluene 14.79
    isobutanol 98.55
    1,4-dioxane 176.2
    methyl acetate 74.04
    THF 164.86
    2-butanone 90.78
    n-pentanol 105.89
    sec-butanol 125.92
    n-hexane 6.6
    ethylene glycol 147.32
    NMP 218.45
    cyclohexane 9.2
    DMSO 396.78
    n-butyl acetate 54.61
    n-octanol 56.58
    chloroform 46.4
    n-propyl acetate 41.03
    acetic acid 173.74
    dichloromethane 83.35
    cyclohexanone 98.64
    propylene glycol 109.66
    isopropyl acetate 25.27
    DMAc 307.15
    2-ethoxyethanol 200.5
    isopentanol 107.62
    n-heptane 8.01
    ethyl formate 95.13
    1,2-dichloroethane 58.6
    n-hexanol 84.98
    2-methoxyethanol 321.61
    isobutyl acetate 25.49
    tetrachloromethane 7.04
    n-pentyl acetate 32.86
    transcutol 264.7
    n-heptanol 43.6
    ethylbenzene 19.71
    MIBK 39.04
    2-propoxyethanol 138.13
    tert-butanol 172.27
    MTBE 72.44
    2-butoxyethanol 87.51
    propionic acid 93.86
    o-xylene 22.74
    formic acid 182.21
    diethyl ether 57.6
    m-xylene 15.78
    p-xylene 27.13
    chlorobenzene 22.17
    dimethyl carbonate 26.26
    n-octane 4.1
    formamide 178.56
    cyclopentanone 108.96
    2-pentanone 60.19
    anisole 56.8
    cyclopentyl methyl ether 51.7
    gamma-butyrolactone 121.02
    1-methoxy-2-propanol 168.47
    pyridine 73.96
    3-pentanone 41.66
    furfural 159.68
    n-dodecane 4.58
    diethylene glycol 163.15
    diisopropyl ether 14.04
    tert-amyl alcohol 138.4
    acetylacetone 55.51
    n-hexadecane 4.75
    acetophenone 62.28
    methyl propionate 47.98
    isopentyl acetate 50.03
    trichloroethylene 70.16
    n-nonanol 47.84
    cyclohexanol 75.71
    benzyl alcohol 71.1
    2-ethylhexanol 52.22
    isooctanol 34.92
    dipropyl ether 38.59
    1,2-dichlorobenzene 25.86
    ethyl lactate 43.65
    propylene carbonate 71.77
    n-methylformamide 167.6
    2-pentanol 71.5
    n-pentane 7.59
    1-propoxy-2-propanol 91.25
    1-methoxy-2-propyl acetate 51.53
    2-(2-methoxypropoxy) propanol 108.25
    mesitylene 12.86
    ε-caprolactone 94.55
    p-cymene 18.68
    epichlorohydrin 124.6
    1,1,1-trichloroethane 22.73
    2-aminoethanol 173.44
    morpholine-4-carbaldehyde 230.46
    sulfolane 166.13
    2,2,4-trimethylpentane 5.59
    2-methyltetrahydrofuran 106.27
    n-hexyl acetate 54.04
    isooctane 3.52
    2-(2-butoxyethoxy)ethanol 127.16
    sec-butyl acetate 24.88
    tert-butyl acetate 33.62
    decalin 7.1
    glycerin 151.79
    diglyme 202.93
    acrylic acid 93.17
    isopropyl myristate 26.42
    n-butyric acid 96.17
    acetyl acetate 26.69
    di(2-ethylhexyl) phthalate 38.19
    ethyl propionate 34.68
    nitromethane 180.06
    1,2-diethoxyethane 75.99
    benzonitrile 57.56
    trioctyl phosphate 29.51
    1-bromopropane 32.5
    gamma-valerolactone 166.97
    n-decanol 38.85
    triethyl phosphate 30.96
    4-methyl-2-pentanol 39.5
    propionitrile 69.4
    vinylene carbonate 78.08
    1,1,2-trichlorotrifluoroethane 114.64
    DMS 36.07
    cumene 18.69
    2-octanol 30.22
    2-hexanone 56.86
    octyl acetate 36.87
    limonene 28.74
    1,2-dimethoxyethane 268.19
    ethyl orthosilicate 29.57
    tributyl phosphate 32.8
    diacetone alcohol 76.14
    N,N-dimethylaniline 56.06
    acrylonitrile 87.46
    aniline 39.78
    1,3-propanediol 195.28
    bromobenzene 16.8
    dibromomethane 47.15
    1,1,2,2-tetrachloroethane 61.61
    2-methyl-cyclohexyl acetate 46.5
    tetrabutyl urea 53.95
    diisobutyl methanol 29.97
    2-phenylethanol 56.95
    styrene 22.61
    dioctyl adipate 48.34
    dimethyl sulfate 50.5
    ethyl butyrate 46.13
    methyl lactate 53.6
    butyl lactate 44.56
    diethyl carbonate 35.28
    propanediol butyl ether 97.56
    triethyl orthoformate 37.54
    p-tert-butyltoluene 17.34
    methyl 4-tert-butylbenzoate 62.29
    morpholine 181.04
    tert-butylamine 93.95
    n-dodecanol 32.03
    dimethoxymethane 133.79
    ethylene carbonate 56.88
    cyrene 99.49
    2-ethoxyethyl acetate 49.39
    2-ethylhexyl acetate 37.38
    1,2,4-trichlorobenzene 33.7
    4-methylpyridine 76.44
    dibutyl ether 40.46
    2,6-dimethyl-4-heptanol 29.97
    DEF 110.6
    dimethyl isosorbide 121.23
    tetrachloroethylene 40.48
    eugenol 71.42
    triacetin 56.67
    span 80 82.85
    1,4-butanediol 112.32
    1,1-dichloroethane 33.02
    2-methyl-1-pentanol 94.46
    methyl formate 128.57
    2-methyl-1-butanol 100.26
    n-decane 6.25
    butyronitrile 81.86
    3,7-dimethyl-1-octanol 52.17
    1-chlorooctane 20.68
    1-chlorotetradecane 11.17
    n-nonane 5.85
    undecane 5.2
    tert-butylcyclohexane 6.79
    cyclooctane 3.95
    cyclopentanol 89.88
    tetrahydropyran 93.07
    tert-amyl methyl ether 64.52
    2,5,8-trioxanonane 175.37
    1-hexene 24.03
    2-isopropoxyethanol 111.58
    2,2,2-trifluoroethanol 59.88
    methyl butyrate 63.32

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction