1,2,3-Trideoxy-4,6:5,7-bis-O-((4-propylphenyl)methylene)-nonitol

Overview IFRA Request a quote

  • Identifiers

    CAS number
    882073-43-0

    Molecular formula
    C29H40O6

    SMILES
    CCCC1C2C(C(OC(O2)C3=CC=C(C=C3)CCC)C(CO)O)OC(O1)C4=CC=C(C=C4)CCC

    Safety labels

  • Odor profile

    Fragrance
    Fruity 43.52%
    Sweet 42.68%
    Floral 41.15%
    Green 37.69%
    Herbal 31.01%
    Fresh 25.41%
    Earthy 22.4%
    Jasmin 22.21%
    Balsamic 21.3%
    Animal 21.18%

     

    Flavor
    Green 34.78%
    Bitter 32.38%
    Herbal 32.02%
    Sweet 31.37%
    Floral 26.6%
    Earthy 26.31%
    Fatty 23.99%
    Metallic 23.97%
    Oily 21.95%
    Mild 21.87%

     

    Odor impact est.
    Low

  • Properties

    XLogP3-AA
    5.3

    pKa est.
    5.65 (weak acid)

    Molecular weight
    484.6 g/mol

    Vapor pressure est.

    • hPa @ 20°C
    • hPa @ 25°C

    Evaporation rate
    Ultra slow

    Boiling point est.
    919°C

    Flash point

    • 191.16 ˚C est.

  • Synonyms

    • 882073-43-0
    • D5B9U0YBDI
    • NX 8000K
    • 1,2,3-Trideoxy-4,6:5,7-bis-O-((4-propylphenyl)methylene)-nonitol
    • Nonitol, 1,2,3-trideoxy-4,6:5,7-bis-O-[(4-propylphenyl)methylene]-
    • BIS(4-PROPYLBENZYLIDENE) PROPYL SORBITOL
    • MILLAD NX 8000J
    • MILLAD NX 8000
    • Nonitol, 1,2,3-trideoxy-4,6:5,7-bis-O-((4-propylphenyl)methylene)-
    • 1,2,3-Trideoxy-4,6:5,7-Bis-O-[(4-Propylphenyl)Methylene]-Nonitol
    • 1,2,3-Trideoxy-4,6:5,7-bis-O-[(4-propylphenyl)methylene]nonitol
    • NONITOL, 1,2,3-TRIDEOXY-4,6:5,7-BIS-O-((4-PROPYLPHENYL)METHYLENE)
    • 1,2,3-Trideoxy-4,6:5,7-bis-O-((4-propylphenyl)methylene)nonitol
    • Nonitol, 1,2,3-trideoxy-4,6:5,7-bis-O-((4 propylphenyl)methylene)-
    • Nonitol, 1,2,3-trideoxy-4,6:5,7-bis-O-[(4 propylphenyl)methylene]-
    • RefChem:410844
    • 618-128-6
    • UNII-D5B9U0YBDI
    • 1-(8-Propyl-2,6-bis(4-propylphenyl)tetrahydro-[1,3]dioxino[5,4-d][1,3]dioxin-4-yl)ethane-1,2-diol
    • SCHEMBL195740
    • PIYNPBVOTLQBTC-UHFFFAOYSA-N
    • DTXSID201019882
    • C29H40O6
    • bis(4-propylbenzylidene)propylsorbitol
    • NX 8000
    • CS-0457787
    • Q27276112
    • 1-[8-propyl-2,6-bis(4-propylphenyl)-4,4a,8,8a-tetrahydro-[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
    • 1-[8-Propyl-2,6-bis(4-propylphenyl)tetrahydro-2H,6H-[1,3]dioxino[5,4-d][1,3]dioxin-4-yl]ethane-1,2-diol
    • 882073-43-0

  • Applications

    1,2,3-Trideoxy-4,6:5,7-bis-O-((4-propylphenyl)methylene)-nonitol (CAS 882073-43-0) is primarily used as a diol protective group in carbohydrate synthesis, enabling concurrent protection of hydroxyl groups on the polyol framework and facilitating subsequent transformations. It serves as a precursor or building block for glycoside and glycomimetic derivatives in pharmaceutical R&D, and is also employed as a chiral building block in sophisticated organic synthesis. Additionally, in academic and industrial settings it can function as a reagent for glycosylation strategies and to develop protection/deprotection methodologies, supporting high-value chemical manufacturing and formulation research in fields such as fine chemicals, cosmetics, and pharmaceutical development.

    gpt-5-nano

  • Solubility @25˚C

    Solvent Solubility (g/L)
    ethanol 19.38
    methanol 27.8
    isopropanol 15.48
    water 0.64
    ethyl acetate 134.06
    n-propanol 28.77
    acetone 109.81
    n-butanol 30.64
    acetonitrile 37.01
    DMF 150.95
    toluene 88.89
    isobutanol 24.8
    1,4-dioxane 125.79
    methyl acetate 115.02
    THF 246.63
    2-butanone 116.18
    n-pentanol 29.04
    sec-butanol 27.42
    n-hexane 2.99
    ethylene glycol 7.49
    NMP 357.95
    cyclohexane 8.1
    DMSO 167.37
    n-butyl acetate 81.41
    n-octanol 27.72
    chloroform 380.17
    n-propyl acetate 72.52
    acetic acid 159.57
    dichloromethane 397.67
    cyclohexanone 258.95
    propylene glycol 11.93
    isopropyl acetate 88.1
    DMAc 312.95
    2-ethoxyethanol 66.59
    isopentanol 32.21
    n-heptane 4.3
    ethyl formate 76.12
    1,2-dichloroethane 204.45
    n-hexanol 27.86
    2-methoxyethanol 76.96
    isobutyl acetate 47.46
    tetrachloromethane 52.22
    n-pentyl acetate 116.16
    transcutol 292.51
    n-heptanol 31.03
    ethylbenzene 31.1
    MIBK 69.84
    2-propoxyethanol 77.79
    tert-butanol 23.44
    MTBE 42.29
    2-butoxyethanol 82.79
    propionic acid 92.62
    o-xylene 64.03
    formic acid 55.18
    diethyl ether 50.8
    m-xylene 55.31
    p-xylene 37.14
    chlorobenzene 132.41
    dimethyl carbonate 130.65
    n-octane 2.55
    formamide 75.45
    cyclopentanone 304.7
    2-pentanone 115.39
    anisole 60.65
    cyclopentyl methyl ether 133.57
    gamma-butyrolactone 359.66
    1-methoxy-2-propanol 69.72
    pyridine 155.98
    3-pentanone 118.95
    furfural 299.01
    n-dodecane 2.12
    diethylene glycol 48.57
    diisopropyl ether 19.77
    tert-amyl alcohol 37.87
    acetylacetone 201.34
    n-hexadecane 2.49
    acetophenone 102.41
    methyl propionate 144.4
    isopentyl acetate 79.07
    trichloroethylene 529.16
    n-nonanol 30.16
    cyclohexanol 65.1
    benzyl alcohol 62.08
    2-ethylhexanol 27.09
    isooctanol 29.18
    dipropyl ether 37.71
    1,2-dichlorobenzene 134.77
    ethyl lactate 55.31
    propylene carbonate 208.18
    n-methylformamide 79.29
    2-pentanol 27.31
    n-pentane 3.81
    1-propoxy-2-propanol 65.53
    1-methoxy-2-propyl acetate 119.96
    2-(2-methoxypropoxy) propanol 87.44
    mesitylene 29.43
    ε-caprolactone 263.07
    p-cymene 23.76
    epichlorohydrin 355.08
    1,1,1-trichloroethane 183.73
    2-aminoethanol 17.07
    morpholine-4-carbaldehyde 260.21
    sulfolane 450.16
    2,2,4-trimethylpentane 4.83
    2-methyltetrahydrofuran 145.29
    n-hexyl acetate 101.0
    isooctane 2.26
    2-(2-butoxyethoxy)ethanol 107.79
    sec-butyl acetate 58.26
    tert-butyl acetate 94.34
    decalin 6.09
    glycerin 27.89
    diglyme 218.34
    acrylic acid 109.33
    isopropyl myristate 34.3
    n-butyric acid 131.4
    acetyl acetate 145.36
    di(2-ethylhexyl) phthalate 48.17
    ethyl propionate 78.17
    nitromethane 261.43
    1,2-diethoxyethane 91.17
    benzonitrile 71.49
    trioctyl phosphate 34.75
    1-bromopropane 77.85
    gamma-valerolactone 417.66
    n-decanol 19.95
    triethyl phosphate 53.68
    4-methyl-2-pentanol 20.87
    propionitrile 38.13
    vinylene carbonate 225.15
    1,1,2-trichlorotrifluoroethane 306.59
    DMS 134.69
    cumene 20.05
    2-octanol 24.54
    2-hexanone 69.57
    octyl acetate 50.9
    limonene 36.87
    1,2-dimethoxyethane 99.56
    ethyl orthosilicate 51.35
    tributyl phosphate 41.74
    diacetone alcohol 94.89
    N,N-dimethylaniline 45.67
    acrylonitrile 61.74
    aniline 90.27
    1,3-propanediol 31.08
    bromobenzene 143.47
    dibromomethane 203.25
    1,1,2,2-tetrachloroethane 369.65
    2-methyl-cyclohexyl acetate 67.67
    tetrabutyl urea 52.23
    diisobutyl methanol 18.48
    2-phenylethanol 58.35
    styrene 38.47
    dioctyl adipate 65.02
    dimethyl sulfate 233.4
    ethyl butyrate 74.87
    methyl lactate 96.02
    butyl lactate 92.43
    diethyl carbonate 54.34
    propanediol butyl ether 64.97
    triethyl orthoformate 64.78
    p-tert-butyltoluene 23.29
    methyl 4-tert-butylbenzoate 117.37
    morpholine 131.8
    tert-butylamine 12.71
    n-dodecanol 14.0
    dimethoxymethane 131.17
    ethylene carbonate 185.06
    cyrene 115.25
    2-ethoxyethyl acetate 170.62
    2-ethylhexyl acetate 67.76
    1,2,4-trichlorobenzene 175.5
    4-methylpyridine 153.16
    dibutyl ether 36.08
    2,6-dimethyl-4-heptanol 18.48
    DEF 151.58
    dimethyl isosorbide 161.79
    tetrachloroethylene 250.07
    eugenol 91.48
    triacetin 156.42
    span 80 76.26
    1,4-butanediol 16.81
    1,1-dichloroethane 148.66
    2-methyl-1-pentanol 34.49
    methyl formate 88.14
    2-methyl-1-butanol 37.01
    n-decane 4.02
    butyronitrile 36.05
    3,7-dimethyl-1-octanol 28.63
    1-chlorooctane 23.11
    1-chlorotetradecane 8.26
    n-nonane 3.33
    undecane 2.77
    tert-butylcyclohexane 4.32
    cyclooctane 4.45
    cyclopentanol 66.95
    tetrahydropyran 116.92
    tert-amyl methyl ether 54.67
    2,5,8-trioxanonane 145.29
    1-hexene 12.57
    2-isopropoxyethanol 54.61
    2,2,2-trifluoroethanol 111.65
    methyl butyrate 94.28

    Scent© AI

1 4

IFRA standard 51

Recommendation
No restriction
Maximum acceptable concentrations in the finished product (%)
Category 1
Products applied to the lips
 No restriction Category 7A
Rinse-off products applied to the hair with some hand contact
 No restriction
Category 2
Products applied to the axillae
 No restriction Category 7B
Leave-on products applied to the hair with some hand contact
 No restriction
Category 3
Products applied to the face/body using fingertips
 No restriction Category 8
Products with significant anogenital exposure
 No restriction
Category 4
Products related to fine fragrance
 No restriction Category 9
Products with body and hand exposure, primarily rinse off
 No restriction
Category 5A
Body lotion products applied to the body using the hands (palms), primarily leave on
 No restriction Category 10A
Household care products with mostly hand contact
 No restriction
Category 5B
Face moisturizer products applied to the face using the hands (palms), primarily leave on
 No restriction Category 10B
Household care products with mostly hand contact, including aerosol/spray products (with potential leave-on skin contact)
 No restriction
Category 5C
Hand cream products applied to the hands using the hands (palms), primarily leave on
 No restriction Category 11A
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate without UV exposure
 No restriction
Category 5D
Baby Creams, baby Oils and baby talc
 No restriction Category 11B
Products with intended skin contact but minimal transfer of fragrance to skin from inert substrate with potential UV exposure
 No restriction
Category 6
Products with oral and lip exposure
 No restriction Category 12
Products not intended for direct skin contact, minimal or insignificant transfer to skin
 No restriction